@article{Rasool2014,
title = {Recent updates in the treatment of neurodegenerative disorders using natural compounds},
author = {M Rasool and A Malik and M S Qureshi and A Manan and P N Pushparaj and M Asif and M H Qazi and A M Qazi and M A Kamal and S H Gan and I A Sheikh},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901278946&doi=10.1155%2f2014%2f979730&partnerID=40&md5=c16e01bd0289ca547ae6afb7704ed5d6},
doi = {10.1155/2014/979730},
issn = {1741427X},
year = {2014},
date = {2014-01-01},
journal = {Evidence-based Complementary and Alternative Medicine},
volume = {2014},
publisher = {Oxford University Press},
abstract = {Neurodegenerative diseases are characterized by protein aggregates and inflammation as well as oxidative stress in the central nervous system (CNS). Multiple biological processes are linked to neurodegenerative diseases such as depletion or insufficient synthesis of neurotransmitters, oxidative stress, abnormal ubiquitination. Furthermore, damaging of blood brain barrier (BBB) in the CNS also leads to various CNS-related diseases. Even though synthetic drugs are used for the management of Alzheimer's disease, Parkinson's disease, autism, and many other chronic illnesses, they are not without side effects. The attentions of researchers have been inclined towards the phytochemicals, many of which have minimal side effects. Phytochemicals are promising therapeutic agents because many phytochemicals have anti-inflammatory, antioxidative as well as anticholinesterase activities. Various drugs of either synthetic or natural origin applied in the treatment of brain disorders need to cross the BBB before they can be used. This paper covers various researches related to phytochemicals used in the management of neurodegenerative disorders. © 2014 Mahmood Rasool et al.},
note = {cited By 49},
keywords = {Antiinflammatory Activity, Antioxidant Activity, Blood Brain Barrier, Cholinesterase, Degenerative Disease, Enzyme Inhibition, Human, Natural Product, Review},
pubstate = {published},
tppubtype = {article}
}