Senarai Penerbitan mengikut label - National Autism Resource Centre (NARC)

Eow, S Y; Gan, W Y; Lim, P Y; Awang, H; Shariff, Mohd Z

Faktor-faktor yang berkaitan dengan keparahan autisme di kalangan kanak-kanak Malaysia dengan Autism Spectrum Disorder Artikel Jurnal

Penyelidikan Ketidakupayaan Pembangunan, 100 , 2020, ISSN: 08914222, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Berat badan, Anak-anak, Kajian Lintas Bahagian, Demografi, Persatuan Penyakit, Keterukan Penyakit, Pekerjaan, Perempuan, Manusia, Gaya hidup, Kajian Klinikal Utama, Malaysia, Orang Malaysia, Lelaki, Ibu bapa, Kanak-kanak Prasekolah, Budak sekolah, Status sosial

@artikel{Eow2020,
tajuk = {Faktor-faktor yang berkaitan dengan keparahan autisme di kalangan kanak-kanak Malaysia dengan Autism Spectrum Disorder},
pengarang = {S Y Eow dan W Y Gan dan P Y Lim dan H Awang dan Z Mohd Shariff},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-85081212440&doi = 10.1016% 2fj.ridd.2020.103632&rakan kongsi = 40&md5 = a2814a66b9d649278ea7f764ed7e4125},
doi = {10.1016/j.ridd.2020.103632},
terbitan = {08914222},
tahun = {2020},
tarikh = {2020-01-01},
jurnal = {Penyelidikan Ketidakupayaan Pembangunan},
isi padu = {100},
penerbit = {Elsevier Inc.},
abstrak = {Latar belakang: Kanak-kanak dengan Gangguan Spektrum Autisme (ASD) tahap keparahan gejala yang berlainan boleh menunjukkan pelbagai tingkah laku dan ciri. Terdapat kajian berkaitan pemakanan terhad pada kanak-kanak dengan ASD dengan tahap keparahan yang berbeza di Malaysia. Matlamat: Kajian keratan rentas ini bertujuan untuk mengetahui perkaitan antara faktor sosiodemografi, faktor ibu bapa, dan faktor gaya hidup dengan keparahan autisme pada kanak-kanak dengan ASD. Kaedah dan prosedur: Sejumlah 224 kanak-kanak dengan ASD dimasukkan dalam kajian ini. Ibu mereka melengkapkan borang soal selidik mengenai ciri sosiodemografi, keterukan autisme, gaya keibubapaan, amalan memberi makan ibu bapa, tekanan keibubapaan, tabiat tidur anak dan tingkah laku makan. Hasil dan hasil: Setinggi 78.1 % kanak-kanak dengan ASD menunjukkan tahap keparahan autisme yang tinggi. Regresi linear berganda menunjukkan bahawa status pekerjaan bapa (B = 6.970, 95 % CI = 3.172, 10.768, hlm < 0.001) and perceived child weight (B = 3.338, 95 % CI = 1.350, 5.327},
nota = {dipetik oleh 0},
kata kunci = {Artikel, Autisme, Berat badan, Anak-anak, Kajian Lintas Bahagian, Demografi, Persatuan Penyakit, Keterukan Penyakit, Pekerjaan, Perempuan, Manusia, Gaya hidup, Kajian Klinikal Utama, Malaysia, Orang Malaysia, Lelaki, Ibu bapa, Kanak-kanak Prasekolah, Budak sekolah, Status sosial},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Singh, Balbir H K; Badgujar, V B; Yahaya, R S; Rahman, Abd S; Bersendirian, F M; Badgujar, S; Govindan, S N; Ansari, M T

Assessment of knowledge and attitude among postnatal mothers towards childhood vaccination in Malaysia Artikel Jurnal

Human Vaccines and Immunotherapeutics, 15 (11), hlm. 2544-2551, 2019, ISSN: 21645515, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Attitude, Sikap Terhadap Kesihatan, Autisme, Child Health, Childhood Vaccination, Anak-anak, Kajian Lintas Bahagian, Diphtheria Pertussis Poliomyelitis Tetanus Haemophilus Influenzae Type B Hepatitis B Vaccine, Pendidikan, Pekerjaan, Etnik, Perempuan, Health Knowledge, Manusia, Immunization Programs, Pengetahuan, Skala Likert, Kajian Klinikal Utama, Malaysia, Ibu, Mothers, Needs Assessment, Occupation, Postnatal Care, Practice, Kanak-kanak Prasekolah, Preventive Health Service, Psikologi, Soal selidik, Seasonal Influenza, Tinjauan, Vaccination, Dewasa Muda

@artikel{BalbirSingh20192544,
tajuk = {Assessment of knowledge and attitude among postnatal mothers towards childhood vaccination in Malaysia},
pengarang = {H K Balbir Singh and V B Badgujar and R S Yahaya and S Abd Rahman and F M Sami and S Badgujar and S N Govindan and M T Ansari},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067899547&doi=10.1080%2f21645515.2019.1612666&rakan kongsi = 40&md5=2da8ecc4fd4df251566a2f8b2454e763},
doi = {10.1080/21645515.2019.1612666},
terbitan = {21645515},
tahun = {2019},
tarikh = {2019-01-01},
jurnal = {Human Vaccines and Immunotherapeutics},
isi padu = {15},
nombor = {11},
halaman = {2544-2551},
penerbit = {Taylor dan Francis Inc.},
abstrak = {Aim: Mothers knowledge and attitude toward childhood vaccination influence uptake is the most adequate tool and preventive aspects to infectious disease epidemics. The present study assesses and measures knowledge and attitude of postnatal mothers toward vaccination. Methods and results: The present study adopted a cross-sectional study design, whereby 200 postnatal mothers were identified during their postnatal visit to clinics. The subjects were accessed using questionnaire to assess the level of knowledge and attitude of mothers regarding vaccination. The objectives were to study the level of knowledge, the attitude, and to find the association between knowledge and attitude of the study subjects. The data were analyzed using SPSS version 16. The results was analyzed through chi-square test. The association between age (p =.031), pendidikan (p =.021), occupation (p =.013), and knowledge score toward vaccination was found to be statistically significant. Walau bagaimanapun, ethnicity (p =.127), employment (p =.197), and mode of delivery (p =.750) toward mothers vaccination knowledge were not significant for the study. Mothers education, age, and occupation were found to be associated with attitude toward childhood vaccination. No association was found between ethnicity, employment, and mode of delivery with attitude of childhood vaccination. Kesimpulannya: More than half of the studied mothers had good knowledge scores on vaccination, more than two-thirds of the studied mothers had good attitude scores on vaccination. Walau bagaimanapun, the religious misconception and fear of autism was the main cause of vaccine resistance in Malaysia. © 2019, © 2019 Kumpulan Taylor & Francis, LLC.},
nota = {dipetik oleh 0},
kata kunci = {Remaja, Dewasa, Artikel, Attitude, Sikap Terhadap Kesihatan, Autisme, Child Health, Childhood Vaccination, Anak-anak, Kajian Lintas Bahagian, Diphtheria Pertussis Poliomyelitis Tetanus Haemophilus Influenzae Type B Hepatitis B Vaccine, Pendidikan, Pekerjaan, Etnik, Perempuan, Health Knowledge, Manusia, Immunization Programs, Pengetahuan, Skala Likert, Kajian Klinikal Utama, Malaysia, Ibu, Mothers, Needs Assessment, Occupation, Postnatal Care, Practice, Kanak-kanak Prasekolah, Preventive Health Service, Psikologi, Soal selidik, Seasonal Influenza, Tinjauan, Vaccination, Dewasa Muda},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Ong, BUKAN PERKATAAN

Kepuasan ibu bapa dan persepsi terhadap Kemajuan dalam mempengaruhi Amalan pendekatan kesihatan pelengkap pada kanak-kanak autisme: Tinjauan keratan rentas dari Negeri Sembilan, Malaysia Artikel Jurnal

Perubatan Komplementari dan Alternatif BMC, 19 (1), 2019, ISSN: 14726882, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Ubatan alternatif, Autisme, Gangguan Spektrum Autisme, Tingkah Laku Kanak-kanak, Hubungan Ibu Bapa Anak, Anak-anak, Terapi Pelengkap, Kajian Lintas Bahagian, Perempuan, Manusia, Bayi, Malaysia, Lelaki, Pertengahan umur, Ibu bapa, Kepuasan Peribadi, Prasekolah, Kanak-kanak Prasekolah, Psikologi, Soal selidik, Kepuasan hati, Kecekapan Sosial, Kemahiran sosial, Tinjauan, Hasil Rawatan

@artikel{Ong2019,
tajuk = {Kepuasan ibu bapa dan persepsi terhadap Kemajuan dalam mempengaruhi Amalan pendekatan kesihatan pelengkap pada kanak-kanak autisme: Tinjauan keratan rentas dari Negeri Sembilan, Malaysia},
pengarang = {J J Ong},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071968009&doi = 10.1186% 2fs12906-019-2672-8&rakan kongsi = 40&md5=7357d9aa26c64a321790fee9aae89765},
doi = {10.1186/s12906-019-2672-8},
terbitan = {14726882},
tahun = {2019},
tarikh = {2019-01-01},
jurnal = {Perubatan Komplementari dan Alternatif BMC},
isi padu = {19},
nombor = {1},
penerbit = {BioMed Central Ltd.},
abstrak = {Latar belakang: Penggunaan pendekatan kesihatan pelengkap oleh ibu bapa (TIDAK) untuk kanak-kanak yang mengalami gangguan spektrum autisme (ASD) adalah perkara biasa walaupun terdapat bukti yang tidak pasti tentang manfaatnya. Ibu bapa sering mengamalkan CHA kerana tidak berpuas hati dengan rawatan konvensional. Kajian ini bertujuan untuk mengkaji kepuasan ibu bapa terhadap rawatan ASD dan persepsi mereka terhadap kemajuan dalam perkembangan anak mereka.. Penggunaan CHA oleh ibu bapa dalam kalangan kanak-kanak dengan ASD dan faktor-faktor yang berkaitan juga dinilai. Kaedah: Soal selidik yang ditadbir sendiri telah dilengkapkan oleh 48 ibu bapa yang mempunyai anak ASD di hospital rujukan tertiari tunggal di Malaysia. Analisis korelasi digunakan untuk meneroka perkaitan antara skor kepuasan ibu bapa, persepsi skor kemajuan dan penggunaan CHA. Keputusan: Penggunaan CHA dilaporkan oleh ibu bapa untuk 35.4% kanak-kanak dengan ASD dalam sampel. Ibu bapa yang kurang berpuas hati dengan rawatan konvensional dan ibu bapa yang merasakan kemajuan yang lebih lemah dalam perkembangan anak mereka lebih cenderung menggunakan CHA. Hubungan positif yang kukuh didapati antara kepuasan ibu bapa dengan skor rawatan ASD dan persepsi ibu bapa terhadap skor kemajuan, yang menunjukkan bahawa ibu bapa yang berpuas hati dengan rawatan lebih cenderung untuk melihat kemajuan yang lebih besar dalam perkembangan anak mereka. Peningkatan dalam kemajuan anak amat dihargai oleh ibu bapa dalam tingkah laku anak mereka (85.5%), kemahiran sosial (83.3%) dan kemahiran motor (77.1%). Kesimpulannya: Penggunaan CHA adalah biasa di kalangan kanak-kanak dengan ASD. Ibu bapa lebih cenderung untuk mengamalkan CHA apabila mereka kurang berpuas hati dengan rawatan konvensional dan merasakan kemajuan yang lebih buruk. Kajian berbilang pusat yang lebih besar diperlukan untuk meneroka lebih lanjut amalan CHA dalam kalangan kanak-kanak ASD di seluruh Malaysia. © 2019 Pengarang(s).},
nota = {dipetik oleh 0},
kata kunci = {Remaja, Dewasa, Ubatan alternatif, Autisme, Gangguan Spektrum Autisme, Tingkah Laku Kanak-kanak, Hubungan Ibu Bapa Anak, Anak-anak, Terapi Pelengkap, Kajian Lintas Bahagian, Perempuan, Manusia, Bayi, Malaysia, Lelaki, Pertengahan umur, Ibu bapa, Kepuasan Peribadi, Prasekolah, Kanak-kanak Prasekolah, Psikologi, Soal selidik, Kepuasan hati, Kecekapan Sosial, Kemahiran sosial, Tinjauan, Hasil Rawatan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Jaafar, N H; Othman, A; Majid, N A; Harith, S; Zabidi-Hussin, DENGAN

Parent-report instruments for assessing feeding difficulties in children with neurological impairments: a systematic review Artikel Jurnal

Developmental Medicine and Child Neurology, 61 (2), hlm. 135-144, 2019, ISSN: 00121622, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: Assessment of Humans, Autisme, Behavioural Paediatric Feeding Assessment Scale, Caloric Intake, Tingkah Laku Kanak-kanak, Hubungan Ibu Bapa Anak, Childhood Disease, Anak-anak, Children's Eating Behaviour Inventory, Komplikasi, Construct Validity, Content Validity, Criterion Related Validity, Cystic Fibrosis, Gangguan Makan, Enalapril Maleate, Eosinophilic Gastrointestinal Disorder, Esophagus Atresia, Feeding, Feeding and Eating Disorders, Tingkah Laku Makan, Kesukaran Memberi Makan, Pengambilan makanan, Manusia, Nervous System Diseases, Neurologic Disease, Penilaian Pemakanan, Ibu bapa, Pediatric Assessment Scale for Severe Feeding Problem, Pediatric Eating Assessment Tool, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Psikometrik, Psikometri, Kualiti hidup, Receiver Operating Characteristic, Kaji semula, Sistem Pemarkahan, Self Disclosure, Kepekaan dan Kekhususan, Syndrome CHARGE, Kajian Sistematik, Test Retest Reliability

@artikel{Jaafar2019135,
tajuk = {Parent-report instruments for assessing feeding difficulties in children with neurological impairments: a systematic review},
pengarang = {N H Jaafar and A Othman and N A Majid and S Harith and Z Zabidi-Hussin},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052789833&doi=10.1111%2fdmcn.13986&rakan kongsi = 40&md5=d02a2bfcd15a25988b9c23855cd87444},
doi = {10.1111/dmcn.13986},
terbitan = {00121622},
tahun = {2019},
tarikh = {2019-01-01},
jurnal = {Developmental Medicine and Child Neurology},
isi padu = {61},
nombor = {2},
halaman = {135-144},
penerbit = {Blackwell Publishing Ltd},
abstrak = {Aim: This study aimed to review the psychometric properties and clinical application of parent-report instruments that assess feeding difficulties in children with neurological impairments. Kaedah: Papers were identified through five electronic databases based on 15 keywords and were included if they met the following criteria: published in English, described the implementation of parent-report instruments, and included children with neurological impairments (either in the report or a related study population). Keputusan: In total, 1220 relevant abstracts were screened and 22 full-text articles were evaluated. The following six parent-report instruments met the inclusion criteria: (1) Screening Tool of Feeding Problems applied to children, (2) Paediatric Eating Assessment Tool, (3) Paediatric Assessment Scale for Severe Feeding Problems, (4) Montreal Children's Hospital Feeding Scale, (5) Children's Eating Behaviour Inventory, dan (6) Behavioural Paediatric Feeding Assessment Scale (BPFAS). Based on comprehensive psychometric testing and consistently good results, the BPFAS was considered the most valid and reliable instrument. The BPFAS also showed good clinical applicability because it was readily available, required a short administration time, and used a simple scoring system. Interpretation: We reviewed the available parent-report instruments for assessing feeding difficulties in children with neurological impairments. The BPFAS had the best psychometric properties and clinical applicability. What this paper adds: Six parent-report instruments were suitable for assessing feeding in children with neurological impairments. The Behavioural Paediatric Feeding Assessment Scale (BPFAS) has the strongest psychometric properties. The BPFAS also has good clinical applicability. © 2018 Mac Keith Press},
nota = {dipetik oleh 1},
kata kunci = {Assessment of Humans, Autisme, Behavioural Paediatric Feeding Assessment Scale, Caloric Intake, Tingkah Laku Kanak-kanak, Hubungan Ibu Bapa Anak, Childhood Disease, Anak-anak, Children's Eating Behaviour Inventory, Komplikasi, Construct Validity, Content Validity, Criterion Related Validity, Cystic Fibrosis, Gangguan Makan, Enalapril Maleate, Eosinophilic Gastrointestinal Disorder, Esophagus Atresia, Feeding, Feeding and Eating Disorders, Tingkah Laku Makan, Kesukaran Memberi Makan, Pengambilan makanan, Manusia, Nervous System Diseases, Neurologic Disease, Penilaian Pemakanan, Ibu bapa, Pediatric Assessment Scale for Severe Feeding Problem, Pediatric Eating Assessment Tool, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Psikometrik, Psikometri, Kualiti hidup, Receiver Operating Characteristic, Kaji semula, Sistem Pemarkahan, Self Disclosure, Kepekaan dan Kekhususan, Syndrome CHARGE, Kajian Sistematik, Test Retest Reliability},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Cth, N A N; Ibrahim, M Saya; Rahman, A A; Bakar ia, R S; Yahaya, N A; Hussin, S; Mansor, Wan W N A

Tekanan yang dirasakan dalam kalangan penjaga kanak-kanak yang mengalami gangguan spektrum autisme: Kajian seluruh negeri Artikel Jurnal

Jurnal Antarabangsa Penyelidikan Alam Sekitar dan Kesihatan Awam, 16 (8), 2019, ISSN: 16617827, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Adaptasi, Remaja, Dewasa, Artikel, Autisme, Gangguan Spektrum Autisme, Pengasuh, Beban Penjaga, Penjagaan Kanak-kanak, Anak-anak, Tingkah Laku Menghadapi, Kajian Lintas Bahagian, Perempuan, Susulan, Penjagaan Kesihatan, Akses Penjagaan Kesihatan, Manusia, Bayi, Gangguan Pembelajaran, Malaysia, Lelaki, Tekanan Mental, Pertengahan umur, Analisis Regresi Linear Berganda, Baru lahir, Manusia Biasa, Pengangkutan Pesakit, Skala Tekanan yang Diperhatikan, Ramalan, Prasekolah, Kanak-kanak Prasekolah, Psikologi, Psikologi, Psikometrik, Psikometri, Kualiti hidup, Tekanan, Pusat Jagaan Tertiari, Hospital Universiti

@artikel{Adib2019b,
tajuk = {Tekanan yang dirasakan dalam kalangan penjaga kanak-kanak yang mengalami gangguan spektrum autisme: Kajian seluruh negeri},
pengarang = {N A N Adib dan M I Ibrahim dan A A Rahman dan R S Bakar dan N A Yahaya dan S Hussin dan W N A Wan Mansor},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065303613&doi = 10.3390% 2fijerph16081468&rakan kongsi = 40&md5=fc871375f0d307a95820cd87c57ea270},
doi = {10.3390/ijerph16081468},
terbitan = {16617827},
tahun = {2019},
tarikh = {2019-01-01},
jurnal = {Jurnal Antarabangsa Penyelidikan Alam Sekitar dan Kesihatan Awam},
isi padu = {16},
nombor = {8},
penerbit = {MDPI AG},
abstrak = {Latar belakang: Penjaga kanak-kanak yang mengalami gangguan spektrum autisme (ASD) mengalami tekanan yang meningkat dan akibat pengasuhan negatif yang lebih ketara daripada mereka yang mempunyai kanak-kanak yang sedang membangun. Terdapat kekurangan kajian yang khusus memfokuskan kepada tekanan dalam kalangan penjaga yang mempunyai kanak-kanak ASD di negara Asia. Kajian semasa mengkaji tahap tekanan yang dirasakan dan faktor yang dikaitkan dengannya dalam kalangan penjaga di Kelantan, Malaysia. Kaedah: Dalam kajian keratan rentas, versi Bahasa Melayu bagi Skala Tekanan Yang Diperhatikan (PSS) telah ditadbirkan kepada 227 penjaga kanak-kanak dengan ASD. Pengasuh telah diambil daripada pangkalan data ASD di empat hospital tertiari di Kelantan dan satu mesyuarat telah diadakan semasa susulan kanak-kanak itu di klinik.. Analisis regresi linear berbilang telah digunakan untuk menentukan peramal tekanan yang dirasakan. Keputusan: Purata jumlah skor tekanan yang dirasakan ialah 20.84 (4.72). Ini dianggap lebih tinggi daripada purata. Tekanan yang dirasakan lebih tinggi telah diramalkan dengan ketara dalam kalangan penjaga yang tinggal jauh dari institusi kesihatan, penjaga yang tidak memiliki pengangkutan untuk membawa anak ke pusat rawatan, dan penjaga yang mempunyai anak ASD dengan masalah pembelajaran. Kesimpulannya: Pengasuh kanak-kanak ASD merasakan tekanan yang ketara semasa menjaga anak-anak mereka. Institusi harus mengurangkan faktor-faktor yang diramalkan meningkatkan tekanan pengasuh untuk meningkatkan kualiti kehidupan kanak-kanak dan keluarga ASD secara keseluruhan.. © 2019 oleh pengarang. MDPI pemegang lesen, Basel, Switzerland.},
nota = {dipetik oleh 0},
kata kunci = {Adaptasi, Remaja, Dewasa, Artikel, Autisme, Gangguan Spektrum Autisme, Pengasuh, Beban Penjaga, Penjagaan Kanak-kanak, Anak-anak, Tingkah Laku Menghadapi, Kajian Lintas Bahagian, Perempuan, Susulan, Penjagaan Kesihatan, Akses Penjagaan Kesihatan, Manusia, Bayi, Gangguan Pembelajaran, Malaysia, Lelaki, Tekanan Mental, Pertengahan umur, Analisis Regresi Linear Berganda, Baru lahir, Manusia Biasa, Pengangkutan Pesakit, Skala Tekanan yang Diperhatikan, Ramalan, Prasekolah, Kanak-kanak Prasekolah, Psikologi, Psikologi, Psikometrik, Psikometri, Kualiti hidup, Tekanan, Pusat Jagaan Tertiari, Hospital Universiti},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Tsuchida, N; Hamada, K; Shiina, M; Kato, M; Kobayashi, Y; Tohyama, J; Kimura, K; Hoshino, K; Ganesan, V; Teik, K W; Nakashima, M; Mitsuhashi, S; Mizuguchi, T; Takata, A; Miyake, N; Saitsu, H; Ogata, K; Miyatake, S; Matsumoto, N

GRIN2D variants in three cases of developmental and epileptic encephalopathy Artikel Jurnal

Clinical Genetics, 94 (6), hlm. 538-547, 2018, ISSN: 00099163, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing

@artikel{Tsuchida2018538,
tajuk = {GRIN2D variants in three cases of developmental and epileptic encephalopathy},
pengarang = {N Tsuchida and K Hamada and M Shiina and M Kato and Y Kobayashi and J Tohyama and K Kimura and K Hoshino and V Ganesan and K W Teik and M Nakashima and S Mitsuhashi and T Mizuguchi and A Takata and N Miyake and H Saitsu and K Ogata and S Miyatake and N Matsumoto},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056487337&doi=10.1111%2fcge.13454&rakan kongsi = 40&md5=f0d32670db57261820bc244943cffd62},
doi = {10.1111/cge.13454},
terbitan = {00099163},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {Clinical Genetics},
isi padu = {94},
nombor = {6},
halaman = {538-547},
penerbit = {Blackwell Publishing Ltd},
abstrak = {N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Baru-baru ini, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. Dalam kajian ini, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd},
nota = {dipetik oleh 4},
kata kunci = {Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Diurut, R

Tingkah laku merangsang dalam kanak-kanak perempuan berusia 4 tahun dengan gangguan spektrum autisme Artikel Jurnal

Laporan Kes BMJ, 2018 , 2018, ISSN: 1757790X, (dipetik oleh 0).

Pautan | BibTeX | Tag: Autisme, Gangguan Spektrum Autisme, biskut, Menggigit Objek Keras, Laporan kes, Mainan Kunyah, Keselamatan Kanak-kanak, Anak-anak, Artikel Klinikal, Perempuan, Makanan, Tekstur Makanan, Makanan panas, Manusia, Ketidakupayaan Bahasa, Nota, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Psikologi, Rangsangan Diri, Makanan pedas, Kelakuan Stereotaip, Stereotaip, Tingkah Laku Merangsang, Biskut Tumbuh Gigi, sayur

Toh, T -H; Tan, V W -Y; Lau, PST; Kiyu, A

Ketepatan Senarai Semak Perubahan untuk Autisme pada Kanak-kanak (M-CHAT) dalam Mengesan Autisme dan Gangguan Perkembangan Lain di Klinik Komuniti Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 48 (1), hlm. 28-35, 2018, ISSN: 01623257, (dipetik oleh 9).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Penilaian Autisme, Gangguan Spektrum Autisme, Senarai semak, Anak-anak, Analisis Kohort, Kajian Kohort, Pusat Kesihatan Komuniti, Gangguan Perkembangan, Ketepatan Diagnostik, Perempuan, Pusat kesihatan, Manusia, Bayi, Kajian Klinikal Utama, Malaysia, Lelaki, Pemeriksaan Massa, Senarai Semak yang Diubahsuai untuk Autisme pada Kanak-kanak, Hospital Pediatrik, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Kajian Retrospektif, Kajian Retrospektif, Kepekaan dan Kekhususan, Piawaian, Kanak-kanak kecil

@artikel{Toh201828,
tajuk = {Ketepatan Senarai Semak Perubahan untuk Autisme pada Kanak-kanak (M-CHAT) dalam Mengesan Autisme dan Gangguan Perkembangan Lain di Klinik Komuniti},
pengarang = {T -H Toh dan V W -Y Tan dan P S -T Lau dan A Kiyu},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-85028764085&doi=10.1007/s10803-017-3287-x&rakan kongsi = 40&md5 = 21bce2407197b8b1e43b4420d274861b},
doi = {10.1007/s10803-017-3287-x},
terbitan = {01623257},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {Jurnal Autisme dan Gangguan Perkembangan},
isi padu = {48},
nombor = {1},
halaman = {28-35},
penerbit = {Springer New York LLC},
abstrak = {Kajian ini menentukan ketepatan Senarai Semak Modifikasi untuk Autisme pada Balita (M-CHAT) dalam mengesan balita dengan gangguan spektrum autisme (ASD) dan gangguan perkembangan lain (DD) di klinik kesihatan ibu dan anak. Kami menganalisis 19,297 kanak-kanak yang layak (15–36 bulan) yang telah melakukan M-CHAT pada tahun 2006-2011. Sensitiviti keseluruhan untuk mengesan ASD dan semua DD adalah lemah tetapi lebih baik pada 21 ke <27 months and 27–36-month age cohorts (54.5–64.3%). Although positive predictive value (PPV) was poor for ASD, especially the younger cohort, positive M-CHAT helped in detecting all DD (PPV = 81.6%). This suggested M-CHAT for screening ASD was accurate for older cohorts (>21 bulan) dan alat saringan yang berguna untuk semua DD. © 2017, Springer Science + Media Perniagaan, LLC.},
nota = {dipetik oleh 9},
kata kunci = {Artikel, Autisme, Penilaian Autisme, Gangguan Spektrum Autisme, Senarai semak, Anak-anak, Analisis Kohort, Kajian Kohort, Pusat Kesihatan Komuniti, Gangguan Perkembangan, Ketepatan Diagnostik, Perempuan, Pusat kesihatan, Manusia, Bayi, Kajian Klinikal Utama, Malaysia, Lelaki, Pemeriksaan Massa, Senarai Semak yang Diubahsuai untuk Autisme pada Kanak-kanak, Hospital Pediatrik, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Kajian Retrospektif, Kajian Retrospektif, Kepekaan dan Kekhususan, Piawaian, Kanak-kanak kecil},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Hnoonual, A; Thammachote, W; Tim-Aroon, T; Rojnueangnit, K; Hansakunachai, T; Sombuntham, T; Roongpraiwan, R; Vorachotekamjorn, J; Chuthapisith, J; Fucharoen, S; Wattanasirichaigoon, D; Ruangdaraganon, N; Limprasert, P; Jinawath, N

Analisis microarray kromosom dalam kohort populasi yang kurang diwakili mengenal pasti SERINC2 sebagai gen calon baru untuk gangguan spektrum autisme Artikel Jurnal

Laporan Saintifik, 7 (1), 2017, ISSN: 20452322, (dipetik oleh 6).

Abstrak | Pautan | BibTeX | Tag: Remaja, Autisme, Gangguan Spektrum Autisme, Anak-anak, Pemetaan Kromosom, Pemetaan Kromosom, Analisis Kohort, Kajian Kohort, Variasi Nombor Salin, Variasi Nombor Salinan DNA, Perempuan, Kecenderungan Genetik, Kecenderungan Genetik kepada Penyakit, Genetik, Manusia, Bayi, Lelaki, Protein Membran, Protein Membran, Analisis Mikroarray, Polimorfisme, Prasekolah, Kanak-kanak Prasekolah, Prosedur, SERINC2 Protein, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal

@artikel{Hnoual2017,
tajuk = {Analisis microarray kromosom dalam kohort populasi yang kurang diwakili mengenal pasti SERINC2 sebagai gen calon baru untuk gangguan spektrum autisme},
pengarang = {A Hnoonual dan W Thammachote dan T Tim-Aroon dan K Rojnueangnit dan T Hansakunachai dan T Sombuntham dan R Roongpraiwan dan J Worachotekamjorn dan J Chuthapisith dan S Fucharoen dan D Wattanasirichaigoon dan N Ruangdaraganon dan P Limprasert dan N Jinawath},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029864969&doi=10.1038/s41598-017-12317-3&rakan kongsi = 40&md5=3c1b6a0c064665aab8ace8e8f58c2b01},
doi = {10.1038/s41598-017-12317-3},
terbitan = {20452322},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {Laporan Saintifik},
isi padu = {7},
nombor = {1},
penerbit = {Kumpulan Penerbitan Alam},
abstrak = {Mikroarray kromosom (CMA) kini diiktiraf sebagai ujian genetik peringkat pertama untuk pengesanan variasi nombor salinan (CNV) pada pesakit dengan gangguan spektrum autisme (ASD). Matlamat kajian ini adalah untuk mengenal pasti ASD-CNV yang diketahui dan baru yang berkaitan dan untuk menilai hasil diagnostik CMA dalam pesakit Thai dengan ASD. Infinium CytoSNP-850K BeadChip telah digunakan untuk mengesan CNV dalam 114 Pesakit Thai terdiri daripada 68 pesakit ASD retrospektif (kumpulan 1) dengan penggunaan CMA sebagai ujian baris kedua dan 46 bakal pesakit ASD dan kelewatan perkembangan (kumpulan 2) dengan penggunaan CMA sebagai ujian peringkat pertama. Kami mengenal pasti 7 (6.1%) CNV patogenik dan 22 (19.3%) varian kepentingan klinikal yang tidak pasti (ANDA). Sejumlah 29 pesakit dengan CNV patogen dan VOUS ditemui di 22% (15/68) dan 30.4% (14/46) daripada pesakit dalam kumpulan 1 dan 2, masing-masing. Perbezaan frekuensi CNV yang dikesan antara 2 kumpulan tidak signifikan secara statistik (Chi kuasa dua = 1.02},
nota = {dipetik oleh 6},
kata kunci = {Remaja, Autisme, Gangguan Spektrum Autisme, Anak-anak, Pemetaan Kromosom, Pemetaan Kromosom, Analisis Kohort, Kajian Kohort, Variasi Nombor Salin, Variasi Nombor Salinan DNA, Perempuan, Kecenderungan Genetik, Kecenderungan Genetik kepada Penyakit, Genetik, Manusia, Bayi, Lelaki, Protein Membran, Protein Membran, Analisis Mikroarray, Polimorfisme, Prasekolah, Kanak-kanak Prasekolah, Prosedur, SERINC2 Protein, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Singh, Joginder S; Hussein, N H; Kamal, Mustaffa R; Hassan, F H

Reflections of Malaysian parents of children with developmental disabilities on their experiences with AAC Artikel Jurnal

AAC: Augmentative and Alternative Communication, 33 (2), hlm. 110-120, 2017, ISSN: 07434618, (dipetik oleh 10).

Abstrak | Pautan | BibTeX | Tag: Dewasa, Sikap Terhadap Kesihatan, Augmentative and Alternative Communication, Anak-anak, Communication Aid, Communication Aids for Disabled, Gangguan Komunikasi, Communication Disorders, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Disabilities, Penyakit, Keluarga, Perempuan, Manusia, Human Rehabilitation Engineering, Malaysia, Lelaki, Pertengahan umur, Ibu bapa, Prasekolah, Kanak-kanak Prasekolah, Qualitative Research

@artikel{JoginderSingh2017110,
tajuk = {Reflections of Malaysian parents of children with developmental disabilities on their experiences with AAC},
pengarang = {S Joginder Singh and N H Hussein and R Mustaffa Kamal and F H Hassan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017131769&doi=10.1080%2f07434618.2017.1309457&rakan kongsi = 40&md5=067c39e0c318e76caff96b29bb4dbb21},
doi = {10.1080/07434618.2017.1309457},
terbitan = {07434618},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {AAC: Augmentative and Alternative Communication},
isi padu = {33},
nombor = {2},
halaman = {110-120},
penerbit = {Taylor and Francis Ltd},
abstrak = {Parents play an important role in the successful implementation of AAC. Previous research has indicated that parents in different countries have varying perceptions about the use of AAC and face different challenges in its implementation. Sehingga kini, there is limited information about the use of AAC by children in Malaysia or parents’ views about its use. The aim of this study was to explore Malaysian parents’ perception of AAC and their experience when supporting their children who use AAC. Untuk kajian ini, 12 parents of children with autism spectrum disorder and cerebral palsy were involved in semi-structured individual interviews. Qualitative content analysis was used to analyze interview data. Following analysis, three themes were identified: (a) impact of the use of AAC, (b) challenges faced, dan (c) hopes and expectations. Participants reported that the use of AAC had a positive impact on their children, but that they faced challenges related to the child, the settings, and the system itself, as well as a lack of time and support. Findings from this study provide an insight for Malaysian speech therapists about the challenges faced by parents when supporting their children who use AAC, and how important it is to overcome these challenges to ensure successful implementation of AAC. © 2017 International Society for Augmentative and Alternative Communication.},
nota = {dipetik oleh 10},
kata kunci = {Dewasa, Sikap Terhadap Kesihatan, Augmentative and Alternative Communication, Anak-anak, Communication Aid, Communication Aids for Disabled, Gangguan Komunikasi, Communication Disorders, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Disabilities, Penyakit, Keluarga, Perempuan, Manusia, Human Rehabilitation Engineering, Malaysia, Lelaki, Pertengahan umur, Ibu bapa, Prasekolah, Kanak-kanak Prasekolah, Qualitative Research},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Shuib, S; Saaid, N N; Zakaria, DENGAN; Ismail, J; Latiff, Abdul Z

Penduaan 17p11.2 (Sindrom Potocki-Lupski) pada kanak-kanak yang mengalami kelewatan perkembangan Artikel Jurnal

Jurnal Patologi Malaysia, 39 (1), hlm. 77-81, 2017, ISSN: 01268635, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Keabnormalan, Agarose, Artikel, Autisme, Gangguan Spektrum Autisme, Budaya Darah, Laporan kes, Anak-anak, Kromosom 17, Analisis Kromosom, Gangguan Kromosom, Penduaan Kromosom, Kromosom, Artikel Klinikal, Hibridisasi Genomik Perbandingan, Kelewatan Perkembangan, Elektroforesis, Perempuan, Pendarfluor, Pendarfluor dalam Hibridisasi Situ, Gen, Pengenalan Gen, Genetik, DNA genomik, Manusia, Hibridisasi In Situ, Kultur Limfosit, Analisis Mikroarray, Pelbagai, Sindrom Malformasi Pelbagai, berpasangan 17, Fenotip, Sindrom Potocki Lupski, Prasekolah, Kanak-kanak Prasekolah, Prosedur, Gen RAI1, Spektrofotometri ultraungu

@artikel{Shuib201777,
tajuk = {Penduaan 17p11.2 (Sindrom Potocki-Lupski) pada kanak-kanak yang mengalami kelewatan perkembangan},
pengarang = {S Shuib and N N Saaid and Z Zakaria and J Ismail and Z Abdul Latiff},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037028880&rakan kongsi = 40&md5=624b87d1e9ebac2d1bf66b4d30c0f6e9},
terbitan = {01268635},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {Jurnal Patologi Malaysia},
isi padu = {39},
nombor = {1},
halaman = {77-81},
penerbit = {Persatuan Pakar Patologi Malaysia},
abstrak = {Sindrom Potocki-Lupski (PTLS), juga dikenali sebagai sindrom duplikasi 17p11.2, trisomi 17p11.2 atau dup(17)(p11.2p11.2) sindrom, adalah gangguan perkembangan dan sindrom gen bersebelahan yang jarang menjejaskan 1 dalam 20,000 kelahiran hidup. Antara ciri utama pesakit tersebut ialah gangguan spektrum autisme, ketidakupayaan pembelajaran, kelewatan perkembangan, gangguan kurang perhatian, hipotonia bayi dan keabnormalan kardiovaskular. Kajian terdahulu menggunakan microarray mengenal pasti variasi dalam saiz dan takat kawasan pendua kromosom 17p11.2. Walau bagaimanapun, terdapat beberapa gen yang dianggap sebagai calon PTLS termasuk RAI1, SREBF1, DRG2, LLGL1, SHMT1 dan ZFP179. Dalam laporan ini, kami menyiasat kes seorang kanak-kanak perempuan berumur 3 tahun yang mengalami kelewatan perkembangan. Analisis kromosomnya menunjukkan karyotype normal (46,XX). Analisis menggunakan tatasusunan CGH (4X44 K, Agilent USA) mengenal pasti pertindihan ~4.2 Mb de novo dalam kromosom 17p11.2. Hasilnya disahkan oleh hibridisasi in situ pendarfluor (IKAN) menggunakan probe di kawasan PTLS kritikal. Laporan ini menunjukkan kepentingan microarray dan FISH dalam diagnosis PTLS. © 2017, Persatuan Pakar Patologi Malaysia. Hak cipta terpelihara.},
nota = {dipetik oleh 0},
kata kunci = {Keabnormalan, Agarose, Artikel, Autisme, Gangguan Spektrum Autisme, Budaya Darah, Laporan kes, Anak-anak, Kromosom 17, Analisis Kromosom, Gangguan Kromosom, Penduaan Kromosom, Kromosom, Artikel Klinikal, Hibridisasi Genomik Perbandingan, Kelewatan Perkembangan, Elektroforesis, Perempuan, Pendarfluor, Pendarfluor dalam Hibridisasi Situ, Gen, Pengenalan Gen, Genetik, DNA genomik, Manusia, Hibridisasi In Situ, Kultur Limfosit, Analisis Mikroarray, Pelbagai, Sindrom Malformasi Pelbagai, berpasangan 17, Fenotip, Sindrom Potocki Lupski, Prasekolah, Kanak-kanak Prasekolah, Prosedur, Gen RAI1, Spektrofotometri ultraungu},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Charara, R; Forouzanfar, M; Naghavi, M; Moradi-Lakeh, M; Afshin, A; Anda, T; Daoud, F; Wang, H; Bcheraoui, TERDAPAT; Khalil, Saya; Hamadeh, R R; Khosravi, A; Rahimi-Movaghar, V; Khader, Y; Al-Hamad, N; Obermeyer, C M; Rafay, A; Asghar, R; Rana, S M; Shaheen, A; Abu-Rmeileh, N M E; Husseini, A; Abu-Raddad, L J; Khoja, T; Rayess, Z A A; AlBuhairan, F S; Hsairi, M; Alomari, M A; Tetapi, R; Roshandel, G; Terkawi, A S; Hamidi, S; Refaat, A H; Westerman, R; Kiadaliri, A A; Akanda, A S; Tetapi, S D; Bacha, U; Badawi, A; Bazargan-Hejazi, S; Faghmous, Saya A D; Fereshtehnejad, S -M; Fischer, F; Jonas, J B; Lalai, B K; Mehari, A; Omer, S B; Pourmalek, F; Uthman, Wahai A; Mokdad, A A; Maalouf, F T; Abd-Allah, F; Akseer, N; Arya, D; Borschmann, R; Brazinova, A; Brugha, T S; Catala-Lopez, F; Degenhardt, L; Ferrari, A; Haro, J M; Horino, M; Hornberger, J C; Huang, H; Kieling, C; Kim, D; Kim, Y; Knudsen, Seorang K; Mitchell, P B; Patton, G; Sagar, R; Satpati, M; Savuon, K; Seedat, S; Shiue, Saya; Hutan, J C; Stein, D J; Tabb, K M; Whiteford, H A; Yip, P; Yonemoto, N; Murray, C J L; Mokdad, A H

The burden of mental disorders in the eastern mediterranean region, 1990-2013 Artikel Jurnal

PLoS SATU, 12 (1), 2017, ISSN: 19326203, (dipetik oleh 30).

Abstrak | Pautan | BibTeX | Tag: 80 and Over, Remaja, Dewasa, umur, Faktor Umur, Aged, Anxiety Disorder, Artikel, Gangguan Defisit Perhatian, Autisme, Bipolar Disorder, Anak-anak, Conduct Disorder, Kemurungan, Elderly People, Perempuan, Global Health, Groups by Age, Status kesihatan, Highest Income Group, Manusia, Bayi, Kemerosotan Intelektual, Kuwait, Life Expectancy, Kajian Klinikal Utama, Lelaki, Mediterranean Region, Mental Disease, Gangguan Mental, Kesihatan mental, Perkhidmatan Kesihatan Mental, Pertengahan umur, Middle Income Group, Mortality, Baru lahir, Palestine, Premature Mortality, Prasekolah, Kanak-kanak Prasekolah, Kelaziman, Qatar, Quality Adjusted Life Year, Skizofrenia, Sex Difference, Faktor Seks, Southern Europe, Time Factor, Time Factors, United Arab Emirates, Dewasa Muda

@artikel{Charara2017,
tajuk = {The burden of mental disorders in the eastern mediterranean region, 1990-2013},
pengarang = {R Charara and M Forouzanfar and M Naghavi and M Moradi-Lakeh and A Afshin and T Vos and F Daoud and H Wang and C E Bcheraoui and I Khalil and R R Hamadeh and A Khosravi and V Rahimi-Movaghar and Y Khader and N Al-Hamad and C M Obermeyer and A Rafay and R Asghar and S M Rana and A Shaheen and N M E Abu-Rmeileh and A Husseini and L J Abu-Raddad and T Khoja and Z A A Rayess and F S AlBuhairan and M Hsairi and M A Alomari and R Ali and G Roshandel and A S Terkawi and S Hamidi and A H Refaat and R Westerman and A A Kiadaliri and A S Akanda and S D Ali and U Bacha and A Badawi and S Bazargan-Hejazi and I A D Faghmous and S -M Fereshtehnejad and F Fischer and J B Jonas and B K Defo and A Mehari and S B Omer and F Pourmalek and O A Uthman and A A Mokdad and F T Maalouf and F Abd-Allah and N Akseer and D Arya and R Borschmann and A Brazinova and T S Brugha and F Catala-Lopez and L Degenhardt and A Ferrari and J M Haro and M Horino and J C Hornberger and H Huang and C Kieling and D Kim and Y Kim and A K Knudsen and P B Mitchell and G Patton and R Sagar and M Satpathy and K Savuon and S Seedat and I Shiue and J C Skogen and D J Stein and K M Tabb and H A Whiteford and P Yip and N Yonemoto and C J L Murray and A H Mokdad},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009892168&doi=10.1371/journal.pone.0169575&rakan kongsi = 40&md5=471830ec1239e37c6fc4681bed5698f6},
doi = {10.1371/jurnal.pone.0169575},
terbitan = {19326203},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {PLoS SATU},
isi padu = {12},
nombor = {1},
penerbit = {Perpustakaan Awam Sains},
abstrak = {The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost-YLLs) and nonfatal outcomes (years lived with disability-YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. Dalam 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 jantan, 2426/100,000 perempuan) in high-income countries, 1884 DALYS/100,000 (1618/100,000 jantan, 2157/100,000 perempuan) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 jantan, 1717/100,000 perempuan) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25-49 age group, with a peak in the 35-39 years age group (5344 DALYs/100,000). The burden of mental disorders Burden of Mental Disorders in EMR PLOS ONE in EMR increased from 1726 DALYs/100,000 in 1990 ke 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Lebih-lebih lagi, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Sesungguhnya, mental health problems, if not properly addressed, will lead to an increased burden of diseases in the region. © 2017 Charara et al. Ini ialah artikel akses terbuka yang diedarkan di bawah syarat Lesen Atribusi Creative Commons, yang membenarkan penggunaan tanpa had, pengedaran, dan pembiakan dalam mana-mana medium, dengan syarat penulis dan sumber asal dikreditkan.},
nota = {dipetik oleh 30},
kata kunci = {80 and Over, Remaja, Dewasa, umur, Faktor Umur, Aged, Anxiety Disorder, Artikel, Gangguan Defisit Perhatian, Autisme, Bipolar Disorder, Anak-anak, Conduct Disorder, Kemurungan, Elderly People, Perempuan, Global Health, Groups by Age, Status kesihatan, Highest Income Group, Manusia, Bayi, Kemerosotan Intelektual, Kuwait, Life Expectancy, Kajian Klinikal Utama, Lelaki, Mediterranean Region, Mental Disease, Gangguan Mental, Kesihatan mental, Perkhidmatan Kesihatan Mental, Pertengahan umur, Middle Income Group, Mortality, Baru lahir, Palestine, Premature Mortality, Prasekolah, Kanak-kanak Prasekolah, Kelaziman, Qatar, Quality Adjusted Life Year, Skizofrenia, Sex Difference, Faktor Seks, Southern Europe, Time Factor, Time Factors, United Arab Emirates, Dewasa Muda},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost-YLLs) and nonfatal outcomes (years lived with disability-YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. Dalam 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 jantan, 2426/100,000 perempuan) in high-income countries, 1884 DALYS/100,000 (1618/100,000 jantan, 2157/100,000 perempuan) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 jantan, 1717/100,000 perempuan) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25-49 age group, with a peak in the 35-39 years age group (5344 DALYs/100,000). The burden of mental disorders Burden of Mental Disorders in EMR PLOS ONE in EMR increased from 1726 DALYs/100,000 in 1990 ke 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Lebih-lebih lagi, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Sesungguhnya, mental health problems, if not properly addressed, will lead to an increased burden of diseases in the region. © 2017 Charara et al. Ini ialah artikel akses terbuka yang diedarkan di bawah syarat Lesen Atribusi Creative Commons, yang membenarkan penggunaan tanpa had, pengedaran, dan pembiakan dalam mana-mana medium, dengan syarat penulis dan sumber asal dikreditkan.

Tutup

Pelik, B; Jomhari, N; Ahmad, R

Visual Hybrid Development Learning System (VHDLS) Framework for Children with Autism Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 45 (10), hlm. 3069-3084, 2015, ISSN: 01623257, (dipetik oleh 7).

Abstrak | Pautan | BibTeX | Tag: Artikel, Perhatian, Autisme, Gangguan Spektrum Autisme, Anak-anak, Computer Interface, Pendidikan, Education of Intellectually Disabled, Educational Model, Feedback System, Perempuan, Manusia, Belajar, Lelaki, Models, Occupational Therapist, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Kualiti hidup, Treatment Duration, Antara Muka Pengguna, Visual Hybrid Development Learning System, Visual Stimulation

Batt, S; Acharya, U R; Adeli, H; Tenusu, G M; Adeli, A

Autisme: Cause factors, early diagnosis and therapies Artikel Jurnal

Reviews in the Neurosciences, 25 (6), hlm. 841-850, 2014, ISSN: 03341763, (dipetik oleh 52).

Abstrak | Pautan | BibTeX | Tag: 4 Aminobutyric Acid, Remaja, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Artikel, Teknologi Bantuan, Perhatian, Autisme, Gangguan Spektrum Autisme, Behaviour Therapy, Penanda Biologi, Otak, Gangguan Perkembangan Kanak-kanak, Anak-anak, Kognisi, Cystine, Gangguan Perkembangan, Penyakit, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emosi, Ekspresi wajah, Pengimejan Resonans Magnetik Berfungsi, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Manusia, Bayi, Komunikasi Interpersonal, Methionine, Keradangan Sistem Saraf, Neurobiology, Neurofeedback, Oxidative Stress, Meresap, Fisiologi, Kanak-kanak Prasekolah, Jurnal Keutamaan, Psychoeducation, Budak sekolah, Interaksi Sosial, Terapi ucapan, Realiti maya, Zonisamide

@artikel{Bhat2014841,
tajuk = {Autisme: Cause factors, early diagnosis and therapies},
pengarang = {S Bhat and U R Acharya and H Adeli and G M Bairy and A Adeli},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925284617&doi=10.1515%2frevneuro-2014-0056&rakan kongsi = 40&md5=caaa32e66af70e70ec325241d01564c9},
doi = {10.1515/revneuro-2014-0056},
terbitan = {03341763},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Reviews in the Neurosciences},
isi padu = {25},
nombor = {6},
halaman = {841-850},
penerbit = {Walter de Gruyter GmbH},
abstrak = {Gangguan spektrum autisme (ASD) is a complex neurobiological disorder characterized by neuropsychological and behavioral deficits. Cognitive impairment, lack of social skills, and stereotyped behavior are the major autistic symptoms, visible after a certain age. It is one of the fastest growing disabilities. Its current prevalence rate in the U.S. estimated by the Centers for Disease Control and Prevention is 1 dalam 68 births. The genetic and physiological structure of the brain is studied to determine the pathology of autism, but diagnosis of autism at an early age is challenging due to the existing phenotypic and etiological heterogeneity among ASD individuals. Volumetric and neuroimaging techniques are explored to elucidate the neuroanatomy of the ASD brain. Nuroanatomical, neurochemical, and neuroimaging biomarkers can help in the early diagnosis and treatment of ASD. This paper presents a review of the types of autism, etiologies, early detection, and treatment of ASD. © 2014 Walter de Gruyter GmbH.},
nota = {dipetik oleh 52},
kata kunci = {4 Aminobutyric Acid, Remaja, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Artikel, Teknologi Bantuan, Perhatian, Autisme, Gangguan Spektrum Autisme, Behaviour Therapy, Penanda Biologi, Otak, Gangguan Perkembangan Kanak-kanak, Anak-anak, Kognisi, Cystine, Gangguan Perkembangan, Penyakit, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emosi, Ekspresi wajah, Pengimejan Resonans Magnetik Berfungsi, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Manusia, Bayi, Komunikasi Interpersonal, Methionine, Keradangan Sistem Saraf, Neurobiology, Neurofeedback, Oxidative Stress, Meresap, Fisiologi, Kanak-kanak Prasekolah, Jurnal Keutamaan, Psychoeducation, Budak sekolah, Interaksi Sosial, Terapi ucapan, Realiti maya, Zonisamide},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Chen, B C; Rawi, Mohd R; Meinsma, R; Meijer, J; Hennekam, R C M; Kuilenburg, Van A B P

Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings Artikel Jurnal

Molecular Syndromology, 5 (6), hlm. 299-303, 2014, ISSN: 16618769, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Alanine, Artikel, Asymptomatic Disease, Autisme, Autosomal Recessive Disorder, Laporan kes, Cerebellum Atrophy, Anak-anak, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Keterukan Penyakit, DPYD Gene, Eye Malformation, Perempuan, Gen, Gene Mutation, Homozygosity, Manusia, Kemerosotan Intelektual, Orang Malaysia, Lelaki, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Kanak-kanak Prasekolah, Pyrimidine, Pyrimidine Metabolism, Budak sekolah, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil

@artikel{Chen2014299,
tajuk = {Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings},
pengarang = {B C Chen and R Mohd Rawi and R Meinsma and J Meijer and R C M Hennekam and A B P Van Kuilenburg},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919783242&doi=10.1159%2f000366074&rakan kongsi = 40&md5=1ebfb9aedb7cb64e3423811b41b6aa7c},
doi = {10.1159/000366074},
terbitan = {16618769},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Molecular Syndromology},
isi padu = {5},
nombor = {6},
halaman = {299-303},
penerbit = {S. Karger AG},
abstrak = {Dihydropyrimidine dehydrogenase (DPD) deficiency is an autosomal recessive disorder of the pyrimidine metabolism. Deficiency of this enzyme leads to an accumulation of thymine and uracil and a deficiency of metabolites distal to the catabolic enzyme. The disorder presents with a wide clinical spectrum, ranging from asymptomatic to severe neurological manifestations, termasuk kecacatan intelektual, seizures, microcephaly, autistic behavior, and eye abnormalities. Di sini, we report on an 11-year-old Malaysian girl and her 6-year-old brother with DPD deficiency who presented with intellectual disability, microcephaly, and hypotonia. Brain MRI scans showed generalized cerebral and cerebellar atrophy and callosal body dysgenesis in the boy. Urine analysis showed strongly elevated levels of uracil in the girl and boy (571 dan 578 mmol/mol creatinine, masing-masing) and thymine (425 dan 427 mmol/mol creatinine, masing-masing). Sequence analysis of the DPYD gene showed that both siblings were homozygous for the mutation c.1651G>A (pAla551Thr). © 2014 S. Karger AG, Basel.},
nota = {dipetik oleh 4},
kata kunci = {Alanine, Artikel, Asymptomatic Disease, Autisme, Autosomal Recessive Disorder, Laporan kes, Cerebellum Atrophy, Anak-anak, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Keterukan Penyakit, DPYD Gene, Eye Malformation, Perempuan, Gen, Gene Mutation, Homozygosity, Manusia, Kemerosotan Intelektual, Orang Malaysia, Lelaki, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Kanak-kanak Prasekolah, Pyrimidine, Pyrimidine Metabolism, Budak sekolah, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Tan, E H; Razak, S A; Abdullah, J M; Yusoff, Mohamed A A

De-novo mutations and genetic variation in the SCN1A gene in Malaysian patients with generalized epilepsy with febrile seizures plus (GEFS+) Artikel Jurnal

Epilepsy Research, 102 (3), hlm. 210-215, 2012, ISSN: 09201211, (dipetik oleh 2).

Abstrak | Pautan | BibTeX | Tag: Alanine, Amino Acid Substitution, Arginine, Artikel, Asparagine, Aspartic Acid, Anak-anak, Artikel Klinikal, Clinical Feature, Kajian Terkawal, Persatuan Penyakit, DNA Mutational Analysis, DNA Sequence, Elektroensefalografi, Epilepsi, Febrile, Febrile Convulsion, Perempuan, Gen, Gene Frequency, Pengenalan Gen, Generalized, Generalized Epilepsy, Persatuan Genetik, Kecenderungan Genetik, Genetic Screening, Genetic Variability, Glycine, Histidine, Manusia, Bayi, Malaysia, Lelaki, Missense Mutation, Molecular Pathology, Mutation, Mutational Analysis, Mutator Gene, Nav1.1 Voltage-Gated Sodium Channel, Onset Age, Patient Assessment, Polimorfisme, Kanak-kanak Prasekolah, Jurnal Keutamaan, Promoter Region, Budak sekolah, Seizure, Sequence Analysis, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal, Sodium Channel Nav1.1, Voltage Gated Sodium Channel Alpha1 Subunit Gene

@artikel{Tan2012210,
tajuk = {De-novo mutations and genetic variation in the SCN1A gene in Malaysian patients with generalized epilepsy with febrile seizures plus (GEFS+)},
pengarang = {E H Tan and S A Razak and J M Abdullah and A A Mohamed Yusoff},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870296042&doi=10.1016%2fj.eplepsyres.2012.08.004&rakan kongsi = 40&md5=25cc4eeb07db2492a7c04c6b3b3b2167},
doi = {10.1016/j.eplepsyres.2012.08.004},
terbitan = {09201211},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Epilepsy Research},
isi padu = {102},
nombor = {3},
halaman = {210-215},
abstrak = {Generalized epilepsy with febrile seizures plus (GEFS+) comprises a group of clinically and genetically heterogeneous epilepsy syndrome. Di sini, we provide the first report of clinical presentation and mutational analysis of SCN1A gene in 36 Malaysian GEFS+ patients. Mutational analysis of SCN1A gene revealed twenty seven sequence variants (missense mutation and silent polymorphism also intronic polymorphism), as well as 2 novel de-novo mutations were found in our patients at coding regions, c.5197A>G (N1733D) and c.4748A>G (H1583R). Our findings provide potential genetic insights into the pathogenesis of GEFS+ in Malaysian populations concerning the SCN1A gene mutations. © 2012 Elsevier B.V.},
nota = {dipetik oleh 2},
kata kunci = {Alanine, Amino Acid Substitution, Arginine, Artikel, Asparagine, Aspartic Acid, Anak-anak, Artikel Klinikal, Clinical Feature, Kajian Terkawal, Persatuan Penyakit, DNA Mutational Analysis, DNA Sequence, Elektroensefalografi, Epilepsi, Febrile, Febrile Convulsion, Perempuan, Gen, Gene Frequency, Pengenalan Gen, Generalized, Generalized Epilepsy, Persatuan Genetik, Kecenderungan Genetik, Genetic Screening, Genetic Variability, Glycine, Histidine, Manusia, Bayi, Malaysia, Lelaki, Missense Mutation, Molecular Pathology, Mutation, Mutational Analysis, Mutator Gene, Nav1.1 Voltage-Gated Sodium Channel, Onset Age, Patient Assessment, Polimorfisme, Kanak-kanak Prasekolah, Jurnal Keutamaan, Promoter Region, Budak sekolah, Seizure, Sequence Analysis, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal, Sodium Channel Nav1.1, Voltage Gated Sodium Channel Alpha1 Subunit Gene},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Salih, M R M; Laut, M B; Hassali, M A A; Shafie, A A; Al-Lela, Wahai Q B; Abd, Ke dan; Ganesan, V M

Characteristics of seizure frequency among Malaysian children diagnosed with structural-metabolic epilepsy Artikel Jurnal

Journal of Neurosciences in Rural Practice, 3 (3), hlm. 244-250, 2012, ISSN: 09763147, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: Remaja, Anticonvulsive Agent, Artikel, Autisme, Benign Childhood Epilepsy, Brain Disease, Carbamazepine, Cerebral Palsy, Anak-anak, Chinese, Clonazepam, Analisis Kohort, Congenital Toxoplasmosis, Kajian Terkawal, Corpus Callosum Agenesis, Dandy Walker Syndrome, Degenerative Disease, Gangguan Perkembangan, Disorders of Mitochondrial Functions, Sindrom Down, Epilepsi, Etnik, Etiracetam, Perempuan, Focal Epilepsy, Happy Puppet Syndrome, Manusia, Hydrocephalus, Orang India, Kemerosotan Intelektual, Lamotrigine, Kajian Klinikal Utama, Malay, Lelaki, Medical Record, Microcephaly, Monotherapy, Kanak-kanak Prasekolah, Jurnal Keutamaan, Kajian Retrospektif, Budak sekolah, Seizure, Structural Metabolic Epilepsy, Tuberous Sclerosis, Valproic Acid, Wilson Disease

@artikel{Salih2012244,
tajuk = {Characteristics of seizure frequency among Malaysian children diagnosed with structural-metabolic epilepsy},
pengarang = {M R M Salih and M B Bahari and M A A Hassali and A A Shafie and O Q B Al-Lela and A Y Abd and V M Ganesan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870233746&doi=10.4103%2f0976-3147.102596&rakan kongsi = 40&md5=039bd22d6c38366ebfdd00a4254c20f0},
doi = {10.4103/0976-3147.102596},
terbitan = {09763147},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Journal of Neurosciences in Rural Practice},
isi padu = {3},
nombor = {3},
halaman = {244-250},
abstrak = {Pengenalan: Seizure-free patients or substantial reduction in seizure frequency are the most important outcome measures in the management of epilepsy. The study aimed to evaluate the patterns of seizure frequency and its relationship with demographics, clinical characteristics, and outcomes. Materials and Methods: A retrospective cohort study was conducted at the Pediatric Neurology Clinic, Hospital Pulau Pinang. Over a period of 6 bulan, the required data were extracted from the medical records using a pre-designed data collection form. Keputusan: Seizure frequency showed no significant association with patient's demographics and clinical characteristic. Walau bagaimanapun, significant reduction in seizure frequency from the baseline to the last follow-up visit was only seen in certain subgroups of patients including Malays, perempuan, patients <4 years of age, patients with global developmental delay/intellectual disability, and patients with focal seizure. There was no significant association between seizure frequency and rate of adverse events. Polytherapy visits were associated with higher seizure frequency than monotherapy visits (27.97 ± 56.66, 10.94 ± 30.96 attack per month, respectively) (P < 0.001). There was a clear tendency to get antiepileptic drugs used at doses above the recommended range in polytherapy (8.4%) rather than in monotherapy (1.4%) visits (P < 0.001). A significant correlation was found between seizure frequency and number of visits per patient per year (r = 0.450, P < 0.001). Conclusion: Among children with structural-metabolic epilepsy, Malays, females, patients <4 years of age, patients with global developmental delay/intellectual disability and patients manifested with focal seizure are more responsive antiepileptic drug therapy than the other subgroups of patients.},
nota = {dipetik oleh 1},
kata kunci = {Remaja, Anticonvulsive Agent, Artikel, Autisme, Benign Childhood Epilepsy, Brain Disease, Carbamazepine, Cerebral Palsy, Anak-anak, Chinese, Clonazepam, Analisis Kohort, Congenital Toxoplasmosis, Kajian Terkawal, Corpus Callosum Agenesis, Dandy Walker Syndrome, Degenerative Disease, Gangguan Perkembangan, Disorders of Mitochondrial Functions, Sindrom Down, Epilepsi, Etnik, Etiracetam, Perempuan, Focal Epilepsy, Happy Puppet Syndrome, Manusia, Hydrocephalus, Orang India, Kemerosotan Intelektual, Lamotrigine, Kajian Klinikal Utama, Malay, Lelaki, Medical Record, Microcephaly, Monotherapy, Kanak-kanak Prasekolah, Jurnal Keutamaan, Kajian Retrospektif, Budak sekolah, Seizure, Structural Metabolic Epilepsy, Tuberous Sclerosis, Valproic Acid, Wilson Disease},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Clark, M; Coklat, R; Karrapaya, R

Pandangan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi kanak-kanak kurang upaya Artikel Jurnal

Jurnal Penyelidikan Kecacatan Intelektual, 56 (1), hlm. 45-60, 2012, ISSN: 09642633, (dipetik oleh 16).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Autisme, Pengasuh, Cerebral Palsy, Anak-anak, Kos Penyakit, Perbandingan Merentas Budaya, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Kanak-kanak Kurang Upaya, Sindrom Down, Keluarga, Kesihatan Keluarga, Perempuan, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Tinjauan Kesihatan, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kepuasan Hidup, Malaysia, Lelaki, Ibu bapa, Dasar, Prasekolah, Kanak-kanak Prasekolah, Psikometrik, Kualiti hidup, Soal selidik, Budak sekolah, Sokongan Sosial, Faktor Sosioekonomi

@artikel{Clark201245,
tajuk = {Pandangan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi kanak-kanak kurang upaya},
pengarang = {M Clark dan R Brown dan R Karrapaya},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-83855165819&doi=10.1111/j.1365-2788.2011.01408.x&rakan kongsi = 40&md5 = 4822406179501d1b0b93c5374e383637},
doi = {10.1111/j.1365-2788.2011.01408.x},
terbitan = {09642633},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Jurnal Penyelidikan Kecacatan Intelektual},
isi padu = {56},
nombor = {1},
halaman = {45-60},
abstrak = {Latar Belakang Walaupun terdapat banyak literatur dalam kualiti hidup keluarga yang merangkumi anak-anak kurang upaya, majoriti penyelidikan telah dilakukan di negara-negara barat. Kajian ini memberikan penerokaan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi anak-anak yang kurang upaya perkembangan / intelektual. Dinamika yang mencirikan masyarakat Malaysia digambarkan sebagai perkembangan dalam dasar sosial dan penyediaan perkhidmatan yang menyokong orang kurang upaya dan keluarga mereka. Data Kaedah Soal Selidik dikumpulkan menggunakan Tinjauan Kualiti Hidup Keluarga - Versi pendek. Anggota 52 keluarga yang merangkumi satu atau dua kanak-kanak kurang upaya ditemu ramah. Respons mereka memberikan persepsi mereka dalam enam dimensi kualiti hidup keluarga di sembilan domain kehidupan yang dinilai. Hasil Dapatan menunjukkan corak penilaian 'penting' yang dirasakan kuat pada setiap domain kehidupan berbanding dengan penilaian min untuk dimensi kualiti hidup keluarga yang lain. Beberapa dimensi kualiti hidup keluarga, khususnya 'peluang', ínitiative 'dan áttainment', menunjukkan hubungan yang sangat kuat antara satu sama lain. Keseluruhan cara kepuasan dengan dan pencapaian kualiti hidup keluarga serta penilaian global terhadap kualiti hidup dan kepuasan semua menunjukkan hubungan yang signifikan, walaupun setiap korelasi ini menyumbang kurang daripada 50% dari varians biasa. Kesimpulan Peringkat kepentingan dapat dilihat sebagai faktor penentu dari segi kualiti hidup, dan memainkan peranan penting dalam menyokong pencapaian, dan kepuasan dengan, kualiti hidup keluarga, menanggung peluang, inisiatif dan kestabilan mencukupi. Keperluan untuk sampel yang lebih luas termasuk keluarga yang tidak menerima perkhidmatan diperhatikan. Soalan penyelidikan masa depan berdasarkan hasil kajian semasa dan beberapa dinamika yang mempengaruhi masyarakat Malaysia juga dicadangkan. © 2011 Penulis. Jurnal Penyelidikan Kecacatan Intelektual © 2011 Blackwell Publishing Ltd.},
nota = {dipetik oleh 16},
kata kunci = {Remaja, Dewasa, Artikel, Autisme, Pengasuh, Cerebral Palsy, Anak-anak, Kos Penyakit, Perbandingan Merentas Budaya, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Kanak-kanak Kurang Upaya, Sindrom Down, Keluarga, Kesihatan Keluarga, Perempuan, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Tinjauan Kesihatan, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kepuasan Hidup, Malaysia, Lelaki, Ibu bapa, Dasar, Prasekolah, Kanak-kanak Prasekolah, Psikometrik, Kualiti hidup, Soal selidik, Budak sekolah, Sokongan Sosial, Faktor Sosioekonomi},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Latar Belakang Walaupun terdapat banyak literatur dalam kualiti hidup keluarga yang merangkumi anak-anak kurang upaya, majoriti penyelidikan telah dilakukan di negara-negara barat. Kajian ini memberikan penerokaan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi anak-anak yang kurang upaya perkembangan / intelektual. Dinamika yang mencirikan masyarakat Malaysia digambarkan sebagai perkembangan dalam dasar sosial dan penyediaan perkhidmatan yang menyokong orang kurang upaya dan keluarga mereka. Data Kaedah Soal Selidik dikumpulkan menggunakan Tinjauan Kualiti Hidup Keluarga - Versi pendek. Anggota 52 keluarga yang merangkumi satu atau dua kanak-kanak kurang upaya ditemu ramah. Respons mereka memberikan persepsi mereka dalam enam dimensi kualiti hidup keluarga di sembilan domain kehidupan yang dinilai. Hasil Dapatan menunjukkan corak penilaian 'penting' yang dirasakan kuat pada setiap domain kehidupan berbanding dengan penilaian min untuk dimensi kualiti hidup keluarga yang lain. Beberapa dimensi kualiti hidup keluarga, khususnya 'peluang', ínitiative 'dan áttainment', menunjukkan hubungan yang sangat kuat antara satu sama lain. Keseluruhan cara kepuasan dengan dan pencapaian kualiti hidup keluarga serta penilaian global terhadap kualiti hidup dan kepuasan semua menunjukkan hubungan yang signifikan, walaupun setiap korelasi ini menyumbang kurang daripada 50% dari varians biasa. Kesimpulan Peringkat kepentingan dapat dilihat sebagai faktor penentu dari segi kualiti hidup, dan memainkan peranan penting dalam menyokong pencapaian, dan kepuasan dengan, kualiti hidup keluarga, menanggung peluang, inisiatif dan kestabilan mencukupi. Keperluan untuk sampel yang lebih luas termasuk keluarga yang tidak menerima perkhidmatan diperhatikan. Soalan penyelidikan masa depan berdasarkan hasil kajian semasa dan beberapa dinamika yang mempengaruhi masyarakat Malaysia juga dicadangkan. © 2011 Penulis. Jurnal Penyelidikan Kecacatan Intelektual © 2011 Blackwell Publishing Ltd.

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