List of Publications
There are numbers of autism related research can be found in Malaysia that generally focus on the ASD, learning disorder, communication aids, therapy and many more. The list of publications is provided below:
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2020 |
Eow, S Y; Gan, W Y; Lim, P Y; Awang, H; Shariff, Mohd Z Factors associated with autism severity among Malaysian children with Autism Spectrum Disorder Journal Article Research in Developmental Disabilities, 100 , 2020, ISSN: 08914222, (cited By 0). Abstract | Links | BibTeX | Tags: Article, Autism, Body Weight, Children, Cross-Sectional Study, Demography, Disease Association, Disease Severity, Employment, Female, Human, Lifestyle, Major Clinical Study, Malaysia, Malaysian, Male, Parents, Preschool Child, School Child, Social Status @article{Eow2020, title = {Factors associated with autism severity among Malaysian children with Autism Spectrum Disorder}, author = {S Y Eow and W Y Gan and P Y Lim and H Awang and Z Mohd Shariff}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081212440&doi=10.1016%2fj.ridd.2020.103632&partnerID=40&md5=a2814a66b9d649278ea7f764ed7e4125}, doi = {10.1016/j.ridd.2020.103632}, issn = {08914222}, year = {2020}, date = {2020-01-01}, journal = {Research in Developmental Disabilities}, volume = {100}, publisher = {Elsevier Inc.}, abstract = {Background: Children with Autism Spectrum Disorder (ASD) of different levels of symptom severity may exhibit a wide range of behaviours and characteristics. There is a limited nutrition-related study on children with ASD of different severity in Malaysia. Aims: This cross-sectional study aims to determine the association between sociodemographic factors, parental factors, and lifestyle factors with autism severity in children with ASD. Methods and procedures: A total of 224 children with ASD were included in this study. Their mothers completed a self-administered questionnaire on sociodemographic characteristics, autism severity, parenting style, parental feeding practices, parenting stress, child's sleep habits and eating behaviours. Outcomes and results: As high as 78.1 % of the children with ASD demonstrated a high level of autism severity. Multiple linear regression showed that father's employment status (B = 6.970, 95 % CI = 3.172, 10.768, p < 0.001) and perceived child weight (B = 3.338, 95 % CI = 1.350, 5.327}, note = {cited By 0}, keywords = {Article, Autism, Body Weight, Children, Cross-Sectional Study, Demography, Disease Association, Disease Severity, Employment, Female, Human, Lifestyle, Major Clinical Study, Malaysia, Malaysian, Male, Parents, Preschool Child, School Child, Social Status}, pubstate = {published}, tppubtype = {article} } Background: Children with Autism Spectrum Disorder (ASD) of different levels of symptom severity may exhibit a wide range of behaviours and characteristics. There is a limited nutrition-related study on children with ASD of different severity in Malaysia. Aims: This cross-sectional study aims to determine the association between sociodemographic factors, parental factors, and lifestyle factors with autism severity in children with ASD. Methods and procedures: A total of 224 children with ASD were included in this study. Their mothers completed a self-administered questionnaire on sociodemographic characteristics, autism severity, parenting style, parental feeding practices, parenting stress, child's sleep habits and eating behaviours. Outcomes and results: As high as 78.1 % of the children with ASD demonstrated a high level of autism severity. Multiple linear regression showed that father's employment status (B = 6.970, 95 % CI = 3.172, 10.768, p < 0.001) and perceived child weight (B = 3.338, 95 % CI = 1.350, 5.327 |
de Vries, M; Cader, S; Colleer, L; Batteux, E; Yasdiman, M B; Tan, Y J; Sheppard, E University Students’ Notion of Autism Spectrum Conditions: A Cross-Cultural Study Journal Article Journal of Autism and Developmental Disorders, 50 (4), pp. 1281-1294, 2020, ISSN: 01623257, (cited By 0). Abstract | Links | BibTeX | Tags: Adult, Article, Attitude to Health, Autism, Female, Health Belief, Human, Knowledge, Likert Scale, Major Clinical Study, Malaysia, Malaysian, Male, Priority Journal, Social Acceptance, Social Interactions, Sociology, Student Attitude, Students, United Kingdom, University Student, Young Adult @article{deVries20201281, title = {University Students’ Notion of Autism Spectrum Conditions: A Cross-Cultural Study}, author = {M de Vries and S Cader and L Colleer and E Batteux and M B Yasdiman and Y J Tan and E Sheppard}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077543652&doi=10.1007%2fs10803-019-04343-z&partnerID=40&md5=53dc04b76c29629e875adaf44a9831b6}, doi = {10.1007/s10803-019-04343-z}, issn = {01623257}, year = {2020}, date = {2020-01-01}, journal = {Journal of Autism and Developmental Disorders}, volume = {50}, number = {4}, pages = {1281-1294}, publisher = {Springer}, abstract = {Cultural background might influence knowledge and attitudes regarding autism, influencing willingness to interact. We studied whether beliefs, knowledge, contact, and attitude differed between the UK and Malaysia. With mediation analyses, we studied how these factors influenced willingness to interact. Autism was more often linked to food in the UK, and to upbringing in Malaysia. Knowledge, contact, and acceptance were greater in the UK. When excluding psychology students, Malaysian students were less willing to interact with autistic people. Knowledge and contact appeared to improve acceptance, but acceptance did not mediate the relation between country, beliefs, knowledge, and experience; and willingness to interact. Knowledge and contact regarding autism might improve acceptance in different cultures, but how acceptance could improve interaction is unclear. © 2020, The Author(s).}, note = {cited By 0}, keywords = {Adult, Article, Attitude to Health, Autism, Female, Health Belief, Human, Knowledge, Likert Scale, Major Clinical Study, Malaysia, Malaysian, Male, Priority Journal, Social Acceptance, Social Interactions, Sociology, Student Attitude, Students, United Kingdom, University Student, Young Adult}, pubstate = {published}, tppubtype = {article} } Cultural background might influence knowledge and attitudes regarding autism, influencing willingness to interact. We studied whether beliefs, knowledge, contact, and attitude differed between the UK and Malaysia. With mediation analyses, we studied how these factors influenced willingness to interact. Autism was more often linked to food in the UK, and to upbringing in Malaysia. Knowledge, contact, and acceptance were greater in the UK. When excluding psychology students, Malaysian students were less willing to interact with autistic people. Knowledge and contact appeared to improve acceptance, but acceptance did not mediate the relation between country, beliefs, knowledge, and experience; and willingness to interact. Knowledge and contact regarding autism might improve acceptance in different cultures, but how acceptance could improve interaction is unclear. © 2020, The Author(s). |
2019 |
Nor, N K; Ghozali, A H; Ismail, J Prevalence of overweight and obesity among children and adolescents with autism spectrum disorder and associated risk factors Journal Article Frontiers in Pediatrics, 7 (FEB), 2019, ISSN: 22962360, (cited By 5). Abstract | Links | BibTeX | Tags: Adolescent, Adult, Article, Autism, Body Mass, Brief Autism Mealtime Beahavior Questionnaire, Child Development, Childhood Obesity, Children, Children Sleep Habits Questionnaire, Controlled Study, Cross-Sectional Study, Feeding Difficulty, Female, Food Refusal, Human, Major Clinical Study, Malaysian, Male, Mother, Paternal Age, Physical Activity, Physical Activity for Older Children Questionnaire, Prevalence, Questionnaires, Risk Factor, Sleep Disorder, Underweight @article{Nor2019, title = {Prevalence of overweight and obesity among children and adolescents with autism spectrum disorder and associated risk factors}, author = {N K Nor and A H Ghozali and J Ismail}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064414280&doi=10.3389%2ffped.2019.00038&partnerID=40&md5=4bb61b1df043a4adf79618e223d77f26}, doi = {10.3389/fped.2019.00038}, issn = {22962360}, year = {2019}, date = {2019-01-01}, journal = {Frontiers in Pediatrics}, volume = {7}, number = {FEB}, publisher = {Frontiers Media S.A.}, abstract = {Introduction: Prevalence of obesity in Autism Spectrum Disorder (ASD) has been reported to be higher than in the general population. Determining prevalence may help increase awareness of obesity in ASD and potentially lead to initiatives to reduce obesity. In order to understand obesity in ASD children, common risk factors were assessed including physical activity, feeding problems and sleep disturbances. Methods: This is a cross-sectional study performed at the Child Development Center at Universiti Kebangsaan Malaysia Medical Center on 151 ASD children aged 2-18 years. Anthropometric and demographic information were obtained and parents completed three questionnaires; Children Sleep Habits Questionnaire (CSHQ), Physical Activity for Older Children Questionnaire (PAQ-C) and Brief Autism Mealtime Behavior Questionnaire (BAMBI). Results: For ASD children in our sample, the prevalence of overweight (BMI ≥85th to < 95th percentiles) was 11.3% and the prevalence of obesity (BMI ≥95th percentile) was 21.9%. The overweight/obese ASD children's median age was higher at 8.5 years (IQR 5.81-10.13) compared to the normal/underweight group of 6.33 years (IQR 4.75-7.7) with a p-value of 0.001. The two groups also differed significantly for maternal BMI and paternal age. The median maternal BMI in the overweight/obese group was 26.05 (IQR 23.35-32.25), statistically significantly higher (p = 0.003) than in the non-overweight/obese group, 24.7 (IQR 21-27.9). The median paternal age of 40 years (IQR 37-44) was statistically significantly higher (p = 0.039) in the overweight/obese group, compared to the median paternal age in the non-overweight/obese group of 38 (IQR 35-42). The male overweight/obese children had median PAQ-C score of 2.44 (IQR 2.00-3.00) vs. 2.89 (IQR 2.35-3.53) in the counterpart group with a p-value of 0.01. Using the multiple linear regression stepwise method, three predictors associated with BMI percentiles reached a statistical level of significance; PAQ-C score in males (p < 0.001), the BAMBI domains of Food Refusal (p = 0.001) and Limited Variety of Food (p = 0.001). Conclusions: The prevalence of obesity and overweight is high among Malaysian ASD children and adolescents. Older child age, high maternal BMI, older paternal age, low physical activity, low likelihood of food refusal and high likelihood of food selectivity were found to be risk factors for high BMI in these children. © 2019 Kamal Nor, Ghozali and Ismail.}, note = {cited By 5}, keywords = {Adolescent, Adult, Article, Autism, Body Mass, Brief Autism Mealtime Beahavior Questionnaire, Child Development, Childhood Obesity, Children, Children Sleep Habits Questionnaire, Controlled Study, Cross-Sectional Study, Feeding Difficulty, Female, Food Refusal, Human, Major Clinical Study, Malaysian, Male, Mother, Paternal Age, Physical Activity, Physical Activity for Older Children Questionnaire, Prevalence, Questionnaires, Risk Factor, Sleep Disorder, Underweight}, pubstate = {published}, tppubtype = {article} } Introduction: Prevalence of obesity in Autism Spectrum Disorder (ASD) has been reported to be higher than in the general population. Determining prevalence may help increase awareness of obesity in ASD and potentially lead to initiatives to reduce obesity. In order to understand obesity in ASD children, common risk factors were assessed including physical activity, feeding problems and sleep disturbances. Methods: This is a cross-sectional study performed at the Child Development Center at Universiti Kebangsaan Malaysia Medical Center on 151 ASD children aged 2-18 years. Anthropometric and demographic information were obtained and parents completed three questionnaires; Children Sleep Habits Questionnaire (CSHQ), Physical Activity for Older Children Questionnaire (PAQ-C) and Brief Autism Mealtime Behavior Questionnaire (BAMBI). Results: For ASD children in our sample, the prevalence of overweight (BMI ≥85th to < 95th percentiles) was 11.3% and the prevalence of obesity (BMI ≥95th percentile) was 21.9%. The overweight/obese ASD children's median age was higher at 8.5 years (IQR 5.81-10.13) compared to the normal/underweight group of 6.33 years (IQR 4.75-7.7) with a p-value of 0.001. The two groups also differed significantly for maternal BMI and paternal age. The median maternal BMI in the overweight/obese group was 26.05 (IQR 23.35-32.25), statistically significantly higher (p = 0.003) than in the non-overweight/obese group, 24.7 (IQR 21-27.9). The median paternal age of 40 years (IQR 37-44) was statistically significantly higher (p = 0.039) in the overweight/obese group, compared to the median paternal age in the non-overweight/obese group of 38 (IQR 35-42). The male overweight/obese children had median PAQ-C score of 2.44 (IQR 2.00-3.00) vs. 2.89 (IQR 2.35-3.53) in the counterpart group with a p-value of 0.01. Using the multiple linear regression stepwise method, three predictors associated with BMI percentiles reached a statistical level of significance; PAQ-C score in males (p < 0.001), the BAMBI domains of Food Refusal (p = 0.001) and Limited Variety of Food (p = 0.001). Conclusions: The prevalence of obesity and overweight is high among Malaysian ASD children and adolescents. Older child age, high maternal BMI, older paternal age, low physical activity, low likelihood of food refusal and high likelihood of food selectivity were found to be risk factors for high BMI in these children. © 2019 Kamal Nor, Ghozali and Ismail. |
2014 |
Chen, B C; Rawi, Mohd R; Meinsma, R; Meijer, J; Hennekam, R C M; Kuilenburg, Van A B P Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings Journal Article Molecular Syndromology, 5 (6), pp. 299-303, 2014, ISSN: 16618769, (cited By 4). Abstract | Links | BibTeX | Tags: Alanine, Article, Asymptomatic Disease, Autism, Autosomal Recessive Disorder, Case Report, Cerebellum Atrophy, Children, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Disease Severity, DPYD Gene, Eye Malformation, Female, Gene, Gene Mutation, Homozygosity, Human, Intellectual Impairment, Malaysian, Male, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Preschool Child, Pyrimidine, Pyrimidine Metabolism, School Child, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil @article{Chen2014299, title = {Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings}, author = {B C Chen and R Mohd Rawi and R Meinsma and J Meijer and R C M Hennekam and A B P Van Kuilenburg}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919783242&doi=10.1159%2f000366074&partnerID=40&md5=1ebfb9aedb7cb64e3423811b41b6aa7c}, doi = {10.1159/000366074}, issn = {16618769}, year = {2014}, date = {2014-01-01}, journal = {Molecular Syndromology}, volume = {5}, number = {6}, pages = {299-303}, publisher = {S. Karger AG}, abstract = {Dihydropyrimidine dehydrogenase (DPD) deficiency is an autosomal recessive disorder of the pyrimidine metabolism. Deficiency of this enzyme leads to an accumulation of thymine and uracil and a deficiency of metabolites distal to the catabolic enzyme. The disorder presents with a wide clinical spectrum, ranging from asymptomatic to severe neurological manifestations, including intellectual disability, seizures, microcephaly, autistic behavior, and eye abnormalities. Here, we report on an 11-year-old Malaysian girl and her 6-year-old brother with DPD deficiency who presented with intellectual disability, microcephaly, and hypotonia. Brain MRI scans showed generalized cerebral and cerebellar atrophy and callosal body dysgenesis in the boy. Urine analysis showed strongly elevated levels of uracil in the girl and boy (571 and 578 mmol/mol creatinine, respectively) and thymine (425 and 427 mmol/mol creatinine, respectively). Sequence analysis of the DPYD gene showed that both siblings were homozygous for the mutation c.1651G>A (pAla551Thr). © 2014 S. Karger AG, Basel.}, note = {cited By 4}, keywords = {Alanine, Article, Asymptomatic Disease, Autism, Autosomal Recessive Disorder, Case Report, Cerebellum Atrophy, Children, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Disease Severity, DPYD Gene, Eye Malformation, Female, Gene, Gene Mutation, Homozygosity, Human, Intellectual Impairment, Malaysian, Male, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Preschool Child, Pyrimidine, Pyrimidine Metabolism, School Child, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil}, pubstate = {published}, tppubtype = {article} } Dihydropyrimidine dehydrogenase (DPD) deficiency is an autosomal recessive disorder of the pyrimidine metabolism. Deficiency of this enzyme leads to an accumulation of thymine and uracil and a deficiency of metabolites distal to the catabolic enzyme. The disorder presents with a wide clinical spectrum, ranging from asymptomatic to severe neurological manifestations, including intellectual disability, seizures, microcephaly, autistic behavior, and eye abnormalities. Here, we report on an 11-year-old Malaysian girl and her 6-year-old brother with DPD deficiency who presented with intellectual disability, microcephaly, and hypotonia. Brain MRI scans showed generalized cerebral and cerebellar atrophy and callosal body dysgenesis in the boy. Urine analysis showed strongly elevated levels of uracil in the girl and boy (571 and 578 mmol/mol creatinine, respectively) and thymine (425 and 427 mmol/mol creatinine, respectively). Sequence analysis of the DPYD gene showed that both siblings were homozygous for the mutation c.1651G>A (pAla551Thr). © 2014 S. Karger AG, Basel. |
2013 |
Mustafa, M; Arshad, H; Zaman, H B Framework methodology of the Autism children - Vibratory haptic interface (AC-VHI) Conference IEEE Computer Society, 2013, ISBN: 9781479927586, (cited By 1). Abstract | Links | BibTeX | Tags: Autistic Children, Children with Autism, Diseases, Haptic Interfaces, Malaysia, Malaysian, Mice, Mild Autism, Probability Sampling, Sample Collection, Social Interactions, Structured Observation @conference{Mustafa2013201, title = {Framework methodology of the Autism children - Vibratory haptic interface (AC-VHI)}, author = {M Mustafa and H Arshad and H B Zaman}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904211710&doi=10.1109%2fACSAT.2013.47&partnerID=40&md5=12c910cd01ef0874e09e8e51e2c00b3c}, doi = {10.1109/ACSAT.2013.47}, isbn = {9781479927586}, year = {2013}, date = {2013-01-01}, journal = {Proceedings - 2013 International Conference on Advanced Computer Science Applications and Technologies, ACSAT 2013}, pages = {201-206}, publisher = {IEEE Computer Society}, abstract = {This paper provides the Framework Methodology of the Autism Children -Vibratory Haptic Interface (AC-VHI) conducted on the mild autism children who have impairment in social interaction. This paper has exclusively explored problems faced by Malaysian autistic children in a National Autism Society at Kuala Lumpur, Malaysia. It also has been conducted at two locations: the classroom and the court of the National Autism Society in Malaysia (NASOM), Kuala Lumpur, Malaysia. The paper has sampled 20 children with mild autism, who have impairment in social interaction, based on the records of the National Autism Society of Malaysia. The sample collection method followed the purposive sampling approach, which is a form of non-probability sampling that allowed us to choose a case, because it illustrates some features or processes, in which we are interested. The framework included three main three process which are Process one, process Two and Process Three. This's three processes of the framework was suitable with the area of research and could to accomplish objectives of this research in helping the autism children to interact and communicate effectively with their families, friends and the broad community. The framework included three main three process which are Process one, process Two and Process Three. This's three processes of the framework was suitable with the area of research and could to accomplish objectives of this research in helping the autism children to interact and communicate effectively with their families, friends and the broad community. © 2013 IEEE.}, note = {cited By 1}, keywords = {Autistic Children, Children with Autism, Diseases, Haptic Interfaces, Malaysia, Malaysian, Mice, Mild Autism, Probability Sampling, Sample Collection, Social Interactions, Structured Observation}, pubstate = {published}, tppubtype = {conference} } This paper provides the Framework Methodology of the Autism Children -Vibratory Haptic Interface (AC-VHI) conducted on the mild autism children who have impairment in social interaction. This paper has exclusively explored problems faced by Malaysian autistic children in a National Autism Society at Kuala Lumpur, Malaysia. It also has been conducted at two locations: the classroom and the court of the National Autism Society in Malaysia (NASOM), Kuala Lumpur, Malaysia. The paper has sampled 20 children with mild autism, who have impairment in social interaction, based on the records of the National Autism Society of Malaysia. The sample collection method followed the purposive sampling approach, which is a form of non-probability sampling that allowed us to choose a case, because it illustrates some features or processes, in which we are interested. The framework included three main three process which are Process one, process Two and Process Three. This's three processes of the framework was suitable with the area of research and could to accomplish objectives of this research in helping the autism children to interact and communicate effectively with their families, friends and the broad community. The framework included three main three process which are Process one, process Two and Process Three. This's three processes of the framework was suitable with the area of research and could to accomplish objectives of this research in helping the autism children to interact and communicate effectively with their families, friends and the broad community. © 2013 IEEE. |