Ujian - National Autism Resource Centre (NARC)

Eow, S Y; Gan, W Y; Lim, P Y; Awang, H; Shariff, Mohd Z

Faktor-faktor yang berkaitan dengan keparahan autisme di kalangan kanak-kanak Malaysia dengan Autism Spectrum Disorder Artikel Jurnal

Penyelidikan Ketidakupayaan Pembangunan, 100 , 2020, ISSN: 08914222, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Berat badan, Anak-anak, Kajian Lintas Bahagian, Demografi, Persatuan Penyakit, Keterukan Penyakit, Pekerjaan, Perempuan, Manusia, Gaya hidup, Kajian Klinikal Utama, Malaysia, Orang Malaysia, Lelaki, Ibu bapa, Kanak-kanak Prasekolah, Budak sekolah, Status sosial

Djatmika, ; Wibowo, A H; Sugini, ; Halim, H; Mohamad, B

Strategi multimodal dalam mengajar kanak-kanak dengan autisme: Analisis wacana Artikel Jurnal

Ulasan Sistematik di Farmasi, 11 (2), hlm. 219-229, 2020, ISSN: 09758453, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Pergerakan Badan, Anak-anak, Analisis Wacana, Gerak isyarat, Manusia, Bahasa, Kesunyian, Perhubungan tanpa percakapan, Paralanguage, Jurnal Keutamaan, Berdiri, Perancangan strategik, Pelajar, Cikgu, Mengajar, Tingkah laku Lisan, Komunikasi Lisan

Singh, Balbir H K; Badgujar, V B; Yahaya, R S; Rahman, Abd S; Bersendirian, F M; Badgujar, S; Govindan, S N; Ansari, M T

Assessment of knowledge and attitude among postnatal mothers towards childhood vaccination in Malaysia Artikel Jurnal

Human Vaccines and Immunotherapeutics, 15 (11), hlm. 2544-2551, 2019, ISSN: 21645515, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Attitude, Sikap Terhadap Kesihatan, Autisme, Child Health, Childhood Vaccination, Anak-anak, Kajian Lintas Bahagian, Diphtheria Pertussis Poliomyelitis Tetanus Haemophilus Influenzae Type B Hepatitis B Vaccine, Pendidikan, Pekerjaan, Etnik, Perempuan, Health Knowledge, Manusia, Immunization Programs, Pengetahuan, Skala Likert, Kajian Klinikal Utama, Malaysia, Ibu, Mothers, Needs Assessment, Occupation, Postnatal Care, Practice, Kanak-kanak Prasekolah, Preventive Health Service, Psikologi, Soal selidik, Seasonal Influenza, Tinjauan, Vaccination, Dewasa Muda

Ramachandram, S

Clinical characteristics and demographic profile of children with autism spectrum disorder (Asd) at child development clinic (cdc), penang hospital, malaysia Artikel Jurnal

Medical Journal of Malaysia, 74 (5), hlm. 372-376, 2019, ISSN: 03005283, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Remaja, Artikel, Asthma, Autisme, Birth Weight, Pembangunan kanak-kanak, Anak-anak, Chinese, Conception, Demografi, Diet Restriction, DSM-5, Eczema, Pendidikan, Educational Status, Epilepsi, Perempuan, Genetic Disorder, Heart Atrium Septum Defect, Heart Ventricle Septum Defect, Manusia, Orang India, Kajian Klinikal Utama, Malay, Lelaki, Medical Record Review, Pulau Pinang, Prematurity, Gangguan Pertuturan, Upper Respiratory Tract Congestion, Wakefulness

Khan, N A; Soopramanien, M; Siddiqui, R

Buaya dan buaya: Jawapan doktor untuk barah? Artikel Jurnal

Onkologi Semasa, 26 (3), hlm. 186, 2019, ISSN: 11980052, (dipetik oleh 1).

Pautan | BibTeX | Tag: Penyakit Alergi, Buaya dan Buaya, Produk Haiwan, Haiwan, Aktiviti Antineoplastik, Ejen Antineoplastik, Artikel, Dermatitis Atopik, Autisme, Pertumbuhan Barah, Terapi Barah, Karsinogen, Organisma yang tercemar, Buaya, Kepupusan Massa Cretaceous Akhir, Faktor Persekitaran, Tekanan Alam Sekitar, Mikrobioma gastrousus, Tingkah laku Kesihatan, Logam berat, Manusia, Sistem Imun, Penyakit Usus Keradangan, Flora usus, Panjang umur, Gangguan Metabolik, Mikrobiologi, Neoplasma, Neoplasma, Pembezaan Sel Saraf, Pakar Perubatan, Skizofrenia, Analisis Survival, Penyakit Terminal

Liu, Y-W; Liong, M T; Am, Y -C E; Huang, H -Y; Peng, W -S; Cheng, Y -F; Lin, Y -S; Wu, Y-Y; Tsai, Y -C

Kesan lactobacillus plantarum PS128 pada kanak-kanak dengan gangguan spektrum autisme di Taiwan: A rawak, buta dua, percubaan terkawal plasebo Artikel Jurnal

Nutrien, 11 (4), 2019, ISSN: 20726643, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Senarai Semak Tingkah Laku Aberrant versi Taiwan, Remaja, umur, Faktor Umur, Keagresifan, Keresahan, Artikel, Gangguan Defisit Perhatian, Autisme, Senarai Semak Tingkah Laku Autisme, Temuduga Diagnostik Autisme Disemak, Gangguan Spektrum Autisme, Tingkah Laku Kanak-kanak, Senarai Semak Tingkah Laku Kanak-kanak, Anak-anak, Skala Teraan Global Klinikal, Gangguan Komunikasi, Kajian Terkawal, Prosedur Double Blind, Kaedah Double-Blind, Perempuan, Gangguan Kebimbangan Umum, Manusia, Impulsif, Lactobacillus delbrueckii, Lelaki, Fisiologi, Placebo, Placebo, Gangguan Tekanan Selepas Traumatik, Agen Probiotik, Probiotik, Psikologi, Soal selidik, Percubaan Terkawal Rawak, Skala penilaian, Budak sekolah, Sistem Pemarkahan, Kelakuan Sosial, Interaksi Sosial, Masalah Sosial, Skala Responsif Sosial, Tinjauan, Penilaian Swanson Nolan dan Pelham IV, Protein Berkaitan Sinaptosomal 23, Taiwan

Jaafar, N H; Othman, A; Majid, N A; Harith, S; Zabidi-Hussin, DENGAN

Parent-report instruments for assessing feeding difficulties in children with neurological impairments: a systematic review Artikel Jurnal

Developmental Medicine and Child Neurology, 61 (2), hlm. 135-144, 2019, ISSN: 00121622, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: Assessment of Humans, Autisme, Behavioural Paediatric Feeding Assessment Scale, Caloric Intake, Tingkah Laku Kanak-kanak, Hubungan Ibu Bapa Anak, Childhood Disease, Anak-anak, Children's Eating Behaviour Inventory, Komplikasi, Construct Validity, Content Validity, Criterion Related Validity, Cystic Fibrosis, Gangguan Makan, Enalapril Maleate, Eosinophilic Gastrointestinal Disorder, Esophagus Atresia, Feeding, Feeding and Eating Disorders, Tingkah Laku Makan, Kesukaran Memberi Makan, Pengambilan makanan, Manusia, Nervous System Diseases, Neurologic Disease, Penilaian Pemakanan, Ibu bapa, Pediatric Assessment Scale for Severe Feeding Problem, Pediatric Eating Assessment Tool, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Psikometrik, Psikometri, Kualiti hidup, Receiver Operating Characteristic, Kaji semula, Sistem Pemarkahan, Self Disclosure, Kepekaan dan Kekhususan, Syndrome CHARGE, Kajian Sistematik, Test Retest Reliability

Al-Hiyali, M Saya; Ishak, A J; Harun, H; Ahmad, S A; Sulaiman, Wan W A

Tinjauan dalam mengubah suai tingkah laku pengambilan makanan oleh rangsangan otak: Kes berat badan berlebihan Artikel Jurnal

Kuantologi Neuro, 16 (12), hlm. 86-97, 2018, ISSN: 13035150, (dipetik oleh 2).

Abstrak | Pautan | BibTeX | Tag: Amygdala, Anoksia, Artikel, Autisme, Gangguan pesta minum-minum makan, Berat badan, Berat badan, Rangsangan Kedalaman Otak, Depolarisasi, Pengambilan diet, Keinginan Dadah, Gangguan Makan, Arus elektrik, Elektroencephalogram, Elektroensefalografi, Penggunaan tenaga, Penggunaan tenaga, Tingkah Laku Makan, Pengambilan makanan, Pengimejan Resonans Magnetik Berfungsi, Jantina, Status kesihatan, Homeostasis, Manusia, Kelaparan, Gaya hidup, Potensi Mantap Membran Sel Saraf, Keseronokan Saraf, Neurofeedback, Neuromodulasi, Penilaian Pemakanan, Penilaian Hasil, Soal selidik, Rangsangan Magnetik Transkranial Berulang, Pemprosesan isyarat, Latihan, Rangsangan Arus Langsung Transkranial, Rangsangan Magnetik Transkranial, Berat badan kurang

Toh, T -H; Tan, V W -Y; Lau, PST; Kiyu, A

Ketepatan Senarai Semak Perubahan untuk Autisme pada Kanak-kanak (M-CHAT) dalam Mengesan Autisme dan Gangguan Perkembangan Lain di Klinik Komuniti Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 48 (1), hlm. 28-35, 2018, ISSN: 01623257, (dipetik oleh 9).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Penilaian Autisme, Gangguan Spektrum Autisme, Senarai semak, Anak-anak, Analisis Kohort, Kajian Kohort, Pusat Kesihatan Komuniti, Gangguan Perkembangan, Ketepatan Diagnostik, Perempuan, Pusat kesihatan, Manusia, Bayi, Kajian Klinikal Utama, Malaysia, Lelaki, Pemeriksaan Massa, Senarai Semak yang Diubahsuai untuk Autisme pada Kanak-kanak, Hospital Pediatrik, Nilai Ramalan, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Prosedur, Psikologi, Kajian Retrospektif, Kajian Retrospektif, Kepekaan dan Kekhususan, Piawaian, Kanak-kanak kecil

Diurut, R

Autisme dan trikotilomania dalam remaja lelaki Artikel Jurnal

Laporan Kes BMJ, 2018 , 2018, ISSN: 1757790X, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Remaja, Alopecia, Keresahan, Artikel, Gangguan Defisit Perhatian, Gangguan Hiperaktifan Kekurangan Perhatian, Autisme, Gangguan Spektrum Autisme, Gangguan Tingkah Laku, Berat badan, Laporan kes, Perangsang Sistem Saraf Pusat, Senarai Semak Tingkah Laku Kanak-kanak, Artikel Klinikal, komorbiditi, Komplikasi, Diagnosis, Berbeza, Diagnosis pembezaan, Pentitratan Dos Ubat, Toleransi Dadah, DSM-5, Echolalia, Fluvoxamine, Susulan, Manusia, Hiperaktif, Kemerosotan Intelektual, Lelaki, Metilfenidat, Obesiti, Terapi pekerjaan, Indeks Penaakulan Persepsi, Jurnal Keutamaan, Indeks Kelajuan Pemprosesan, Skala Penarafan Status Psikiatri, Skala Penarafan Psikologi, Skala penilaian, Kegelisahan, Ganjaran, Perencat Serapan Serotonin, Perencat Serapan Serotonin, Pendidikan Khas, Kelewatan Pertuturan, Gangguan Pertuturan, Terapi ucapan, Trikotilomania, Indeks Kefahaman Lisan, Skala Kepintaran Wechsler, Indeks Memori Bekerja

Tsuchida, N; Hamada, K; Shiina, M; Kato, M; Kobayashi, Y; Tohyama, J; Kimura, K; Hoshino, K; Ganesan, V; Teik, K W; Nakashima, M; Mitsuhashi, S; Mizuguchi, T; Takata, A; Miyake, N; Saitsu, H; Ogata, K; Miyatake, S; Matsumoto, N

GRIN2D variants in three cases of developmental and epileptic encephalopathy Artikel Jurnal

Clinical Genetics, 94 (6), hlm. 538-547, 2018, ISSN: 00099163, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing

@artikel{Tsuchida2018538,
tajuk = {GRIN2D variants in three cases of developmental and epileptic encephalopathy},
pengarang = {N Tsuchida and K Hamada and M Shiina and M Kato and Y Kobayashi and J Tohyama and K Kimura and K Hoshino and V Ganesan and K W Teik and M Nakashima and S Mitsuhashi and T Mizuguchi and A Takata and N Miyake and H Saitsu and K Ogata and S Miyatake and N Matsumoto},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056487337&doi=10.1111%2fcge.13454&rakan kongsi = 40&md5=f0d32670db57261820bc244943cffd62},
doi = {10.1111/cge.13454},
terbitan = {00099163},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {Clinical Genetics},
isi padu = {94},
nombor = {6},
halaman = {538-547},
penerbit = {Blackwell Publishing Ltd},
abstrak = {N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Baru-baru ini, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. Dalam kajian ini, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd},
nota = {dipetik oleh 4},
kata kunci = {Remaja, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Artikel, Atonic Seizure, Gangguan Defisit Perhatian, Autisme, Binding Affinity, Otak, Brain Atrophy, Carbamazepine, Laporan kes, Channel Gating, Kimia, Anak-anak, Artikel Klinikal, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Kelewatan Perkembangan, Gangguan Perkembangan, Elektroencephalogram, Elektroensefalografi, Epilepsi, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Perempuan, Frontal Lobe Epilepsy, Gen, Gene Frequency, Genetic Variation, Genetik, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Manusia, Sel Manusia, Hydrogen Bond, Kemerosotan Intelektual, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Lelaki, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Prasekolah, Kanak-kanak Prasekolah, Jurnal Keutamaan, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, Budak sekolah, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Hariharan, M; Sindhu, R; Vijean, V; Yazid, H; Nadarajaw, T; Yaacob, S; Polat, K

Improved binary dragonfly optimization algorithm and wavelet packet based non-linear features for infant cry classification Artikel Jurnal

Computer Methods and Programs in Biomedicine, 155 , hlm. 39-51, 2018, ISSN: 01692607, (dipetik oleh 21).

Abstrak | Pautan | BibTeX | Tag: Accidents, Algoritma, Artikel, Artificial Neural Network, Asphyxia, Binary Dragonfly Optimization Aalgorithm, Pengelasan (maklumat), Classification Algorithm, Pengelas, Coding, Computer-Assisted, Constants and Coefficients, Crying, Database Systems, Databases, Deafness, Diagnosis, Energy, Entropy, Pengekstrakan, Extreme Learning Machine, Factual, Factual Database, Pengekstrakan Ciri, Kaedah Pemilihan Ciri, Fuzzy System, Hearing Impairment, Manusia, Kelaparan, Bayi, Infant Cry, Infant Cry Classifications, Jaundice, Kernel Method, Belajar, Linear Predictive Coding, Pembelajaran Mesin, Mathematical Transformations, Mel Frequency Cepstral Coefficient, Pekali Cepstral Frekuensi Mel, Multi-Class Classification, Rangkaian Neural, Nonlinear Dynamics, Nonlinear System, Optimization, Pain, Patofisiologi, Prematurity, Kebolehulangan, Kebolehulangan Keputusan, Pemprosesan isyarat, Pengenalan suara, Wavelet Analysis, Wavelet Packet, Paket Wavelet Berubah

@artikel{Hariharan201839,
tajuk = {Improved binary dragonfly optimization algorithm and wavelet packet based non-linear features for infant cry classification},
pengarang = {M Hariharan and R Sindhu and V Vijean and H Yazid and T Nadarajaw and S Yaacob and K Polat},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85036611215&doi=10.1016%2fj.cmpb.2017.11.021&rakan kongsi = 40&md5=1f3b17817b00f07cadad6eb61c0f4bf9},
doi = {10.1016/j.cmpb.2017.11.021},
terbitan = {01692607},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {Computer Methods and Programs in Biomedicine},
isi padu = {155},
halaman = {39-51},
penerbit = {Elsevier Ireland Ltd},
abstrak = {Background and objective Infant cry signal carries several levels of information about the reason for crying (hunger, pain, sleepiness and discomfort) or the pathological status (asphyxia, deaf, jaundice, premature condition and autism, etc.) of an infant and therefore suited for early diagnosis. Dalam kerja ini, combination of wavelet packet based features and Improved Binary Dragonfly Optimization based feature selection method was proposed to classify the different types of infant cry signals. Methods Cry signals from 2 different databases were utilized. First database contains 507 cry samples of normal (N), 340 cry samples of asphyxia (A), 879 cry samples of deaf (D), 350 cry samples of hungry (H) dan 192 cry samples of pain (P). Second database contains 513 cry samples of jaundice (J), 531 samples of premature (Prem) dan 45 samples of normal (N). Wavelet packet transform based energy and non-linear entropies (496 ciri-ciri), Linear Predictive Coding (LPC) based cepstral features (56 ciri-ciri), Mel-frequency Cepstral Coefficients (MFCCs) were extracted (16 ciri-ciri). The combined feature set consists of 568 ciri-ciri. To overcome the curse of dimensionality issue, improved binary dragonfly optimization algorithm (IBDFO) was proposed to select the most salient attributes or features. Akhirnya, Extreme Learning Machine (ELM) kernel classifier was used to classify the different types of infant cry signals using all the features and highly informative features as well. Results Several experiments of two-class and multi-class classification of cry signals were conducted. In binary or two-class experiments, maximum accuracy of 90.18% for H Vs P, 100% for A Vs N, 100% for D Vs N and 97.61% J Vs Prem was achieved using the features selected (only 204 features out of 568) by IBDFO. For the classification of multiple cry signals (multi-class problem), the selected features could differentiate between three classes (N, A & D) with the accuracy of 100% and seven classes with the accuracy of 97.62%. Conclusion The experimental results indicated that the proposed combination of feature extraction and selection method offers suitable classification accuracy and may be employed to detect the subtle changes in the cry signals. © 2017 Elsevier B.V.},
nota = {dipetik oleh 21},
kata kunci = {Accidents, Algoritma, Artikel, Artificial Neural Network, Asphyxia, Binary Dragonfly Optimization Aalgorithm, Pengelasan (maklumat), Classification Algorithm, Pengelas, Coding, Computer-Assisted, Constants and Coefficients, Crying, Database Systems, Databases, Deafness, Diagnosis, Energy, Entropy, Pengekstrakan, Extreme Learning Machine, Factual, Factual Database, Pengekstrakan Ciri, Kaedah Pemilihan Ciri, Fuzzy System, Hearing Impairment, Manusia, Kelaparan, Bayi, Infant Cry, Infant Cry Classifications, Jaundice, Kernel Method, Belajar, Linear Predictive Coding, Pembelajaran Mesin, Mathematical Transformations, Mel Frequency Cepstral Coefficient, Pekali Cepstral Frekuensi Mel, Multi-Class Classification, Rangkaian Neural, Nonlinear Dynamics, Nonlinear System, Optimization, Pain, Patofisiologi, Prematurity, Kebolehulangan, Kebolehulangan Keputusan, Pemprosesan isyarat, Pengenalan suara, Wavelet Analysis, Wavelet Packet, Paket Wavelet Berubah},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Background and objective Infant cry signal carries several levels of information about the reason for crying (hunger, pain, sleepiness and discomfort) or the pathological status (asphyxia, deaf, jaundice, premature condition and autism, etc.) of an infant and therefore suited for early diagnosis. Dalam kerja ini, combination of wavelet packet based features and Improved Binary Dragonfly Optimization based feature selection method was proposed to classify the different types of infant cry signals. Methods Cry signals from 2 different databases were utilized. First database contains 507 cry samples of normal (N), 340 cry samples of asphyxia (A), 879 cry samples of deaf (D), 350 cry samples of hungry (H) dan 192 cry samples of pain (P). Second database contains 513 cry samples of jaundice (J), 531 samples of premature (Prem) dan 45 samples of normal (N). Wavelet packet transform based energy and non-linear entropies (496 ciri-ciri), Linear Predictive Coding (LPC) based cepstral features (56 ciri-ciri), Mel-frequency Cepstral Coefficients (MFCCs) were extracted (16 ciri-ciri). The combined feature set consists of 568 ciri-ciri. To overcome the curse of dimensionality issue, improved binary dragonfly optimization algorithm (IBDFO) was proposed to select the most salient attributes or features. Akhirnya, Extreme Learning Machine (ELM) kernel classifier was used to classify the different types of infant cry signals using all the features and highly informative features as well. Results Several experiments of two-class and multi-class classification of cry signals were conducted. In binary or two-class experiments, maximum accuracy of 90.18% for H Vs P, 100% for A Vs N, 100% for D Vs N and 97.61% J Vs Prem was achieved using the features selected (only 204 features out of 568) by IBDFO. For the classification of multiple cry signals (multi-class problem), the selected features could differentiate between three classes (N, A & D) with the accuracy of 100% and seven classes with the accuracy of 97.62%. Conclusion The experimental results indicated that the proposed combination of feature extraction and selection method offers suitable classification accuracy and may be employed to detect the subtle changes in the cry signals. © 2017 Elsevier B.V.

Tutup

Rendah, H M; Zailan, F

Medical students’ perceptions, kesedaran, societal attitudes and knowledge of autism spectrum disorder: an exploratory study in Malaysia Artikel Jurnal

International Journal of Developmental Disabilities, 64 (2), hlm. 86-95, 2018, ISSN: 20473869, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: Dewasa, Artikel, Autisme, Awareness, Kelakuan, Exploratory Research, Perempuan, Manusia, Pengetahuan, Malaysia, Lelaki, Medical Student, Sikap Pelajar, Pelajar, Symptom

@artikel{Low201886,
tajuk = {Medical students’ perceptions, kesedaran, societal attitudes and knowledge of autism spectrum disorder: an exploratory study in Malaysia},
pengarang = {H M Low and F Zailan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85002273499&doi=10.1080%2f20473869.2016.1264663&rakan kongsi = 40&md5=4b1b16448e16172b2dce10eacf1c3f3d},
doi = {10.1080/20473869.2016.1264663},
terbitan = {20473869},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {International Journal of Developmental Disabilities},
isi padu = {64},
nombor = {2},
halaman = {86-95},
penerbit = {Taylor and Francis Ltd.},
abstrak = {Objektif: This study aimed to investigate the perception, kesedaran, societal attitude, and knowledge about Autism Spectrum Disorder (ASD) in Malaysian medical students. Kaedah: An exploratory survey was conducted with 83 medical students in Malaysia. In the survey, the medical students were required to rate their perception, kesedaran, societal attitude, and their recognition of ASD symptoms. Keputusan: The results showed the senior medical students had increased knowledge about ASD symptoms compared to the juniors, but there was no clear indicator that they had obtained the knowledge through formal training. Secara khusus, the medical students could better identify symptoms related to restrictive and fixation behavioral patterns than social communicative deficits. While considering the effects of societal attitude, year of study, perception about ASD course and other demographic variables, the year of study emerged as the sole predictor of the medical students’ knowledge about ASD. Kesimpulannya: The findings from this study provided evidence for the need of compulsory training on ASD in medical schools in improve the knowledge and skills of prospective medical practitioners to identify individuals with ASD. Such effort is fundamental for the early identification and intervention of ASD in developing countries such as Malaysia. © 2016, © The British Society of Developmental Disabilities 2016.},
nota = {dipetik oleh 1},
kata kunci = {Dewasa, Artikel, Autisme, Awareness, Kelakuan, Exploratory Research, Perempuan, Manusia, Pengetahuan, Malaysia, Lelaki, Medical Student, Sikap Pelajar, Pelajar, Symptom},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Thu, Tidak H; Hussain, DENGAN; Shuid, A N

New insight in improving therapeutic efficacy of antipsychotic agents: An overview of improved in vitro and in vivo performance, efficacy upgradation and future prospects Artikel Jurnal

Current Drug Targets, 19 (8), hlm. 865-876, 2018, ISSN: 13894501, (dipetik oleh 2).

Abstrak | Pautan | BibTeX | Tag: Amisulpride, Amitriptyline, Haiwan, Antipsychotic Agents, Keresahan, Aripiprazole, Autisme, Bioavailability, Biological Availability, Bipolar Disorder, Buspirone, Kimia, Clonazepam, Clozapine, Kemurungan, Diazepam, Drug Delivery System, Drug Delivery Systems, Duloxetine, Half Life Time, Half-Life, Penjagaan Kesihatan, Manusia, Iloperidone, In Vitro Study, In Vivo Study, Mental Disease, Gangguan Mental, Midazolam, Nanotechnology, Neuroleptic Agent, Olanzapine, Patofisiologi, Kebolehtelapan, Physical Chemistry, Psychosis, Kaji semula, Risperidone, Skizofrenia, Solubility, Sulpiride, Hasil Rawatan, Venlafaxine, Ziprasidone

@artikel{EiThu2018865,
tajuk = {New insight in improving therapeutic efficacy of antipsychotic agents: An overview of improved in vitro and in vivo performance, efficacy upgradation and future prospects},
pengarang = {H Ei Thu and Z Hussain and A N Shuid},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048981535&doi=10.2174%2f1389450117666161125174625&rakan kongsi = 40&md5=d32e5bc9766ff9d68dd79f082b9ca4bc},
doi = {10.2174/1389450117666161125174625},
terbitan = {13894501},
tahun = {2018},
tarikh = {2018-01-01},
jurnal = {Current Drug Targets},
isi padu = {19},
nombor = {8},
halaman = {865-876},
penerbit = {Bentham Science Publishers B.V.},
abstrak = {Psychotic disorders are recognized as severe mental disorders that rigorously affect pa-tient’s personality, critical thinking, and perceptional ability. High prevalence, global dissemination and limitations of conventional pharmacological approaches compel a significant burden to the patient, medical professionals and the healthcare system. Sehingga kini, numerous orally administered therapies are available for the management of depressive disorders, schizophrenia, kegelisahan, bipolar disorders and autism spectrum problems. Walau bagaimanapun, poor water solubility, erratic oral absorption, extensive first-pass metabolism, low oral bioavailability and short half-lives are the major factors which limit the pharmaceutical significance and therapeutic feasibility of these agents. In recent decades, nanotechnology-based delivery systems have gained remarkable attention of the researchers to mitigate the pharmaceutical issues related to the antipsychotic therapies and to optimize their oral drug delivery, therapeutic outcomes, and patient compliance. Oleh itu, the present review was aimed to summarize the available in vitro and in vivo evidences signifying the pharmaceutical importance of the advanced delivery systems in improving the aqueous solubility, transmembrane permeability, oral bioavailability and therapeutic outcome of the antipsychotic agents. © 2018 Bentham Science Publishers.},
nota = {dipetik oleh 2},
kata kunci = {Amisulpride, Amitriptyline, Haiwan, Antipsychotic Agents, Keresahan, Aripiprazole, Autisme, Bioavailability, Biological Availability, Bipolar Disorder, Buspirone, Kimia, Clonazepam, Clozapine, Kemurungan, Diazepam, Drug Delivery System, Drug Delivery Systems, Duloxetine, Half Life Time, Half-Life, Penjagaan Kesihatan, Manusia, Iloperidone, In Vitro Study, In Vivo Study, Mental Disease, Gangguan Mental, Midazolam, Nanotechnology, Neuroleptic Agent, Olanzapine, Patofisiologi, Kebolehtelapan, Physical Chemistry, Psychosis, Kaji semula, Risperidone, Skizofrenia, Solubility, Sulpiride, Hasil Rawatan, Venlafaxine, Ziprasidone},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Hnoonual, A; Thammachote, W; Tim-Aroon, T; Rojnueangnit, K; Hansakunachai, T; Sombuntham, T; Roongpraiwan, R; Vorachotekamjorn, J; Chuthapisith, J; Fucharoen, S; Wattanasirichaigoon, D; Ruangdaraganon, N; Limprasert, P; Jinawath, N

Analisis microarray kromosom dalam kohort populasi yang kurang diwakili mengenal pasti SERINC2 sebagai gen calon baru untuk gangguan spektrum autisme Artikel Jurnal

Laporan Saintifik, 7 (1), 2017, ISSN: 20452322, (dipetik oleh 6).

Abstrak | Pautan | BibTeX | Tag: Remaja, Autisme, Gangguan Spektrum Autisme, Anak-anak, Pemetaan Kromosom, Pemetaan Kromosom, Analisis Kohort, Kajian Kohort, Variasi Nombor Salin, Variasi Nombor Salinan DNA, Perempuan, Kecenderungan Genetik, Kecenderungan Genetik kepada Penyakit, Genetik, Manusia, Bayi, Lelaki, Protein Membran, Protein Membran, Analisis Mikroarray, Polimorfisme, Prasekolah, Kanak-kanak Prasekolah, Prosedur, SERINC2 Protein, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal

@artikel{Hnoual2017,
tajuk = {Analisis microarray kromosom dalam kohort populasi yang kurang diwakili mengenal pasti SERINC2 sebagai gen calon baru untuk gangguan spektrum autisme},
pengarang = {A Hnoonual dan W Thammachote dan T Tim-Aroon dan K Rojnueangnit dan T Hansakunachai dan T Sombuntham dan R Roongpraiwan dan J Worachotekamjorn dan J Chuthapisith dan S Fucharoen dan D Wattanasirichaigoon dan N Ruangdaraganon dan P Limprasert dan N Jinawath},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029864969&doi=10.1038/s41598-017-12317-3&rakan kongsi = 40&md5=3c1b6a0c064665aab8ace8e8f58c2b01},
doi = {10.1038/s41598-017-12317-3},
terbitan = {20452322},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {Laporan Saintifik},
isi padu = {7},
nombor = {1},
penerbit = {Kumpulan Penerbitan Alam},
abstrak = {Mikroarray kromosom (CMA) kini diiktiraf sebagai ujian genetik peringkat pertama untuk pengesanan variasi nombor salinan (CNV) pada pesakit dengan gangguan spektrum autisme (ASD). Matlamat kajian ini adalah untuk mengenal pasti ASD-CNV yang diketahui dan baru yang berkaitan dan untuk menilai hasil diagnostik CMA dalam pesakit Thai dengan ASD. Infinium CytoSNP-850K BeadChip telah digunakan untuk mengesan CNV dalam 114 Pesakit Thai terdiri daripada 68 pesakit ASD retrospektif (kumpulan 1) dengan penggunaan CMA sebagai ujian baris kedua dan 46 bakal pesakit ASD dan kelewatan perkembangan (kumpulan 2) dengan penggunaan CMA sebagai ujian peringkat pertama. Kami mengenal pasti 7 (6.1%) CNV patogenik dan 22 (19.3%) varian kepentingan klinikal yang tidak pasti (ANDA). Sejumlah 29 pesakit dengan CNV patogen dan VOUS ditemui di 22% (15/68) dan 30.4% (14/46) daripada pesakit dalam kumpulan 1 dan 2, masing-masing. Perbezaan frekuensi CNV yang dikesan antara 2 kumpulan tidak signifikan secara statistik (Chi kuasa dua = 1.02},
nota = {dipetik oleh 6},
kata kunci = {Remaja, Autisme, Gangguan Spektrum Autisme, Anak-anak, Pemetaan Kromosom, Pemetaan Kromosom, Analisis Kohort, Kajian Kohort, Variasi Nombor Salin, Variasi Nombor Salinan DNA, Perempuan, Kecenderungan Genetik, Kecenderungan Genetik kepada Penyakit, Genetik, Manusia, Bayi, Lelaki, Protein Membran, Protein Membran, Analisis Mikroarray, Polimorfisme, Prasekolah, Kanak-kanak Prasekolah, Prosedur, SERINC2 Protein, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Shuib, S; Saaid, N N; Zakaria, DENGAN; Ismail, J; Latiff, Abdul Z

Penduaan 17p11.2 (Sindrom Potocki-Lupski) pada kanak-kanak yang mengalami kelewatan perkembangan Artikel Jurnal

Jurnal Patologi Malaysia, 39 (1), hlm. 77-81, 2017, ISSN: 01268635, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Keabnormalan, Agarose, Artikel, Autisme, Gangguan Spektrum Autisme, Budaya Darah, Laporan kes, Anak-anak, Kromosom 17, Analisis Kromosom, Gangguan Kromosom, Penduaan Kromosom, Kromosom, Artikel Klinikal, Hibridisasi Genomik Perbandingan, Kelewatan Perkembangan, Elektroforesis, Perempuan, Pendarfluor, Pendarfluor dalam Hibridisasi Situ, Gen, Pengenalan Gen, Genetik, DNA genomik, Manusia, Hibridisasi In Situ, Kultur Limfosit, Analisis Mikroarray, Pelbagai, Sindrom Malformasi Pelbagai, berpasangan 17, Fenotip, Sindrom Potocki Lupski, Prasekolah, Kanak-kanak Prasekolah, Prosedur, Gen RAI1, Spektrofotometri ultraungu

@artikel{Shuib201777,
tajuk = {Penduaan 17p11.2 (Sindrom Potocki-Lupski) pada kanak-kanak yang mengalami kelewatan perkembangan},
pengarang = {S Shuib and N N Saaid and Z Zakaria and J Ismail and Z Abdul Latiff},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037028880&rakan kongsi = 40&md5=624b87d1e9ebac2d1bf66b4d30c0f6e9},
terbitan = {01268635},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {Jurnal Patologi Malaysia},
isi padu = {39},
nombor = {1},
halaman = {77-81},
penerbit = {Persatuan Pakar Patologi Malaysia},
abstrak = {Sindrom Potocki-Lupski (PTLS), juga dikenali sebagai sindrom duplikasi 17p11.2, trisomi 17p11.2 atau dup(17)(p11.2p11.2) sindrom, adalah gangguan perkembangan dan sindrom gen bersebelahan yang jarang menjejaskan 1 dalam 20,000 kelahiran hidup. Antara ciri utama pesakit tersebut ialah gangguan spektrum autisme, ketidakupayaan pembelajaran, kelewatan perkembangan, gangguan kurang perhatian, hipotonia bayi dan keabnormalan kardiovaskular. Kajian terdahulu menggunakan microarray mengenal pasti variasi dalam saiz dan takat kawasan pendua kromosom 17p11.2. Walau bagaimanapun, terdapat beberapa gen yang dianggap sebagai calon PTLS termasuk RAI1, SREBF1, DRG2, LLGL1, SHMT1 dan ZFP179. Dalam laporan ini, kami menyiasat kes seorang kanak-kanak perempuan berumur 3 tahun yang mengalami kelewatan perkembangan. Analisis kromosomnya menunjukkan karyotype normal (46,XX). Analisis menggunakan tatasusunan CGH (4X44 K, Agilent USA) mengenal pasti pertindihan ~4.2 Mb de novo dalam kromosom 17p11.2. Hasilnya disahkan oleh hibridisasi in situ pendarfluor (IKAN) menggunakan probe di kawasan PTLS kritikal. Laporan ini menunjukkan kepentingan microarray dan FISH dalam diagnosis PTLS. © 2017, Persatuan Pakar Patologi Malaysia. Hak cipta terpelihara.},
nota = {dipetik oleh 0},
kata kunci = {Keabnormalan, Agarose, Artikel, Autisme, Gangguan Spektrum Autisme, Budaya Darah, Laporan kes, Anak-anak, Kromosom 17, Analisis Kromosom, Gangguan Kromosom, Penduaan Kromosom, Kromosom, Artikel Klinikal, Hibridisasi Genomik Perbandingan, Kelewatan Perkembangan, Elektroforesis, Perempuan, Pendarfluor, Pendarfluor dalam Hibridisasi Situ, Gen, Pengenalan Gen, Genetik, DNA genomik, Manusia, Hibridisasi In Situ, Kultur Limfosit, Analisis Mikroarray, Pelbagai, Sindrom Malformasi Pelbagai, berpasangan 17, Fenotip, Sindrom Potocki Lupski, Prasekolah, Kanak-kanak Prasekolah, Prosedur, Gen RAI1, Spektrofotometri ultraungu},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Bhagat, V; Haque, M; Simbak, N B; Husain, R

Emotional regulation in autism spectrum disorders: A new proposed model for regulating emotions through parent education Artikel Jurnal

Journal of Global Pharma Technology, 9 (7), hlm. 32-43, 2017, ISSN: 09758542, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Adaptive Behavior, Amygdala, Autisme, Awareness, Kognisi, komorbiditi, Kerangka Konseptual, Cost Benefit Analysis, Pendidikan, Emosi, Emotional Disorder, Emotionality, Penjagaan Kesihatan, Health Promotion, Manusia, Impulsif, Belajar, Motivasi, Parent Education, Persepsi, Garis Panduan Amalan, Prefrontal Cortex, Kelaziman, Problem Behavior, Psychoeducation, Psychological Well Being, Kaji semula, Sex Difference, Kelakuan Sosial, Kognisi Sosial, Kecekapan Sosial, Social Learning

@artikel{Bhagat201732,
tajuk = {Emotional regulation in autism spectrum disorders: A new proposed model for regulating emotions through parent education},
pengarang = {V Bhagat and M Haque and N B Simbak and R Husain},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021786235&rakan kongsi = 40&md5=ece2d7c28018f0c4526810e08e314461},
terbitan = {09758542},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {Journal of Global Pharma Technology},
isi padu = {9},
nombor = {7},
halaman = {32-43},
penerbit = {Journal of Global Pharma Technology},
abstrak = {Autism spectrum disorders (ASD) boleh menjejaskan semua bidang kehidupan kanak-kanak. One of the areas of the behavioral spectrum need to be focused is affected. Oleh itu, the study is enthused in impaired emotional regulation (ER) affecting children with ASD. The significance of ER is related to that promoting adaptive behavior in children; indeed, disturbed ER in ASD children leads to emotional and behavioral problems. Commonly children with ASD lack adaptive ER strategies thus they react impulsively and inadequately to emotional stimuli thus it affects their psychological well-being. Though ER in ASD children is intrinsic the nurturing of these children with an understanding of ER can promote better psychological wellbeing. Oleh itu, study objectives to examine a) the impact of ASD on their ER b) the impact of ER on the psychological wellbeing of children with ASD c) To develop awareness among these parents regarding the impact of ER on the psychological wellbeing of their ASD child. d) To propose a new model of parental education about ER and its significance on psychological wellbeing of ASD children. This study takes a base on the keenly examined past evidence on impaired ER in ASD children and its impact on the psychological wellbeing. Proposal for aiding ER through parental education has introduced. The conclusion drawn in this study is that the intervention can be more promising with educating parents regarding ER, may help their child to gain maximum from therapeutic intervention. The new proposed model of intervention extends the further scope for research in this regard. © 2009-2017, JGPT.},
nota = {dipetik oleh 0},
kata kunci = {Adaptive Behavior, Amygdala, Autisme, Awareness, Kognisi, komorbiditi, Kerangka Konseptual, Cost Benefit Analysis, Pendidikan, Emosi, Emotional Disorder, Emotionality, Penjagaan Kesihatan, Health Promotion, Manusia, Impulsif, Belajar, Motivasi, Parent Education, Persepsi, Garis Panduan Amalan, Prefrontal Cortex, Kelaziman, Problem Behavior, Psychoeducation, Psychological Well Being, Kaji semula, Sex Difference, Kelakuan Sosial, Kognisi Sosial, Kecekapan Sosial, Social Learning},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Hakim, N H A; Majlis, B Y; Suzuki, H; Tsukahara, T

Neuron-specific splicing Artikel Jurnal

BioScience Trends, 11 (1), hlm. 16-22, 2017, ISSN: 18817815, (dipetik oleh 0).

Abstrak | Pautan | BibTeX | Tag: Alternative RNA Splicing, Alternative Splicing, Haiwan, Antibody Specificity, Biological, Biological Model, Penyakit, Genetik, Manusia, Metabolisme, Models, Nerve Cell, Neurons, Organ Specificity, RNA Splicing

@artikel{Hakim201716,
tajuk = {Neuron-specific splicing},
pengarang = {N H A Hakim and B Y Majlis and H Suzuki and T Tsukahara},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014435502&doi=10.5582%2fbst.2016.01169&rakan kongsi = 40&md5=8a5044dbf3b905fc2553520a048bcd59},
doi = {10.5582/bst.2016.01169},
terbitan = {18817815},
tahun = {2017},
tarikh = {2017-01-01},
jurnal = {BioScience Trends},
isi padu = {11},
nombor = {1},
halaman = {16-22},
penerbit = {International Advancement Center for Medicine and Health Research Co., Ltd.},
abstrak = {During pre-mRNA splicing events, introns are removed from the pre-mRNA, and the remaining exons are connected together to form a single continuous molecule. Alternative splicing is a common mechanism for the regulation of gene expression in eukaryotes. More than 90% of human genes are known to undergo alternative splicing. The most common type of alternative splicing is exon skipping, which is also known as cassette exon. Other known alternative splicing events include alternative 5' splice sites, alternative 3' splice sites, intron retention, and mutually exclusive exons. Alternative splicing events are controlled by regulatory proteins responsible for both positive and negative regulation. Dalam ulasan ini, we focus on neuronal splicing regulators and discuss several notable regulators in depth. Sebagai tambahan, we have also included an example of splicing regulation mediated by the RBFox protein family. Akhir kata, as previous studies have shown that a number of splicing factors are associated with neuronal diseases such as Alzheime's disease (AD) and Autism spectrum disorder (ASD), here we consider their importance in neuronal diseases wherein the underlying mechanisms have yet to be elucidated.},
nota = {dipetik oleh 0},
kata kunci = {Alternative RNA Splicing, Alternative Splicing, Haiwan, Antibody Specificity, Biological, Biological Model, Penyakit, Genetik, Manusia, Metabolisme, Models, Nerve Cell, Neurons, Organ Specificity, RNA Splicing},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Ooi, K L; Ong, Y S; Yakub, S A; Khan, T M

Meta-sintesis untuk mengasuh anak dengan autisme Artikel Jurnal

Penyakit dan Rawatan Neuropsychiatrik, 12 , hlm. 745-762, 2016, ISSN: 11766328, (dipetik oleh 44).

Abstrak | Pautan | BibTeX | Tag: Adaptasi, Artikel, Sikap Terhadap Kesihatan, Sikap Penyakit Mental, Autisme, Penjagaan Kanak-kanak, Hubungan Ibu Bapa Anak, Zaman kanak-kanak, Keluarga, Penjagaan Berpusatkan Keluarga, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Pendidikan Kesihatan, Manusia, Sikap Ibu Bapa, Tekanan Ibu Bapa, Kualiti hidup, Aspek Sosial, Kajian Sistematik, Kesejahteraan

@artikel{Ooi2016745,
tajuk = {Meta-sintesis untuk mengasuh anak dengan autisme},
pengarang = {K L Ooi dan Y S Ong dan S A Jacob dan T M Khan},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-84962625349&doi=10.2147/NDT.S100634&rakan kongsi = 40&md5 = 48b432dc361f8f3c373ed3b481e01e4c},
doi = {10.2147/NDT.S100634},
terbitan = {11766328},
tahun = {2016},
tarikh = {2016-01-01},
jurnal = {Penyakit dan Rawatan Neuropsychiatrik},
isi padu = {12},
halaman = {745-762},
penerbit = {Dove Medical Press Ltd.},
abstrak = {Latar belakang: Sifat autisme seumur hidup pada seorang anak mempunyai implikasi yang mendalam terhadap ibu bapa kerana mereka menghadapi pelbagai cabaran dan akibat emosi dalam membesarkan anak. Tujuan meta-sintesis ini adalah untuk meneroka perspektif ibu bapa dalam membesarkan anak dengan autisme pada zaman kanak-kanak untuk mendapatkan gambaran mengenai penyesuaian dan kepercayaan ibu bapa terhadap autisme, pengalaman keluarga dan sosial mereka, serta persepsi mereka terhadap perkhidmatan kesihatan dan pendidikan. Kaedah: Pencarian sistematik enam pangkalan data (PubMed, ASAS, PsikInfo, Daftar Pusat Percubaan Terkawal Cochrane, Pangkalan Data Cochrane dari Ulasan Sistematik, dan Pangkalan Data Abstrak Ulasan Kesan [BERANI]) dijalankan dari awal hingga September 30, 2014. Artikel Inggeris penuh teks kajian kualitatif yang menggambarkan persepsi ibu bapa berkaitan dengan penjagaan anak-anak yang lebih muda dari 12 berumur tahun dan didiagnosis dengan gangguan autisme sahaja. Keputusan: Sejumlah 50 artikel yang layak dinilai dan dianalisis, mengenal pasti empat tema teras merangkumi semua pemikiran, emosi, dan pengalaman yang biasa dinyatakan oleh ibu bapa: 1) Ibu Bapa, 2) Kesan kepada Keluarga, 3) Impak sosial, dan 4) Perkhidmatan Kesihatan dan Pendidikan. Hasil kajian mendapati ibu bapa yang mempunyai anak dengan autisme mengalami pelbagai cabaran dalam aspek penjagaan yang berbeza, memberi kesan kepada tekanan dan penyesuaian ibu bapa. Kesimpulannya: Penyediaan penjagaan kesihatan harus berpusatkan keluarga, menangani dan menyokong keperluan seisi keluarga dan bukan hanya anak yang terkena, untuk memastikan kesejahteraan dan kualiti hidup keluarga dalam menghadapi diagnosis autisme. © 2016 Ooi et al.},
nota = {dipetik oleh 44},
kata kunci = {Adaptasi, Artikel, Sikap Terhadap Kesihatan, Sikap Penyakit Mental, Autisme, Penjagaan Kanak-kanak, Hubungan Ibu Bapa Anak, Zaman kanak-kanak, Keluarga, Penjagaan Berpusatkan Keluarga, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Pendidikan Kesihatan, Manusia, Sikap Ibu Bapa, Tekanan Ibu Bapa, Kualiti hidup, Aspek Sosial, Kajian Sistematik, Kesejahteraan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Sheppard, E; Pillai, D; Wong, G T -L; Panggil, D; Mitchell, P

How Easy is it to Read the Minds of People with Autism Spectrum Disorder? Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 46 (4), hlm. 1247-1254, 2016, ISSN: 01623257, (dipetik oleh 37).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Autisme, Gangguan Spektrum Autisme, Membuat keputusan, Emosi, Ekspresi wajah, Perempuan, Manusia, Lelaki, Kesihatan mental, Perhubungan tanpa percakapan, Patofisiologi, Jurnal Keutamaan, Psikologi, Video Recording, Dewasa Muda

Gallagher, D; Voronova, A; Zander, M A; Cancun, G I; Bramall, A; Krause, M P; Abad, C; Tekin, M; Neilsen, P M; Callen, D F; Scherer, S W; Pembunuh, G M; Kaplan, D R; Walz, K; Miller, F D

Ankrd11 adalah pengatur kromatin yang terlibat dalam autisme yang penting untuk perkembangan saraf Artikel Jurnal

Sel Perkembangan, 32 (1), hlm. 31-42, 2015, ISSN: 15345807, (dipetik oleh 52).

Abstrak | Pautan | BibTeX | Tag: Asetilasi, Tingkah Laku Haiwan, Sel Haiwan, Haiwan, Protein Ankrd11, Ankyrin, Domain Ulangan Ankyrin yang Mengandungi Protein 11, Artikel, Autisme, Gangguan Spektrum Autisme, Kelakuan, Penanda Biologi, Meletup, Budaya Sel Otak, Kultur sel, Pembezaan Sel, Percambahan Sel, Sel, Kimia, Kromatin, Immunoprecipitation Chromatin, Berbudaya, Protein Mengikat DNA, Microarray DNA, Protein Pengikat DNA, Aktiviti Enzim, Perempuan, Gen, Profil Ekspresi Gen, Penyasaran Gen, Genetik, Histone, Asetilasi Histone, Histone Acetyltransferase, Histone Deacetylase, Histone Deacetylase 3, Deacetylases Histone, Histones, Manusia, Sel Manusia, Imunoprecipitasi, Utusan, Messenger RNA, Metabolisme, Tikus, Tetikus, Murinae, Mus, Pembezaan Sel Saraf, Pembangunan Sistem Saraf, Neurogenesis, Bukan Manusia, Analisis Urutan Array Oligonukleotida, Patologi, Fenotip, Fisiologi, Titik Mutasi, Pasca Terjemahan, Jurnal Keutamaan, Ekspresi Protein, Pemprosesan Protein, Tindak balas Rantai Polimerase Masa Nyata, Tindak balas Rantai Polimerase Transkrip terbalik, Reaksi Rantai Polimerase Transkripsi Berbalik, RNA, Kecil Mengganggu, RNA Mengganggu Kecil, Dadah yang tidak dikelaskan, Barat, Blotting Barat

@artikel{Gallagher201531,
tajuk = {Ankrd11 adalah pengatur kromatin yang terlibat dalam autisme yang penting untuk perkembangan saraf},
pengarang = {D Gallagher dan A Voronova dan M A Zander dan G I Cancino dan A Bramall dan M P Krause dan C Abad dan M Tekin dan P M Neilsen dan D F Callen dan S W Scherer dan G M Keller dan D R Kaplan dan K Walz dan F D Miller},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-84922343890&doi = 10.1016% 2fj.devcel.2014.11.031&rakan kongsi = 40&md5 = ad7b8bd3ead790f092e1d8a276d4f25c},
doi = {10.1016/j.devcel.2014.11.031},
terbitan = {15345807},
tahun = {2015},
tarikh = {2015-01-01},
jurnal = {Sel Perkembangan},
isi padu = {32},
nombor = {1},
halaman = {31-42},
penerbit = {Akhbar Sel},
abstrak = {Ankrd11 adalah pengatur kromatin yang berpotensi terlibat dalam perkembangan saraf dan gangguan spektrum autisme (ASD) tanpa fungsi yang diketahui di otak. Di sini, kami menunjukkan bahawa pengurangan Ankrd11 dalam mengembangkan prekursor saraf kortikal manusia atau manusia menyebabkan penurunan percambahan, neurogenesis berkurang, dan kedudukan neuron yang tidak betul. Fenotip selular yang serupa dan tingkah laku seperti ASD yang menyimpang diperhatikan pada tikus Yoda yang membawa mutasi titik dalam domain pengikat HDAC Ankrd11. Selaras dengan peranan untuk Ankrd11 dalam asetilasi histon, Ankrd11 dikaitkan dengan kromatin dan colocalized dengan HDAC3, dan ungkapan dan asetilasi histon gen sasaran Ankrd11 diubah pada pendahulu saraf Yoda. Lebih-lebih lagi, penurunan proliferasi prekursor yang dimediasi oleh Ankrd11 berjaya diselamatkan dengan menghalang aktiviti histon asetiltransferase atau menyatakan HDAC3. Oleh itu, Ankrd11 adalah pengatur kromatin penting yang mengawal asetilasi histon dan ekspresi gen semasa perkembangan saraf, sehingga memberikan penjelasan yang mungkin untuk kaitannya dengan disfungsi kognitif dan ASD. © 2015 Elsevier Inc.},
nota = {dipetik oleh 52},
kata kunci = {Asetilasi, Tingkah Laku Haiwan, Sel Haiwan, Haiwan, Protein Ankrd11, Ankyrin, Domain Ulangan Ankyrin yang Mengandungi Protein 11, Artikel, Autisme, Gangguan Spektrum Autisme, Kelakuan, Penanda Biologi, Meletup, Budaya Sel Otak, Kultur sel, Pembezaan Sel, Percambahan Sel, Sel, Kimia, Kromatin, Immunoprecipitation Chromatin, Berbudaya, Protein Mengikat DNA, Microarray DNA, Protein Pengikat DNA, Aktiviti Enzim, Perempuan, Gen, Profil Ekspresi Gen, Penyasaran Gen, Genetik, Histone, Asetilasi Histone, Histone Acetyltransferase, Histone Deacetylase, Histone Deacetylase 3, Deacetylases Histone, Histones, Manusia, Sel Manusia, Imunoprecipitasi, Utusan, Messenger RNA, Metabolisme, Tikus, Tetikus, Murinae, Mus, Pembezaan Sel Saraf, Pembangunan Sistem Saraf, Neurogenesis, Bukan Manusia, Analisis Urutan Array Oligonukleotida, Patologi, Fenotip, Fisiologi, Titik Mutasi, Pasca Terjemahan, Jurnal Keutamaan, Ekspresi Protein, Pemprosesan Protein, Tindak balas Rantai Polimerase Masa Nyata, Tindak balas Rantai Polimerase Transkrip terbalik, Reaksi Rantai Polimerase Transkripsi Berbalik, RNA, Kecil Mengganggu, RNA Mengganggu Kecil, Dadah yang tidak dikelaskan, Barat, Blotting Barat},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Haque, S; Haque, M

Terapi seni dan autisme Artikel Jurnal

Asian Journal of Pharmaceutical and Clinical Research, 8 (6), hlm. 202-203, 2015, ISSN: 09742441, (dipetik oleh 0).

Pautan | BibTeX | Tag: Terapi Seni, Artikel, Autisme, Tingkah Laku Kanak-kanak, Manusia, Perhubungan Manusia, Komunikasi Interpersonal, Perhubungan tanpa percakapan, Interaksi Sosial

Alwi, N; Harun, D; Leonard, J H

Clinical application of sensory integration therapy for children with autism Artikel Jurnal

Egyptian Journal of Medical Human Genetics, 16 (4), hlm. 393-394, 2015, ISSN: 11108630, (dipetik oleh 1).

Pautan | BibTeX | Tag: Autisme, Keterukan Penyakit, Groups by Age, Manusia, Surat, Motor Performance, Penilaian Hasil, Sensorimotor Integration, Terapi, Therapy Effect, Treatment Indication, Treatment Response

Khowaja, K; Salim, S S

Heuristics to evaluate interactive systems for children with Autism Spectrum Disorder (ASD) Artikel Jurnal

PLoS SATU, 10 (7), 2015, ISSN: 19326203, (dipetik oleh 12).

Abstrak | Pautan | BibTeX | Tag: Dewasa, Artikel, Autisme, Gangguan Spektrum Autisme, Pangkalan Data Bibliografi, Anak-anak, Computer Interface, Program komputer, Kajian Terkawal, Evaluation Study, Perempuan, Heuristics, Manusia, Information System, Interactive System, Interrater Reliability, Lelaki, Garis Panduan Amalan, Soal selidik, Software, Tinjauan

@artikel{Khowaja2015,
tajuk = {Heuristics to evaluate interactive systems for children with Autism Spectrum Disorder (ASD)},
pengarang = {K Khowaja dan S S Salim},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941313427&doi=10.1371/journal.pone.0132187&rakan kongsi = 40&md5=60f3ee4a32fd71be4b842755a58527cf},
doi = {10.1371/jurnal.pone.0132187},
terbitan = {19326203},
tahun = {2015},
tarikh = {2015-01-01},
jurnal = {PLoS SATU},
isi padu = {10},
nombor = {7},
penerbit = {Perpustakaan Awam Sains},
abstrak = {Dalam kertas ini, we adapted and expanded a set of guidelines, also known as heuristics, to evaluate the usability of software to now be appropriate for software aimed at children with autism spectrum disorder (ASD). We started from the heuristics developed by Nielsen in 1990 and developed a modified set of 15 heuristics. The first 5 heuristics of this set are the same as those of the original Nielsen set, the next 5 heuristics are improved versions of Nielsen's, whereas the last 5 heuristics are new. We present two evaluation studies of our new heuristics. In the first, two groups compared Nielsen's set with the modified set of heuristics, with each group evaluating two interactive systems. The Nielsen's heuristics were assigned to the control group while the experimental group was given the modified set of heuristics, and a statistical analysis was conducted to determine the effectiveness of the modified set, the contribution of 5 new heuristics and the impact of 5 improved heuristics. The results show that the modified set is significantly more effective than the original, and we found a significant difference between the five improved heuristics and their corresponding heuristics in the original set. The five new heuristics are effective in problem identification using the modified set. The second study was conducted using a system which was developed to ascertain if the modified set was effective at identifying usability problems that could be fixed before the release of software. The post-study analysis revealed that the majority of the usability problems identified by the experts were fixed in the updated version of the system. © 2015 Khowaja, Salim.},
nota = {dipetik oleh 12},
kata kunci = {Dewasa, Artikel, Autisme, Gangguan Spektrum Autisme, Pangkalan Data Bibliografi, Anak-anak, Computer Interface, Program komputer, Kajian Terkawal, Evaluation Study, Perempuan, Heuristics, Manusia, Information System, Interactive System, Interrater Reliability, Lelaki, Garis Panduan Amalan, Soal selidik, Software, Tinjauan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Alwi, N; Harun, D; Abad, L

Multidisciplinary Parent Education for Caregivers of Children With Autism Spectrum Disorders (ASD): Implications for Clinical Practice Artikel Jurnal

Archives of Psychiatric Nursing, 29 (1), hlm. 5, 2015, ISSN: 08839417, (dipetik oleh 0).

Pautan | BibTeX | Tag: Autisme, Gangguan Spektrum Autisme, Pengasuh, Gangguan Perkembangan Kanak-kanak, Anak-anak, Manusia, Ibu bapa, Meresap

Batt, S; Acharya, U R; Adeli, H; Tenusu, G M; Adeli, A

Autisme: Cause factors, early diagnosis and therapies Artikel Jurnal

Reviews in the Neurosciences, 25 (6), hlm. 841-850, 2014, ISSN: 03341763, (dipetik oleh 52).

Abstrak | Pautan | BibTeX | Tag: 4 Aminobutyric Acid, Remaja, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Artikel, Teknologi Bantuan, Perhatian, Autisme, Gangguan Spektrum Autisme, Behaviour Therapy, Penanda Biologi, Otak, Gangguan Perkembangan Kanak-kanak, Anak-anak, Kognisi, Cystine, Gangguan Perkembangan, Penyakit, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emosi, Ekspresi wajah, Pengimejan Resonans Magnetik Berfungsi, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Manusia, Bayi, Komunikasi Interpersonal, Methionine, Keradangan Sistem Saraf, Neurobiology, Neurofeedback, Oxidative Stress, Meresap, Fisiologi, Kanak-kanak Prasekolah, Jurnal Keutamaan, Psychoeducation, Budak sekolah, Interaksi Sosial, Terapi ucapan, Realiti maya, Zonisamide

@artikel{Bhat2014841,
tajuk = {Autisme: Cause factors, early diagnosis and therapies},
pengarang = {S Bhat and U R Acharya and H Adeli and G M Bairy and A Adeli},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925284617&doi=10.1515%2frevneuro-2014-0056&rakan kongsi = 40&md5=caaa32e66af70e70ec325241d01564c9},
doi = {10.1515/revneuro-2014-0056},
terbitan = {03341763},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Reviews in the Neurosciences},
isi padu = {25},
nombor = {6},
halaman = {841-850},
penerbit = {Walter de Gruyter GmbH},
abstrak = {Gangguan spektrum autisme (ASD) is a complex neurobiological disorder characterized by neuropsychological and behavioral deficits. Cognitive impairment, lack of social skills, and stereotyped behavior are the major autistic symptoms, visible after a certain age. It is one of the fastest growing disabilities. Its current prevalence rate in the U.S. estimated by the Centers for Disease Control and Prevention is 1 dalam 68 births. The genetic and physiological structure of the brain is studied to determine the pathology of autism, but diagnosis of autism at an early age is challenging due to the existing phenotypic and etiological heterogeneity among ASD individuals. Volumetric and neuroimaging techniques are explored to elucidate the neuroanatomy of the ASD brain. Nuroanatomical, neurochemical, and neuroimaging biomarkers can help in the early diagnosis and treatment of ASD. This paper presents a review of the types of autism, etiologies, early detection, and treatment of ASD. © 2014 Walter de Gruyter GmbH.},
nota = {dipetik oleh 52},
kata kunci = {4 Aminobutyric Acid, Remaja, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Artikel, Teknologi Bantuan, Perhatian, Autisme, Gangguan Spektrum Autisme, Behaviour Therapy, Penanda Biologi, Otak, Gangguan Perkembangan Kanak-kanak, Anak-anak, Kognisi, Cystine, Gangguan Perkembangan, Penyakit, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emosi, Ekspresi wajah, Pengimejan Resonans Magnetik Berfungsi, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Manusia, Bayi, Komunikasi Interpersonal, Methionine, Keradangan Sistem Saraf, Neurobiology, Neurofeedback, Oxidative Stress, Meresap, Fisiologi, Kanak-kanak Prasekolah, Jurnal Keutamaan, Psychoeducation, Budak sekolah, Interaksi Sosial, Terapi ucapan, Realiti maya, Zonisamide},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Batt, S; Acharya, U R; Adeli, H; Tenusu, G M; Adeli, A

Automated diagnosis of autism: In search of a mathematical marker Artikel Jurnal

Reviews in the Neurosciences, 25 (6), hlm. 851-861, 2014, ISSN: 03341763, (dipetik oleh 34).

Abstrak | Pautan | BibTeX | Tag: Algoritma, Artikel, Autisme, Gangguan Spektrum Autisme, Automasi, Biological Model, Otak, Chaos Theory, Correlation Analysis, Detrended Fluctuation Analysis, Disease Marker, Electrode, Elektroencephalogram, Elektroensefalografi, Entropy, Fourier Transformation, Fractal Analysis, Frequency Domain Analysis, Manusia, Mathematical Analysis, Mathematical Marker, Mathematical Parameters, Models, Neurologic Disease, Neurological, Nonlinear Dynamics, Nonlinear System, Patofisiologi, Jurnal Keutamaan, Prosedur, Pemprosesan isyarat, Model Statistik, Masa, Time Frequency Analysis, Wavelet Analysis

@artikel{Bhat2014851,
tajuk = {Automated diagnosis of autism: In search of a mathematical marker},
pengarang = {S Bhat and U R Acharya and H Adeli and G M Bairy and A Adeli},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925286949&doi=10.1515%2frevneuro-2014-0036&rakan kongsi = 40&md5=04858a5c9860e9027e3113835ca2e11f},
doi = {10.1515/revneuro-2014-0036},
terbitan = {03341763},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Reviews in the Neurosciences},
isi padu = {25},
nombor = {6},
halaman = {851-861},
penerbit = {Walter de Gruyter GmbH},
abstrak = {Autism is a type of neurodevelopmental disorder affecting the memory, behavior, emotion, learning ability, and communication of an individual. An early detection of the abnormality, due to irregular processing in the brain, can be achieved using electroencephalograms (LIHAT). The variations in the EEG signals cannot be deciphered by mere visual inspection. Computer-aided diagnostic tools can be used to recognize the subtle and invisible information present in the irregular EEG pattern and diagnose autism. This paper presents a state-of-theart review of automated EEG-based diagnosis of autism. Various time domain, frequency domain, time-frequency domain, and nonlinear dynamics for the analysis of autistic EEG signals are described briefly. A focus of the review is the use of nonlinear dynamics and chaos theory to discover the mathematical biomarkers for the diagnosis of the autism analogous to biological markers. A combination of the time-frequency and nonlinear dynamic analysis is the most effective approach to characterize the nonstationary and chaotic physiological signals for the automated EEGbased diagnosis of autism spectrum disorder (ASD). The features extracted using these nonlinear methods can be used as mathematical markers to detect the early stage of autism and aid the clinicians in their diagnosis. This will expedite the administration of appropriate therapies to treat the disorder. © 2014 Walter de Gruyter GmbH.},
nota = {dipetik oleh 34},
kata kunci = {Algoritma, Artikel, Autisme, Gangguan Spektrum Autisme, Automasi, Biological Model, Otak, Chaos Theory, Correlation Analysis, Detrended Fluctuation Analysis, Disease Marker, Electrode, Elektroencephalogram, Elektroensefalografi, Entropy, Fourier Transformation, Fractal Analysis, Frequency Domain Analysis, Manusia, Mathematical Analysis, Mathematical Marker, Mathematical Parameters, Models, Neurologic Disease, Neurological, Nonlinear Dynamics, Nonlinear System, Patofisiologi, Jurnal Keutamaan, Prosedur, Pemprosesan isyarat, Model Statistik, Masa, Time Frequency Analysis, Wavelet Analysis},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Cassidy, S; Panggil, D; Mitchell, P; Kapten, P

Can adults with autism spectrum disorders infer what happened to someone from their emotional response? Artikel Jurnal

Penyelidikan Autisme, 7 (1), hlm. 112-123, 2014, ISSN: 19393792, (dipetik oleh 21).

Abstrak | Pautan | BibTeX | Tag: Ketepatan, Dewasa, Aged, Artikel, Sindrom Asperger, Perhatian, Autisme, Kelakuan, Cacao, Gangguan Perkembangan Kanak-kanak, Artikel Klinikal, Concept Formation, Kajian Terkawal, Deception, Discrimination (Psikologi), Emosi, Pergerakan Mata, Eye Tracking, Face Processing, Ekspresi wajah, Perempuan, Manusia, Interpersonal Relations, Lelaki, Pertengahan umur, Money, Meresap, Jurnal Keutamaan, Recipient, Recognition, Reference Values, Retrodictive Mindreading, Spontaneous Emotion Recognition, Theory of Mind, Video Recording, Dewasa Muda

@artikel{Cassidy2014112,
tajuk = {Can adults with autism spectrum disorders infer what happened to someone from their emotional response?},
pengarang = {S Cassidy and D Ropar and P Mitchell and P Chapman},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84894307909&doi=10.1002%2faur.1351&rakan kongsi = 40&md5=8c6736bc006e9eebde29427879d023c3},
doi = {10.1002/aur.1351},
terbitan = {19393792},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Penyelidikan Autisme},
isi padu = {7},
nombor = {1},
halaman = {112-123},
penerbit = {John Wiley and Sons Inc.},
abstrak = {Can adults with autism spectrum disorders (ASD) infer what happened to someone from their emotional response? Millikan has argued that in everyday life, others' emotions are most commonly used to work out the antecedents of behavior, an ability termed retrodictive mindreading. As those with ASD show difficulties interpreting others' emotions, we predicted that these individuals would have difficulty with retrodictive mindreading. Sixteen adults with high-functioning autism or Asperger's syndrome and 19 typically developing adults viewed 21 video clips of people reacting to one of three gifts (chocolate, monopoly money, or a homemade novelty) and then inferred what gift the recipient received and the emotion expressed by that person. Participants' eye movements were recorded while they viewed the videos. Results showed that participants with ASD were only less accurate when inferring who received a chocolate or homemade gift. This difficulty was not due to lack of understanding what emotions were appropriate in response to each gift, as both groups gave consistent gift and emotion inferences significantly above chance (genuine positive for chocolate and feigned positive for homemade). Those with ASD did not look significantly less to the eyes of faces in the videos, and looking to the eyes did not correlate with accuracy on the task. These results suggest that those with ASD are less accurate when retrodicting events involving recognition of genuine and feigned positive emotions, and challenge claims that lack of attention to the eyes causes emotion recognition difficulties in ASD. Autism Res 2014, 7: 112-123. © 2013 International Society for Autism Research, Berkala Wiley, Inc.},
nota = {dipetik oleh 21},
kata kunci = {Ketepatan, Dewasa, Aged, Artikel, Sindrom Asperger, Perhatian, Autisme, Kelakuan, Cacao, Gangguan Perkembangan Kanak-kanak, Artikel Klinikal, Concept Formation, Kajian Terkawal, Deception, Discrimination (Psikologi), Emosi, Pergerakan Mata, Eye Tracking, Face Processing, Ekspresi wajah, Perempuan, Manusia, Interpersonal Relations, Lelaki, Pertengahan umur, Money, Meresap, Jurnal Keutamaan, Recipient, Recognition, Reference Values, Retrodictive Mindreading, Spontaneous Emotion Recognition, Theory of Mind, Video Recording, Dewasa Muda},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Shobana, M; Saravanan, C

Comparative study on attitudes and psychological problems of mothers towards their children with developmental disability Artikel Jurnal

East Asian Archives of Psychiatry, 24 (1), hlm. 16-22, 2014, ISSN: 20789947, (dipetik oleh 6).

Abstrak | Pautan | BibTeX | Tag: Dewasa, Keresahan, Artikel, Attitude, Autisme, Gangguan Spektrum Autisme, Anak-anak, Kajian Perbandingan, Kemurungan, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Sindrom Down, Pendidikan, Perempuan, General Health Questionnaire 28, Home Care, Hostility, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kajian Klinikal Utama, Malaysia, Lelaki, Gangguan Mental, Mother Child Relation, Mothers, Named Inventories, Sikap Ibu Bapa, Parental Attitude Scale, Kelaziman, Psychological Well Being, Soal selidik, Skala penilaian, Budak sekolah, Social Disability

@artikel{Shobana201416,
tajuk = {Comparative study on attitudes and psychological problems of mothers towards their children with developmental disability},
pengarang = {M Shobana and C Saravanan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84898619897&rakan kongsi = 40&md5=e877e03b868d1a11ed8f859a33057d5d},
terbitan = {20789947},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {East Asian Archives of Psychiatry},
isi padu = {24},
nombor = {1},
halaman = {16-22},
penerbit = {Hong Kong Academy of Medicine Press},
abstrak = {Objektif: Parents' positive attitudes and psychological wellbeing play an important role in the development of the children with developmental disability. This study aimed to measure the prevalence of psychological problems among mothers of children with autism disorder, intellectual disability, and Down syndrome. The second aim was to assess the differences in mothers' attitudes and psychological problems among their children with intellectual disability, autism disorder, and Down syndrome. The third aim was to identify whether negative attitude was a predictor of psychological problems in these mothers. Kaedah: Dalam kajian ini, 112 mothers of children having mild and moderate levels of autism disorder, Sindrom Down, and intellectual disability were assessed using the Parental Attitude Scale and General Health Questionnaire-28. Keputusan: Secara keseluruhan, mothers of children with intellectual disability were found to have the most negative attitude towards their child. Mothers of children with autism disorder exhibited higher scores on somatic symptoms, kegelisahan, and social dysfunction when compared with their counterparts with Down syndrome and intellectual disability. Negative attitude was a significant predictor of psychological problems. Kesimpulannya: Parental attitudes and psychological problems would vary among mothers of children with different types of developmental disability. © 2014 Hong Kong College of Psychiatrists.},
nota = {dipetik oleh 6},
kata kunci = {Dewasa, Keresahan, Artikel, Attitude, Autisme, Gangguan Spektrum Autisme, Anak-anak, Kajian Perbandingan, Kemurungan, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Sindrom Down, Pendidikan, Perempuan, General Health Questionnaire 28, Home Care, Hostility, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kajian Klinikal Utama, Malaysia, Lelaki, Gangguan Mental, Mother Child Relation, Mothers, Named Inventories, Sikap Ibu Bapa, Parental Attitude Scale, Kelaziman, Psychological Well Being, Soal selidik, Skala penilaian, Budak sekolah, Social Disability},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Chen, B C; Rawi, Mohd R; Meinsma, R; Meijer, J; Hennekam, R C M; Kuilenburg, Van A B P

Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings Artikel Jurnal

Molecular Syndromology, 5 (6), hlm. 299-303, 2014, ISSN: 16618769, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Alanine, Artikel, Asymptomatic Disease, Autisme, Autosomal Recessive Disorder, Laporan kes, Cerebellum Atrophy, Anak-anak, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Keterukan Penyakit, DPYD Gene, Eye Malformation, Perempuan, Gen, Gene Mutation, Homozygosity, Manusia, Kemerosotan Intelektual, Orang Malaysia, Lelaki, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Kanak-kanak Prasekolah, Pyrimidine, Pyrimidine Metabolism, Budak sekolah, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil

@artikel{Chen2014299,
tajuk = {Dihydropyrimidine dehydrogenase deficiency in two Malaysian siblings with abnormal MRI findings},
pengarang = {B C Chen and R Mohd Rawi and R Meinsma and J Meijer and R C M Hennekam and A B P Van Kuilenburg},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919783242&doi=10.1159%2f000366074&rakan kongsi = 40&md5=1ebfb9aedb7cb64e3423811b41b6aa7c},
doi = {10.1159/000366074},
terbitan = {16618769},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Molecular Syndromology},
isi padu = {5},
nombor = {6},
halaman = {299-303},
penerbit = {S. Karger AG},
abstrak = {Dihydropyrimidine dehydrogenase (DPD) deficiency is an autosomal recessive disorder of the pyrimidine metabolism. Deficiency of this enzyme leads to an accumulation of thymine and uracil and a deficiency of metabolites distal to the catabolic enzyme. The disorder presents with a wide clinical spectrum, ranging from asymptomatic to severe neurological manifestations, termasuk kecacatan intelektual, seizures, microcephaly, autistic behavior, and eye abnormalities. Di sini, we report on an 11-year-old Malaysian girl and her 6-year-old brother with DPD deficiency who presented with intellectual disability, microcephaly, and hypotonia. Brain MRI scans showed generalized cerebral and cerebellar atrophy and callosal body dysgenesis in the boy. Urine analysis showed strongly elevated levels of uracil in the girl and boy (571 dan 578 mmol/mol creatinine, masing-masing) and thymine (425 dan 427 mmol/mol creatinine, masing-masing). Sequence analysis of the DPYD gene showed that both siblings were homozygous for the mutation c.1651G>A (pAla551Thr). © 2014 S. Karger AG, Basel.},
nota = {dipetik oleh 4},
kata kunci = {Alanine, Artikel, Asymptomatic Disease, Autisme, Autosomal Recessive Disorder, Laporan kes, Cerebellum Atrophy, Anak-anak, Creatinine, Dihydropyrimidine Dehydrogenase, Dihydropyrimidine Dehydrogenase Deficiency, Keterukan Penyakit, DPYD Gene, Eye Malformation, Perempuan, Gen, Gene Mutation, Homozygosity, Manusia, Kemerosotan Intelektual, Orang Malaysia, Lelaki, Microcephaly, Muscle Hypotonia, Nuclear Magnetic Resonance Imaging, Kanak-kanak Prasekolah, Pyrimidine, Pyrimidine Metabolism, Budak sekolah, Seizure, Sequence Analysis, Sibling, Threonine, Thymine, Uracil},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Tidak juga, Z M; Yusof, S N; Ghazi, H F; Ialah, Z M

Does Bisphenol A contribute to autism spectrum disorder? Artikel Jurnal

Current Topics in Toxicology, 10 , hlm. 63-70, 2014, ISSN: 09728228, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: 4' Isopropylidenediphenol, Artikel, Autisme, Behaviour Change, Persatuan Penyakit, Faktor Persekitaran, First Pass Effect, Manusia, Population, Pregnancy, Prenatal Period

@artikel{Nor201463,
tajuk = {Does Bisphenol A contribute to autism spectrum disorder?},
pengarang = {Z M Nor and S N Yusof and H F Ghazi and Z M Isa},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939185210&rakan kongsi = 40&md5=57e7aabc3aa2ec1ab51747608ab6a9b2},
terbitan = {09728228},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {Current Topics in Toxicology},
isi padu = {10},
halaman = {63-70},
penerbit = {Research Trends},
abstrak = {Gangguan Spektrum Autisme (ASD) includes a range of conditions classified as neurodevelopmental disorders that have an onset from infancy. Multiple factors have been identified as causes for the autism spectrum disorder; namun begitu, the cascade of the disease is still not clearly defined. An increasing number of cases have been reported globally, for instance in US, UK, Canada and Australia. Environmental factors were suspected to be one of the causes. Bisphenol A (BPA) is an Endocrine Disruptor Compound (EDC) and used primarily as a monomer for the production of polycarbonate and epoxy resins, especially in feeding bottles for infants. Ongoing discussions are currently in progress on the reported low-dose effects of BPA, particularly its neurodevelopmental and behavioural effects. Many countries have banned the usage of BPA due to its harmful effects on children. This review aims at presenting an overview of the association between exposure to BPA and the neurobehavioural changes it triggers in children. Articles were obtained from the Science Direct and ProQuest search engines. The keywords used in the search were 'BPA' or 'bisphenol A' and áutism'. Fourty-seven articles were shortlisted, of which only five that fulfilled the requisite criteria were selected for review. All of them were cohort studies. Secara keseluruhan, an association has been established between prenatal and childhood exposure to BPA and neurobehavioural changes. The exposure during pregnancy was observed to have a greater impact on children. Earlier exposure during the prenatal period resulted in stronger associations. Walau bagaimanapun, no association was found between BPA concentration of the child and neurobehavioural outcomes.},
nota = {dipetik oleh 1},
kata kunci = {4' Isopropylidenediphenol, Artikel, Autisme, Behaviour Change, Persatuan Penyakit, Faktor Persekitaran, First Pass Effect, Manusia, Population, Pregnancy, Prenatal Period},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Brett, M; McPherson, J; Vokal, Z J; Lai, A; Tan, E -S; Ng, Saya; Ong, L -C; Cham, B; Tan, P; Bunga mawar, S; Tan, DAN -C

Massively parallel sequencing of patients with intellectual disability, congenital anomalies and/or autism spectrum disorders with a targeted gene panel Artikel Jurnal

PLoS SATU, 9 (4), 2014, ISSN: 19326203, (dipetik oleh 20).

Abstrak | Pautan | BibTeX | Tag: Artikel, ATRX Gene, Autisme, Gangguan Spektrum Autisme, Anak-anak, Artikel Klinikal, Congenital Abnormalities, Congenital Malformation, Kajian Terkawal, Diagnostic Test, DNA Mutational Analysis, Perempuan, Gen, Profil Ekspresi Gen, Gene Mutation, Penyasaran Gen, Persatuan Genetik, Genetic Association Studies, Genetic Disorder, Genetic Variability, Genetic Variation, Genetik, Genome-Wide Association Study, High Throughput Sequencing, High-Throughput Nucleotide Sequencing, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Karyotype, L1CAM Gene, Lelaki, Mutation, Nonsense Mutation, Nucleotide Sequence, Fenotip, Polimorfisme, RNA Splice Sites, RNA Splicing, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal

@artikel{Brett2014,
tajuk = {Massively parallel sequencing of patients with intellectual disability, congenital anomalies and/or autism spectrum disorders with a targeted gene panel},
pengarang = {M Brett and J McPherson and Z J Zang and A Lai and E -S Tan and I Ng and L -C Ong and B Cham and P Tan and S Rozen and E -C Tan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84898625023&doi=10.1371/journal.pone.0093409&rakan kongsi = 40&md5=f673e204a009bf84de81ea69dcd026db},
doi = {10.1371/jurnal.pone.0093409},
terbitan = {19326203},
tahun = {2014},
tarikh = {2014-01-01},
jurnal = {PLoS SATU},
isi padu = {9},
nombor = {4},
penerbit = {Perpustakaan Awam Sains},
abstrak = {Developmental delay and/or intellectual disability (DD/ID) affects 1-3% of all children. At least half of these are thought to have a genetic etiology. Recent studies have shown that massively parallel sequencing (MPS) using a targeted gene panel is particularly suited for diagnostic testing for genetically heterogeneous conditions. We report on our experiences with using massively parallel sequencing of a targeted gene panel of 355 genes for investigating the genetic etiology of eight patients with a wide range of phenotypes including DD/ID, congenital anomalies and/or autism spectrum disorder. Targeted sequence enrichment was performed using the Agilent SureSelect Target Enrichment Kit and sequenced on the Illumina HiSeq2000 using paired-end reads. For all eight patients, 81-84% of the targeted regions achieved read depths of at least 20×, with average read depths overlapping targets ranging from 322 × to 798 ×. Causative variants were successfully identified in two of the eight patients: a nonsense mutation in the ATRX gene and a canonical splice site mutation in the L1CAM gene. In a third patient, a canonical splice site variant in the USP9X gene could likely explain all or some of her clinical phenotypes. These results confirm the value of targeted MPS for investigating DD/ID in children for diagnostic purposes. Walau bagaimanapun, targeted gene MPS was less likely to provide a genetic diagnosis for children whose phenotype includes autism. © 2014 Brett et al.},
nota = {dipetik oleh 20},
kata kunci = {Artikel, ATRX Gene, Autisme, Gangguan Spektrum Autisme, Anak-anak, Artikel Klinikal, Congenital Abnormalities, Congenital Malformation, Kajian Terkawal, Diagnostic Test, DNA Mutational Analysis, Perempuan, Gen, Profil Ekspresi Gen, Gene Mutation, Penyasaran Gen, Persatuan Genetik, Genetic Association Studies, Genetic Disorder, Genetic Variability, Genetic Variation, Genetik, Genome-Wide Association Study, High Throughput Sequencing, High-Throughput Nucleotide Sequencing, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Karyotype, L1CAM Gene, Lelaki, Mutation, Nonsense Mutation, Nucleotide Sequence, Fenotip, Polimorfisme, RNA Splice Sites, RNA Splicing, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Freeth, M; Sheppard, E; Ramachandran, R; Milne, E

Perbandingan silang budaya ciri autistik di UK, India and Malaysia Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 43 (11), hlm. 2569-2583, 2013, ISSN: 01623257, (dipetik oleh 39).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Kumpulan Leluhur Benua Asia, Perhatian, Autisme, Gangguan Spektrum Autisme, Kuantiti Spektrum Autisme, Kemahiran komunikasi, Kajian Perbandingan, Perbandingan Merentas Budaya, Faktor Budaya, Etnik, Perempuan, Great Britain, Manusia, Eksperimen Manusia, Khayalan, India, Orang India, Malaysia, Lelaki, Keperibadian, Fenotip, Pelajar Pascasiswazah, Jurnal Keutamaan, Psikometri, Soal selidik, Faktor Seks, Penyesuaian Sosial, Spektrum, Pelajar, Pelajar Prasiswazah, United Kingdom, Dewasa Muda

@artikel{Freeth20132569,
tajuk = {Perbandingan silang budaya ciri autistik di UK, India and Malaysia},
pengarang = {M Freeth dan E Sheppard dan R Ramachandran dan E Milne},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-84886802970&doi = 10.1007% 2fs10803-013-1808-9&rakan kongsi = 40&md5 = d8acde51c0626be3862facc1d6bc493c},
doi = {10.1007/s10803-013-1808-9},
terbitan = {01623257},
tahun = {2013},
tarikh = {2013-01-01},
jurnal = {Jurnal Autisme dan Gangguan Perkembangan},
isi padu = {43},
nombor = {11},
halaman = {2569-2583},
abstrak = {Gangguan autisme dikenali secara meluas di seluruh dunia. Walau bagaimanapun, kriteria diagnostik dan teori autisme didasarkan pada penyelidikan yang kebanyakannya dilakukan dalam budaya Barat. Di sini kita membandingkan ekspresi sifat autistik dalam sampel individu neurotipikal dari satu budaya Barat (UK) dan dua budaya Timur (India and Malaysia), menggunakan Autisme-spektrum Quotient (AQ) untuk mengenal pasti kemungkinan perbezaan budaya dalam penyataan sifat autistik. Tingkah laku yang berkaitan dengan sifat autistik dilaporkan pada tahap yang lebih besar dalam budaya Timur daripada budaya Barat. Lelaki mendapat markah lebih tinggi daripada pelajar perempuan dan pelajar sains mendapat markah lebih tinggi daripada pelajar bukan sains dalam setiap budaya. Pelajar India mendapat markah lebih tinggi daripada kedua-dua kumpulan lain pada sub-skala Imaginasi, Pelajar Malaysia mendapat markah lebih tinggi daripada kedua-dua kumpulan lain pada sub skala Attention Switching. Struktur faktor asas AQ untuk setiap populasi diperoleh dan dibincangkan. © 2013 Springer Science + Business Media New York.},
nota = {dipetik oleh 39},
kata kunci = {Remaja, Dewasa, Artikel, Kumpulan Leluhur Benua Asia, Perhatian, Autisme, Gangguan Spektrum Autisme, Kuantiti Spektrum Autisme, Kemahiran komunikasi, Kajian Perbandingan, Perbandingan Merentas Budaya, Faktor Budaya, Etnik, Perempuan, Great Britain, Manusia, Eksperimen Manusia, Khayalan, India, Orang India, Malaysia, Lelaki, Keperibadian, Fenotip, Pelajar Pascasiswazah, Jurnal Keutamaan, Psikometri, Soal selidik, Faktor Seks, Penyesuaian Sosial, Spektrum, Pelajar, Pelajar Prasiswazah, United Kingdom, Dewasa Muda},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Khowaja, K; Salim, S S

Kajian sistematik mengenai strategi dan intervensi berasaskan komputer (CBI) untuk membaca pemahaman kanak-kanak dengan autisme Artikel Jurnal

Penyelidikan dalam Gangguan Spektrum Autisme, 7 (9), hlm. 1111-1121, 2013, ISSN: 17509467, (dipetik oleh 28).

Abstrak | Pautan | BibTeX | Tag: Perhatian, Autisme, Pangkalan Data Bibliografi, Anak-anak, Keberkesanan Klinikal, Pemerhatian Klinikal, Kognisi, Kefahaman, Terapi Berbantukan Komputer, Intervensi Berasaskan Komputer, Ingatan Eksplisit, Manusia, Belajar, Linguistik, Motivasi, Multimedia, Reka Bentuk Posttest Pretest, Jurnal Keutamaan, Membaca, Pemahaman bacaan, Kaji semula, Kajian Sistematik, Hasil Rawatan

@artikel{Khowaja20131111,
tajuk = {Kajian sistematik mengenai strategi dan intervensi berasaskan komputer (CBI) untuk membaca pemahaman kanak-kanak dengan autisme},
pengarang = {K Khowaja dan S S Salim},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-84879609907&doi=10.1016/j.rasd.2013.05.009&rakan kongsi = 40&md5 = 6ba3e9315ee8b3cecb6248b97198313d},
doi = {10.1016/j.rasd.2013.05.009},
terbitan = {17509467},
tahun = {2013},
tarikh = {2013-01-01},
jurnal = {Penyelidikan dalam Gangguan Spektrum Autisme},
isi padu = {7},
nombor = {9},
halaman = {1111-1121},
abstrak = {Makalah ini membentangkan tinjauan sistematik mengenai kajian yang diterbitkan yang berkaitan mengenai pemahaman membaca untuk kanak-kanak dengan autisme, memberi tumpuan kepada arahan perbendaharaan kata dan pengajaran pemahaman teks dari tahun 2000 ke 2011. Kajian sistematik ini cuba menangani tiga persoalan kajian khusus: strategi pengajaran kosa kata dan arahan pemahaman teks yang digunakan, campur tangan berasaskan komputer (CBI) digunakan atau dikembangkan semasa belajar, dan keberkesanan penggunaan CBI untuk mengajar kanak-kanak dengan autisme. Terdapat lima strategi pengajaran kosa kata dan tujuh strategi pengajaran pemahaman teks. Hasil menunjukkan bahawa dua strategi pengajaran kosa kata, kaedah multimedia dan arahan eksplisit didapati lebih biasa digunakan daripada tiga kaedah lain. Pada nota yang sama, strategi menjawab soalan pengajaran pemahaman teks didapati digunakan lebih kerap daripada enam yang lain. Hasilnya juga menunjukkan bahawa kanak-kanak dengan autisme dapat memanfaatkan strategi pemahaman membaca dan penggunaan CBI sebagai kaedah pengajaran untuk pemahaman membaca meningkatkan pembelajaran anak-anak. Ini jelas dilihat dari prestasi kanak-kanak antara ujian pra dan ujian pasca kajian di mana CBI digunakan. Walau bagaimanapun, kerana heterogenitas peserta, ini tidak selalu berlaku; beberapa kajian melaporkan tiada peningkatan dalam pembelajaran kanak-kanak dengan autisme. © 2013 Elsevier Ltd.. Hak cipta terpelihara.},
nota = {dipetik oleh 28},
kata kunci = {Perhatian, Autisme, Pangkalan Data Bibliografi, Anak-anak, Keberkesanan Klinikal, Pemerhatian Klinikal, Kognisi, Kefahaman, Terapi Berbantukan Komputer, Intervensi Berasaskan Komputer, Ingatan Eksplisit, Manusia, Belajar, Linguistik, Motivasi, Multimedia, Reka Bentuk Posttest Pretest, Jurnal Keutamaan, Membaca, Pemahaman bacaan, Kaji semula, Kajian Sistematik, Hasil Rawatan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Mousavizadeh, K; Askari, M; Arian, H; Gorjipour, F; Nikpour, A R; Fesyen biasa, M; Aryani, THE; Kamalidehghan, B; Maroof, H R; Houshmand, M

Association of human mtDNA mutations with autism in Iranian patients Artikel Jurnal

Journal of Research in Medical Sciences, 18 (10), hlm. 926, 2013, ISSN: 17351995, (dipetik oleh 2).

Pautan | BibTeX | Tag: Autisme, Artikel Klinikal, Kajian Terkawal, Gen, Gene Frequency, Gene Mutation, Gene Sequence, Persatuan Genetik, Risiko Genetik, Manusia, Surat, Mitochondrial DNA, Molecular Phylogeny, Patofisiologi, Titik Mutasi, Polymerase Chain Reaction

Selvaraj, J; Murugappan, M; Van, K; Yaacob, S

Classification of emotional states from electrocardiogram signals: A non-linear approach based on hurst Artikel Jurnal

BioMedical Engineering Online, 12 (1), 2013, ISSN: 1475925X, (dipetik oleh 42).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Aged, Artikel, Audio-Visual Stimulus, Autonomous Nervous Systems, Anak-anak, Ketepatan Pengelasan, Computer Based Training, Computer-Assisted, Electrocardiogram Signal, Electrocardiography, Emosi, Perempuan, Fuzzy K-nearest Neighbor, Higher-Order Statistic (HOS), Manusia, Kecacatan Intelektual, Sistem Komputer Interaktif, Metodologi, Pertengahan umur, Nonlinear Dynamics, Nonlinear System, Prosedur, Real Time Systems, Pemprosesan isyarat, Statistik, Dewasa Muda

@artikel{Selvaraj2013,
tajuk = {Classification of emotional states from electrocardiogram signals: A non-linear approach based on hurst},
pengarang = {J Selvaraj and M Murugappan and K Wan and S Yaacob},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879017985&doi=10.1186%2f1475-925X-12-44&rakan kongsi = 40&md5=18c5309ac9f3017f455480f1ff732a30},
doi = {10.1186/1475-925X-12-44},
terbitan = {1475925X},
tahun = {2013},
tarikh = {2013-01-01},
jurnal = {BioMedical Engineering Online},
isi padu = {12},
nombor = {1},
penerbit = {BioMed Central Ltd.},
abstrak = {Latar belakang: Identifying the emotional state is helpful in applications involving patients with autism and other intellectual disabilities; computer-based training, human computer interaction etc. Electrocardiogram (ECG) signals, being an activity of the autonomous nervous system (ANS), reflect the underlying true emotional state of a person. Walau bagaimanapun, the performance of various methods developed so far lacks accuracy, and more robust methods need to be developed to identify the emotional pattern associated with ECG signals.Methods: Emotional ECG data was obtained from sixty participants by inducing the six basic emotional states (happiness, sadness, fear, disgust, surprise and neutral) using audio-visual stimuli. The non-linear feature 'Hurst' was computed using Rescaled Range Statistics (RRS) and Finite Variance Scaling (FVS) methods. New Hurst features were proposed by combining the existing RRS and FVS methods with Higher Order Statistics (HOS). The features were then classified using four classifiers - Bayesian Classifier, Regression Tree, K- nearest neighbor and Fuzzy K-nearest neighbor. Seventy percent of the features were used for training and thirty percent for testing the algorithm.Results: Analysis of Variance (ANOVA) conveyed that Hurst and the proposed features were statistically significant (hlm < 0.001). Hurst computed using RRS and FVS methods showed similar classification accuracy. The features obtained by combining FVS and HOS performed better with a maximum accuracy of 92.87% and 76.45% for classifying the six emotional states using random and subject independent validation respectively.Conclusions: The results indicate that the combination of non-linear analysis and HOS tend to capture the finer emotional changes that can be seen in healthy ECG data. This work can be further fine tuned to develop a real time system. © 2013 Selvaraj et al.; licensee BioMed Central Ltd.},
nota = {dipetik oleh 42},
kata kunci = {Remaja, Dewasa, Aged, Artikel, Audio-Visual Stimulus, Autonomous Nervous Systems, Anak-anak, Ketepatan Pengelasan, Computer Based Training, Computer-Assisted, Electrocardiogram Signal, Electrocardiography, Emosi, Perempuan, Fuzzy K-nearest Neighbor, Higher-Order Statistic (HOS), Manusia, Kecacatan Intelektual, Sistem Komputer Interaktif, Metodologi, Pertengahan umur, Nonlinear Dynamics, Nonlinear System, Prosedur, Real Time Systems, Pemprosesan isyarat, Statistik, Dewasa Muda},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Modugumudi, Y R; Santhosh, J; Anand, S

Efficacy of collaborative virtual environment intervention programs in emotion expression of children with autism Artikel Jurnal

Journal of Medical Imaging and Health Informatics, 3 (2), hlm. 321-325, 2013, ISSN: 21567018, (dipetik oleh 4).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Autisme, Anak-anak, Artikel Klinikal, Collaborative Virtual Environment, Kajian Terkawal, DSM-IV, Elektroencephalogram, Elektroensefalografi, Electrooculogram, Emosi, Ketua Penolong Pengarah, Event Related Potential, Ekspresi wajah, Perempuan, Manusia, Latent Period, Lelaki, Recognition, Budak sekolah

Assaf, M; Hyatt, C J; Wong, C G; Johnson, ENCIK; Schultz, R T; Hendler, T; Pearlson, G D

Mentalizing and motivation neural function during social interactions in autism spectrum disorders Artikel Jurnal

NeuroImage: klinikal, 3 , hlm. 321-331, 2013, ISSN: 22131582, (dipetik oleh 28).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Autisme, Brain Function, Anak-anak, Komputer, Kajian Terkawal, Perempuan, Pengimejan Resonans Magnetik Berfungsi, Permainan, Groups by Age, Manusia, Kajian Klinikal Utama, Lelaki, Mental Capacity, Middle Temporal Gyrus, Motivasi, Motor Performance, Nerve Cell, Nerve Function, Nucleus Accumbens, Jurnal Keutamaan, Punishment, Ganjaran, Budak sekolah, Kognisi Sosial, Social Environment, Interaksi Sosial, Task Performance, Theory of Mind, Penglihatan

@artikel{Assaf2013321,
tajuk = {Mentalizing and motivation neural function during social interactions in autism spectrum disorders},
pengarang = {M Assaf and C J Hyatt and C G Wong and M R Johnson and R T Schultz and T Hendler and G D Pearlson},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885394367&doi=10.1016%2fj.nicl.2013.09.005&rakan kongsi = 40&md5=b63630c997b658167792266e40e855b6},
doi = {10.1016/j.nicl.2013.09.005},
terbitan = {22131582},
tahun = {2013},
tarikh = {2013-01-01},
jurnal = {NeuroImage: klinikal},
isi padu = {3},
halaman = {321-331},
abstrak = {Gangguan Spektrum Autisme (ASDs) are characterized by core deficits in social functions. Two theories have been suggested to explain these deficits: mind-blindness theory posits impaired mentalizing processes (i.e.. decreased ability for establishing a representation of others' state of mind), while social motivation theory proposes that diminished reward value for social information leads to reduced social attention, social interactions, and social learning. Mentalizing and motivation are integral to typical social interactions, and neuroimaging evidence points to independent brain networks that support these processes in healthy individuals. Walau bagaimanapun, the simultaneous function of these networks has not been explored in individuals with ASDs. We used a social, interactive fMRI task, the Domino game, to explore mentalizing- and motivation-related brain activation during a well-defined interval where participants respond to rewards or punishments (i.e.. motivation) and concurrently process information about their opponent's potential next actions (i.e.. mentalizing). Thirteen individuals with high-functioning ASDs, ages 12-24, dan 14 healthy controls played fMRI Domino games against a computer-opponent and separately, what they were led to believe was a human-opponent. Results showed that while individuals with ASDs understood the game rules and played similarly to controls, they showed diminished neural activity during the human-opponent runs only (i.e.. in a social context) in bilateral middle temporal gyrus (MTG) during mentalizing and right Nucleus Accumbens (NAcc) during reward-related motivation (Pcluster < 0.05 FWE). Importantly, deficits were not observed in these areas when playing against a computer-opponent or in areas related to motor and visual processes. These results demonstrate that while MTG and NAcc, which are critical structures in the mentalizing and motivation networks, masing-masing, activate normally in a non-social context, they fail to respond in an otherwise identical social context in ASD compared to controls. We discuss implications to both the mind-blindness and social motivation theories of ASD and the importance of social context in research and treatment protocols. © 2013 Penulis.},
nota = {dipetik oleh 28},
kata kunci = {Remaja, Dewasa, Artikel, Autisme, Brain Function, Anak-anak, Komputer, Kajian Terkawal, Perempuan, Pengimejan Resonans Magnetik Berfungsi, Permainan, Groups by Age, Manusia, Kajian Klinikal Utama, Lelaki, Mental Capacity, Middle Temporal Gyrus, Motivasi, Motor Performance, Nerve Cell, Nerve Function, Nucleus Accumbens, Jurnal Keutamaan, Punishment, Ganjaran, Budak sekolah, Kognisi Sosial, Social Environment, Interaksi Sosial, Task Performance, Theory of Mind, Penglihatan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Gangguan Spektrum Autisme (ASDs) are characterized by core deficits in social functions. Two theories have been suggested to explain these deficits: mind-blindness theory posits impaired mentalizing processes (i.e.. decreased ability for establishing a representation of others' state of mind), while social motivation theory proposes that diminished reward value for social information leads to reduced social attention, social interactions, and social learning. Mentalizing and motivation are integral to typical social interactions, and neuroimaging evidence points to independent brain networks that support these processes in healthy individuals. Walau bagaimanapun, the simultaneous function of these networks has not been explored in individuals with ASDs. We used a social, interactive fMRI task, the Domino game, to explore mentalizing- and motivation-related brain activation during a well-defined interval where participants respond to rewards or punishments (i.e.. motivation) and concurrently process information about their opponent's potential next actions (i.e.. mentalizing). Thirteen individuals with high-functioning ASDs, ages 12-24, dan 14 healthy controls played fMRI Domino games against a computer-opponent and separately, what they were led to believe was a human-opponent. Results showed that while individuals with ASDs understood the game rules and played similarly to controls, they showed diminished neural activity during the human-opponent runs only (i.e.. in a social context) in bilateral middle temporal gyrus (MTG) during mentalizing and right Nucleus Accumbens (NAcc) during reward-related motivation (Pcluster < 0.05 FWE). Importantly, deficits were not observed in these areas when playing against a computer-opponent or in areas related to motor and visual processes. These results demonstrate that while MTG and NAcc, which are critical structures in the mentalizing and motivation networks, masing-masing, activate normally in a non-social context, they fail to respond in an otherwise identical social context in ASD compared to controls. We discuss implications to both the mind-blindness and social motivation theories of ASD and the importance of social context in research and treatment protocols. © 2013 Penulis.

Tutup

Clark, M; Coklat, R; Karrapaya, R

Pandangan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi kanak-kanak kurang upaya Artikel Jurnal

Jurnal Penyelidikan Kecacatan Intelektual, 56 (1), hlm. 45-60, 2012, ISSN: 09642633, (dipetik oleh 16).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Autisme, Pengasuh, Cerebral Palsy, Anak-anak, Kos Penyakit, Perbandingan Merentas Budaya, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Kanak-kanak Kurang Upaya, Sindrom Down, Keluarga, Kesihatan Keluarga, Perempuan, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Tinjauan Kesihatan, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kepuasan Hidup, Malaysia, Lelaki, Ibu bapa, Dasar, Prasekolah, Kanak-kanak Prasekolah, Psikometrik, Kualiti hidup, Soal selidik, Budak sekolah, Sokongan Sosial, Faktor Sosioekonomi

@artikel{Clark201245,
tajuk = {Pandangan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi kanak-kanak kurang upaya},
pengarang = {M Clark dan R Brown dan R Karrapaya},
url = {https://www.scopus.com/inward/record.uri?eid = 2-s2.0-83855165819&doi=10.1111/j.1365-2788.2011.01408.x&rakan kongsi = 40&md5 = 4822406179501d1b0b93c5374e383637},
doi = {10.1111/j.1365-2788.2011.01408.x},
terbitan = {09642633},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Jurnal Penyelidikan Kecacatan Intelektual},
isi padu = {56},
nombor = {1},
halaman = {45-60},
abstrak = {Latar Belakang Walaupun terdapat banyak literatur dalam kualiti hidup keluarga yang merangkumi anak-anak kurang upaya, majoriti penyelidikan telah dilakukan di negara-negara barat. Kajian ini memberikan penerokaan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi anak-anak yang kurang upaya perkembangan / intelektual. Dinamika yang mencirikan masyarakat Malaysia digambarkan sebagai perkembangan dalam dasar sosial dan penyediaan perkhidmatan yang menyokong orang kurang upaya dan keluarga mereka. Data Kaedah Soal Selidik dikumpulkan menggunakan Tinjauan Kualiti Hidup Keluarga - Versi pendek. Anggota 52 keluarga yang merangkumi satu atau dua kanak-kanak kurang upaya ditemu ramah. Respons mereka memberikan persepsi mereka dalam enam dimensi kualiti hidup keluarga di sembilan domain kehidupan yang dinilai. Hasil Dapatan menunjukkan corak penilaian 'penting' yang dirasakan kuat pada setiap domain kehidupan berbanding dengan penilaian min untuk dimensi kualiti hidup keluarga yang lain. Beberapa dimensi kualiti hidup keluarga, khususnya 'peluang', ínitiative 'dan áttainment', menunjukkan hubungan yang sangat kuat antara satu sama lain. Keseluruhan cara kepuasan dengan dan pencapaian kualiti hidup keluarga serta penilaian global terhadap kualiti hidup dan kepuasan semua menunjukkan hubungan yang signifikan, walaupun setiap korelasi ini menyumbang kurang daripada 50% dari varians biasa. Kesimpulan Peringkat kepentingan dapat dilihat sebagai faktor penentu dari segi kualiti hidup, dan memainkan peranan penting dalam menyokong pencapaian, dan kepuasan dengan, kualiti hidup keluarga, menanggung peluang, inisiatif dan kestabilan mencukupi. Keperluan untuk sampel yang lebih luas termasuk keluarga yang tidak menerima perkhidmatan diperhatikan. Soalan penyelidikan masa depan berdasarkan hasil kajian semasa dan beberapa dinamika yang mempengaruhi masyarakat Malaysia juga dicadangkan. © 2011 Penulis. Jurnal Penyelidikan Kecacatan Intelektual © 2011 Blackwell Publishing Ltd.},
nota = {dipetik oleh 16},
kata kunci = {Remaja, Dewasa, Artikel, Autisme, Pengasuh, Cerebral Palsy, Anak-anak, Kos Penyakit, Perbandingan Merentas Budaya, Ketidakupayaan Perkembangan, Gangguan Perkembangan, Kanak-kanak Kurang Upaya, Sindrom Down, Keluarga, Kesihatan Keluarga, Perempuan, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Tinjauan Kesihatan, Manusia, Kecacatan Intelektual, Kemerosotan Intelektual, Kepuasan Hidup, Malaysia, Lelaki, Ibu bapa, Dasar, Prasekolah, Kanak-kanak Prasekolah, Psikometrik, Kualiti hidup, Soal selidik, Budak sekolah, Sokongan Sosial, Faktor Sosioekonomi},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Latar Belakang Walaupun terdapat banyak literatur dalam kualiti hidup keluarga yang merangkumi anak-anak kurang upaya, majoriti penyelidikan telah dilakukan di negara-negara barat. Kajian ini memberikan penerokaan awal mengenai kualiti hidup keluarga Malaysia yang merangkumi anak-anak yang kurang upaya perkembangan / intelektual. Dinamika yang mencirikan masyarakat Malaysia digambarkan sebagai perkembangan dalam dasar sosial dan penyediaan perkhidmatan yang menyokong orang kurang upaya dan keluarga mereka. Data Kaedah Soal Selidik dikumpulkan menggunakan Tinjauan Kualiti Hidup Keluarga - Versi pendek. Anggota 52 keluarga yang merangkumi satu atau dua kanak-kanak kurang upaya ditemu ramah. Respons mereka memberikan persepsi mereka dalam enam dimensi kualiti hidup keluarga di sembilan domain kehidupan yang dinilai. Hasil Dapatan menunjukkan corak penilaian 'penting' yang dirasakan kuat pada setiap domain kehidupan berbanding dengan penilaian min untuk dimensi kualiti hidup keluarga yang lain. Beberapa dimensi kualiti hidup keluarga, khususnya 'peluang', ínitiative 'dan áttainment', menunjukkan hubungan yang sangat kuat antara satu sama lain. Keseluruhan cara kepuasan dengan dan pencapaian kualiti hidup keluarga serta penilaian global terhadap kualiti hidup dan kepuasan semua menunjukkan hubungan yang signifikan, walaupun setiap korelasi ini menyumbang kurang daripada 50% dari varians biasa. Kesimpulan Peringkat kepentingan dapat dilihat sebagai faktor penentu dari segi kualiti hidup, dan memainkan peranan penting dalam menyokong pencapaian, dan kepuasan dengan, kualiti hidup keluarga, menanggung peluang, inisiatif dan kestabilan mencukupi. Keperluan untuk sampel yang lebih luas termasuk keluarga yang tidak menerima perkhidmatan diperhatikan. Soalan penyelidikan masa depan berdasarkan hasil kajian semasa dan beberapa dinamika yang mempengaruhi masyarakat Malaysia juga dicadangkan. © 2011 Penulis. Jurnal Penyelidikan Kecacatan Intelektual © 2011 Blackwell Publishing Ltd.

Tutup

Salih, M R M; Laut, M B; Hassali, M A A; Shafie, A A; Al-Lela, Wahai Q B; Abd, Ke dan; Ganesan, V M

Characteristics of seizure frequency among Malaysian children diagnosed with structural-metabolic epilepsy Artikel Jurnal

Journal of Neurosciences in Rural Practice, 3 (3), hlm. 244-250, 2012, ISSN: 09763147, (dipetik oleh 1).

Abstrak | Pautan | BibTeX | Tag: Remaja, Anticonvulsive Agent, Artikel, Autisme, Benign Childhood Epilepsy, Brain Disease, Carbamazepine, Cerebral Palsy, Anak-anak, Chinese, Clonazepam, Analisis Kohort, Congenital Toxoplasmosis, Kajian Terkawal, Corpus Callosum Agenesis, Dandy Walker Syndrome, Degenerative Disease, Gangguan Perkembangan, Disorders of Mitochondrial Functions, Sindrom Down, Epilepsi, Etnik, Etiracetam, Perempuan, Focal Epilepsy, Happy Puppet Syndrome, Manusia, Hydrocephalus, Orang India, Kemerosotan Intelektual, Lamotrigine, Kajian Klinikal Utama, Malay, Lelaki, Medical Record, Microcephaly, Monotherapy, Kanak-kanak Prasekolah, Jurnal Keutamaan, Kajian Retrospektif, Budak sekolah, Seizure, Structural Metabolic Epilepsy, Tuberous Sclerosis, Valproic Acid, Wilson Disease

@artikel{Salih2012244,
tajuk = {Characteristics of seizure frequency among Malaysian children diagnosed with structural-metabolic epilepsy},
pengarang = {M R M Salih and M B Bahari and M A A Hassali and A A Shafie and O Q B Al-Lela and A Y Abd and V M Ganesan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870233746&doi=10.4103%2f0976-3147.102596&rakan kongsi = 40&md5=039bd22d6c38366ebfdd00a4254c20f0},
doi = {10.4103/0976-3147.102596},
terbitan = {09763147},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Journal of Neurosciences in Rural Practice},
isi padu = {3},
nombor = {3},
halaman = {244-250},
abstrak = {Pengenalan: Seizure-free patients or substantial reduction in seizure frequency are the most important outcome measures in the management of epilepsy. The study aimed to evaluate the patterns of seizure frequency and its relationship with demographics, clinical characteristics, and outcomes. Materials and Methods: A retrospective cohort study was conducted at the Pediatric Neurology Clinic, Hospital Pulau Pinang. Over a period of 6 bulan, the required data were extracted from the medical records using a pre-designed data collection form. Keputusan: Seizure frequency showed no significant association with patient's demographics and clinical characteristic. Walau bagaimanapun, significant reduction in seizure frequency from the baseline to the last follow-up visit was only seen in certain subgroups of patients including Malays, perempuan, patients <4 years of age, patients with global developmental delay/intellectual disability, and patients with focal seizure. There was no significant association between seizure frequency and rate of adverse events. Polytherapy visits were associated with higher seizure frequency than monotherapy visits (27.97 ± 56.66, 10.94 ± 30.96 attack per month, respectively) (P < 0.001). There was a clear tendency to get antiepileptic drugs used at doses above the recommended range in polytherapy (8.4%) rather than in monotherapy (1.4%) visits (P < 0.001). A significant correlation was found between seizure frequency and number of visits per patient per year (r = 0.450, P < 0.001). Conclusion: Among children with structural-metabolic epilepsy, Malays, females, patients <4 years of age, patients with global developmental delay/intellectual disability and patients manifested with focal seizure are more responsive antiepileptic drug therapy than the other subgroups of patients.},
nota = {dipetik oleh 1},
kata kunci = {Remaja, Anticonvulsive Agent, Artikel, Autisme, Benign Childhood Epilepsy, Brain Disease, Carbamazepine, Cerebral Palsy, Anak-anak, Chinese, Clonazepam, Analisis Kohort, Congenital Toxoplasmosis, Kajian Terkawal, Corpus Callosum Agenesis, Dandy Walker Syndrome, Degenerative Disease, Gangguan Perkembangan, Disorders of Mitochondrial Functions, Sindrom Down, Epilepsi, Etnik, Etiracetam, Perempuan, Focal Epilepsy, Happy Puppet Syndrome, Manusia, Hydrocephalus, Orang India, Kemerosotan Intelektual, Lamotrigine, Kajian Klinikal Utama, Malay, Lelaki, Medical Record, Microcephaly, Monotherapy, Kanak-kanak Prasekolah, Jurnal Keutamaan, Kajian Retrospektif, Budak sekolah, Seizure, Structural Metabolic Epilepsy, Tuberous Sclerosis, Valproic Acid, Wilson Disease},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Tan, E H; Razak, S A; Abdullah, J M; Yusoff, Mohamed A A

De-novo mutations and genetic variation in the SCN1A gene in Malaysian patients with generalized epilepsy with febrile seizures plus (GEFS+) Artikel Jurnal

Epilepsy Research, 102 (3), hlm. 210-215, 2012, ISSN: 09201211, (dipetik oleh 2).

Abstrak | Pautan | BibTeX | Tag: Alanine, Amino Acid Substitution, Arginine, Artikel, Asparagine, Aspartic Acid, Anak-anak, Artikel Klinikal, Clinical Feature, Kajian Terkawal, Persatuan Penyakit, DNA Mutational Analysis, DNA Sequence, Elektroensefalografi, Epilepsi, Febrile, Febrile Convulsion, Perempuan, Gen, Gene Frequency, Pengenalan Gen, Generalized, Generalized Epilepsy, Persatuan Genetik, Kecenderungan Genetik, Genetic Screening, Genetic Variability, Glycine, Histidine, Manusia, Bayi, Malaysia, Lelaki, Missense Mutation, Molecular Pathology, Mutation, Mutational Analysis, Mutator Gene, Nav1.1 Voltage-Gated Sodium Channel, Onset Age, Patient Assessment, Polimorfisme, Kanak-kanak Prasekolah, Jurnal Keutamaan, Promoter Region, Budak sekolah, Seizure, Sequence Analysis, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal, Sodium Channel Nav1.1, Voltage Gated Sodium Channel Alpha1 Subunit Gene

@artikel{Tan2012210,
tajuk = {De-novo mutations and genetic variation in the SCN1A gene in Malaysian patients with generalized epilepsy with febrile seizures plus (GEFS+)},
pengarang = {E H Tan and S A Razak and J M Abdullah and A A Mohamed Yusoff},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870296042&doi=10.1016%2fj.eplepsyres.2012.08.004&rakan kongsi = 40&md5=25cc4eeb07db2492a7c04c6b3b3b2167},
doi = {10.1016/j.eplepsyres.2012.08.004},
terbitan = {09201211},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Epilepsy Research},
isi padu = {102},
nombor = {3},
halaman = {210-215},
abstrak = {Generalized epilepsy with febrile seizures plus (GEFS+) comprises a group of clinically and genetically heterogeneous epilepsy syndrome. Di sini, we provide the first report of clinical presentation and mutational analysis of SCN1A gene in 36 Malaysian GEFS+ patients. Mutational analysis of SCN1A gene revealed twenty seven sequence variants (missense mutation and silent polymorphism also intronic polymorphism), as well as 2 novel de-novo mutations were found in our patients at coding regions, c.5197A>G (N1733D) and c.4748A>G (H1583R). Our findings provide potential genetic insights into the pathogenesis of GEFS+ in Malaysian populations concerning the SCN1A gene mutations. © 2012 Elsevier B.V.},
nota = {dipetik oleh 2},
kata kunci = {Alanine, Amino Acid Substitution, Arginine, Artikel, Asparagine, Aspartic Acid, Anak-anak, Artikel Klinikal, Clinical Feature, Kajian Terkawal, Persatuan Penyakit, DNA Mutational Analysis, DNA Sequence, Elektroensefalografi, Epilepsi, Febrile, Febrile Convulsion, Perempuan, Gen, Gene Frequency, Pengenalan Gen, Generalized, Generalized Epilepsy, Persatuan Genetik, Kecenderungan Genetik, Genetic Screening, Genetic Variability, Glycine, Histidine, Manusia, Bayi, Malaysia, Lelaki, Missense Mutation, Molecular Pathology, Mutation, Mutational Analysis, Mutator Gene, Nav1.1 Voltage-Gated Sodium Channel, Onset Age, Patient Assessment, Polimorfisme, Kanak-kanak Prasekolah, Jurnal Keutamaan, Promoter Region, Budak sekolah, Seizure, Sequence Analysis, Nukleotida Tunggal, Polimorfisme Nukleotida Tunggal, Sodium Channel Nav1.1, Voltage Gated Sodium Channel Alpha1 Subunit Gene},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Tan, E H; Yusoff, A A M; Abdullah, J M; Razak, S A

Generalized epilepsy with febrile seizure plus (GEFS+) spectrum: Novel de novo mutation of SCN1A detected in a Malaysian patient Artikel Jurnal

Journal of Pediatric Neurosciences, 7 (2), hlm. 123-125, 2012, ISSN: 18171745, (dipetik oleh 3).

Abstrak | Pautan | BibTeX | Tag: Remaja, Anxiety Disorder, Artikel, Autisme, Carbamazepine, Laporan kes, Computer Assisted Tomography, Elektroencephalogram, Elektroensefalografi, Febrile Convulsion, Gen, Generalized Epilepsy, Generalized Epilepsy with Febrile Seizure Plus, Manusia, Karyotype, Malaysia, Lelaki, Medical History, Mental Deficiency, Missense Mutation, Nuclear Magnetic Resonance Imaging, Fenotip, SCN1A Gene, Tonic Clonic Seizure, Topiramate, Valproic Acid

@artikel{Tan2012123,
tajuk = {Generalized epilepsy with febrile seizure plus (GEFS+) spectrum: Novel de novo mutation of SCN1A detected in a Malaysian patient},
pengarang = {E H Tan and A A M Yusoff and J M Abdullah and S A Razak},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870194979&doi=10.4103%2f1817-1745.102575&rakan kongsi = 40&md5=b73f0bdb583e84404e0fff232faf30cb},
doi = {10.4103/1817-1745.102575},
terbitan = {18171745},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Journal of Pediatric Neurosciences},
isi padu = {7},
nombor = {2},
halaman = {123-125},
abstrak = {Dalam laporan ini, we describe a 15-year-old Malaysian male patient with a de novo SCN1A mutation who experienced prolonged febrile seizures after his first seizure at 6 months of age. This boy had generalized tonic clonic seizure (GTCS) which occurred with and without fever. Sequencing analysis of voltage-gated sodium channel a1-subunit gene, SCN1A, confirmed a homozygous A to G change at nucleotide 5197 (c.5197A > G) in exon 26 resulting in amino acid substitution of asparagines to aspartate at codon 1733 of sodium channel. The mutation identified in this patient is located in the pore-forming loop of SCN1A and this case report suggests missense mutation in pore-forming loop causes generalized epilepsy with febrile seizure plus (GEFS+) with clinically more severe neurologic phenotype including intellectual disabilities (mental retardation and autism features) and neuropsychiatric disease (anxiety disorder).},
nota = {dipetik oleh 3},
kata kunci = {Remaja, Anxiety Disorder, Artikel, Autisme, Carbamazepine, Laporan kes, Computer Assisted Tomography, Elektroencephalogram, Elektroensefalografi, Febrile Convulsion, Gen, Generalized Epilepsy, Generalized Epilepsy with Febrile Seizure Plus, Manusia, Karyotype, Malaysia, Lelaki, Medical History, Mental Deficiency, Missense Mutation, Nuclear Magnetic Resonance Imaging, Fenotip, SCN1A Gene, Tonic Clonic Seizure, Topiramate, Valproic Acid},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Cheah, P -S; Ramshaw, H S; Thomas, P; Toyo-Oka, K; Syiling, X; Martin, S; Coyle, P; Guthridge, M A; Stomski, F; Tetapi, Van Den M; Wynshaw-Boris, A; Lopez, A F; Schwarz, Q

Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency Artikel Jurnal

Molecular Psychiatry, 17 (4), hlm. 451-466, 2012, ISSN: 13594184, (dipetik oleh 58).

Abstrak | Pautan | BibTeX | Tag: 14-3-3 Proteins, Animal Experiment, Animal Model, Animal Tissue, Haiwan, Artikel, Autisme, Gangguan Tingkah Laku, Bipolar Disorder, Otak, Cell Movement, Sel, Cognitive Defect, Kajian Terkawal, Berbudaya, Disease Models, Disrupted in Schizophrenia 1 Protein, Embryo, Perempuan, Gen, Gene Deletion, Kecenderungan Genetik kepada Penyakit, Glutamic Acid, Hippocampal Mossy Fiber, Hippocampus, Manusia, Hiperaktif, Inbred C57BL, Isoprotein, Knockout, Belajar, Lelaki, Maze Learning, Memory, Tikus, Motor Activity, Tetikus, Neurogenesis, Neuronal Migration Disorder, Neurons, Neuropsychiatry, Bukan Manusia, Jurnal Keutamaan, Protein 14-3-3, Protein 14-3-3 Zeta, Protein Deficiency, Protein Interaction, Recognition, Faktor risiko, Skizofrenia, Sensory Gating, Synapse, Dadah yang tidak dikelaskan

@artikel{Cheah2012451,
tajuk = {Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency},
pengarang = {P -S Cheah and H S Ramshaw and P Q Thomas and K Toyo-Oka and X Xu and S Martin and P Coyle and M A Guthridge and F Stomski and M Van Den Buuse and A Wynshaw-Boris and A F Lopez and Q P Schwarz},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859007028&doi=10.1038%2fmp.2011.158&rakan kongsi = 40&md5=7f507fef31a192a10b3cde7bf69b5442},
doi = {10.1038/mp.2011.158},
terbitan = {13594184},
tahun = {2012},
tarikh = {2012-01-01},
jurnal = {Molecular Psychiatry},
isi padu = {17},
nombor = {4},
halaman = {451-466},
abstrak = {Complex neuropsychiatric disorders are believed to arise from multiple synergistic deficiencies within connected biological networks controlling neuronal migration, axonal pathfinding and synapse formation. Di sini, we show that deletion of 14-3-3ζ causes neurodevelopmental anomalies similar to those seen in neuropsychiatric disorders such as schizophrenia, autism spectrum disorder and bipolar disorder. 14-3-3ζ-Deficient mice displayed striking behavioural and cognitive deficiencies including a reduced capacity to learn and remember, hyperactivity and disrupted sensorimotor gating. These deficits are accompanied by subtle developmental abnormalities of the hippocampus that are underpinned by aberrant neuronal migration. Significantly, 14-3-3ζ- deficient mice exhibited abnormal mossy fibre navigation and glutamatergic synapse formation. The molecular basis of these defects involves the schizophrenia risk factor, DISC1, which interacts isoform specifically with 14-3-3ζ. Our data provide the first evidence of a direct role for 14-3-3ζ deficiency in the aetiology of neurodevelopmental disorders and identifies 14-3-3ζ as a central risk factor in the schizophrenia protein interaction network. © 2012 Macmillan Publishers Limited All rights reserved.},
nota = {dipetik oleh 58},
kata kunci = {14-3-3 Proteins, Animal Experiment, Animal Model, Animal Tissue, Haiwan, Artikel, Autisme, Gangguan Tingkah Laku, Bipolar Disorder, Otak, Cell Movement, Sel, Cognitive Defect, Kajian Terkawal, Berbudaya, Disease Models, Disrupted in Schizophrenia 1 Protein, Embryo, Perempuan, Gen, Gene Deletion, Kecenderungan Genetik kepada Penyakit, Glutamic Acid, Hippocampal Mossy Fiber, Hippocampus, Manusia, Hiperaktif, Inbred C57BL, Isoprotein, Knockout, Belajar, Lelaki, Maze Learning, Memory, Tikus, Motor Activity, Tetikus, Neurogenesis, Neuronal Migration Disorder, Neurons, Neuropsychiatry, Bukan Manusia, Jurnal Keutamaan, Protein 14-3-3, Protein 14-3-3 Zeta, Protein Deficiency, Protein Interaction, Recognition, Faktor risiko, Skizofrenia, Sensory Gating, Synapse, Dadah yang tidak dikelaskan},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Freeth, M; Panggil, D; Mitchell, P; Kapten, P; Loher, S

Brief report: How adolescents with ASD process social information in complex scenes. Combining evidence from eye movements and verbal descriptions Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 41 (3), hlm. 364-371, 2011, ISSN: 01623257, (dipetik oleh 21).

Abstrak | Pautan | BibTeX | Tag: Remaja, Artikel, Association, Perhatian, Autisme, Gangguan Perkembangan Kanak-kanak, Anak-anak, Artikel Klinikal, Kajian Terkawal, Cues, Emosi, Eye Fixation, Pergerakan Mata, Eye Tracking, Perempuan, Gaze, Manusia, Intelligence Quotient, Lelaki, Mental Function, Kesihatan mental, Persepsi, Meresap, Photic Stimulation, Photostimulation, Jurnal Keutamaan, Aspek Psikologi, Budak sekolah, Aspek Sosial, Social Perception, Stimulus Response, Komunikasi Lisan, Penglihatan, Persepsi Visual, Visual Stimulation

@artikel{Freeth2011364,
tajuk = {Brief report: How adolescents with ASD process social information in complex scenes. Combining evidence from eye movements and verbal descriptions},
pengarang = {M Freeth and D Ropar and P Mitchell and P Chapman and S Loher},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-79956006659&doi=10.1007%2fs10803-010-1053-4&rakan kongsi = 40&md5=35b5c8dd813f7eab2963b27081f11e78},
doi = {10.1007/s10803-010-1053-4},
terbitan = {01623257},
tahun = {2011},
tarikh = {2011-01-01},
jurnal = {Jurnal Autisme dan Gangguan Perkembangan},
isi padu = {41},
nombor = {3},
halaman = {364-371},
abstrak = {We investigated attention, encoding and processing of social aspects of complex photographic scenes. Twenty-four high-functioning adolescents (berumur 11-16) with ASD and 24 typically developing matched control participants viewed and then described a series of scenes, each containing a person. Analyses of eye movements and verbal descriptions provided converging evidence that both groups displayed general interest in the person in each scene but the salience of the person was reduced for the ASD participants. Namun begitu, the verbal descriptions revealed that participants with ASD frequently processed the observed person's emotion or mental state without prompting. They also often mentioned eye-gaze direction, and there was evidence from eye movements and verbal descriptions that gaze was followed accurately. The combination of evidence from eye movements and verbal descriptions provides a rich insight into the way stimuli are processed overall. The merits of using these methods within the same paradigm are discussed. © Springer Science+Business Media, LLC 2010.},
nota = {dipetik oleh 21},
kata kunci = {Remaja, Artikel, Association, Perhatian, Autisme, Gangguan Perkembangan Kanak-kanak, Anak-anak, Artikel Klinikal, Kajian Terkawal, Cues, Emosi, Eye Fixation, Pergerakan Mata, Eye Tracking, Perempuan, Gaze, Manusia, Intelligence Quotient, Lelaki, Mental Function, Kesihatan mental, Persepsi, Meresap, Photic Stimulation, Photostimulation, Jurnal Keutamaan, Aspek Psikologi, Budak sekolah, Aspek Sosial, Social Perception, Stimulus Response, Komunikasi Lisan, Penglihatan, Persepsi Visual, Visual Stimulation},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Sheppard, E; Panggil, D; Di bawah kayu, G; Loon, Dari E

Brief report: Driving hazard perception in autism Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 40 (4), hlm. 504-508, 2010, ISSN: 01623257, (dipetik oleh 42).

Abstrak | Pautan | BibTeX | Tag: Remaja, Dewasa, Artikel, Association, Autisme, Gangguan Spektrum Autisme, Automobile Driving, Car Driving, Case-Control Studies, Artikel Klinikal, Kajian Terkawal, Hazard Assessment, Manusia, Information Processing, Intelligence Quotient, Lelaki, Kesihatan mental, Motor Dysfunction, Neuropsychological Tests, Persepsi, Photic Stimulation, Jurnal Keutamaan, Reaction Time, Social Perception, Traffic Accident, Traffic Safety, Visual Impairment, Persepsi Visual, Visual Stimulation, Dewasa Muda

Amar, H S S

Meeting the needs of children with disability in Malaysia Artikel Jurnal

Medical Journal of Malaysia, 63 (1), hlm. 1-3, 2008, ISSN: 03005283, (dipetik oleh 20).

Pautan | BibTeX | Tag: Autisme, Behaviour Modification, Pembangunan kanak-kanak, Child Health Care, Anak-anak, Clinical Assessment, Membuat Keputusan Klinikal, Gangguan Perkembangan, Developmental Screening, Kanak-kanak Kurang Upaya, Editorial, Penjagaan Kesihatan, Penyampaian Penjagaan Kesihatan, Health Practitioner, Health Program, Tinjauan Kesihatan, Manusia, Kemerosotan Intelektual, Gangguan Pembelajaran, Malaysia, Pediatric Physiotherapy, Pediatric Rehabilitation, Physical Disability, Prasekolah, Public Health Service, Register, Kepekaan dan Kekhususan, Sensory Dysfunction, Penyesuaian Sosial, Social Welfare, Terapi ucapan, Support Group, United Kingdom, United States

Blum, J D; Talib, N

Balancing individual rights versus collective good in public health enforcement Artikel Jurnal

Medicine and Law, 25 (2), hlm. 273-281, 2006, ISSN: 07231393, (dipetik oleh 6).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Zaman kanak-kanak, Court, Freedom, Government, Harm Reduction, Manusia, Human Rights, Immunization, Infection Control, Infection Prevention, Jurisprudence, Mercury, Parental Behavior, Public Health Service, Severe Acute Respiratory Syndrome, Severe Acute Respiratory Syndrome Vaccine, Social Isolation, Treatment Refusal, United States, Vaccination

@artikel{Blum2006273,
tajuk = {Balancing individual rights versus collective good in public health enforcement},
pengarang = {J D Blum and N Talib},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746936600&rakan kongsi = 40&md5=a2c4c6236febc643356d94b27241a893},
terbitan = {07231393},
tahun = {2006},
tarikh = {2006-01-01},
jurnal = {Medicine and Law},
isi padu = {25},
nombor = {2},
halaman = {273-281},
penerbit = {Yozmot Heiliger Ltd},
abstrak = {This paper explores the balance between common good and individual liberty in the context of public health regulation. The issues are explored in reference to two areas of regulation, isolation and quarantine in the case of SARS, and the rights of parents to refuse mandatory childhood immunizations. In the case of SARS, the analysis explores the age old practice of isolation and quarantine, an important preventive measure with clear civil liberty implications. In reference to childhood immunization the paper considers the American controversy involving the refusal of parents to have their children vaccinated, fearing that mercury in vaccines will lead to autism. The analysis explores the US Supreme Court case of Jacobson v. Massachusetts which 100 years ago established a four part test for evaluating claims of individuals that government public health authorities were infringing on their liberty interests. The paper endorses the four elements of necessity, reasonableness, proportionality, and harm avoidance identified in Jacobson, but calls for a more rigorous scientific evaluation to accompany this traditional test. © YOZMOT 2006.},
nota = {dipetik oleh 6},
kata kunci = {Artikel, Autisme, Zaman kanak-kanak, Court, Freedom, Government, Harm Reduction, Manusia, Human Rights, Immunization, Infection Control, Infection Prevention, Jurisprudence, Mercury, Parental Behavior, Public Health Service, Severe Acute Respiratory Syndrome, Severe Acute Respiratory Syndrome Vaccine, Social Isolation, Treatment Refusal, United States, Vaccination},
pubstate = {diterbitkan},
tppubtype = {artikel}
}

Tutup

Jayachandra, S

Is secretin effective in treatment for Autism Spectrum Disorders (ASD)? Artikel Jurnal

International Journal of Psychiatry in Medicine, 35 (1), hlm. 99-101, 2005, ISSN: 00912174, (dipetik oleh 2).

Pautan | BibTeX | Tag: Autisme, Gangguan Spektrum Autisme, Anak-anak, Clinical Trial, Drug Effect, Drug Efficacy, Drug Mechanism, Gastrointestinal Symptom, Manusia, Hypersensitivity, Injections, Intravenous, Surat, Secretin, Hasil Rawatan

Jayachandra, S

Need for internet based scoring system for autism treatment evaluation [2] Artikel Jurnal

Jurnal Autisme dan Gangguan Perkembangan, 35 (5), hlm. 685, 2005, ISSN: 01623257, (dipetik oleh 1).

Pautan | BibTeX | Tag: Sindrom Asperger, Autisme, Gangguan Spektrum Autisme, Diagnostic and Statistical Manual of Mental Disorders, Evaluation, Perkhidmatan kesihatan, Health Services Needs and Demand, Manusia, Bayi, Infantile Autism, Instrumentation, Internet, Surat, Jurnal Keutamaan, Psychoeducation, Psychotherapy, Reliability, Sistem Pemarkahan, Hasil Rawatan

Kasmini, K; Zasmani, S

Sindrom Asperger: laporan dua kes dari Malaysia. Artikel Jurnal

Jurnal perubatan Singapura, 36 (6), hlm. 641-643, 1995, ISSN: 00375675, (dipetik oleh 2).

Abstrak | Pautan | BibTeX | Tag: Artikel, Autisme, Gangguan Spektrum Autisme, Laporan kes, Gangguan Perkembangan Kanak-kanak, Anak-anak, Pengelasan (maklumat), Manusia, Gangguan Perkembangan Bahasa, Ketidakupayaan Bahasa, Malaysia, Lelaki, Meresap, Skala Penarafan Status Psikiatri, Aspek Psikologi, Skala Penarafan Psikologi, Kelakuan Sosial, Kelakuan Stereotaip, Stereotaip, Sindrom