@article{ISI:000488883000001,
title = {LEVELS OF PERMEABILITY AND WAYFINDING IN AUTISM INSTITUTION},
author = {Lim Heng Yi and Ahmad Sanusi Hassan and Yasser Arab and Rasha Saeed Abdulla Ba Angood},
doi = {10.14456/ITJEMAST.2019.179},
issn = {2228-9860},
year = {2019},
date = {2019-01-01},
journal = {INTERNATIONAL TRANSACTION JOURNAL OF ENGINEERING MANAGEMENT & APPLIED
SCIENCES & TECHNOLOGIES},
volume = {10},
number = {14, SI},
publisher = {TUENGR GROUP},
address = {88-244 MOO 3 KLONG NO 2 KLONG-LUANG, PATHUMTAN, 12120, THAILAND},
abstract = {Autism Institute is an organisation that helps autistic students who
need legal and special education with appropriate programs and services.
This study is to identify the level of permeability and wayfinding which
determines the quality of the building's spatial configuration. This
research evaluates the space planning through the floor layout plans
which will discover and understand the quality of spatial configuration
for Autism Institute. To achieve the research objective, the research
study investigates educational and autism institutions with reference to
space syntax analysis. The case studies selected for analysis were
Flower with Kindergarten in South Korea and Pacific Autism Family Center
in Canada. A justified graph and numbering indication system for each
case study are conducted, and the resulting graph is compared and
summarised based on the level of permeability, wayfinding and spatial
configuration in relation to space syntax. (C) 2019 INT TRANS J ENG
MANAG SCI TECH.},
keywords = {Justified Graph, Permeability, Space Syntax, Spatial Configuration, Wayfinding Analysis},
pubstate = {published},
tppubtype = {article}
}

@article{EiThu2018865,
title = {New insight in improving therapeutic efficacy of antipsychotic agents: An overview of improved in vitro and in vivo performance, efficacy upgradation and future prospects},
author = {H Ei Thu and Z Hussain and A N Shuid},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048981535&doi=10.2174%2f1389450117666161125174625&partnerID=40&md5=d32e5bc9766ff9d68dd79f082b9ca4bc},
doi = {10.2174/1389450117666161125174625},
issn = {13894501},
year = {2018},
date = {2018-01-01},
journal = {Current Drug Targets},
volume = {19},
number = {8},
pages = {865-876},
publisher = {Bentham Science Publishers B.V.},
abstract = {Psychotic disorders are recognized as severe mental disorders that rigorously affect pa-tient’s personality, critical thinking, and perceptional ability. High prevalence, global dissemination and limitations of conventional pharmacological approaches compel a significant burden to the patient, medical professionals and the healthcare system. To date, numerous orally administered therapies are available for the management of depressive disorders, schizophrenia, anxiety, bipolar disorders and autism spectrum problems. However, poor water solubility, erratic oral absorption, extensive first-pass metabolism, low oral bioavailability and short half-lives are the major factors which limit the pharmaceutical significance and therapeutic feasibility of these agents. In recent decades, nanotechnology-based delivery systems have gained remarkable attention of the researchers to mitigate the pharmaceutical issues related to the antipsychotic therapies and to optimize their oral drug delivery, therapeutic outcomes, and patient compliance. Therefore, the present review was aimed to summarize the available in vitro and in vivo evidences signifying the pharmaceutical importance of the advanced delivery systems in improving the aqueous solubility, transmembrane permeability, oral bioavailability and therapeutic outcome of the antipsychotic agents. © 2018 Bentham Science Publishers.},
note = {cited By 2},
keywords = {Amisulpride, Amitriptyline, Animals, Antipsychotic Agents, Anxiety, Aripiprazole, Autism, Bioavailability, Biological Availability, Bipolar Disorder, Buspirone, Chemistry, Clonazepam, Clozapine, Depression, Diazepam, Drug Delivery System, Drug Delivery Systems, Duloxetine, Half Life Time, Half-Life, Health Care, Human, Iloperidone, In Vitro Study, In Vivo Study, Mental Disease, Mental Disorders, Midazolam, Nanotechnology, Neuroleptic Agent, Olanzapine, Pathophysiology, Permeability, Physical Chemistry, Psychosis, Review, Risperidone, Schizophrenia, Solubility, Sulpiride, Treatment Outcome, Venlafaxine, Ziprasidone},
pubstate = {published},
tppubtype = {article}
}