Testing - National Autism Resource Centre (NARC)

2014

Nor, Z M; Yusof, S N; Ghazi, H F; Isa, Z M

Does Bisphenol A contribute to autism spectrum disorder? Journal Article

Current Topics in Toxicology, 10 , pp. 63-70, 2014, ISSN: 09728228, (cited By 1).

Abstract | Links | BibTeX | Tags: 4' Isopropylidenediphenol, Article, Autism, Behaviour Change, Disease Association, Environmental Factor, First Pass Effect, Human, Population, Pregnancy, Prenatal Period

@article{Nor201463,
title = {Does Bisphenol A contribute to autism spectrum disorder?},
author = {Z M Nor and S N Yusof and H F Ghazi and Z M Isa},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939185210&partnerID=40&md5=57e7aabc3aa2ec1ab51747608ab6a9b2},
issn = {09728228},
year = {2014},
date = {2014-01-01},
journal = {Current Topics in Toxicology},
volume = {10},
pages = {63-70},
publisher = {Research Trends},
abstract = {Autism Spectrum Disorder (ASD) includes a range of conditions classified as neurodevelopmental disorders that have an onset from infancy. Multiple factors have been identified as causes for the autism spectrum disorder; however, the cascade of the disease is still not clearly defined. An increasing number of cases have been reported globally, for instance in US, UK, Canada and Australia. Environmental factors were suspected to be one of the causes. Bisphenol A (BPA) is an Endocrine Disruptor Compound (EDC) and used primarily as a monomer for the production of polycarbonate and epoxy resins, especially in feeding bottles for infants. Ongoing discussions are currently in progress on the reported low-dose effects of BPA, particularly its neurodevelopmental and behavioural effects. Many countries have banned the usage of BPA due to its harmful effects on children. This review aims at presenting an overview of the association between exposure to BPA and the neurobehavioural changes it triggers in children. Articles were obtained from the Science Direct and ProQuest search engines. The keywords used in the search were 'BPA' or 'bisphenol A' and áutism'. Fourty-seven articles were shortlisted, of which only five that fulfilled the requisite criteria were selected for review. All of them were cohort studies. Overall, an association has been established between prenatal and childhood exposure to BPA and neurobehavioural changes. The exposure during pregnancy was observed to have a greater impact on children. Earlier exposure during the prenatal period resulted in stronger associations. However, no association was found between BPA concentration of the child and neurobehavioural outcomes.},
note = {cited By 1},
keywords = {4' Isopropylidenediphenol, Article, Autism, Behaviour Change, Disease Association, Environmental Factor, First Pass Effect, Human, Population, Pregnancy, Prenatal Period},
pubstate = {published},
tppubtype = {article}
}

2012

Abdullah, M N; Mohamad, W M Z W; Abdullah, M R; Yaacob, M J; Baharuddin, M S

Perinatal, maternal and antenatal associated factors for autism: A case control study Conference

2012, ISBN: 9781467316668, (cited By 0).

Abstract | Links | BibTeX | Tags: Antenatal, ASD, Autism, Autistic, Biomedical Engineering, Case-Control Studies, Delivery, Diseases, Hospitals, Logistics, Maternal, Obstetrics, Parents, Perinatal, Pregnancy, Prenatal, Retrospective, Risk Factor

@conference{Abdullah2012144,
title = {Perinatal, maternal and antenatal associated factors for autism: A case control study},
author = {M N Abdullah and W M Z W Mohamad and M R Abdullah and M J Yaacob and M S Baharuddin},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876762294&doi=10.1109%2fIECBES.2012.6498121&partnerID=40&md5=b14466b2341cc29599332d94d866ea9a},
doi = {10.1109/IECBES.2012.6498121},
isbn = {9781467316668},
year = {2012},
date = {2012-01-01},
journal = {2012 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2012},
pages = {144-148},
abstract = {Autism disorders are a group of neurodevelopmental disorders which characterized into three main domains which are social interaction impairment, communication delay and repetitive or stereotypic behavior. Many studies had suggested that the risk factors for autism derive from three big factors namely environmental factors, genetic predisposition and vaccine induced. The aim of this study was to investigate the perinatal, maternal and antenatal associated factors on autistic disorder children at Hospital Pulau Pinang and Hospital Bukit Mertajam, Pulau Pinang. A case control study involving 312 cases and control was conducted using data retrieved from hospital records at Pulau Pinang hospital and Bukit Mertajam hospital from 2001 to 2008. The departments involved were Psychiatric, Obstetrics and Gynecology and Record and Management Department. All cases which met the inclusion and exclusion criteria were included in the study. Univariable and multivariable logistic regression were used to explore the perinatal, maternal and antenatal associated factors associated with autistic disorder children. There were seven associated factors contributed most to autistic disorder determination. The factors were maternal age [Adjusted Odds Ratio (OR): 1.41; 95% Confidence Interval (CI): (1.27, 1.57)], maternal smoking reported at first antenatal visit [Adjusted OR: 13.61; 95% CI: (1.87, 99.35)], birth asphyxia [Adjusted OR: 0.35; 95% CI: (0.11, 1.08)], psychiatric history [Adjusted OR: 54.94; 95% CI: (12.07, 250.04)], multiple gestation [Adjusted OR: 4.81; 95% CI: (1.86, 12.45)], parity for more than 4 [Adjusted OR: 0.11; 95% CI: (0.03, 0.47)], parity between 0 and 1 [Adjusted OR: 0.19; 95% CI: (0.07,0.55)], Chinese race compared to the Malay race [Adjusted OR: 10.11; 95% CI: (3.61, 28.30)] and Indian race compared to the Malay race [Adjusted OR: 5.14; 95% CI: (1.38, 19.16)]. The results suggested that autistic disorders were associated with perinatal, maternal and antenatal factors such as delivery, pregnancy and maternal characteristics. © 2012 IEEE.},
note = {cited By 0},
keywords = {Antenatal, ASD, Autism, Autistic, Biomedical Engineering, Case-Control Studies, Delivery, Diseases, Hospitals, Logistics, Maternal, Obstetrics, Parents, Perinatal, Pregnancy, Prenatal, Retrospective, Risk Factor},
pubstate = {published},
tppubtype = {conference}
}

Autism disorders are a group of neurodevelopmental disorders which characterized into three main domains which are social interaction impairment, communication delay and repetitive or stereotypic behavior. Many studies had suggested that the risk factors for autism derive from three big factors namely environmental factors, genetic predisposition and vaccine induced. The aim of this study was to investigate the perinatal, maternal and antenatal associated factors on autistic disorder children at Hospital Pulau Pinang and Hospital Bukit Mertajam, Pulau Pinang. A case control study involving 312 cases and control was conducted using data retrieved from hospital records at Pulau Pinang hospital and Bukit Mertajam hospital from 2001 to 2008. The departments involved were Psychiatric, Obstetrics and Gynecology and Record and Management Department. All cases which met the inclusion and exclusion criteria were included in the study. Univariable and multivariable logistic regression were used to explore the perinatal, maternal and antenatal associated factors associated with autistic disorder children. There were seven associated factors contributed most to autistic disorder determination. The factors were maternal age [Adjusted Odds Ratio (OR): 1.41; 95% Confidence Interval (CI): (1.27, 1.57)], maternal smoking reported at first antenatal visit [Adjusted OR: 13.61; 95% CI: (1.87, 99.35)], birth asphyxia [Adjusted OR: 0.35; 95% CI: (0.11, 1.08)], psychiatric history [Adjusted OR: 54.94; 95% CI: (12.07, 250.04)], multiple gestation [Adjusted OR: 4.81; 95% CI: (1.86, 12.45)], parity for more than 4 [Adjusted OR: 0.11; 95% CI: (0.03, 0.47)], parity between 0 and 1 [Adjusted OR: 0.19; 95% CI: (0.07,0.55)], Chinese race compared to the Malay race [Adjusted OR: 10.11; 95% CI: (3.61, 28.30)] and Indian race compared to the Malay race [Adjusted OR: 5.14; 95% CI: (1.38, 19.16)]. The results suggested that autistic disorders were associated with perinatal, maternal and antenatal factors such as delivery, pregnancy and maternal characteristics. © 2012 IEEE.