Senarai Penerbitan
Terdapat sebilangan besar penyelidikan berkaitan autisme yang boleh dijumpai di Malaysia yang umumnya menumpukan pada ASD, gangguan pembelajaran, alat bantu komunikasi, terapi dan banyak lagi. Senarai penerbitan disediakan di bawah:
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2020 |
Leong, D; Hedley, D; Uljarevic, M Poh-tay-toe, Poh-tah-toe: Diagnosis dan Konseptualisasi Autisme Artikel Jurnal Jurnal Neurologi Kanak-kanak, 35 (3), hlm. 247-248, 2020, ISSN: 08830738, (dipetik oleh 0). Pautan | BibTeX | Tag: Keresahan, Gangguan Defisit Perhatian, Autisme, Pengasuh, Anak-anak, Artikel Klinikal, Amalan Klinikal, Kelakuan Mengganggu, DSM-5, Susulan, Manusia, Gangguan Pembelajaran, Surat, Kesihatan mental, Gangguan Mood, Pasukan Pelbagai Disiplin, Neuropsychiatry, Jurnal Keutamaan, Pengangguran, Tenaga kerja @artikel{Leong2020247, tajuk = {Poh-tay-toe, Poh-tah-toe: Diagnosis dan Konseptualisasi Autisme}, pengarang = {D Leong dan D Hedley dan M Uljarević}, url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-85078570091&doi = 10.1177% 2f0883073819887587&rakan kongsi = 40&md5 = f40e68dc7723d94e6c9dfeb9820558a4}, doi = {10.1177/0883073819887587}, terbitan = {08830738}, tahun = {2020}, tarikh = {2020-01-01}, jurnal = {Jurnal Neurologi Kanak-kanak}, isi padu = {35}, nombor = {3}, halaman = {247-248}, penerbit = {SAGE Publications Inc.}, nota = {dipetik oleh 0}, kata kunci = {Keresahan, Gangguan Defisit Perhatian, Autisme, Pengasuh, Anak-anak, Artikel Klinikal, Amalan Klinikal, Kelakuan Mengganggu, DSM-5, Susulan, Manusia, Gangguan Pembelajaran, Surat, Kesihatan mental, Gangguan Mood, Pasukan Pelbagai Disiplin, Neuropsychiatry, Jurnal Keutamaan, Pengangguran, Tenaga kerja}, pubstate = {diterbitkan}, tppubtype = {artikel} } |
2019 |
Liu, Y-W; Liong, M T; Am, Y -C E; Huang, H -Y; Peng, W -S; Cheng, Y -F; Lin, Y -S; Wu, Y-Y; Tsai, Y -C Nutrien, 11 (4), 2019, ISSN: 20726643, (dipetik oleh 4). Abstrak | Pautan | BibTeX | Tag: Senarai Semak Tingkah Laku Aberrant versi Taiwan, Remaja, umur, Faktor Umur, Keagresifan, Keresahan, Artikel, Gangguan Defisit Perhatian, Autisme, Senarai Semak Tingkah Laku Autisme, Temuduga Diagnostik Autisme Disemak, Gangguan Spektrum Autisme, Tingkah Laku Kanak-kanak, Senarai Semak Tingkah Laku Kanak-kanak, Anak-anak, Skala Teraan Global Klinikal, Gangguan Komunikasi, Kajian Terkawal, Prosedur Double Blind, Kaedah Double-Blind, Perempuan, Gangguan Kebimbangan Umum, Manusia, Impulsif, Lactobacillus delbrueckii, Lelaki, Fisiologi, Placebo, Placebo, Gangguan Tekanan Selepas Traumatik, Agen Probiotik, Probiotik, Psikologi, Soal selidik, Percubaan Terkawal Rawak, Skala penilaian, Budak sekolah, Sistem Pemarkahan, Kelakuan Sosial, Interaksi Sosial, Masalah Sosial, Skala Responsif Sosial, Tinjauan, Penilaian Swanson Nolan dan Pelham IV, Protein Berkaitan Sinaptosomal 23, Taiwan @artikel{Liu2019, tajuk = {Kesan lactobacillus plantarum PS128 pada kanak-kanak dengan gangguan spektrum autisme di Taiwan: A rawak, buta dua, percubaan terkawal plasebo}, pengarang = {Y -W Liu dan M T Liong dan Y -C E Chung dan H -Y Huang dan W -S Peng dan Y -F Cheng dan Y -S Lin dan Y -Y Wu dan Y -C Tsai}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064817846&doi=10.3390/nu11040820&rakan kongsi = 40&md5=ca04462e8710198b821b44f8e73061f3}, doi = {10.3390/nu11040820}, terbitan = {20726643}, tahun = {2019}, tarikh = {2019-01-01}, jurnal = {Nutrien}, isi padu = {11}, nombor = {4}, penerbit = {MDPI AG}, abstrak = {Empat minggu ini, rawak, buta dua, kajian terkawal plasebo menyiasat kesan Lactobacillus plantarum PS128 (PS128) pada kanak-kanak lelaki dengan gangguan spektrum autisme (ASD) berumur 7-15 di Taiwan. Semua subjek memenuhi kriteria untuk diagnosis ASD DSM-V dan Temuduga Diagnostik Autisme-Disemak (ADI-R). Soal selidik yang digunakan untuk ukuran hasil utama termasuk versi Senarai Semak Tingkah Laku Autisme-Taiwan (ABC-T), Skala Responsif Sosial (SRS) dan Senarai Semak Tingkah Laku Kanak-kanak (CBCL). Swanson, Nolan, dan versi Pelham-IV-Taiwan (SNAP-IV) dan Penambahbaikan Tera Global Klinikal (CGI-I) digunakan untuk ukuran hasil sekunder. Keputusan menunjukkan bahawa PS128 memperbaiki tingkah laku pembangkang/menentang, dan bahawa jumlah skor SNAP-IV untuk kanak-kanak yang lebih muda (berumur 7−12) meningkat dengan ketara berbanding dengan kumpulan plasebo. Selain itu, beberapa elemen juga telah dipertingkatkan dengan ketara dalam kumpulan PS128 selepas penggunaan PS128 selama 28 hari. Kajian lanjut diperlukan untuk menjelaskan dengan lebih baik kesan PS128 untuk kanak-kanak yang lebih muda dengan ASD pada gejala yang lebih luas. © 2019 oleh pengarang. MDPI pemegang lesen, Basel, Switzerland.}, nota = {dipetik oleh 4}, kata kunci = {Senarai Semak Tingkah Laku Aberrant versi Taiwan, Remaja, umur, Faktor Umur, Keagresifan, Keresahan, Artikel, Gangguan Defisit Perhatian, Autisme, Senarai Semak Tingkah Laku Autisme, Temuduga Diagnostik Autisme Disemak, Gangguan Spektrum Autisme, Tingkah Laku Kanak-kanak, Senarai Semak Tingkah Laku Kanak-kanak, Anak-anak, Skala Teraan Global Klinikal, Gangguan Komunikasi, Kajian Terkawal, Prosedur Double Blind, Kaedah Double-Blind, Perempuan, Gangguan Kebimbangan Umum, Manusia, Impulsif, Lactobacillus delbrueckii, Lelaki, Fisiologi, Placebo, Placebo, Gangguan Tekanan Selepas Traumatik, Agen Probiotik, Probiotik, Psikologi, Soal selidik, Percubaan Terkawal Rawak, Skala penilaian, Budak sekolah, Sistem Pemarkahan, Kelakuan Sosial, Interaksi Sosial, Masalah Sosial, Skala Responsif Sosial, Tinjauan, Penilaian Swanson Nolan dan Pelham IV, Protein Berkaitan Sinaptosomal 23, Taiwan}, pubstate = {diterbitkan}, tppubtype = {artikel} } Empat minggu ini, rawak, buta dua, kajian terkawal plasebo menyiasat kesan Lactobacillus plantarum PS128 (PS128) pada kanak-kanak lelaki dengan gangguan spektrum autisme (ASD) berumur 7-15 di Taiwan. Semua subjek memenuhi kriteria untuk diagnosis ASD DSM-V dan Temuduga Diagnostik Autisme-Disemak (ADI-R). Soal selidik yang digunakan untuk ukuran hasil utama termasuk versi Senarai Semak Tingkah Laku Autisme-Taiwan (ABC-T), Skala Responsif Sosial (SRS) dan Senarai Semak Tingkah Laku Kanak-kanak (CBCL). Swanson, Nolan, dan versi Pelham-IV-Taiwan (SNAP-IV) dan Penambahbaikan Tera Global Klinikal (CGI-I) digunakan untuk ukuran hasil sekunder. Keputusan menunjukkan bahawa PS128 memperbaiki tingkah laku pembangkang/menentang, dan bahawa jumlah skor SNAP-IV untuk kanak-kanak yang lebih muda (berumur 7−12) meningkat dengan ketara berbanding dengan kumpulan plasebo. Selain itu, beberapa elemen juga telah dipertingkatkan dengan ketara dalam kumpulan PS128 selepas penggunaan PS128 selama 28 hari. Kajian lanjut diperlukan untuk menjelaskan dengan lebih baik kesan PS128 untuk kanak-kanak yang lebih muda dengan ASD pada gejala yang lebih luas. © 2019 oleh pengarang. MDPI pemegang lesen, Basel, Switzerland. |
2018 |
Tsuchida, N; Hamada, K; Shiina, M; Kato, M; Kobayashi, Y; Tohyama, J; Kimura, K; Hoshino, K; Ganesan, V; Teik, K W; Nakashima, M; Mitsuhashi, S; Mizuguchi, T; Takata, A; Miyake, N; Saitsu, H; Ogata, K; Miyatake, S; Matsumoto, N GRIN2D variants in three cases of developmental and epileptic encephalopathy Artikel Jurnal Clinical Genetics, 94 (6), hlm. 538-547, 2018, ISSN: 00099163, (dipetik oleh 4). Abstrak | Pautan | BibTeX | Tag: Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing @artikel{Tsuchida2018538, tajuk = {GRIN2D variants in three cases of developmental and epileptic encephalopathy}, pengarang = {N Tsuchida and K Hamada and M Shiina and M Kato and Y Kobayashi and J Tohyama and K Kimura and K Hoshino and V Ganesan and K W Teik and M Nakashima and S Mitsuhashi and T Mizuguchi and A Takata and N Miyake and H Saitsu and K Ogata and S Miyatake and N Matsumoto}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056487337&doi=10.1111%2fcge.13454&rakan kongsi = 40&md5=f0d32670db57261820bc244943cffd62}, doi = {10.1111/cge.13454}, terbitan = {00099163}, tahun = {2018}, tarikh = {2018-01-01}, jurnal = {Clinical Genetics}, isi padu = {94}, nombor = {6}, halaman = {538-547}, penerbit = {Blackwell Publishing Ltd}, abstrak = {N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Baru-baru ini, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. Dalam kajian ini, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd}, nota = {dipetik oleh 4}, kata kunci = {Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing}, pubstate = {diterbitkan}, tppubtype = {artikel} } N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Baru-baru ini, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. Dalam kajian ini, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd |
Diurut, R Autisme dan trikotilomania dalam remaja lelaki Artikel Jurnal Laporan Kes BMJ, 2018 , 2018, ISSN: 1757790X, (dipetik oleh 0). Abstrak | Pautan | BibTeX | Tag: Remaja, Alopecia, Keresahan, Artikel, Gangguan Defisit Perhatian, Gangguan Hiperaktifan Kekurangan Perhatian, Autisme, Gangguan Spektrum Autisme, Gangguan Tingkah Laku, Berat badan, Laporan kes, Perangsang Sistem Saraf Pusat, Senarai Semak Tingkah Laku Kanak-kanak, Artikel Klinikal, komorbiditi, Komplikasi, Diagnosis, Berbeza, Diagnosis pembezaan, Pentitratan Dos Ubat, Toleransi Dadah, DSM-5, Echolalia, Fluvoxamine, Susulan, Manusia, Hiperaktif, Kemerosotan Intelektual, Lelaki, Metilfenidat, Obesiti, Terapi pekerjaan, Indeks Penaakulan Persepsi, Jurnal Keutamaan, Indeks Kelajuan Pemprosesan, Skala Penarafan Status Psikiatri, Skala Penarafan Psikologi, Skala penilaian, Kegelisahan, Ganjaran, Perencat Serapan Serotonin, Perencat Serapan Serotonin, Pendidikan Khas, Kelewatan Pertuturan, Gangguan Pertuturan, Terapi ucapan, Trikotilomania, Indeks Kefahaman Lisan, Skala Kepintaran Wechsler, Indeks Memori Bekerja @artikel{Masiran2018b, tajuk = {Autisme dan trikotilomania dalam remaja lelaki}, pengarang = {R Diurut}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053164449&doi = 10.1136% 2fbcr-2018-226270&rakan kongsi = 40&md5=7eed3f6af717df527dce73838feab571}, doi = {10.1136/bcr-2018-226270}, terbitan = {1757790X}, tahun = {2018}, tarikh = {2018-01-01}, jurnal = {Laporan Kes BMJ}, isi padu = {2018}, penerbit = {Kumpulan Penerbitan BMJ}, abstrak = {Remaja yang mengalami gangguan spektrum autisme dan gangguan hiperaktif kekurangan perhatian yang tidak dirawat dengan betul ditunjukkan dengan tarikan rambut berulang. Rawatan dengan perencat pengambilan semula serotonin terpilih dan perangsang memperbaiki keadaan ini. © © BMJ Publishing Group Limited 2018.}, nota = {dipetik oleh 0}, kata kunci = {Remaja, Alopecia, Keresahan, Artikel, Gangguan Defisit Perhatian, Gangguan Hiperaktifan Kekurangan Perhatian, Autisme, Gangguan Spektrum Autisme, Gangguan Tingkah Laku, Berat badan, Laporan kes, Perangsang Sistem Saraf Pusat, Senarai Semak Tingkah Laku Kanak-kanak, Artikel Klinikal, komorbiditi, Komplikasi, Diagnosis, Berbeza, Diagnosis pembezaan, Pentitratan Dos Ubat, Toleransi Dadah, DSM-5, Echolalia, Fluvoxamine, Susulan, Manusia, Hiperaktif, Kemerosotan Intelektual, Lelaki, Metilfenidat, Obesiti, Terapi pekerjaan, Indeks Penaakulan Persepsi, Jurnal Keutamaan, Indeks Kelajuan Pemprosesan, Skala Penarafan Status Psikiatri, Skala Penarafan Psikologi, Skala penilaian, Kegelisahan, Ganjaran, Perencat Serapan Serotonin, Perencat Serapan Serotonin, Pendidikan Khas, Kelewatan Pertuturan, Gangguan Pertuturan, Terapi ucapan, Trikotilomania, Indeks Kefahaman Lisan, Skala Kepintaran Wechsler, Indeks Memori Bekerja}, pubstate = {diterbitkan}, tppubtype = {artikel} } Remaja yang mengalami gangguan spektrum autisme dan gangguan hiperaktif kekurangan perhatian yang tidak dirawat dengan betul ditunjukkan dengan tarikan rambut berulang. Rawatan dengan perencat pengambilan semula serotonin terpilih dan perangsang memperbaiki keadaan ini. © © BMJ Publishing Group Limited 2018. |
2017 |
Charara, R; Forouzanfar, M; Naghavi, M; Moradi-Lakeh, M; Afshin, A; Anda, T; Daoud, F; Wang, H; Bcheraoui, TERDAPAT; Khalil, Saya; Hamadeh, R R; Khosravi, A; Rahimi-Movaghar, V; Khader, Y; Al-Hamad, N; Obermeyer, C M; Rafay, A; Asghar, R; Rana, S M; Shaheen, A; Abu-Rmeileh, N M E; Husseini, A; Abu-Raddad, L J; Khoja, T; Rayess, Z A A; AlBuhairan, F S; Hsairi, M; Alomari, M A; Tetapi, R; Roshandel, G; Terkawi, A S; Hamidi, S; Refaat, A H; Westerman, R; Kiadaliri, A A; Akanda, A S; Tetapi, S D; Bacha, U; Badawi, A; Bazargan-Hejazi, S; Faghmous, Saya A D; Fereshtehnejad, S -M; Fischer, F; Jonas, J B; Lalai, B K; Mehari, A; Omer, S B; Pourmalek, F; Uthman, Wahai A; Mokdad, A A; Maalouf, F T; Abd-Allah, F; Akseer, N; Arya, D; Borschmann, R; Brazinova, A; Brugha, T S; Catala-Lopez, F; Degenhardt, L; Ferrari, A; Haro, J M; Horino, M; Hornberger, J C; Huang, H; Kieling, C; Kim, D; Kim, Y; Knudsen, Seorang K; Mitchell, P B; Patton, G; Sagar, R; Satpati, M; Savuon, K; Seedat, S; Shiue, Saya; Hutan, J C; Stein, D J; Tabb, K M; Whiteford, H A; Yip, P; Yonemoto, N; Murray, C J L; Mokdad, A H The burden of mental disorders in the eastern mediterranean region, 1990-2013 Artikel Jurnal PLoS SATU, 12 (1), 2017, ISSN: 19326203, (dipetik oleh 30). Abstrak | Pautan | BibTeX | Tag: 80 and Over, Remaja, Dewasa, umur, Faktor Umur, Aged, Anxiety Disorder, Artikel, Gangguan Defisit Perhatian, Autisme, Bipolar Disorder, Anak-anak, Conduct Disorder, Kemurungan, Elderly People, Perempuan, Global Health, Groups by Age, Status kesihatan, Highest Income Group, Manusia, Bayi, Kemerosotan Intelektual, Kuwait, Life Expectancy, Kajian Klinikal Utama, Lelaki, Mediterranean Region, Mental Disease, Gangguan Mental, Kesihatan mental, Perkhidmatan Kesihatan Mental, Pertengahan umur, Middle Income Group, Mortality, Baru lahir, Palestine, Premature Mortality, Prasekolah, Kanak-kanak Prasekolah, Kelaziman, Qatar, Quality Adjusted Life Year, Skizofrenia, Sex Difference, Faktor Seks, Southern Europe, Time Factor, Time Factors, United Arab Emirates, Dewasa Muda @artikel{Charara2017, tajuk = {The burden of mental disorders in the eastern mediterranean region, 1990-2013}, pengarang = {R Charara and M Forouzanfar and M Naghavi and M Moradi-Lakeh and A Afshin and T Vos and F Daoud and H Wang and C E Bcheraoui and I Khalil and R R Hamadeh and A Khosravi and V Rahimi-Movaghar and Y Khader and N Al-Hamad and C M Obermeyer and A Rafay and R Asghar and S M Rana and A Shaheen and N M E Abu-Rmeileh and A Husseini and L J Abu-Raddad and T Khoja and Z A A Rayess and F S AlBuhairan and M Hsairi and M A Alomari and R Ali and G Roshandel and A S Terkawi and S Hamidi and A H Refaat and R Westerman and A A Kiadaliri and A S Akanda and S D Ali and U Bacha and A Badawi and S Bazargan-Hejazi and I A D Faghmous and S -M Fereshtehnejad and F Fischer and J B Jonas and B K Defo and A Mehari and S B Omer and F Pourmalek and O A Uthman and A A Mokdad and F T Maalouf and F Abd-Allah and N Akseer and D Arya and R Borschmann and A Brazinova and T S Brugha and F Catala-Lopez and L Degenhardt and A Ferrari and J M Haro and M Horino and J C Hornberger and H Huang and C Kieling and D Kim and Y Kim and A K Knudsen and P B Mitchell and G Patton and R Sagar and M Satpathy and K Savuon and S Seedat and I Shiue and J C Skogen and D J Stein and K M Tabb and H A Whiteford and P Yip and N Yonemoto and C J L Murray and A H Mokdad}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009892168&doi=10.1371/journal.pone.0169575&rakan kongsi = 40&md5=471830ec1239e37c6fc4681bed5698f6}, doi = {10.1371/jurnal.pone.0169575}, terbitan = {19326203}, tahun = {2017}, tarikh = {2017-01-01}, jurnal = {PLoS SATU}, isi padu = {12}, nombor = {1}, penerbit = {Perpustakaan Awam Sains}, abstrak = {The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost-YLLs) and nonfatal outcomes (years lived with disability-YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. Dalam 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 jantan, 2426/100,000 perempuan) in high-income countries, 1884 DALYS/100,000 (1618/100,000 jantan, 2157/100,000 perempuan) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 jantan, 1717/100,000 perempuan) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25-49 age group, with a peak in the 35-39 years age group (5344 DALYs/100,000). The burden of mental disorders Burden of Mental Disorders in EMR PLOS ONE in EMR increased from 1726 DALYs/100,000 in 1990 ke 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Lebih-lebih lagi, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Sesungguhnya, mental health problems, if not properly addressed, will lead to an increased burden of diseases in the region. © 2017 Charara et al. Ini ialah artikel akses terbuka yang diedarkan di bawah syarat Lesen Atribusi Creative Commons, yang membenarkan penggunaan tanpa had, pengedaran, dan pembiakan dalam mana-mana medium, dengan syarat penulis dan sumber asal dikreditkan.}, nota = {dipetik oleh 30}, kata kunci = {80 and Over, Remaja, Dewasa, umur, Faktor Umur, Aged, Anxiety Disorder, Artikel, Gangguan Defisit Perhatian, Autisme, Bipolar Disorder, Anak-anak, Conduct Disorder, Kemurungan, Elderly People, Perempuan, Global Health, Groups by Age, Status kesihatan, Highest Income Group, Manusia, Bayi, Kemerosotan Intelektual, Kuwait, Life Expectancy, Kajian Klinikal Utama, Lelaki, Mediterranean Region, Mental Disease, Gangguan Mental, Kesihatan mental, Perkhidmatan Kesihatan Mental, Pertengahan umur, Middle Income Group, Mortality, Baru lahir, Palestine, Premature Mortality, Prasekolah, Kanak-kanak Prasekolah, Kelaziman, Qatar, Quality Adjusted Life Year, Skizofrenia, Sex Difference, Faktor Seks, Southern Europe, Time Factor, Time Factors, United Arab Emirates, Dewasa Muda}, pubstate = {diterbitkan}, tppubtype = {artikel} } The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost-YLLs) and nonfatal outcomes (years lived with disability-YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. Dalam 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 jantan, 2426/100,000 perempuan) in high-income countries, 1884 DALYS/100,000 (1618/100,000 jantan, 2157/100,000 perempuan) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 jantan, 1717/100,000 perempuan) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25-49 age group, with a peak in the 35-39 years age group (5344 DALYs/100,000). The burden of mental disorders Burden of Mental Disorders in EMR PLOS ONE in EMR increased from 1726 DALYs/100,000 in 1990 ke 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Lebih-lebih lagi, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Sesungguhnya, mental health problems, if not properly addressed, will lead to an increased burden of diseases in the region. © 2017 Charara et al. Ini ialah artikel akses terbuka yang diedarkan di bawah syarat Lesen Atribusi Creative Commons, yang membenarkan penggunaan tanpa had, pengedaran, dan pembiakan dalam mana-mana medium, dengan syarat penulis dan sumber asal dikreditkan. |
2016 |
Tan, M L; Ho, BUKAN PERKATAAN; Teh, K H Polyunsaturated fatty acids (PUFAs) for children with specific learning disorders Artikel Jurnal Pangkalan Data Cochrane dari Ulasan Sistematik, 2016 (9), 2016, ISSN: 1469493X, (dipetik oleh 6). Abstrak | Pautan | BibTeX | Tag: Gangguan Defisit Perhatian, Autisme, Carnosine, Anak-anak, Diet Supplementation, Drug Effect, Gastrointestinal Symptom, Manusia, Gangguan Pembelajaran, Meta Analysis, Penilaian Hasil, Placebo, Polyunsaturated Fatty Acid, Jurnal Keutamaan, Percubaan Terkawal Rawak, Kaji semula, Kajian Sistematik @artikel{Tan2016, tajuk = {Polyunsaturated fatty acids (PUFAs) for children with specific learning disorders}, pengarang = {M L Tan and J J Ho and K H Teh}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988922340&doi=10.1002%2f14651858.CD009398.pub3&rakan kongsi = 40&md5=3460f403b8829b4692a0b6f795f4a2a3}, doi = {10.1002/14651858.CD009398.pub3}, terbitan = {1469493X}, tahun = {2016}, tarikh = {2016-01-01}, jurnal = {Pangkalan Data Cochrane dari Ulasan Sistematik}, isi padu = {2016}, nombor = {9}, penerbit = {John Wiley and Sons Ltd}, abstrak = {Latar belakang: About 5% of school children have a specific learning disorder, defined as unexpected failure to acquire adequate abilities in reading, writing or mathematics that is not a result of reduced intellectual ability, inadequate teaching or social deprivation. Of these events, 80% are reading disorders. Polyunsaturated fatty acids (PUFAs), in particular, omega-3 and omega-6 fatty acids, which normally are abundant in the brain and in the retina, are important for learning. Some children with specific learning disorders have been found to be deficient in these PUFAs, and it is argued that supplementation of PUFAs may help these children improve their learning abilities. Objektif: 1. To assess effects on learning outcomes of supplementation of polyunsaturated fatty acids (PUFAs) for children with specific learning disorders.2. To determine whether adverse effects of supplementation of PUFAs are reported in these children. Search methods: In November 2015, we searched CENTRAL, Ovid MEDLINE, Embase, PsycINFO, 10 other databases and two trials registers. We also searched the reference lists of relevant articles. Selection criteria: Randomised controlled trials (RCTs) or quasi-RCTs comparing PUFAs with placebo or no treatment in children younger than 18 years with specific learning disabilities, as diagnosed in accordance with the fifth (or earlier) edition of theDiagnostic and Statistical Manual of Mental Disorders (DSM-5), or the 10th (or earlier) revision of the International Classification of Diseases (ICD-10) or equivalent criteria. We included children with coexisting developmental disorders such as attention deficit hyperactivity disorder (ADHD) or autism. Data collection and analysis: Two review authors (MLT and KHT) independently screened the titles and abstracts of articles identified by the search and eliminated all studies that did not meet the inclusion criteria. We contacted study authors to ask for missing information and clarification, when needed. We used the GRADE approach to assess the quality of evidence. Main results: Two small studies involving 116 kanak-kanak, mainly boys between 10 dan 18 years of age, met the inclusion criteria. One study was conducted in a school setting, the other at a specialised clinic. Both studies used three months of a combination of omega-3 and omega-6 supplements as the intervention compared with placebo. Although both studies had generally low risk of bias, we judged the risk of reporting bias as unclear in one study, and as high in the other study. Sebagai tambahan, one of the studies was funded by industry and reported active company involvement in the study. None of the studies reported data on the primary outcomes of reading, menulis, spelling and mathematics scores, as assessed by standardised tests. Evidence of low quality indicates that supplementation of PUFAs did not increase the risk of gastrointestinal disturbances (risk ratio 1.43, 95% confidence interval 0.25 ke 8.15; two studies, 116 kanak-kanak). Investigators reported no other adverse effects. Both studies reported attention deficit hyperactivity disorder (ADHD)-related behaviour outcomes. We were unable to combine the results in a meta-analysis because one study reported findings as a continuous outcome, and the other as a dichotomous outcome. No other secondary outcomes were reported. We excluded one study because it used a cointervention (carnosine), and five other studies because they did not provide a robust diagnosis of a specific learning disorder. We identified one ongoing study and found three studies awaiting classification. Authors' conclusions: Evidence is insufficient to permit any conclusions about the effect of PUFAs on the learning abilities of children with specific learning disorders. Well-designed RCTs with clearly defined populations of children with specific learning disorders who have been diagnosed by standardised diagnostic criteria are needed. © 2016 The Cochrane Collaboration.}, nota = {dipetik oleh 6}, kata kunci = {Gangguan Defisit Perhatian, Autisme, Carnosine, Anak-anak, Diet Supplementation, Drug Effect, Gastrointestinal Symptom, Manusia, Gangguan Pembelajaran, Meta Analysis, Penilaian Hasil, Placebo, Polyunsaturated Fatty Acid, Jurnal Keutamaan, Percubaan Terkawal Rawak, Kaji semula, Kajian Sistematik}, pubstate = {diterbitkan}, tppubtype = {artikel} } Latar belakang: About 5% of school children have a specific learning disorder, defined as unexpected failure to acquire adequate abilities in reading, writing or mathematics that is not a result of reduced intellectual ability, inadequate teaching or social deprivation. Of these events, 80% are reading disorders. Polyunsaturated fatty acids (PUFAs), in particular, omega-3 and omega-6 fatty acids, which normally are abundant in the brain and in the retina, are important for learning. Some children with specific learning disorders have been found to be deficient in these PUFAs, and it is argued that supplementation of PUFAs may help these children improve their learning abilities. Objektif: 1. To assess effects on learning outcomes of supplementation of polyunsaturated fatty acids (PUFAs) for children with specific learning disorders.2. To determine whether adverse effects of supplementation of PUFAs are reported in these children. Search methods: In November 2015, we searched CENTRAL, Ovid MEDLINE, Embase, PsycINFO, 10 other databases and two trials registers. We also searched the reference lists of relevant articles. Selection criteria: Randomised controlled trials (RCTs) or quasi-RCTs comparing PUFAs with placebo or no treatment in children younger than 18 years with specific learning disabilities, as diagnosed in accordance with the fifth (or earlier) edition of theDiagnostic and Statistical Manual of Mental Disorders (DSM-5), or the 10th (or earlier) revision of the International Classification of Diseases (ICD-10) or equivalent criteria. We included children with coexisting developmental disorders such as attention deficit hyperactivity disorder (ADHD) or autism. Data collection and analysis: Two review authors (MLT and KHT) independently screened the titles and abstracts of articles identified by the search and eliminated all studies that did not meet the inclusion criteria. We contacted study authors to ask for missing information and clarification, when needed. We used the GRADE approach to assess the quality of evidence. Main results: Two small studies involving 116 kanak-kanak, mainly boys between 10 dan 18 years of age, met the inclusion criteria. One study was conducted in a school setting, the other at a specialised clinic. Both studies used three months of a combination of omega-3 and omega-6 supplements as the intervention compared with placebo. Although both studies had generally low risk of bias, we judged the risk of reporting bias as unclear in one study, and as high in the other study. Sebagai tambahan, one of the studies was funded by industry and reported active company involvement in the study. None of the studies reported data on the primary outcomes of reading, menulis, spelling and mathematics scores, as assessed by standardised tests. Evidence of low quality indicates that supplementation of PUFAs did not increase the risk of gastrointestinal disturbances (risk ratio 1.43, 95% confidence interval 0.25 ke 8.15; two studies, 116 kanak-kanak). Investigators reported no other adverse effects. Both studies reported attention deficit hyperactivity disorder (ADHD)-related behaviour outcomes. We were unable to combine the results in a meta-analysis because one study reported findings as a continuous outcome, and the other as a dichotomous outcome. No other secondary outcomes were reported. We excluded one study because it used a cointervention (carnosine), and five other studies because they did not provide a robust diagnosis of a specific learning disorder. We identified one ongoing study and found three studies awaiting classification. Authors' conclusions: Evidence is insufficient to permit any conclusions about the effect of PUFAs on the learning abilities of children with specific learning disorders. Well-designed RCTs with clearly defined populations of children with specific learning disorders who have been diagnosed by standardised diagnostic criteria are needed. © 2016 The Cochrane Collaboration. |