List of Publications
There are numbers of autism related research can be found in Malaysia that generally focus on the ASD, learning disorder, communication aids, therapy and many more. The list of publications is provided below:
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2019 |
Ismail, W; Zamin, N; Hanafi, M H; Mohamad, A H Institute of Electrical and Electronics Engineers Inc., 2019, ISBN: 9781728108513, (cited By 0). Abstract | Links | BibTeX | Tags: Architecture, Clouds, Computer-Based System, Diseases, Distributed Computer Systems, Health Care System, Hospitals, Non-Communicable Disease, Patient Rehabilitation, Rehabilitation Services, Scientific Studies, Stroke Patients, Telerehabilitation, Traditional Systems, Virtual Reality @conference fusion-row 3, author = fusion-row 2, url = fusion-row 1, doi = fusion-row 0, isbn = #main 9, year = #main 8, date = #main 7, journal = #main 6, pages = #main 5, publisher = #main 4, abstract = #main 3, note = #main 2, keywords = #main 1, pubstate = #main 0, tppubtype = xt-visitor-counter 9 } Rehabilitation in healthcare systems provides therapy and training to restore quality life after certain illness, addiction or accident. Currently, there is a significant unmet need for rehabilitation services, and it is frequently undervalued in the health system. As populations age and the prevalence of noncommunicable diseases and injuries increases, and the demand for rehabilitation grows, strengthening rehabilitation in health systems becomes ever more paramount. Conventional rehabilitation service can be costly and time consuming to people not living near the rehabilitation centres. Often people with lower income who live in rural areas refuse rehabilitation services due to the logistic issue. On the other hand, in urban areas, most people are too busy with their daily activities and unable to keep their therapy schedule consistently. In consequence, patients do not enjoy the actual benefit of rehabilitation because of a certain limitation such as cost and time. These limitations can be surpassed by putting telerehabilitation, an emerging area of performing rehabilitation medical treatment with the use of technology from a distance into practice. Scientific studies of telerehabilitation in the current literature are discussing primarily in the area of readiness, technologies, and illnesses such as children autism and heart failure. However, there is limited evidence about telerehabilitation service for stroke patients, concentrating on the pre-implementation and implementation stages, which makes this paper viable and significant, potentially for telerehabilitation implementation in Malaysia. This paper proposes a new conceptual model of hybrid telerehabilitation that combines several technological principles, such as cloud, virtual reality, and computer-based system. The model was derived based on a study of a public tertiary hospital in Malaysia. The current traditional system was investigated and discussed. A new telerehabilitation model is proposed to widen the access for rehabilitation to patients of all ages. © 2019 IEEE. |
Adib, N A N; Ibrahim, M I; Rahman, A A; Bakar, R S; Yahaya, N A; Hussin, S; Mansor, Wan W N A Predictors of caregivers’ satisfaction with the management of children with autism spectrum disorder: A study at multiple levels of health care Journal Article International Journal of Environmental Research and Public Health, 16 (10), 2019, ISSN: 16617827, (cited By 0). Abstract | Links | BibTeX | Tags: Adult, Article, Autism, Autism Spectrum Disorders, Caregiver, Child Care, Children, Comorbidity, Consultation, Controlled Study, Cross-Sectional Study, Female, Health Care, Health Care Delivery, Health Care System, Health Service, Health Worker, Human, Job Satisfaction, Kelantan, Major Clinical Study, Malaysia, Male, Management, Mental Health, Middle Aged, Occupational Therapy, Parent Satisfaction Scale Questionnaire, Perception, Personal Satisfaction, Primary Health Care, Primary Medical Care, Psychology, Questionnaires, Satisfaction, Secondary Health Care, Speech Therapy, Surveys, Tertiary Health Care, West Malaysia @article xt-visitor-counter 8, author = xt-visitor-counter 7, url = xt-visitor-counter 6, doi = xt-visitor-counter 5, issn = xt-visitor-counter 4, year = xt-visitor-counter 3, date = xt-visitor-counter 2, journal = xt-visitor-counter 1, volume = xt-visitor-counter 0, number = [if lt IE 9]> publisher = [if lt IE 9]> abstract = [if lt IE 9]> note = [if lt IE 9]> keywords = [if lt IE 9]> pubstate = [if lt IE 9]> tppubtype = [if lt IE 9]> } Background: Caregivers are the initial gatekeepers in the health care management of children with autism spectrum disorder (ASD). Methods: This cross-sectional study aimed to determine the factors associated with caregivers’ satisfaction with different levels of health care services in managing children with ASD in Kelantan. The satisfaction scores of 227 main caregivers of confirmed ASD children were assessed with a modified Parent Satisfaction Scale (PSS) questionnaire. Results: The analysis showed that caregivers who waited longer for a doctor’s consultation in primary care had a reduced PSS score, whereas caregivers who were satisfied with the waiting time in primary care had higher PSS scores. At the secondary care level, caregivers who possessed at least a diploma had reduced PSS scores, whereas caregivers who were satisfied with both doctors’ consultation times and occupational therapy appointments had higher PSS scores. At the tertiary care level, caregivers with an underlying medical problem and who had children undergoing occupational therapy for two months or more had reduced PSS scores. Nevertheless, the analysis showed that caregivers who were concerned with their children’s sleeping problems, who had been informed about parental support, who were satisfied with speech and occupational therapy appointments, who were satisfied with waiting times at tertiary care clinics, and who were satisfied with their doctor’s knowledge and experience had higher PSS scores. Conclusions: This study elucidated the importance of understanding caregivers’ satisfaction in attaining care for their ASD children and highlighted the need to promote factors that would increase caregivers’ satisfaction with current ASD services. © 2019 by the authors. Licensee MDPI, Basel, Switzerland. |
Ting, J H P; Yeo, K J Exploration of parents’ perceptions on social skills displayed by children with autism spectrum disorder Journal Article International Journal of Recent Technology and Engineering, 8 (1), pp. 313-321, 2019, ISSN: 22773878, (cited By 0). Abstract | Links | BibTeX | Tags: @article[if lt IE 9]>
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issn = fusion-columns 9, year = fusion-columns 8, date = fusion-columns 7, journal = fusion-columns 6, volume = fusion-columns 5, number = fusion-columns 4, pages = fusion-columns 3, publisher = fusion-columns 2, abstract = fusion-columns 1, note = fusion-columns 0, keywords = {}, pubstate = fusion-row 9, tppubtype = fusion-row 8 } A common symptom noted amongst children diagnosed with Autism Spectrum Disorder (ASD) refers to social skills impairment. The level of impaired social skills exerted by children with ASD relies on the disorder severity. As such, this research looked into the parents’ perceptions towards social skills exerted by children with ASD. Hence, interview sessions with semi-structured layout were carried out with ten parent who had children diagnosed with ASD. All interview sessions were recorded, which were later transcribed and coded using Nvivo11. Next, the interview transcriptions were discussed with the parents for clarification and accuracy of details. The study outcomes revealed several common features related to ASD, which are lacking social initiation, limited eye contact, poor social communication, limited joint attention, dysregulated emotions, and poor response towards social cues. Conclusively, children diagnosed with ASD displayed discrepancies in social skills, particularly in communication, social motivation, social awareness, autism mannerism, and social cognition. Few interventions suggested by parents to enhance children’s social skills at home were discussed. © BEIESP. |
Shamsudin, I D; Yu, M -L; Brown, T Translation, Cross-Cultural Adaptation and Validation of the Quality of Life in Autism Questionnaire (QoLA) from English into the Malay Language Journal Article Journal of Occupational Therapy, Schools, and Early Intervention, 12 (2), pp. 253-272, 2019, ISSN: 19411243, (cited By 0). Abstract | Links | BibTeX | Tags: @article fusion-row 7, author = fusion-row 6, url = fusion-row 5, doi = fusion-row 4, issn = fusion-row 3, year = fusion-row 2, date = fusion-row 1, journal = fusion-row 0, volume = fusion-footer-widget-area 9, number = fusion-footer-widget-area 8, pages = fusion-footer-widget-area 7, publisher = fusion-footer-widget-area 6, abstract = fusion-footer-widget-area 5, note = fusion-footer-widget-area 4, keywords = {}, pubstate = fusion-footer-widget-area 3, tppubtype = fusion-footer-widget-area 2 } Parents of children with autism spectrum disorder (ASD) often experience a lower quality of life, which impacts on their children’s care, functioning and outcome and requires assessment and monitoring. Malaysia is a country presenting with an increasing prevalence of ASD and needs a linguistically and culturally appropriate quality of life measurement for parents of children with ASD. The Quality of Life in Autism Questionnaire (QoLA) is a validated ASD-specific quality of life measure in English. This paper describes the translation and the cross-cultural adaptation process of the QoLA from English into Malay. The translated Malay version of QoLA exhibited reasonable levels of internal consistency, cross-cultural validity, face and content validity; and is ready to be used with Malay speakers. © 2018, © 2018 Taylor & Francis. |
Adib, N A N; Ibrahim, M I; Rahman, A A; Bakar, R S; Yahaya, N A; Hussin, S; Mansor, Wan W N A Perceived stress among caregivers of children with autism spectrum disorder: A state-wide study Journal Article International Journal of Environmental Research and Public Health, 16 (8), 2019, ISSN: 16617827, (cited By 0). Abstract | Links | BibTeX | Tags: Adaptation, Adolescent, Adult, Article, Autism, Autism Spectrum Disorders, Caregiver, Caregiver Burden, Child Care, Children, Coping Behaviour, Cross-Sectional Study, Female, Follow Up, Health Care, Health Care Access, Human, Infant, Learning Disorder, Malaysia, Male, Mental Stress, Middle Aged, Multiple Linear Regression Analysis, Newborn, Normal Human, Patient Transport, Perceived Stress Scale, Prediction, Preschool, Preschool Child, Psychological, Psychology, Psychometrics, Psychometry, Quality of Life, Stress, Tertiary Care Center, University Hospital @article fusion-footer-widget-area 1, author = fusion-footer-widget-area 0, url = fusion-fusion-copyright-content 9, doi = fusion-fusion-copyright-content 8, issn = fusion-fusion-copyright-content 7, year = fusion-fusion-copyright-content 6, date = fusion-fusion-copyright-content 5, journal = fusion-fusion-copyright-content 4, volume = fusion-fusion-copyright-content 3, number = fusion-fusion-copyright-content 2, publisher = fusion-fusion-copyright-content 1, abstract = fusion-fusion-copyright-content 0, note = fusion-row 9, keywords = fusion-row 8, pubstate = fusion-row 7, tppubtype = fusion-row 6 } Background: Caregivers of children with autism spectrum disorder (ASD) experience increased stress and more significant negative caregiving consequences than those with typically developing children. There is a lack of studies specifically focusing on stress among caregivers with ASD children in Asian countries. The current study examines levels of perceived stress and factors associated with it among caregivers in Kelantan, Malaysia. Methods: In a cross-sectional study, the Malay version of the Perceived Stress Scale (PSS) was administered to 227 caregivers of children with ASD. The caregivers were recruited from ASD databases in four tertiary hospitals in Kelantan and a meeting was set up during the child’s follow-up in the clinic. Multiple linear regression analyses were applied to determine the predictors of perceived stress. Results: The mean total perceived stress score was 20.84 (4.72). This was considered higher than average. Higher perceived stress was significantly predicted among caregivers who live far from the health institution, caregivers who do not own transportation to bring the child to the treatment center, and caregivers who have an ASD child with a learning disability. Conclusion: Caregivers of an ASD child perceived significant stress while taking care of their children. Institutions should alleviate the factors that were predicted to increase the caregivers’ perceived stress to improve the quality of the lives of children and ASD families as a whole. © 2019 by the authors. Licensee MDPI, Basel, Switzerland. |
Liu, Y -W; Liong, M T; Chung, Y -C E; Huang, H -Y; Peng, W -S; Cheng, Y -F; Lin, Y -S; Wu, Y -Y; Tsai, Y -C Nutrients, 11 (4), 2019, ISSN: 20726643, (cited By 4). Abstract | Links | BibTeX | Tags: Aberrant Behavior Checklist Taiwan version, Adolescent, Age, Age Factors, Aggression, Anxiety, Article, Attention Deficit Disorder, Autism, Autism Behavior Checklist, Autism Diagnostic Interview Revised, Autism Spectrum Disorders, Child Behaviour, Child Behaviour Checklist, Children, Clinical Global Impression Scale, Communication Disorder, Controlled Study, Double Blind Procedure, Double-Blind Method, Female, Generalized Anxiety Disorder, Human, Impulsiveness, Lactobacillus Plantarum, Male, Physiology, Placebo, Placebos, Posttraumatic Stress Disorder, Probiotic Agent, Probiotics, Psychology, Questionnaires, Randomized Controlled Trial, Rating Scale, School Child, Scoring System, Social Behaviour, Social Interactions, Social Problem, Social Responsiveness Scale, Surveys, Swanson Nolan and Pelham IV Assessment, Synaptosomal Associated Protein 23, Taiwan @article fusion-row 5, author = fusion-row 4, url = fusion-row 3, doi = fusion-row 2, issn = fusion-row 1, year = fusion-row 0, date = #footer 9, journal = #footer 8, volume = #footer 7, number = #footer 6, publisher = #footer 5, abstract = #footer 4, note = #footer 3, keywords = #footer 2, pubstate = #footer 1, tppubtype = #footer 0 } This four-week, randomized, double-blind, placebo-controlled study investigated the effects of Lactobacillus plantarum PS128 (PS128) on boys with autism spectrum disorder (ASD) aged 7-15 in Taiwan. All subjects fulfilled the criteria for ASD diagnosis of DSM-V and the Autism Diagnostic Interview-Revised (ADI-R). Questionnaires used for the primary outcome measure include the Autism Behavior Checklist-Taiwan version (ABC-T), the Social Responsiveness Scale (SRS) and the Child Behavior Checklist (CBCL). The Swanson, Nolan, and Pelham-IV-Taiwan version (SNAP-IV) and the Clinical Global Impression-improvement (CGI-I) were used for the secondary outcome measure. The results showed that PS128 ameliorated opposition/defiance behaviors, and that the total score of SNAP-IV for younger children (aged 7−12) improved significantly compared with the placebo group. Additionally, several elements were also notably improved in the PS128 group after 28-day consumption of PS128. Further studies are needed to better clarify the effects of PS128 for younger children with ASD on broader symptoms. © 2019 by the authors. Licensee MDPI, Basel, Switzerland. |
Razi, N I M; Rahman, A W A; Kamaruddin, N Resting state electroencephalogram in autism spectrum disorder identification based on neuro-physiological interface of affect (NPIA) modelling Journal Article Journal of Computational and Theoretical Nanoscience, 16 (3), pp. 1190-1195, 2019, ISSN: 15461955, (cited By 1). Abstract | Links | BibTeX | Tags: @article fusion-footer 9, author = fusion-footer 8, url = fusion-footer 7, doi = fusion-footer 6, issn = fusion-footer 5, year = fusion-footer 4, date = fusion-footer 3, journal = fusion-footer 2, volume = fusion-footer 1, number = fusion-footer 0, pages = wrapper 9, publisher = wrapper 8, abstract = wrapper 7, note = wrapper 6, keywords = {}, pubstate = wrapper 5, tppubtype = wrapper 4 } Children with autism spectrum disorder (ASD) is likely to have repetitive and restricted repertoire in its behaviors, activities and interests. Early detection and intervention of ASD can help these children to lead an almost normal life. Thus it is important to ensure that early detection of such ASD preschoolers can be carried out. The brain connectivity of ASD can be achieved better by capturing and analyzing through the EEG and machine learning. In this paper we presented both the time domain approach, which were used by most researchers to identify ASD and also the neuro-physiological interface of affect (NPIA) at resting state. There seems to be consistency in results based on the NPIA at resting state for eyes opened and eyes closed while using time domain approach shows otherwise. Therefore, both models can be used to have a better accuracy in diagnosing an ASD. Future works also can have the NPIA model approaches on the other learning disabilities. Copyright © 2019 American Scientific Publishers All rights reserved. |
Pramudya, G; Sedek, M; Shahbodin, F; Amran, A C; Ruslan, S N A Computer-assisted intervention (CAI) to enhance mathematical learning of autistic students: A case study in Melaka Journal Article Humanities and Social Sciences Reviews, 7 (2), pp. 196-203, 2019, ISSN: 23956518, (cited By 0). Abstract | Links | BibTeX | Tags: @article wrapper 3, author = wrapper 2, url = wrapper 1, doi = wrapper 0, issn = #boxed-wrapper 9, year = #boxed-wrapper 8, date = #boxed-wrapper 7, journal = #boxed-wrapper 6, volume = #boxed-wrapper 5, number = #boxed-wrapper 4, pages = #boxed-wrapper 3, publisher = #boxed-wrapper 2, abstract = #boxed-wrapper 1, note = #boxed-wrapper 0, keywords = {}, pubstate = Instagram Feed JS 9, tppubtype = Instagram Feed JS 8 } Purpose of the study: To evaluate the efficacy of a CAI called MathTutor in helping autistic students to learn addition in mathematics. Methodology: A pre-post-test experimental model was employed in the study. The study participants included three autistic male students who possessed all the prerequisite skills. Main findings and novelty: The study participants were found to have been benefitted which indicates that MathTutor improves their learning abilities as an effective instructional strategy. The use of CAI enabled the participants to memorise their lessons and actively take part during the entire lesson. Applications of this study: The study is beneficial for people involved in caring for autistic students with the help of computer assisted application. This will ease the burden of the carer takers of autistic children in dealing with their conditions while at the same enabling them to navigate the world. © Pramudya et al. |
Pichitpunpong, C; Thongkorn, S; Kanlayaprasit, S; Yuwattana, W; Plaingam, W; Sangsuthum, S; Aizat, W M; Baharum, S N; Tencomnao, T; Hu, V W; Sarachana, T PLoS ONE, 14 (3), 2019, ISSN: 19326203, (cited By 4). Abstract | Links | BibTeX | Tags: Article, Autism, Autism Spectrum Disorders, Binding Protein, Biological Marker, Biomarkers, Cell Line, Controlled Study, Developmental Disorders, Developmental Language Disorder, Diazepam Binding Inhibitor, Diazepam Binding Inhibitor Protein, Disease Severity, Female, Genetic Analysis, Human, Human Cell, Inflammation, Language Development Disorders, Language Disability, Liquid Chromatography-Mass Spectrometry, Lymphoblastoid Cell, Major Clinical Study, Male, Metabolism, Phenotype, Protein Analysis, Protein Expression, Protein Function, Proteome, Proteomics, Transcription Regulation, Transcriptome, Unclassified Drug, Western Blotting @article Instagram Feed JS 7, author = Instagram Feed JS 6, url = Instagram Feed JS 5, doi = Instagram Feed JS 4, issn = Instagram Feed JS 3, year = Instagram Feed JS 2, date = Instagram Feed JS 1, journal = Instagram Feed JS 0, volume = {14}, number = {3}, publisher = {Public Library of Science}, abstract = {Background The mechanisms underlying autism spectrum disorder (ASD) remain unclear, and clinical biomarkers are not yet available for ASD. Differences in dysregulated proteins in ASD have shown little reproducibility, which is partly due to ASD heterogeneity. Recent studies have demonstrated that subgrouping ASD cases based on clinical phenotypes is useful for identifying candidate genes that are dysregulated in ASD subgroups. However, this strategy has not been employed in proteome profiling analyses to identify ASD biomarker proteins for specific subgroups. Methods We therefore conducted a cluster analysis of the Autism Diagnostic Interview-Revised (ADI-R) scores from 85 individuals with ASD to predict subgroups and subsequently identified dysregulated genes by reanalyzing the transcriptome profiles of individuals with ASD and unaffected individuals. Proteome profiling of lymphoblastoid cell lines from these individuals was performed via 2D-gel electrophoresis, and then mass spectrometry. Disrupted proteins were identified and compared to the dysregulated transcripts and reported dysregulated proteins from previous proteome studies. Biological functions were predicted using the Ingenuity Pathway Analysis (IPA) program. Selected proteins were also analyzed by Western blotting. Results The cluster analysis of ADI-R data revealed four ASD subgroups, including ASD with severe language impairment, and transcriptome profiling identified dysregulated genes in each subgroup. Screening via proteome analysis revealed 82 altered proteins in the ASD subgroup with severe language impairment. Eighteen of these proteins were further identified by nano-LC-MS/MS. Among these proteins, fourteen were predicted by IPA to be associated with neurological functions and inflammation. Among these proteins, diazepam-binding inhibitor (DBI) protein was confirmed by Western blot analysis to be expressed at significantly decreased levels in the ASD subgroup with severe language impairment, and the DBI expression levels were correlated with the scores of several ADI-R items. Conclusions By subgrouping individuals with ASD based on clinical phenotypes, and then performing an integrated transcriptome-proteome analysis, we identified DBI as a novel candidate protein for ASD with severe language impairment. The mechanisms of this protein and its potential use as an ASD biomarker warrant further study. © 2019 Pichitpunpong et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.}, note = {cited By 4}, keywords = {Article, Autism, Autism Spectrum Disorders, Binding Protein, Biological Marker, Biomarkers, Cell Line, Controlled Study, Developmental Disorders, Developmental Language Disorder, Diazepam Binding Inhibitor, Diazepam Binding Inhibitor Protein, Disease Severity, Female, Genetic Analysis, Human, Human Cell, Inflammation, Language Development Disorders, Language Disability, Liquid Chromatography-Mass Spectrometry, Lymphoblastoid Cell, Major Clinical Study, Male, Metabolism, Phenotype, Protein Analysis, Protein Expression, Protein Function, Proteome, Proteomics, Transcription Regulation, Transcriptome, Unclassified Drug, Western Blotting}, pubstate = {published}, tppubtype = {article} } Background The mechanisms underlying autism spectrum disorder (ASD) remain unclear, and clinical biomarkers are not yet available for ASD. Differences in dysregulated proteins in ASD have shown little reproducibility, which is partly due to ASD heterogeneity. Recent studies have demonstrated that subgrouping ASD cases based on clinical phenotypes is useful for identifying candidate genes that are dysregulated in ASD subgroups. However, this strategy has not been employed in proteome profiling analyses to identify ASD biomarker proteins for specific subgroups. Methods We therefore conducted a cluster analysis of the Autism Diagnostic Interview-Revised (ADI-R) scores from 85 individuals with ASD to predict subgroups and subsequently identified dysregulated genes by reanalyzing the transcriptome profiles of individuals with ASD and unaffected individuals. Proteome profiling of lymphoblastoid cell lines from these individuals was performed via 2D-gel electrophoresis, and then mass spectrometry. Disrupted proteins were identified and compared to the dysregulated transcripts and reported dysregulated proteins from previous proteome studies. Biological functions were predicted using the Ingenuity Pathway Analysis (IPA) program. Selected proteins were also analyzed by Western blotting. Results The cluster analysis of ADI-R data revealed four ASD subgroups, including ASD with severe language impairment, and transcriptome profiling identified dysregulated genes in each subgroup. Screening via proteome analysis revealed 82 altered proteins in the ASD subgroup with severe language impairment. Eighteen of these proteins were further identified by nano-LC-MS/MS. Among these proteins, fourteen were predicted by IPA to be associated with neurological functions and inflammation. Among these proteins, diazepam-binding inhibitor (DBI) protein was confirmed by Western blot analysis to be expressed at significantly decreased levels in the ASD subgroup with severe language impairment, and the DBI expression levels were correlated with the scores of several ADI-R items. Conclusions By subgrouping individuals with ASD based on clinical phenotypes, and then performing an integrated transcriptome-proteome analysis, we identified DBI as a novel candidate protein for ASD with severe language impairment. The mechanisms of this protein and its potential use as an ASD biomarker warrant further study. © 2019 Pichitpunpong et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Hasan, C Z C; Jailani, R; Tahir, N M 2018-October , Institute of Electrical and Electronics Engineers Inc., 2019, ISSN: 21593442, (cited By 0). Abstract | Links | BibTeX | Tags: 10 Fold Cross Validation, 3D Modeling, Autism Spectrum Disorders, Biophysics, Clinical Decision Making, Computer Aided Diagnosis, Decision Making, Discriminant Analysis, Diseases, Gait Analysis, Gait Classification, Ground Reaction Forces, Neural Networks, Parameterization Techniques, Pattern Recognition, Petroleum Reservoir Evaluation, Program Diagnostics, Support Vector Machines, Targeted Treatment, Three-Dimensional @conference{Hasan20192436, title = {ANN and SVM Classifiers in Identifying Autism Spectrum Disorder Gait Based on Three-Dimensional Ground Reaction Forces}, author = {C Z C Hasan and R Jailani and N M Tahir}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063202256&doi=10.1109%2fTENCON.2018.8650468&partnerID=40&md5=c697d0c43ebd77d76d74cb3726872f42}, doi = {10.1109/TENCON.2018.8650468}, issn = {21593442}, year = {2019}, date = {2019-01-01}, journal = {IEEE Region 10 Annual International Conference, Proceedings/TENCON}, volume = {2018-October}, pages = {2436-2440}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {Autism spectrum disorder (ASD) is a complex and lifelong neurodevelopmental condition that occurs in early childhood and is associated with unusual movement and gait disturbances. An automated and accurate recognition of ASD gait provides assistance in diagnosis and clinical decision-making as well as improving targeted treatment. This paper explores the use of two well-known machine learning classifiers, artificial neural network (ANN) and support vector machine (SVM) in distinguishing ASD and normal gait patterns based on prominent gait features derived from three-dimensional (3D) ground reaction forces (GRFs) data. The 3D GRFs data of 30 children with ASD and 30 typically developing children were obtained using two force plates during self-determined speed of barefoot walking. Time-series parameterization techniques were applied to the 3D GRFs waveforms to extract the significant gait features. The stepwise method of discriminant analysis (SWDA) was employed to determine the dominant GRF gait features in order to classify ASD and typically developing groups. The 10-fold cross-validation test results indicate that the ANN model with three dominant GRF input features outperformed the kernel-based SVM models with 93.3% accuracy, 96.7% sensitivity, and 90.0% specificity. The findings of this study demonstrate the reliability of using the 3D GRF input features, in combination with SWDA feature selection and ANN classification model as an appropriate method that may be beneficial for the diagnosis of ASD gait as well as for evaluation purpose of the treatment programs. © 2018 IEEE.}, note = {cited By 0}, keywords = {10 Fold Cross Validation, 3D Modeling, Autism Spectrum Disorders, Biophysics, Clinical Decision Making, Computer Aided Diagnosis, Decision Making, Discriminant Analysis, Diseases, Gait Analysis, Gait Classification, Ground Reaction Forces, Neural Networks, Parameterization Techniques, Pattern Recognition, Petroleum Reservoir Evaluation, Program Diagnostics, Support Vector Machines, Targeted Treatment, Three-Dimensional}, pubstate = {published}, tppubtype = {conference} } Autism spectrum disorder (ASD) is a complex and lifelong neurodevelopmental condition that occurs in early childhood and is associated with unusual movement and gait disturbances. An automated and accurate recognition of ASD gait provides assistance in diagnosis and clinical decision-making as well as improving targeted treatment. This paper explores the use of two well-known machine learning classifiers, artificial neural network (ANN) and support vector machine (SVM) in distinguishing ASD and normal gait patterns based on prominent gait features derived from three-dimensional (3D) ground reaction forces (GRFs) data. The 3D GRFs data of 30 children with ASD and 30 typically developing children were obtained using two force plates during self-determined speed of barefoot walking. Time-series parameterization techniques were applied to the 3D GRFs waveforms to extract the significant gait features. The stepwise method of discriminant analysis (SWDA) was employed to determine the dominant GRF gait features in order to classify ASD and typically developing groups. The 10-fold cross-validation test results indicate that the ANN model with three dominant GRF input features outperformed the kernel-based SVM models with 93.3% accuracy, 96.7% sensitivity, and 90.0% specificity. The findings of this study demonstrate the reliability of using the 3D GRF input features, in combination with SWDA feature selection and ANN classification model as an appropriate method that may be beneficial for the diagnosis of ASD gait as well as for evaluation purpose of the treatment programs. © 2018 IEEE. |
Mohamad, F H; Has, A T C The α5-Containing GABA A Receptors—a Brief Summary Journal Article Journal of Molecular Neuroscience, 67 (2), pp. 343-351, 2019, ISSN: 08958696, (cited By 1). Abstract | Links | BibTeX | Tags: 4 Aminobutyric Acid, 4 Aminobutyric Acid A Receptor, Alpha5 Containing 4 Aminobutyric Acid A Receptor, Animals, Autism, Brain, Cognitive Defect, Cognitive Dysfunction, Drug Effect, GABA Agents, GABA-A, GABAergic Receptor Affecting Agent, Genetics, Human, Metabolism, Nonhuman, Protein Subunit, Protein Subunits, Receptors, Review, Schizophrenia, Unclassified Drug @article{Mohamad2019343, title = {The α5-Containing GABA A Receptors—a Brief Summary}, author = {F H Mohamad and A T C Has}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059596842&doi=10.1007%2fs12031-018-1246-4&partnerID=40&md5=7b2ba0dc86c6c3f890f226cad8195ee5}, doi = {10.1007/s12031-018-1246-4}, issn = {08958696}, year = {2019}, date = {2019-01-01}, journal = {Journal of Molecular Neuroscience}, volume = {67}, number = {2}, pages = {343-351}, publisher = {Springer New York LLC}, abstract = {GABA A receptors are the major inhibitory neurotransmitter receptor in the human brain. The receptors are assembled from combination of protein subunits in pentameric complex which may consist of α1–6, β1–3, γ1–3, ρ1–3, δ, ε, θ, or π subunits. There are a theoretical > 150,000 possible assemblies and arrangements of GABA A subunits, although only a few combinations have been found in human with the most dominant consists of 2α1, 2β2, and 1γ2 in a counterclockwise arrangement as seen from the synaptic cleft. The receptors also possess binding sites for various unrelated substances including benzodiazepines, barbiturates, and anesthetics. The α5-containing GABA A Rs only make up ≤ 5% of the entire receptor population, but up to 25% of the receptor subtype is located in the crucial learning and memory-associated area of the brain—the hippocampus, which has ignited myriads of hypotheses and theories in regard to its role. As well as exhibiting synaptic phasic inhibition, the α5-containing receptors are also extrasynaptic and mediate tonic inhibition with continuously occurring smaller amplitude. Studies on negative-allosteric modulators for reducing this tonic inhibition have been shown to enhance learning and memory in neurological disorders such as schizophrenia, Down syndrome, and autism with a possible alternative benzodiazepine binding site. Therefore, a few α5 subunit-specific compounds have been developed to address these pharmacological needs. With its small population, the α5-containing receptors could be the key and also the answer for many untreated cognitive dysfunctions and disorders. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.}, note = {cited By 1}, keywords = {4 Aminobutyric Acid, 4 Aminobutyric Acid A Receptor, Alpha5 Containing 4 Aminobutyric Acid A Receptor, Animals, Autism, Brain, Cognitive Defect, Cognitive Dysfunction, Drug Effect, GABA Agents, GABA-A, GABAergic Receptor Affecting Agent, Genetics, Human, Metabolism, Nonhuman, Protein Subunit, Protein Subunits, Receptors, Review, Schizophrenia, Unclassified Drug}, pubstate = {published}, tppubtype = {article} } GABA A receptors are the major inhibitory neurotransmitter receptor in the human brain. The receptors are assembled from combination of protein subunits in pentameric complex which may consist of α1–6, β1–3, γ1–3, ρ1–3, δ, ε, θ, or π subunits. There are a theoretical > 150,000 possible assemblies and arrangements of GABA A subunits, although only a few combinations have been found in human with the most dominant consists of 2α1, 2β2, and 1γ2 in a counterclockwise arrangement as seen from the synaptic cleft. The receptors also possess binding sites for various unrelated substances including benzodiazepines, barbiturates, and anesthetics. The α5-containing GABA A Rs only make up ≤ 5% of the entire receptor population, but up to 25% of the receptor subtype is located in the crucial learning and memory-associated area of the brain—the hippocampus, which has ignited myriads of hypotheses and theories in regard to its role. As well as exhibiting synaptic phasic inhibition, the α5-containing receptors are also extrasynaptic and mediate tonic inhibition with continuously occurring smaller amplitude. Studies on negative-allosteric modulators for reducing this tonic inhibition have been shown to enhance learning and memory in neurological disorders such as schizophrenia, Down syndrome, and autism with a possible alternative benzodiazepine binding site. Therefore, a few α5 subunit-specific compounds have been developed to address these pharmacological needs. With its small population, the α5-containing receptors could be the key and also the answer for many untreated cognitive dysfunctions and disorders. © 2019, Springer Science+Business Media, LLC, part of Springer Nature. |
Jaafar, N H; Othman, A; Majid, N A; Harith, S; Zabidi-Hussin, Z Parent-report instruments for assessing feeding difficulties in children with neurological impairments: a systematic review Journal Article Developmental Medicine and Child Neurology, 61 (2), pp. 135-144, 2019, ISSN: 00121622, (cited By 1). Abstract | Links | BibTeX | Tags: Assessment of Humans, Autism, Behavioural Paediatric Feeding Assessment Scale, Caloric Intake, Child Behaviour, Child Parent Relation, Childhood Disease, Children, Children's Eating Behaviour Inventory, Complication, Construct Validity, Content Validity, Criterion Related Validity, Cystic Fibrosis, Eating Disorder, Enalapril Maleate, Eosinophilic Gastrointestinal Disorder, Esophagus Atresia, Feeding, Feeding and Eating Disorders, Feeding Behavior, Feeding Difficulty, Food Intake, Human, Nervous System Diseases, Neurologic Disease, Nutritional Assessment, Parents, Pediatric Assessment Scale for Severe Feeding Problem, Pediatric Eating Assessment Tool, Predictive Value, Preschool, Preschool Child, Priority Journal, Procedures, Psychology, Psychometrics, Psychometry, Quality of Life, Receiver Operating Characteristic, Review, Scoring System, Self Disclosure, Sensitivity and Specificity, Syndrome CHARGE, Systematic Review, Test Retest Reliability @article{Jaafar2019135, title = {Parent-report instruments for assessing feeding difficulties in children with neurological impairments: a systematic review}, author = {N H Jaafar and A Othman and N A Majid and S Harith and Z Zabidi-Hussin}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052789833&doi=10.1111%2fdmcn.13986&partnerID=40&md5=d02a2bfcd15a25988b9c23855cd87444}, doi = {10.1111/dmcn.13986}, issn = {00121622}, year = {2019}, date = {2019-01-01}, journal = {Developmental Medicine and Child Neurology}, volume = {61}, number = {2}, pages = {135-144}, publisher = {Blackwell Publishing Ltd}, abstract = {Aim: This study aimed to review the psychometric properties and clinical application of parent-report instruments that assess feeding difficulties in children with neurological impairments. Method: Papers were identified through five electronic databases based on 15 keywords and were included if they met the following criteria: published in English, described the implementation of parent-report instruments, and included children with neurological impairments (either in the report or a related study population). Results: In total, 1220 relevant abstracts were screened and 22 full-text articles were evaluated. The following six parent-report instruments met the inclusion criteria: (1) Screening Tool of Feeding Problems applied to children, (2) Paediatric Eating Assessment Tool, (3) Paediatric Assessment Scale for Severe Feeding Problems, (4) Montreal Children's Hospital Feeding Scale, (5) Children's Eating Behaviour Inventory, and (6) Behavioural Paediatric Feeding Assessment Scale (BPFAS). Based on comprehensive psychometric testing and consistently good results, the BPFAS was considered the most valid and reliable instrument. The BPFAS also showed good clinical applicability because it was readily available, required a short administration time, and used a simple scoring system. Interpretation: We reviewed the available parent-report instruments for assessing feeding difficulties in children with neurological impairments. The BPFAS had the best psychometric properties and clinical applicability. What this paper adds: Six parent-report instruments were suitable for assessing feeding in children with neurological impairments. The Behavioural Paediatric Feeding Assessment Scale (BPFAS) has the strongest psychometric properties. The BPFAS also has good clinical applicability. © 2018 Mac Keith Press}, note = {cited By 1}, keywords = {Assessment of Humans, Autism, Behavioural Paediatric Feeding Assessment Scale, Caloric Intake, Child Behaviour, Child Parent Relation, Childhood Disease, Children, Children's Eating Behaviour Inventory, Complication, Construct Validity, Content Validity, Criterion Related Validity, Cystic Fibrosis, Eating Disorder, Enalapril Maleate, Eosinophilic Gastrointestinal Disorder, Esophagus Atresia, Feeding, Feeding and Eating Disorders, Feeding Behavior, Feeding Difficulty, Food Intake, Human, Nervous System Diseases, Neurologic Disease, Nutritional Assessment, Parents, Pediatric Assessment Scale for Severe Feeding Problem, Pediatric Eating Assessment Tool, Predictive Value, Preschool, Preschool Child, Priority Journal, Procedures, Psychology, Psychometrics, Psychometry, Quality of Life, Receiver Operating Characteristic, Review, Scoring System, Self Disclosure, Sensitivity and Specificity, Syndrome CHARGE, Systematic Review, Test Retest Reliability}, pubstate = {published}, tppubtype = {article} } Aim: This study aimed to review the psychometric properties and clinical application of parent-report instruments that assess feeding difficulties in children with neurological impairments. Method: Papers were identified through five electronic databases based on 15 keywords and were included if they met the following criteria: published in English, described the implementation of parent-report instruments, and included children with neurological impairments (either in the report or a related study population). Results: In total, 1220 relevant abstracts were screened and 22 full-text articles were evaluated. The following six parent-report instruments met the inclusion criteria: (1) Screening Tool of Feeding Problems applied to children, (2) Paediatric Eating Assessment Tool, (3) Paediatric Assessment Scale for Severe Feeding Problems, (4) Montreal Children's Hospital Feeding Scale, (5) Children's Eating Behaviour Inventory, and (6) Behavioural Paediatric Feeding Assessment Scale (BPFAS). Based on comprehensive psychometric testing and consistently good results, the BPFAS was considered the most valid and reliable instrument. The BPFAS also showed good clinical applicability because it was readily available, required a short administration time, and used a simple scoring system. Interpretation: We reviewed the available parent-report instruments for assessing feeding difficulties in children with neurological impairments. The BPFAS had the best psychometric properties and clinical applicability. What this paper adds: Six parent-report instruments were suitable for assessing feeding in children with neurological impairments. The Behavioural Paediatric Feeding Assessment Scale (BPFAS) has the strongest psychometric properties. The BPFAS also has good clinical applicability. © 2018 Mac Keith Press |
Khowaja, K; Salim, S S; Al-Thani, D Institute of Electrical and Electronics Engineers Inc., 2019, ISBN: 9781538679661, (cited By 2). Abstract | Links | BibTeX | Tags: Autism Spectrum Disorders, Components, Diseases, Framework, Game Design, Games, Serious Games, Vocabulary @conference{Khowaja2019, title = {Components to design serious games for children with autism spectrum disorder (ASD) to learn vocabulary}, author = {K Khowaja and S S Salim and D Al-Thani}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062890872&doi=10.1109%2fICETAS.2018.8629208&partnerID=40&md5=277d4ff732687855a21405bf66efe9af}, doi = {10.1109/ICETAS.2018.8629208}, isbn = {9781538679661}, year = {2019}, date = {2019-01-01}, journal = {2018 IEEE 5th International Conference on Engineering Technologies and Applied Sciences, ICETAS 2018}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {Background: The research on the use of serious games to provide learning of skills to children with autism spectrum disorder (ASD) has increased in recent years. The use of serious games to provide vocabulary learning to children with ASD is still in infancy stage. Serious games are designed using a framework as a basis to use components in the game. However, there is no existing serious game design framework that can consider the needs of children with ASD.Objective: The objective of this study is to review components that could be useful in the design of serious game for children with ASD to learn vocabulary.Methods: The review of the literature on vocabulary learning of children with ASD and existing SGDFs was carried out to identify the components. The components have been reviewed from the perspective of 1) vocabulary learning of children with ASD in particular, 2) children with ASD in whole, 3) typical children and 4) game design in general.Results: A total of fifty components were found. The four components namely autism behaviours, strategies, instruction methods and modalities are related to children with ASD and their learning of vocabulary. The remaining components are based on the review of existing SGDFs. There were similarities in terms of use of components across the frameworks.Conclusion: The analysis of these components in the serious games developed for children with ASD shows its usability in designing games for these children. © 2018 IEEE.}, note = {cited By 2}, keywords = {Autism Spectrum Disorders, Components, Diseases, Framework, Game Design, Games, Serious Games, Vocabulary}, pubstate = {published}, tppubtype = {conference} } Background: The research on the use of serious games to provide learning of skills to children with autism spectrum disorder (ASD) has increased in recent years. The use of serious games to provide vocabulary learning to children with ASD is still in infancy stage. Serious games are designed using a framework as a basis to use components in the game. However, there is no existing serious game design framework that can consider the needs of children with ASD.Objective: The objective of this study is to review components that could be useful in the design of serious game for children with ASD to learn vocabulary.Methods: The review of the literature on vocabulary learning of children with ASD and existing SGDFs was carried out to identify the components. The components have been reviewed from the perspective of 1) vocabulary learning of children with ASD in particular, 2) children with ASD in whole, 3) typical children and 4) game design in general.Results: A total of fifty components were found. The four components namely autism behaviours, strategies, instruction methods and modalities are related to children with ASD and their learning of vocabulary. The remaining components are based on the review of existing SGDFs. There were similarities in terms of use of components across the frameworks.Conclusion: The analysis of these components in the serious games developed for children with ASD shows its usability in designing games for these children. © 2018 IEEE. |
Shahbodin, F; Mohd, C K N C K; Azni, A H; Jano, Z Visual perception games for autistic learners: Research findings Conference Association for Computing Machinery, 2019, ISBN: 9781450366212, (cited By 0). Abstract | Links | BibTeX | Tags: ADDIE Model, Autism, Autistic Children, Children with Autism, Conventional Methods, Diagnostic tools, Diseases, Education, Education Computing, Serious Games, Special Education, Students, Vision, Visual Perception @conference{Shahbodin201956, title = {Visual perception games for autistic learners: Research findings}, author = {F Shahbodin and C K N C K Mohd and A H Azni and Z Jano}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064943370&doi=10.1145%2f3314527.3314534&partnerID=40&md5=d8f7013f1b7932097d9c65379ec94aab}, doi = {10.1145/3314527.3314534}, isbn = {9781450366212}, year = {2019}, date = {2019-01-01}, journal = {ACM International Conference Proceeding Series}, pages = {56-60}, publisher = {Association for Computing Machinery}, abstract = {Early identification and diagnosis of autism is the key to minimize its negative effects and get the autistic children on the right path. This paper analyzed autism diagnostic tool using serious games technique namely Vi-Per Games. It is a tool for special education teachers to diagnose visual perception problems among autistic students. The development of the game is based on ADDIE model. The results show that the use of Vi-Per Games successfully assist and facilitate teachers when making a diagnosis of visual perception problems in autistic students, compared with conventional methods of diagnosis. Diagnosing visual perception problems using serious games gives teachers and students enjoyable experiences in a way that no other medium can offer. © 2019 Association for Computing Machinery.}, note = {cited By 0}, keywords = {ADDIE Model, Autism, Autistic Children, Children with Autism, Conventional Methods, Diagnostic tools, Diseases, Education, Education Computing, Serious Games, Special Education, Students, Vision, Visual Perception}, pubstate = {published}, tppubtype = {conference} } Early identification and diagnosis of autism is the key to minimize its negative effects and get the autistic children on the right path. This paper analyzed autism diagnostic tool using serious games technique namely Vi-Per Games. It is a tool for special education teachers to diagnose visual perception problems among autistic students. The development of the game is based on ADDIE model. The results show that the use of Vi-Per Games successfully assist and facilitate teachers when making a diagnosis of visual perception problems in autistic students, compared with conventional methods of diagnosis. Diagnosing visual perception problems using serious games gives teachers and students enjoyable experiences in a way that no other medium can offer. © 2019 Association for Computing Machinery. |
Mohd, C K N C K; Shahbodin, F; Azni, A H; Jano, Z Visual perception games for autistic learners: Design & development Conference Association for Computing Machinery, 2019, ISBN: 9781450366212, (cited By 0). Abstract | Links | BibTeX | Tags: Autism Spectrum Disorders, Autistic Children, Children with Autism, Design and Development, Diagnosis, Diagnostic Products, Diagnostic tools, Diseases, Education, Education Computing, High Incidence, Information and Communications Technology, Information Use, Patient Treatment, Serious Games, Special Education, Students, Vision, Visual Perception @conference{Mohd20195b, title = {Visual perception games for autistic learners: Design & development}, author = {C K N C K Mohd and F Shahbodin and A H Azni and Z Jano}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064918100&doi=10.1145%2f3314527.3314533&partnerID=40&md5=a3c6394e2cd86d31a30ed2d1f3b6e1e6}, doi = {10.1145/3314527.3314533}, isbn = {9781450366212}, year = {2019}, date = {2019-01-01}, journal = {ACM International Conference Proceeding Series}, pages = {5-11}, publisher = {Association for Computing Machinery}, abstract = {The use of information communication technologies (ICTs) in therapy offers new perspectives for treating many domains in individuals with autism spectrum disorders (ASD) because it is used in many different ways and settings and they are attractive to the patients. Students with autism have a high incidence of visual perception problems. They often have difficulty recognizing, remembering, organizing and interpreting visual images. As a result, they are easily confused in situations where written or pictorial symbols are utilised for learning. The paper reported the design and development of autism diagnostic tool using serious games technique. It is a tool for special education teachers to diagnose visual perception problems among autistic students. The game is known as Vi-Per Games. A diagnostic tool known as Vi-Per Games has been developed based on ADDIE model. Vi-Per Games is able to diagnose autistic students without the needs for teachers to have some experience and knowledge of diagnosing visual perception. This prototype will be a high-tech solution to diagnose visual perception problems designed for autistic children. © 2019 Association for Computing Machinery.}, note = {cited By 0}, keywords = {Autism Spectrum Disorders, Autistic Children, Children with Autism, Design and Development, Diagnosis, Diagnostic Products, Diagnostic tools, Diseases, Education, Education Computing, High Incidence, Information and Communications Technology, Information Use, Patient Treatment, Serious Games, Special Education, Students, Vision, Visual Perception}, pubstate = {published}, tppubtype = {conference} } The use of information communication technologies (ICTs) in therapy offers new perspectives for treating many domains in individuals with autism spectrum disorders (ASD) because it is used in many different ways and settings and they are attractive to the patients. Students with autism have a high incidence of visual perception problems. They often have difficulty recognizing, remembering, organizing and interpreting visual images. As a result, they are easily confused in situations where written or pictorial symbols are utilised for learning. The paper reported the design and development of autism diagnostic tool using serious games technique. It is a tool for special education teachers to diagnose visual perception problems among autistic students. The game is known as Vi-Per Games. A diagnostic tool known as Vi-Per Games has been developed based on ADDIE model. Vi-Per Games is able to diagnose autistic students without the needs for teachers to have some experience and knowledge of diagnosing visual perception. This prototype will be a high-tech solution to diagnose visual perception problems designed for autistic children. © 2019 Association for Computing Machinery. |
Ishak, N I; Yusof, H.Md.; Sidek, S N; Rusli, N Robot selection in robotic intervention for ASD children Conference Institute of Electrical and Electronics Engineers Inc., 2019, ISBN: 9781538624715, (cited By 1). Abstract | Links | BibTeX | Tags: Autism Spectrum Disorders, Biomedical Engineering, Commercial Robots, Communication Skills, Early Intervention, Human Robot Interaction, Important Features, Recent Researches, Robotics, Social Interactions @conference{Ishak2019156, title = {Robot selection in robotic intervention for ASD children}, author = {N I Ishak and H.Md. Yusof and S N Sidek and N Rusli}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062769148&doi=10.1109%2fIECBES.2018.8626679&partnerID=40&md5=4ab38d1996ff4c48913864199d814cc6}, doi = {10.1109/IECBES.2018.8626679}, isbn = {9781538624715}, year = {2019}, date = {2019-01-01}, journal = {2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings}, pages = {156-160}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {This paper explains on the selection of a robot that is suitable for engagement with Autism Spectrum Disorder (ASD) children. Many robots were being developed to help these children to improve their behavior, communication skills, social interaction, joint attention and sensitivity. Recent researches done shown that a commercialize robot is better in early intervention therapy for the children because of its robustness and easily can be programmed by the parents and teachers. Instead, the physical appearance of the robot also plays an important feature for robot selection. Comparison studies were made between prototype robots that currently used in Human-Robot Interaction (HRI) and commercial robot. As a result, we proposed to have a commercial robot that is robust, simple, economical, durable and flexible to be changed to any desired form as our medium of interactions. © 2018 IEEE}, note = {cited By 1}, keywords = {Autism Spectrum Disorders, Biomedical Engineering, Commercial Robots, Communication Skills, Early Intervention, Human Robot Interaction, Important Features, Recent Researches, Robotics, Social Interactions}, pubstate = {published}, tppubtype = {conference} } This paper explains on the selection of a robot that is suitable for engagement with Autism Spectrum Disorder (ASD) children. Many robots were being developed to help these children to improve their behavior, communication skills, social interaction, joint attention and sensitivity. Recent researches done shown that a commercialize robot is better in early intervention therapy for the children because of its robustness and easily can be programmed by the parents and teachers. Instead, the physical appearance of the robot also plays an important feature for robot selection. Comparison studies were made between prototype robots that currently used in Human-Robot Interaction (HRI) and commercial robot. As a result, we proposed to have a commercial robot that is robust, simple, economical, durable and flexible to be changed to any desired form as our medium of interactions. © 2018 IEEE |
Ilias, K; Cornish, K; Park, M S; Toran, H; Golden, K J Frontiers in Psychology, 9 (JAN), 2019, ISSN: 16641078, (cited By 2). Abstract | Links | BibTeX | Tags: @article{Ilias2019, title = {Risk and resilience among mothers and fathers of primary school age children with ASD in Malaysia: A qualitative constructive grounded theory approach}, author = {K Ilias and K Cornish and M S Park and H Toran and K J Golden}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059619693&doi=10.3389%2ffpsyg.2018.02275&partnerID=40&md5=2b56f8f5e16484cfed5317951169fb05}, doi = {10.3389/fpsyg.2018.02275}, issn = {16641078}, year = {2019}, date = {2019-01-01}, journal = {Frontiers in Psychology}, volume = {9}, number = {JAN}, publisher = {Frontiers Media S.A.}, abstract = {Little is known about the coping and resilience experiences of parents of children with autism spectrum disorder (ASD) in the Malaysian cultural context. This study utilized a qualitative methodological approach adopting constructive grounded theory. The study sought to address the lack of research to date exploring the risk and protective experiences that contribute to parental stress and resilience for parents of primary school age children with ASD in the Malaysian setting. Twenty-two parents of children with ASD (13 mothers and 9 fathers) participated in semi-structured interviews. A strength of the study was the inclusion of both mother and father participant perspectives. The interviews lasted 50-80 min (mean: 67.5 min). The 22 parents had a total of 16 children (12 males; 4 females) formally diagnosed with ASD. Child age ranged between 5 and 12 years (mean age: 8.44). Overall, analysis of the 22 interviews revealed four prominent themes - "initial reaction to child's ASD symptoms and diagnosis," "family life affected by a child with ASD," äwareness about ASD in Malaysia," and "coping strategies, wellbeing, and becoming resilient." The first three themes revolved around stress and adversity, and, the adaptability and acceptance of the parents. These processes illustrated the risks experienced by the parents of children with ASD in Malaysia. The last theme especially highlighted the strengths and determination of the parents and illustrated the protective experiences and processes that helped parents to develop and enhance resilience. Overall, the findings revealed that resilience develops synergistically and dynamically from both risk and protective experiences across different levels - individual, family, community, society and government. The findings motivated the development of our theoretical model of resilience that can help health and education professionals tailor assessment and interventions for parents of children with ASD in the Malaysian context. Clinical, policy, and research suggestions were discussed. © 2019 Ilias, Cornish, Park, Toran and Golden.}, note = {cited By 2}, keywords = {}, pubstate = {published}, tppubtype = {article} } Little is known about the coping and resilience experiences of parents of children with autism spectrum disorder (ASD) in the Malaysian cultural context. This study utilized a qualitative methodological approach adopting constructive grounded theory. The study sought to address the lack of research to date exploring the risk and protective experiences that contribute to parental stress and resilience for parents of primary school age children with ASD in the Malaysian setting. Twenty-two parents of children with ASD (13 mothers and 9 fathers) participated in semi-structured interviews. A strength of the study was the inclusion of both mother and father participant perspectives. The interviews lasted 50-80 min (mean: 67.5 min). The 22 parents had a total of 16 children (12 males; 4 females) formally diagnosed with ASD. Child age ranged between 5 and 12 years (mean age: 8.44). Overall, analysis of the 22 interviews revealed four prominent themes - "initial reaction to child's ASD symptoms and diagnosis," "family life affected by a child with ASD," äwareness about ASD in Malaysia," and "coping strategies, wellbeing, and becoming resilient." The first three themes revolved around stress and adversity, and, the adaptability and acceptance of the parents. These processes illustrated the risks experienced by the parents of children with ASD in Malaysia. The last theme especially highlighted the strengths and determination of the parents and illustrated the protective experiences and processes that helped parents to develop and enhance resilience. Overall, the findings revealed that resilience develops synergistically and dynamically from both risk and protective experiences across different levels - individual, family, community, society and government. The findings motivated the development of our theoretical model of resilience that can help health and education professionals tailor assessment and interventions for parents of children with ASD in the Malaysian context. Clinical, policy, and research suggestions were discussed. © 2019 Ilias, Cornish, Park, Toran and Golden. |
Khowaja, K; Salim, S S Serious Game for Children with Autism to Learn Vocabulary: An Experimental Evaluation Journal Article International Journal of Human-Computer Interaction, 35 (1), pp. 1-26, 2019, ISSN: 10447318, (cited By 13). Abstract | Links | BibTeX | Tags: Autism Spectrum Disorders, Children with Autism, Design and Development, Diseases, Experimental Evaluation, Game Prototypes, Games, Generic Components, Language Comprehensions, Serious Games, Vocabulary @article{Khowaja20191, title = {Serious Game for Children with Autism to Learn Vocabulary: An Experimental Evaluation}, author = {K Khowaja and S S Salim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041121490&doi=10.1080%2f10447318.2017.1420006&partnerID=40&md5=156c0d5a4f725ee03fcae97740a468c2}, doi = {10.1080/10447318.2017.1420006}, issn = {10447318}, year = {2019}, date = {2019-01-01}, journal = {International Journal of Human-Computer Interaction}, volume = {35}, number = {1}, pages = {1-26}, publisher = {Taylor and Francis Inc.}, abstract = {The use of serious games (SGs) to provide intervention for various skills to children with autism spectrum disorder (ASD) has increased in the recent years. However, the potential of these games has not been utilized to provide learning of vocabulary to children with ASD. In designing games for children with ASD, there is a need to consider components specifically from the perspectives of ASD and the generic components that can support from the theoretical, content, and game design aspects. In the absence of any existing framework to design games for children with ASD, this article first introduces a framework named serious game design framework (SGDF), constructed to provide support throughout the design process. This framework was constructed based on the extensive review of the literature on ASD and existing SGDFs. The article then focuses on the design and development of a SG prototype based on SGDF. An experimental evaluation prototype was conducted to examine the effectiveness using the withdrawal design of single-subject research design (SSRD) in improving the receptive identification of vocabulary items among children with autism before and after using the prototype. The receptive identification of vocabulary items is measured in terms of the number of correct responses given and the number of attempts made to identify the correct response. The pre- and post-evaluations of the SG prototype show that learning of vocabulary items among children with ASD improved after using the game and they retained items at the end of weeks 1 and 2 following the withdrawal of intervention. © 2018, © 2018 Taylor & Francis Group, LLC.}, note = {cited By 13}, keywords = {Autism Spectrum Disorders, Children with Autism, Design and Development, Diseases, Experimental Evaluation, Game Prototypes, Games, Generic Components, Language Comprehensions, Serious Games, Vocabulary}, pubstate = {published}, tppubtype = {article} } The use of serious games (SGs) to provide intervention for various skills to children with autism spectrum disorder (ASD) has increased in the recent years. However, the potential of these games has not been utilized to provide learning of vocabulary to children with ASD. In designing games for children with ASD, there is a need to consider components specifically from the perspectives of ASD and the generic components that can support from the theoretical, content, and game design aspects. In the absence of any existing framework to design games for children with ASD, this article first introduces a framework named serious game design framework (SGDF), constructed to provide support throughout the design process. This framework was constructed based on the extensive review of the literature on ASD and existing SGDFs. The article then focuses on the design and development of a SG prototype based on SGDF. An experimental evaluation prototype was conducted to examine the effectiveness using the withdrawal design of single-subject research design (SSRD) in improving the receptive identification of vocabulary items among children with autism before and after using the prototype. The receptive identification of vocabulary items is measured in terms of the number of correct responses given and the number of attempts made to identify the correct response. The pre- and post-evaluations of the SG prototype show that learning of vocabulary items among children with ASD improved after using the game and they retained items at the end of weeks 1 and 2 following the withdrawal of intervention. © 2018, © 2018 Taylor & Francis Group, LLC. |
Selvaganapathi, G; Ahmed, Jinat J; Mathialagan, A G; Azra, N; Kularaja, K; Nazmul, M H M; Kumaraswamy, K; Thirupatharao, V; Dinesh, M; Harikrishnan, T Opcion, 35 (SpecialEdition24), pp. 690-712, 2019, ISSN: 10121587, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Selvaganapathi2019690, title = {Teachers' knowledge and perception towards children with an autism spectrum disorder [Conocimiento y percepción de los maestros hacia los niños con un trastorno del espectro autista]}, author = {G Selvaganapathi and J Jinat Ahmed and A G Mathialagan and N Azra and K Kularaja and M H M Nazmul and K Kumaraswamy and V Thirupatharao and M Dinesh and T Harikrishnan}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077548848&partnerID=40&md5=d8c8ee1a2ba01f933c373a9423f5210e}, issn = {10121587}, year = {2019}, date = {2019-01-01}, journal = {Opcion}, volume = {35}, number = {SpecialEdition24}, pages = {690-712}, publisher = {Universidad del Zulia}, abstract = {This study aims to assess teacher’s knowledge and perception towards children with autism spectrum disorder (ASD) in Malaysia. A cross-sectional study was done by using convenient sampling. Respondents that fulfill the inclusion & exclusion criteria were sent online validated questionnaire, data were analyzed using SPSS. As a result, only a few of the respondents have good knowledge of autism, however, more have a positive attitude towards autism. In conclusion, we found that teachers did, in fact, recognize their own lack of knowledge of ASD and this awareness co-existed with an interest in increasing their knowledge and skills in this area. © 2019, Universidad del Zulia. All rights reserved.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } This study aims to assess teacher’s knowledge and perception towards children with autism spectrum disorder (ASD) in Malaysia. A cross-sectional study was done by using convenient sampling. Respondents that fulfill the inclusion & exclusion criteria were sent online validated questionnaire, data were analyzed using SPSS. As a result, only a few of the respondents have good knowledge of autism, however, more have a positive attitude towards autism. In conclusion, we found that teachers did, in fact, recognize their own lack of knowledge of ASD and this awareness co-existed with an interest in increasing their knowledge and skills in this area. © 2019, Universidad del Zulia. All rights reserved. |
Al-Oran, H M; Lee, K; Tan, K -A; Lim, P Y Malaysian Journal of Medicine and Health Sciences, 15 (3), pp. 135-141, 2019, ISSN: 16758544, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Al-Oran2019135, title = {The effectiveness of educational programs on parenting stress and coping mechanism among parents of children with autism spectrum disorder: A systematic review}, author = {H M Al-Oran and K Lee and K -A Tan and P Y Lim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073681826&partnerID=40&md5=eedb70a745385b6f229fe267bcbef8ea}, issn = {16758544}, year = {2019}, date = {2019-01-01}, journal = {Malaysian Journal of Medicine and Health Sciences}, volume = {15}, number = {3}, pages = {135-141}, publisher = {UPM Press}, abstract = {The aim of this systematic review was to evaluate the effectiveness of educational programs on parenting stress and coping mechanism among parents of children with Autism Spectrum Disorder. Our current review retrieved the articles from databases such as CINAHL, Springer, Ovid, PubMed, Google Scholar, and EBSCO host. Only articles published between the years of 2000 and 2018 in these databases were recruited using keywords such as Autism Spectrum Disorder, education program, parenting stress, coping mechanism, and coping strategies. The search generated 17 articles; 8 articles were relevant. This systematic review provides an important opportunity to advance our understanding of the effectiveness of the educational program for reducing parenting stress and improving coping mechanism among parents of children with Autism Spectrum Disorder. Nurses could also have a pivotal role in delivering the educational program for parents of children with ASD. © 2019 UPM Press. All rights reserved.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } The aim of this systematic review was to evaluate the effectiveness of educational programs on parenting stress and coping mechanism among parents of children with Autism Spectrum Disorder. Our current review retrieved the articles from databases such as CINAHL, Springer, Ovid, PubMed, Google Scholar, and EBSCO host. Only articles published between the years of 2000 and 2018 in these databases were recruited using keywords such as Autism Spectrum Disorder, education program, parenting stress, coping mechanism, and coping strategies. The search generated 17 articles; 8 articles were relevant. This systematic review provides an important opportunity to advance our understanding of the effectiveness of the educational program for reducing parenting stress and improving coping mechanism among parents of children with Autism Spectrum Disorder. Nurses could also have a pivotal role in delivering the educational program for parents of children with ASD. © 2019 UPM Press. All rights reserved. |
Aziz, N S A; Ahmad, W F W; Hashim, A S A study on mobile applications developed for children with autism Journal Article Advances in Intelligent Systems and Computing, 843 , pp. 772-780, 2019, ISSN: 21945357, (cited By 0). Abstract | Links | BibTeX | Tags: Autism, Children with Autism, Communication Skills, Diseases, Education, Educational Applications, Mobile Applications, Mobile Computing, Mobile Learning, Mobile Technology, Neurological Disorders, Soft Computing @article{Aziz2019772, title = {A study on mobile applications developed for children with autism}, author = {N S A Aziz and W F W Ahmad and A S Hashim}, editor = {Gazem Busalim N A Mohammed F. Saeed F.}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053916134&doi=10.1007%2f978-3-319-99007-1_71&partnerID=40&md5=b09f02f61c16c40cd2e1f7ec90ab0b99}, doi = {10.1007/978-3-319-99007-1_71}, issn = {21945357}, year = {2019}, date = {2019-01-01}, journal = {Advances in Intelligent Systems and Computing}, volume = {843}, pages = {772-780}, publisher = {Springer Verlag}, abstract = {The emerging of mobile technology leads to the extensive used of mobile application for learning purposes of the children with autism. Autism is a neurological disorder that affects the children’s behavior and their ability to communicate and interact socially. A lot of studies have been conducted on using mobile application to assist the children with autism to increase their social and communication skills. Mobile applications are now widely used, not only for entertainment and social networking, but also for education. The used of mobile applications in education has extend from dictionaries to special purpose education. This paper reviews six mobile applications developed to assist the children with autism for various purposes. This review will provide a summary of initial studies and preliminary findings for future development of enhanced application. © Springer Nature Switzerland AG 2019.}, note = {cited By 0}, keywords = {Autism, Children with Autism, Communication Skills, Diseases, Education, Educational Applications, Mobile Applications, Mobile Computing, Mobile Learning, Mobile Technology, Neurological Disorders, Soft Computing}, pubstate = {published}, tppubtype = {article} } The emerging of mobile technology leads to the extensive used of mobile application for learning purposes of the children with autism. Autism is a neurological disorder that affects the children’s behavior and their ability to communicate and interact socially. A lot of studies have been conducted on using mobile application to assist the children with autism to increase their social and communication skills. Mobile applications are now widely used, not only for entertainment and social networking, but also for education. The used of mobile applications in education has extend from dictionaries to special purpose education. This paper reviews six mobile applications developed to assist the children with autism for various purposes. This review will provide a summary of initial studies and preliminary findings for future development of enhanced application. © Springer Nature Switzerland AG 2019. |
Amirrudin, S; Rahim, N A; Halim, H A; Jalaludin, I Social stories to enhance communicative strategies among autism spectrum disorder (ASD) children Journal Article Jurnal Komunikasi: Malaysian Journal of Communication, 35 (2), pp. 87-102, 2019, ISSN: 2289151X, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Amirrudin201987, title = {Social stories to enhance communicative strategies among autism spectrum disorder (ASD) children}, author = {S Amirrudin and N A Rahim and H A Halim and I Jalaludin}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069989063&doi=10.17576%2fJKMJC-2019-3502-06&partnerID=40&md5=f6678edd6fb48d2606dd5c65dd34d48c}, doi = {10.17576/JKMJC-2019-3502-06}, issn = {2289151X}, year = {2019}, date = {2019-01-01}, journal = {Jurnal Komunikasi: Malaysian Journal of Communication}, volume = {35}, number = {2}, pages = {87-102}, publisher = {Universiti Kebangsaan Malaysia Press}, abstract = {The use of strategies by children with developmental disabilities in repairing their communicative breakdowns has received little attention in the research literature to date. These children may also have fewer strategies available to them. By using Tarone’s Taxonomy (1980) of communicative strategies, this current study was trying to further unravel and discuss how children with autism spectrum disorder (ASD) could enhance their spoken communicative intent in conversing about moral values. Audiotaped, semi-structured conversational data was collected from four children (two low functioning autism and two Asperger Syndrome) with autism ASD. They were seven to nine years old from Sekolah Kebangsaan Desaminium, Seri Kembangan, Selangor. Two social stories were told to the subjects; Visiting atuk and nenek in Kampung and Being Kind to Animals with two moral values underpinned in each social story. Findings revealed that all four ASD children were using almost all the nine communicative strategies except for word coinage. The study concluded that Tarone’s Taxonomy (1980) of communicative strategies was really helpful in unravelling the communicative intent of a group of ASD children in talking about moral values based on the social stories told to them. Having said so, future research still needs to consider how these strategies or perhaps other communicative strategies could be used as attempts to repair communicative breakdowns among ASD children. It is hoped that the impairment in understanding others’ mind hinders the development of an intent-based moral judgment in ASD children. © 2019, Universiti Kebangsaan Malaysia Press. All rights reserved.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } The use of strategies by children with developmental disabilities in repairing their communicative breakdowns has received little attention in the research literature to date. These children may also have fewer strategies available to them. By using Tarone’s Taxonomy (1980) of communicative strategies, this current study was trying to further unravel and discuss how children with autism spectrum disorder (ASD) could enhance their spoken communicative intent in conversing about moral values. Audiotaped, semi-structured conversational data was collected from four children (two low functioning autism and two Asperger Syndrome) with autism ASD. They were seven to nine years old from Sekolah Kebangsaan Desaminium, Seri Kembangan, Selangor. Two social stories were told to the subjects; Visiting atuk and nenek in Kampung and Being Kind to Animals with two moral values underpinned in each social story. Findings revealed that all four ASD children were using almost all the nine communicative strategies except for word coinage. The study concluded that Tarone’s Taxonomy (1980) of communicative strategies was really helpful in unravelling the communicative intent of a group of ASD children in talking about moral values based on the social stories told to them. Having said so, future research still needs to consider how these strategies or perhaps other communicative strategies could be used as attempts to repair communicative breakdowns among ASD children. It is hoped that the impairment in understanding others’ mind hinders the development of an intent-based moral judgment in ASD children. © 2019, Universiti Kebangsaan Malaysia Press. All rights reserved. |
Mohamad, S P; Yusoff, M Y Z M; Adli, D S H; Golden, K J Mental health studies on the coping strategies of Muslim parents of children with autism spectrum disorder in Malaysia (a narrative review) Journal Article Malaysian Journal of Medicine and Health Sciences, 15 , pp. 168-177, 2019, ISSN: 16758544, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Mohamad2019168, title = {Mental health studies on the coping strategies of Muslim parents of children with autism spectrum disorder in Malaysia (a narrative review)}, author = {S P Mohamad and M Y Z M Yusoff and D S H Adli and K J Golden}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076964112&partnerID=40&md5=03c0db3f1ff75439090e2913f1d4aee0}, issn = {16758544}, year = {2019}, date = {2019-01-01}, journal = {Malaysian Journal of Medicine and Health Sciences}, volume = {15}, pages = {168-177}, publisher = {UPM Press}, abstract = {Poor mental health can affect a person’s quality of life and well-being, impacting cognitive, emotional, social, and physical functioning. Mental health difficulties have been found commonly in parents of children with autism spectrum disorder (ASD), who often struggle to cope with a range of challenges. These parents tend to have reduced overall wellbeing. This review study targeted an under-researched area, aiming to review mental health studies on the coping strategies used by Muslim parents of children with ASD in Malaysia, focusing on psychospiritual strategies. Journal articles were searched via Google Scholar, Science Direct, and Mendeley software online databases using relevant keywords. This narrative review identified 5 studies that examined parental coping, but only 4 reported the inclusion of Muslims. This review identified a gap in published knowledge regarding coping from a spiritual perspective in Muslim families of children with ASD in Malaysia and recommended future research from a biopsychosocial-spiritual perspective. © 2019 UPM Press. All rights reserved.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } Poor mental health can affect a person’s quality of life and well-being, impacting cognitive, emotional, social, and physical functioning. Mental health difficulties have been found commonly in parents of children with autism spectrum disorder (ASD), who often struggle to cope with a range of challenges. These parents tend to have reduced overall wellbeing. This review study targeted an under-researched area, aiming to review mental health studies on the coping strategies used by Muslim parents of children with ASD in Malaysia, focusing on psychospiritual strategies. Journal articles were searched via Google Scholar, Science Direct, and Mendeley software online databases using relevant keywords. This narrative review identified 5 studies that examined parental coping, but only 4 reported the inclusion of Muslims. This review identified a gap in published knowledge regarding coping from a spiritual perspective in Muslim families of children with ASD in Malaysia and recommended future research from a biopsychosocial-spiritual perspective. © 2019 UPM Press. All rights reserved. |
Low, H M; Lee, L W; Ahmad, Che A Knowledge and Attitudes of Special Education Teachers Towards the Inclusion of Students with Autism Spectrum Disorder Journal Article International Journal of Disability, Development and Education, 2019, ISSN: 1034912X, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Low2019, title = {Knowledge and Attitudes of Special Education Teachers Towards the Inclusion of Students with Autism Spectrum Disorder}, author = {H M Low and L W Lee and A Che Ahmad}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067077509&doi=10.1080%2f1034912X.2019.1626005&partnerID=40&md5=e48042b72f97bcec1c0467fae0dc9a34}, doi = {10.1080/1034912X.2019.1626005}, issn = {1034912X}, year = {2019}, date = {2019-01-01}, journal = {International Journal of Disability, Development and Education}, publisher = {Routledge}, abstract = {Despite many nations having policies that mandate inclusive education for students with Autism Spectrum Disorder (ASD), the levels of implementation vary. In recent years, there has been increasing recognition of the grassroots’ interpretation of inclusive education for students with ASD in order to identify local contextual barriers and enablers of inclusion. In line with this research agenda, a study was conducted with 87 special education teachers in Penang, Malaysia to identify factors integral to their attitudes towards inclusive education for students with ASD. The analysis, which considered demographic factors, knowledge of ASD and societal attitudes, pointed to societal attitudes as a strong predictor of the special education teachers’ perceptions towards inclusive education for students with ASD. Given the findings, the ways to promote inclusive education for students with ASD in Malaysia and other developing nations alike were discussed. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } Despite many nations having policies that mandate inclusive education for students with Autism Spectrum Disorder (ASD), the levels of implementation vary. In recent years, there has been increasing recognition of the grassroots’ interpretation of inclusive education for students with ASD in order to identify local contextual barriers and enablers of inclusion. In line with this research agenda, a study was conducted with 87 special education teachers in Penang, Malaysia to identify factors integral to their attitudes towards inclusive education for students with ASD. The analysis, which considered demographic factors, knowledge of ASD and societal attitudes, pointed to societal attitudes as a strong predictor of the special education teachers’ perceptions towards inclusive education for students with ASD. Given the findings, the ways to promote inclusive education for students with ASD in Malaysia and other developing nations alike were discussed. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. |
Basri, N A; Hashim, N N W N Stress in parents of children with autism: A Malaysian experience Journal Article Intellectual Discourse, 27 , pp. 923-943, 2019, ISSN: 01284878, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Basri2019923, title = {Stress in parents of children with autism: A Malaysian experience}, author = {N A Basri and N N W N Hashim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079409340&partnerID=40&md5=d6f7bb889a1b209adf3d32bd2d8c1887}, issn = {01284878}, year = {2019}, date = {2019-01-01}, journal = {Intellectual Discourse}, volume = {27}, pages = {923-943}, publisher = {International Islamic University Malaysia}, abstract = {This study examines differences in parental stress between parents of Autism Spectrum Disorder (ASD) children (n=21) and Typically Developed (TD) children (n=41) in Malaysia. This study also compares the ages of parents of ASD children with parents of TD children with stress as a variable in these parents. Parents completed the Parental Stress Index (brief Malay version) and a socio-demographic questionnaire. Parents with ASD children were found to be significantly more stressed compared to parents of TD children (p<0.001). Significant scores were also found in the Parent-Child Dysfunctional Interaction (P-CDI) sub-scale (p<0.001) as well as Difficult Child (DC) and Parental Distress (PD) sub-scales with lower significance (p<0.05). Results also indicate that the 30-35-year-old age group among ASD parents was significantly found to be more stressed compared with parents of TD children of the same ages. Implications of the findings regarding support and intervention for families with ASD are also discussed. Copyright © IIUM Press}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } This study examines differences in parental stress between parents of Autism Spectrum Disorder (ASD) children (n=21) and Typically Developed (TD) children (n=41) in Malaysia. This study also compares the ages of parents of ASD children with parents of TD children with stress as a variable in these parents. Parents completed the Parental Stress Index (brief Malay version) and a socio-demographic questionnaire. Parents with ASD children were found to be significantly more stressed compared to parents of TD children (p<0.001). Significant scores were also found in the Parent-Child Dysfunctional Interaction (P-CDI) sub-scale (p<0.001) as well as Difficult Child (DC) and Parental Distress (PD) sub-scales with lower significance (p<0.05). Results also indicate that the 30-35-year-old age group among ASD parents was significantly found to be more stressed compared with parents of TD children of the same ages. Implications of the findings regarding support and intervention for families with ASD are also discussed. Copyright © IIUM Press |
Mahayuddin, Z R; Mamat, N Implementing augmented reality (AR) on phonics-based literacy among children with autism Journal Article International Journal on Advanced Science, Engineering and Information Technology, 9 (6), pp. 2176-2181, 2019, ISSN: 20885334, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Mahayuddin20192176, title = {Implementing augmented reality (AR) on phonics-based literacy among children with autism}, author = {Z R Mahayuddin and N Mamat}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077525041&partnerID=40&md5=0167039bc176db575e5856526c68eed4}, issn = {20885334}, year = {2019}, date = {2019-01-01}, journal = {International Journal on Advanced Science, Engineering and Information Technology}, volume = {9}, number = {6}, pages = {2176-2181}, publisher = {Insight Society}, abstract = {The implementation of Augmented Reality (AR) technology in education has created an interesting approach to enhance the effectiveness and attractiveness of teaching and learning for students in real-life scenarios. This medium offers unique affordances, combining physical and virtual worlds, with continuous and implicit user control of the point of view and interactivity. This paper introduces the technology of augmented reality and its capabilities in facilitating children with autism. AR is a technology that overlays digital information on a live view of the physical world to create a blended experience. AR provides unique experiences and opportunities to learn and interact with information in the physical world. Hence, AR can be one of the effective technologies available in developing tools for teaching and learning with the combination of the virtual world and real objects such as transportation, fruits, numbers, and alphabets. This will facilitate the autistic child to recognize the abstract concepts of the real objects and their descriptions. The purpose of this paper was to investigate the use of AR on mobile devices in fostering literacy in academic and learning skills for children with autism using the phonics learning method. This prototype helps the autistic child to capture and associate the graphics or pictures of the surrounding objects so as improving the literacy and learning skills of the children. The results show that the children can pronounce and to distinguish between vowels ä", "i" and ü". The children are also able to answer most of the questions in the exercises provided. The interactivity between the children and the application raises their attention and focus mainly in literacy and learning skills. © 2019 Insight Society.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } The implementation of Augmented Reality (AR) technology in education has created an interesting approach to enhance the effectiveness and attractiveness of teaching and learning for students in real-life scenarios. This medium offers unique affordances, combining physical and virtual worlds, with continuous and implicit user control of the point of view and interactivity. This paper introduces the technology of augmented reality and its capabilities in facilitating children with autism. AR is a technology that overlays digital information on a live view of the physical world to create a blended experience. AR provides unique experiences and opportunities to learn and interact with information in the physical world. Hence, AR can be one of the effective technologies available in developing tools for teaching and learning with the combination of the virtual world and real objects such as transportation, fruits, numbers, and alphabets. This will facilitate the autistic child to recognize the abstract concepts of the real objects and their descriptions. The purpose of this paper was to investigate the use of AR on mobile devices in fostering literacy in academic and learning skills for children with autism using the phonics learning method. This prototype helps the autistic child to capture and associate the graphics or pictures of the surrounding objects so as improving the literacy and learning skills of the children. The results show that the children can pronounce and to distinguish between vowels ä", "i" and ü". The children are also able to answer most of the questions in the exercises provided. The interactivity between the children and the application raises their attention and focus mainly in literacy and learning skills. © 2019 Insight Society. |
Tan, S W; Abdullah, M H L; Daud, Mohd N F N Mobile games for children with autism spectrum disorder to support positive behavioural skills Journal Article Lecture Notes in Networks and Systems, 67 , pp. 475-490, 2019, ISSN: 23673370, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Tan2019475, title = {Mobile games for children with autism spectrum disorder to support positive behavioural skills}, author = {S W Tan and M H L Abdullah and N F N Mohd Daud}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066151031&doi=10.1007%2f978-981-13-6031-2_43&partnerID=40&md5=82a1e886e2354239d5891d9cc6c44f96}, doi = {10.1007/978-981-13-6031-2_43}, issn = {23673370}, year = {2019}, date = {2019-01-01}, journal = {Lecture Notes in Networks and Systems}, volume = {67}, pages = {475-490}, publisher = {Springer}, abstract = {Autism Spectrum Disorder (ASD) is one of the fastest growing disorders around the world. The increasing rate of occurrence in Malaysia is estimated to occur in 1 of every 625 children and has since become a great concern to the community. Due to insufficient resources to cater for the autism education services, ineffective teaching strategy, and inadequate good positive behavioural support, this work is initiated as a means of solution to aid this issue. Findings of how a mobile games application, “Safe and Sound” featuring personalisation avatar can foster autistic children’s positive behaviour in social practices aspect are reported in this paper. Mobile game applications are used to trigger the children’s imagination for cognitive development as it is expected to become reliable to support content for the children to learn and apply in real situations. This analysis is entirely focused on interactions in schools by examining data from classroom activities. Three findings were revealed: (i) Personalised avatar can trigger children with ASD interest, (ii) Personalised avatar can promote emotions and feelings among children with ASD, and (iii) Avatar can facilitate social interaction among children with ASD. Thus, mobile games that incorporate personalised avatar can support children with ASD, especially to facilitate their positive behavioural skills. © Springer Nature Singapore Pte Ltd. 2019.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } Autism Spectrum Disorder (ASD) is one of the fastest growing disorders around the world. The increasing rate of occurrence in Malaysia is estimated to occur in 1 of every 625 children and has since become a great concern to the community. Due to insufficient resources to cater for the autism education services, ineffective teaching strategy, and inadequate good positive behavioural support, this work is initiated as a means of solution to aid this issue. Findings of how a mobile games application, “Safe and Sound” featuring personalisation avatar can foster autistic children’s positive behaviour in social practices aspect are reported in this paper. Mobile game applications are used to trigger the children’s imagination for cognitive development as it is expected to become reliable to support content for the children to learn and apply in real situations. This analysis is entirely focused on interactions in schools by examining data from classroom activities. Three findings were revealed: (i) Personalised avatar can trigger children with ASD interest, (ii) Personalised avatar can promote emotions and feelings among children with ASD, and (iii) Avatar can facilitate social interaction among children with ASD. Thus, mobile games that incorporate personalised avatar can support children with ASD, especially to facilitate their positive behavioural skills. © Springer Nature Singapore Pte Ltd. 2019. |
Yap, C Y; Ng, K H; Cheah, Y; Lim, S Y; Price, J; Vries, De M App4Autism: An integrated assistive technology with heart rate monitoring for children with autism Journal Article Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 11870 LNCS , pp. 498-512, 2019, ISSN: 03029743, (cited By 0). Abstract | Links | BibTeX | Tags: Assistive Technology, Autism, Diseases, Early Childhoods, Heart, Heart Rate Monitoring, Mobile Applications, Mobile Computing, Patient Monitoring @article{Yap2019498, title = {App4Autism: An integrated assistive technology with heart rate monitoring for children with autism}, author = {C Y Yap and K H Ng and Y Cheah and S Y Lim and J Price and M De Vries}, editor = {Ahmad Smeaton Shih Velastin Terutoshi M N A F T K S T Badioze Zaman H. Mohamad Ali N.}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077911902&doi=10.1007%2f978-3-030-34032-2_44&partnerID=40&md5=6b173ff9add01d06fd0682db52f48d7b}, doi = {10.1007/978-3-030-34032-2_44}, issn = {03029743}, year = {2019}, date = {2019-01-01}, journal = {Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)}, volume = {11870 LNCS}, pages = {498-512}, publisher = {Springer}, abstract = {Autism Spectrum Disorder (ASD) is a neurological development disorder that affects communication and behavior. Most assistive technologies for children with autistic traits have been designed to support single, targeted activity function such as learning and communication. In this paper, we report the design and development of an assistive mobile application with heart rate monitoring to help children with ASD in their daily life activities. The integrated mobile application, App4Autism was developed using a holistic design approach with the aim of enhancing communication, interaction and learning skills while providing emotion regulation support through music listening and heart rate monitoring. A novel focus of App4Autism is on noise sensitivity; to play music upon automatic detection of loud excessive noise (in decibel) while at the same time, monitoring the user’s heart rate using a pulse sensor. The paper focuses on a study to better understand the potential use and incorporation of music listening and heart rate/anxiety level monitoring in the app. The paper provides results of investigation into which music genre is more suitable to keep users calm. Initial experiment involved a general population sample; with results showing that personal music preference might have calming effects on users in environments with excessive background noise. We further expand on the design guidelines for creating an integrated assistive technology. © Springer Nature Switzerland AG 2019.}, note = {cited By 0}, keywords = {Assistive Technology, Autism, Diseases, Early Childhoods, Heart, Heart Rate Monitoring, Mobile Applications, Mobile Computing, Patient Monitoring}, pubstate = {published}, tppubtype = {article} } Autism Spectrum Disorder (ASD) is a neurological development disorder that affects communication and behavior. Most assistive technologies for children with autistic traits have been designed to support single, targeted activity function such as learning and communication. In this paper, we report the design and development of an assistive mobile application with heart rate monitoring to help children with ASD in their daily life activities. The integrated mobile application, App4Autism was developed using a holistic design approach with the aim of enhancing communication, interaction and learning skills while providing emotion regulation support through music listening and heart rate monitoring. A novel focus of App4Autism is on noise sensitivity; to play music upon automatic detection of loud excessive noise (in decibel) while at the same time, monitoring the user’s heart rate using a pulse sensor. The paper focuses on a study to better understand the potential use and incorporation of music listening and heart rate/anxiety level monitoring in the app. The paper provides results of investigation into which music genre is more suitable to keep users calm. Initial experiment involved a general population sample; with results showing that personal music preference might have calming effects on users in environments with excessive background noise. We further expand on the design guidelines for creating an integrated assistive technology. © Springer Nature Switzerland AG 2019. |
Zamin, N; Norwawi, N M; Arshad, N I; Ismail, M A A Jawi alphabot: A jawi teaching robot for children with autism Journal Article International Journal of Advanced Trends in Computer Science and Engineering, 8 (1.4 S1), pp. 363-367, 2019, ISSN: 22783091, (cited By 1). Abstract | Links | BibTeX | Tags: @article{Zamin2019363, title = {Jawi alphabot: A jawi teaching robot for children with autism}, author = {N Zamin and N M Norwawi and N I Arshad and M A A Ismail}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074511817&doi=10.30534%2fijatcse%2f2019%2f5581.42019&partnerID=40&md5=d0ade3f7301cd921044cd9d4a9955cfc}, doi = {10.30534/ijatcse/2019/5581.42019}, issn = {22783091}, year = {2019}, date = {2019-01-01}, journal = {International Journal of Advanced Trends in Computer Science and Engineering}, volume = {8}, number = {1.4 S1}, pages = {363-367}, publisher = {World Academy of Research in Science and Engineering}, abstract = {The children who have disability in their social interaction and communication are categorized as children with autism. Often autistic children are facing challenges in independent living causing many concerns toward teaching and learning for the autistic children. As a result, therapists and educators of autistic children are facing distress when teaching the autistic children as it is harder to retain their attention during the learning process. Hence, there are some researchers suggest robotic approach as clinical tool to assist therapist especially teachers in teaching session with autistic children. Therefore, this research is focusing on developing a robot to teach the basic Jawi modules to the autistic children. The objective of this paper is twofold, presenting: (1) the ways Jawi Alphabot is programmed to perform teaching, and 2) the attentive assessment results that shows the effectiveness of robotics intervention in learning Jawi among the autistics. Besides, a module for the teacher and the children is also available as a guideline for them to implement this robotic learning process. During the experimental design testing, the autistic children are divided into two groups (i.e. control group and experimental group) and were given different intervention in learning Jawi. The intervention in learning Jawi are: 1) traditional method and 2) robotics intervention method. The results are discussed with evidences that highlights how robotics intervention could alleviate attentiveness in learning among the autistic children. © 2019, World Academy of Research in Science and Engineering. All rights reserved.}, note = {cited By 1}, keywords = {}, pubstate = {published}, tppubtype = {article} } The children who have disability in their social interaction and communication are categorized as children with autism. Often autistic children are facing challenges in independent living causing many concerns toward teaching and learning for the autistic children. As a result, therapists and educators of autistic children are facing distress when teaching the autistic children as it is harder to retain their attention during the learning process. Hence, there are some researchers suggest robotic approach as clinical tool to assist therapist especially teachers in teaching session with autistic children. Therefore, this research is focusing on developing a robot to teach the basic Jawi modules to the autistic children. The objective of this paper is twofold, presenting: (1) the ways Jawi Alphabot is programmed to perform teaching, and 2) the attentive assessment results that shows the effectiveness of robotics intervention in learning Jawi among the autistics. Besides, a module for the teacher and the children is also available as a guideline for them to implement this robotic learning process. During the experimental design testing, the autistic children are divided into two groups (i.e. control group and experimental group) and were given different intervention in learning Jawi. The intervention in learning Jawi are: 1) traditional method and 2) robotics intervention method. The results are discussed with evidences that highlights how robotics intervention could alleviate attentiveness in learning among the autistic children. © 2019, World Academy of Research in Science and Engineering. All rights reserved. |
Nor, N K; Ghozali, A H; Ismail, J Prevalence of overweight and obesity among children and adolescents with autism spectrum disorder and associated risk factors Journal Article Frontiers in Pediatrics, 7 (FEB), 2019, ISSN: 22962360, (cited By 5). Abstract | Links | BibTeX | Tags: Adolescent, Adult, Article, Autism, Body Mass, Brief Autism Mealtime Beahavior Questionnaire, Child Development, Childhood Obesity, Children, Children Sleep Habits Questionnaire, Controlled Study, Cross-Sectional Study, Feeding Difficulty, Female, Food Refusal, Human, Major Clinical Study, Malaysian, Male, Mother, Paternal Age, Physical Activity, Physical Activity for Older Children Questionnaire, Prevalence, Questionnaires, Risk Factor, Sleep Disorder, Underweight @article{Nor2019, title = {Prevalence of overweight and obesity among children and adolescents with autism spectrum disorder and associated risk factors}, author = {N K Nor and A H Ghozali and J Ismail}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064414280&doi=10.3389%2ffped.2019.00038&partnerID=40&md5=4bb61b1df043a4adf79618e223d77f26}, doi = {10.3389/fped.2019.00038}, issn = {22962360}, year = {2019}, date = {2019-01-01}, journal = {Frontiers in Pediatrics}, volume = {7}, number = {FEB}, publisher = {Frontiers Media S.A.}, abstract = {Introduction: Prevalence of obesity in Autism Spectrum Disorder (ASD) has been reported to be higher than in the general population. Determining prevalence may help increase awareness of obesity in ASD and potentially lead to initiatives to reduce obesity. In order to understand obesity in ASD children, common risk factors were assessed including physical activity, feeding problems and sleep disturbances. Methods: This is a cross-sectional study performed at the Child Development Center at Universiti Kebangsaan Malaysia Medical Center on 151 ASD children aged 2-18 years. Anthropometric and demographic information were obtained and parents completed three questionnaires; Children Sleep Habits Questionnaire (CSHQ), Physical Activity for Older Children Questionnaire (PAQ-C) and Brief Autism Mealtime Behavior Questionnaire (BAMBI). Results: For ASD children in our sample, the prevalence of overweight (BMI ≥85th to < 95th percentiles) was 11.3% and the prevalence of obesity (BMI ≥95th percentile) was 21.9%. The overweight/obese ASD children's median age was higher at 8.5 years (IQR 5.81-10.13) compared to the normal/underweight group of 6.33 years (IQR 4.75-7.7) with a p-value of 0.001. The two groups also differed significantly for maternal BMI and paternal age. The median maternal BMI in the overweight/obese group was 26.05 (IQR 23.35-32.25), statistically significantly higher (p = 0.003) than in the non-overweight/obese group, 24.7 (IQR 21-27.9). The median paternal age of 40 years (IQR 37-44) was statistically significantly higher (p = 0.039) in the overweight/obese group, compared to the median paternal age in the non-overweight/obese group of 38 (IQR 35-42). The male overweight/obese children had median PAQ-C score of 2.44 (IQR 2.00-3.00) vs. 2.89 (IQR 2.35-3.53) in the counterpart group with a p-value of 0.01. Using the multiple linear regression stepwise method, three predictors associated with BMI percentiles reached a statistical level of significance; PAQ-C score in males (p < 0.001), the BAMBI domains of Food Refusal (p = 0.001) and Limited Variety of Food (p = 0.001). Conclusions: The prevalence of obesity and overweight is high among Malaysian ASD children and adolescents. Older child age, high maternal BMI, older paternal age, low physical activity, low likelihood of food refusal and high likelihood of food selectivity were found to be risk factors for high BMI in these children. © 2019 Kamal Nor, Ghozali and Ismail.}, note = {cited By 5}, keywords = {Adolescent, Adult, Article, Autism, Body Mass, Brief Autism Mealtime Beahavior Questionnaire, Child Development, Childhood Obesity, Children, Children Sleep Habits Questionnaire, Controlled Study, Cross-Sectional Study, Feeding Difficulty, Female, Food Refusal, Human, Major Clinical Study, Malaysian, Male, Mother, Paternal Age, Physical Activity, Physical Activity for Older Children Questionnaire, Prevalence, Questionnaires, Risk Factor, Sleep Disorder, Underweight}, pubstate = {published}, tppubtype = {article} } Introduction: Prevalence of obesity in Autism Spectrum Disorder (ASD) has been reported to be higher than in the general population. Determining prevalence may help increase awareness of obesity in ASD and potentially lead to initiatives to reduce obesity. In order to understand obesity in ASD children, common risk factors were assessed including physical activity, feeding problems and sleep disturbances. Methods: This is a cross-sectional study performed at the Child Development Center at Universiti Kebangsaan Malaysia Medical Center on 151 ASD children aged 2-18 years. Anthropometric and demographic information were obtained and parents completed three questionnaires; Children Sleep Habits Questionnaire (CSHQ), Physical Activity for Older Children Questionnaire (PAQ-C) and Brief Autism Mealtime Behavior Questionnaire (BAMBI). Results: For ASD children in our sample, the prevalence of overweight (BMI ≥85th to < 95th percentiles) was 11.3% and the prevalence of obesity (BMI ≥95th percentile) was 21.9%. The overweight/obese ASD children's median age was higher at 8.5 years (IQR 5.81-10.13) compared to the normal/underweight group of 6.33 years (IQR 4.75-7.7) with a p-value of 0.001. The two groups also differed significantly for maternal BMI and paternal age. The median maternal BMI in the overweight/obese group was 26.05 (IQR 23.35-32.25), statistically significantly higher (p = 0.003) than in the non-overweight/obese group, 24.7 (IQR 21-27.9). The median paternal age of 40 years (IQR 37-44) was statistically significantly higher (p = 0.039) in the overweight/obese group, compared to the median paternal age in the non-overweight/obese group of 38 (IQR 35-42). The male overweight/obese children had median PAQ-C score of 2.44 (IQR 2.00-3.00) vs. 2.89 (IQR 2.35-3.53) in the counterpart group with a p-value of 0.01. Using the multiple linear regression stepwise method, three predictors associated with BMI percentiles reached a statistical level of significance; PAQ-C score in males (p < 0.001), the BAMBI domains of Food Refusal (p = 0.001) and Limited Variety of Food (p = 0.001). Conclusions: The prevalence of obesity and overweight is high among Malaysian ASD children and adolescents. Older child age, high maternal BMI, older paternal age, low physical activity, low likelihood of food refusal and high likelihood of food selectivity were found to be risk factors for high BMI in these children. © 2019 Kamal Nor, Ghozali and Ismail. |
Khan, N A; Soopramanien, M; Siddiqui, R Crocodiles and alligators: Physicians’ answer to cancer? Journal Article Current Oncology, 26 (3), pp. 186, 2019, ISSN: 11980052, (cited By 1). Links | BibTeX | Tags: Allergic Disease, Alligators and Crocodiles, Animal Product, Animals, Antineoplastic Activity, Antineoplastic Agent, Article, Atopic Dermatitis, Autism, Cancer Growth, Cancer Therapy, Carcinogen, Contaminated Organism, Crocodilian, End Cretaceous Mass Extinction, Environmental Factor, Environmental Stress, Gastrointestinal Microbiome, Health Behaviour, Heavy Metal, Human, Immune System, Inflammatory Bowel Disease, Intestine Flora, Longevity, Metabolic Disorder, Microbiology, Neoplasm, Neoplasms, Nerve Cell Differentiation, Physician, Schizophrenia, Survival Analysis, Terminal Disease @article{Khan2019186, title = {Crocodiles and alligators: Physicians’ answer to cancer?}, author = {N A Khan and M Soopramanien and R Siddiqui}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069313377&doi=10.3747%2fco.26.4855&partnerID=40&md5=6a266208d5fe14a1c888bb1db397d744}, doi = {10.3747/co.26.4855}, issn = {11980052}, year = {2019}, date = {2019-01-01}, journal = {Current Oncology}, volume = {26}, number = {3}, pages = {186}, publisher = {Multimed Inc.}, note = {cited By 1}, keywords = {Allergic Disease, Alligators and Crocodiles, Animal Product, Animals, Antineoplastic Activity, Antineoplastic Agent, Article, Atopic Dermatitis, Autism, Cancer Growth, Cancer Therapy, Carcinogen, Contaminated Organism, Crocodilian, End Cretaceous Mass Extinction, Environmental Factor, Environmental Stress, Gastrointestinal Microbiome, Health Behaviour, Heavy Metal, Human, Immune System, Inflammatory Bowel Disease, Intestine Flora, Longevity, Metabolic Disorder, Microbiology, Neoplasm, Neoplasms, Nerve Cell Differentiation, Physician, Schizophrenia, Survival Analysis, Terminal Disease}, pubstate = {published}, tppubtype = {article} } |
Khowaja, K; Salim, S S; Asemi, A; Ghulamani, S; Shah, A Universal Access in the Information Society, 2019, ISSN: 16155289, (cited By 2). Abstract | Links | BibTeX | Tags: Augmented Reality, Autism Spectrum Disorders, Children with Autism, Computer Aided Instruction, Decoding, Diseases, Language Comprehensions, Maintenance, Mammals, Multi-Modal Interfaces, Post Interventions, Reading Comprehension, Serious Games, Spectrum Analysis, Transfer Information, Virtual Learning Environments, Virtual Reality @article{Khowaja2019c, title = {A systematic review of modalities in computer-based interventions (CBIs) for language comprehension and decoding skills of children with autism spectrum disorder (ASD)}, author = {K Khowaja and S S Salim and A Asemi and S Ghulamani and A Shah}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062722488&doi=10.1007%2fs10209-019-00646-1&partnerID=40&md5=7ff6d03104bfe1e04f6b069b265f671a}, doi = {10.1007/s10209-019-00646-1}, issn = {16155289}, year = {2019}, date = {2019-01-01}, journal = {Universal Access in the Information Society}, publisher = {Springer Verlag}, abstract = {This paper presents a systematic review of the literature on the modalities used in computer-based interventions (CBIs) and the impact of using these interventions in the learning, generalisation, and maintenance of language comprehension and decoding skills for children with autism spectrum disorder (ASD), ending with an appraisal of the certainty of evidence. Despite the importance of both skills in the reading comprehension and overall learning, a limited number of studies have been found. These include seven studies on language comprehension and seven studies on decoding. The shortlisted studies were analysed and a very limited number of modalities were found to have been used; text, graphics, audio, video, and mouse movement are used in all the studies and are termed basic modalities. Statistical analysis was also conducted on three parameters: (1) outcome of the study; (2) generalisation; and (3) maintenance. The analysis showed that CBIs were effective in facilitating these children’s learning; there was a significant improvement in the performance of children from the baseline to during and the post-intervention period. The analysis of generalisation has revealed positive results, indicating that the children were able to transfer information to a different setting or situation. Positive results are also noted from the analysis of maintenance, which indicate that the children retained information following the withdrawal of intervention. The combination of teachers’ instructions and CBI has provided better results than using either of them separately. This study has discovered 23 potential modalities and 2 potential CBIs including serious games and virtual learning environments that can be explored for language comprehension and decoding skills. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.}, note = {cited By 2}, keywords = {Augmented Reality, Autism Spectrum Disorders, Children with Autism, Computer Aided Instruction, Decoding, Diseases, Language Comprehensions, Maintenance, Mammals, Multi-Modal Interfaces, Post Interventions, Reading Comprehension, Serious Games, Spectrum Analysis, Transfer Information, Virtual Learning Environments, Virtual Reality}, pubstate = {published}, tppubtype = {article} } This paper presents a systematic review of the literature on the modalities used in computer-based interventions (CBIs) and the impact of using these interventions in the learning, generalisation, and maintenance of language comprehension and decoding skills for children with autism spectrum disorder (ASD), ending with an appraisal of the certainty of evidence. Despite the importance of both skills in the reading comprehension and overall learning, a limited number of studies have been found. These include seven studies on language comprehension and seven studies on decoding. The shortlisted studies were analysed and a very limited number of modalities were found to have been used; text, graphics, audio, video, and mouse movement are used in all the studies and are termed basic modalities. Statistical analysis was also conducted on three parameters: (1) outcome of the study; (2) generalisation; and (3) maintenance. The analysis showed that CBIs were effective in facilitating these children’s learning; there was a significant improvement in the performance of children from the baseline to during and the post-intervention period. The analysis of generalisation has revealed positive results, indicating that the children were able to transfer information to a different setting or situation. Positive results are also noted from the analysis of maintenance, which indicate that the children retained information following the withdrawal of intervention. The combination of teachers’ instructions and CBI has provided better results than using either of them separately. This study has discovered 23 potential modalities and 2 potential CBIs including serious games and virtual learning environments that can be explored for language comprehension and decoding skills. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature. |
Khowaja, K; Salim, S S Universal Access in the Information Society, 2019, ISSN: 16155289, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Khowaja2019d, title = {Correction to: A framework to design vocabulary-based serious games for children with autism spectrum disorder (ASD) (Universal Access in the Information Society, (2019), 10.1007/s10209-019-00689-4)}, author = {K Khowaja and S S Salim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074941681&doi=10.1007%2fs10209-019-00699-2&partnerID=40&md5=f7c060a2b55f381087426353c39fd28c}, doi = {10.1007/s10209-019-00699-2}, issn = {16155289}, year = {2019}, date = {2019-01-01}, journal = {Universal Access in the Information Society}, publisher = {Springer Verlag}, abstract = {In the original article, the acknowledgement section is missing. The funding information is given below:. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } In the original article, the acknowledgement section is missing. The funding information is given below:. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature. |
Pramudya, G; Amran, A C; Suyanto, M; Ruslan, S N A; Noor, H A M; Abas, Z A Assessing assistive learning technologies with experimental design Journal Article International Journal of Advanced Computer Science and Applications, 10 (7), pp. 504-508, 2019, ISSN: 2158107X, (cited By 0). Abstract | Links | BibTeX | Tags: @article{Pramudya2019504, title = {Assessing assistive learning technologies with experimental design}, author = {G Pramudya and A C Amran and M Suyanto and S N A Ruslan and H A M Noor and Z A Abas}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85070057993&partnerID=40&md5=e57864bfaef55cc115526596c77b0de7}, issn = {2158107X}, year = {2019}, date = {2019-01-01}, journal = {International Journal of Advanced Computer Science and Applications}, volume = {10}, number = {7}, pages = {504-508}, publisher = {Science and Information Organization}, abstract = {Assistive learning technologies are generally computer-based instruments which are focused at supporting individuals with disabilities in enhancing their learning session with minimal intervention of parents, guardians, as well as helpers. Assessments using experimental research design have frequently been utilized in order to evaluate their efficacy along with feasibility. An experimental design is categorized by experimental units or treatment to use, the tendencies that are tested, as well as the way treatments are designated to units. The experimental or treatment units need sufficient a number of and representative respondents or sample. Even so, due to the limited numbers of sample units or respondents, such type of experiments is noted as subtle yet challenging experiences. Based upon our substantial encounters, this article tries to disclose such precious research experiences. © 2018 The Science and Information (SAI) Organization Limited.}, note = {cited By 0}, keywords = {}, pubstate = {published}, tppubtype = {article} } Assistive learning technologies are generally computer-based instruments which are focused at supporting individuals with disabilities in enhancing their learning session with minimal intervention of parents, guardians, as well as helpers. Assessments using experimental research design have frequently been utilized in order to evaluate their efficacy along with feasibility. An experimental design is categorized by experimental units or treatment to use, the tendencies that are tested, as well as the way treatments are designated to units. The experimental or treatment units need sufficient a number of and representative respondents or sample. Even so, due to the limited numbers of sample units or respondents, such type of experiments is noted as subtle yet challenging experiences. Based upon our substantial encounters, this article tries to disclose such precious research experiences. © 2018 The Science and Information (SAI) Organization Limited. |
Saleh, M A; Marbukhari, N; Hashim, H A deep learning approach in robot-assisted behavioral therapy for autistic children Journal Article International Journal of Advanced Trends in Computer Science and Engineering, 8 (1.6 Special Issue), pp. 437-443, 2019, ISSN: 22783091, (cited By 2). Abstract | Links | BibTeX | Tags: @article{Saleh2019437, title = {A deep learning approach in robot-assisted behavioral therapy for autistic children}, author = {M A Saleh and N Marbukhari and H Hashim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078254537&doi=10.30534%2fijatcse%2f2019%2f6381.62019&partnerID=40&md5=8148b109ba08890237c6f80bcac77ed0}, doi = {10.30534/ijatcse/2019/6381.62019}, issn = {22783091}, year = {2019}, date = {2019-01-01}, journal = {International Journal of Advanced Trends in Computer Science and Engineering}, volume = {8}, number = {1.6 Special Issue}, pages = {437-443}, publisher = {World Academy of Research in Science and Engineering}, abstract = {A significant percentage of the world's children are being diagnosed with Autism Spectrum Disorders (ASD every day. According to the most recent reports for Disease Control Data (DCD), ASD affects one in 68 children in the US only. It has been recognized as a neurological disorder characterized by difficulties in social communication and social interaction; abnormal body posturing; repetitive movements and self-abusive behavior. There is no cure for ASD but efforts to mitigate difficulties in social functioning, learning, and to improve quality of life of persons with ASD is usually through behavioral therapy. Robot-assisted behavioral therapy is one emerging field that provides intervention mainly for children with ASD, so far, only to augment traditional rehabilitation approaches. In this approach, robots have been used for different purposes such as for behavior eliciting, rehearsing skills, and improving interaction and socialization skills. Nonetheless, there are still a lot to be done in developing robots that can effectively work towards improving social and emotional confidence in children with ASD. This paper sheds light on recent studies that utilize deep learning technique and sets out to propose a deep learning-based emotion detection system for humanoid robots to enhance robot awareness during therapy sessions. We present a model of the emotion-aware robot-assisted therapy which is expected to ease the prediction and recognition for the emotion and behaviors of autistic children and enhance robot intervention during rehabilitation. It was found that the proposed DL model when tested on an improved trial dataset of normal subjects has increased the accuracy of detection. However, while new deep learning technologies for facial expression recognition algorithms could lead to higher detection accuracy, it is clear from that the size and reliability of the data will be the success factor in this study. © 2019, World Academy of Research in Science and Engineering. All rights reserved.}, note = {cited By 2}, keywords = {}, pubstate = {published}, tppubtype = {article} } A significant percentage of the world's children are being diagnosed with Autism Spectrum Disorders (ASD every day. According to the most recent reports for Disease Control Data (DCD), ASD affects one in 68 children in the US only. It has been recognized as a neurological disorder characterized by difficulties in social communication and social interaction; abnormal body posturing; repetitive movements and self-abusive behavior. There is no cure for ASD but efforts to mitigate difficulties in social functioning, learning, and to improve quality of life of persons with ASD is usually through behavioral therapy. Robot-assisted behavioral therapy is one emerging field that provides intervention mainly for children with ASD, so far, only to augment traditional rehabilitation approaches. In this approach, robots have been used for different purposes such as for behavior eliciting, rehearsing skills, and improving interaction and socialization skills. Nonetheless, there are still a lot to be done in developing robots that can effectively work towards improving social and emotional confidence in children with ASD. This paper sheds light on recent studies that utilize deep learning technique and sets out to propose a deep learning-based emotion detection system for humanoid robots to enhance robot awareness during therapy sessions. We present a model of the emotion-aware robot-assisted therapy which is expected to ease the prediction and recognition for the emotion and behaviors of autistic children and enhance robot intervention during rehabilitation. It was found that the proposed DL model when tested on an improved trial dataset of normal subjects has increased the accuracy of detection. However, while new deep learning technologies for facial expression recognition algorithms could lead to higher detection accuracy, it is clear from that the size and reliability of the data will be the success factor in this study. © 2019, World Academy of Research in Science and Engineering. All rights reserved. |
Baragash, R S; Al-Samarraie, H; Alzahrani, A I; Alfarraj, O Augmented reality in special education: a meta-analysis of single-subject design studies Journal Article European Journal of Special Needs Education, 2019, ISSN: 08856257, (cited By 2). Abstract | Links | BibTeX | Tags: @article{Baragash2019, title = {Augmented reality in special education: a meta-analysis of single-subject design studies}, author = {R S Baragash and H Al-Samarraie and A I Alzahrani and O Alfarraj}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076892444&doi=10.1080%2f08856257.2019.1703548&partnerID=40&md5=29c2963d145254b1db0fa51e95807ae8}, doi = {10.1080/08856257.2019.1703548}, issn = {08856257}, year = {2019}, date = {2019-01-01}, journal = {European Journal of Special Needs Education}, publisher = {Routledge}, abstract = {There is a growing interest in using augmented reality (AR) applications to support individuals with special needs, such as intellectual disabilities, autism spectrum disorder, attention deficit hyperactivity disorder, and physical disabilities. The purpose of this study is to further examine the effectiveness of AR applications in improving the learning and skill acquisition of individuals with special needs. Following the PRISMA guidelines, a meta-analysis of the overall effectiveness of AR on individuals with different disabilities in single-subject studies was conducted. Sixteen single-subject studies on a more restricted subset of special educational needs types that matched the eligibility criteria were considered to explore the effect of AR on the acquisition of four types of skills: (a) social, (b) living, (c) learning, and (4) physical. The results showed that the AR applications had a large effect across the 16 single-subject studies. The effect of AR was the largest in promoting an individual’s learning skills, followed by social skills, physical skills, and living skills. This study offers an important insight into the relative success of AR in promoting academic and functional living skills to individuals with special needs. It also offers research-based guidance to decision-makers for supporting adolescents with special needs, such as autism spectrum disorders and intellectual disabilities. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.}, note = {cited By 2}, keywords = {}, pubstate = {published}, tppubtype = {article} } There is a growing interest in using augmented reality (AR) applications to support individuals with special needs, such as intellectual disabilities, autism spectrum disorder, attention deficit hyperactivity disorder, and physical disabilities. The purpose of this study is to further examine the effectiveness of AR applications in improving the learning and skill acquisition of individuals with special needs. Following the PRISMA guidelines, a meta-analysis of the overall effectiveness of AR on individuals with different disabilities in single-subject studies was conducted. Sixteen single-subject studies on a more restricted subset of special educational needs types that matched the eligibility criteria were considered to explore the effect of AR on the acquisition of four types of skills: (a) social, (b) living, (c) learning, and (4) physical. The results showed that the AR applications had a large effect across the 16 single-subject studies. The effect of AR was the largest in promoting an individual’s learning skills, followed by social skills, physical skills, and living skills. This study offers an important insight into the relative success of AR in promoting academic and functional living skills to individuals with special needs. It also offers research-based guidance to decision-makers for supporting adolescents with special needs, such as autism spectrum disorders and intellectual disabilities. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. |
Lee, Learn-Han; Ser, Hooi-Leng; Khan, Tahir Mehmood; Gan, Kok-Gan; Goh, Bey-Hing; Mutalib, Nurul-Syakima Ab IDDF2019-ABS-0321 Relationship between autism and gut microbiome: current status and update Journal Article Gut, 68 (Suppl 1), pp. A40–A41, 2019, ISSN: 0017-5749. Abstract | Links | BibTeX | Tags: @article{LeeA40, title = {IDDF2019-ABS-0321 Relationship between autism and gut microbiome: current status and update}, author = {Learn-Han Lee and Hooi-Leng Ser and Tahir Mehmood Khan and Kok-Gan Gan and Bey-Hing Goh and Nurul-Syakima Ab Mutalib}, doi = {10.1136/gutjnl-2019-IDDFAbstracts.76}, issn = {0017-5749}, year = {2019}, date = {2019-01-01}, journal = {Gut}, volume = {68}, number = {Suppl 1}, pages = {A40--A41}, publisher = {BMJ Publishing Group}, abstract = {Background Recently, many reports indicated the role of the gut microbiome in the development of autism in young children. Microbes are capable of synthesizing small molecules like fatty acids and sugars which act as signalling molecules to activate/deactivate nervous system or even trigger an inflammatory response. Thus, the current review aims to explore the role of microbes in the development of autism, summarizing data from animal models and human studies.Methods Referring to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, searches were performed in three databases (PubMed, ScienceDirect, Web of knowledge and; database inception to 31/12/2018) using textquoteleftmicrobiometextquoteright OR textquoteleftmicrobiotatextquoteright combined with textquoteleftautismtextquoteright as MeSH terms. All the titles and Abstracts retrieved were screened based on the inclusion and exclusion criteria. Studies reporting gut microbiome data in relation to the development of autism were included. Studies without gut microbiome data and/or reports on the evaluation on autism were excluded, along with reviews, conference Abstracts, case studies, and comments.Results Out of the 2237 articles were accessed, seven studies were eligible for the qualitative analysis according to the inclusion criteria. Two studies described the murine model of autism, while the remaining five studies focused on children. One study revealed that there are no significant differences in gut microbiome among the three groups--severe, mild and healthy children, while three studies indicated that there is a higher abundance of Proteobacteria and Bacteroides in autistic children, with a reduced population of Firmicutes and Actinobacteria (figure 1). One study highlighted that higher Clostridiaceae species present in autistic children which explain for the development of autism in children as these species could produce toxic metabolic products (e.g., phenols, p-cresol, indole derivatives). Similar results were also observed in autistic animal models - there is increase abundance of Bacteroides, Parabacteroides, Sutterella, Dehalobacterium and Oscillospira genera.Abstract IDDF2019-ABS-0321 Figure 1 Three studies indicated that there is higher abundance of proteobacteria and bacteroides in autistic children with reduced population of firmicutes and actinobacteriaConclusions Altogether, these results revealed a positive correlation between dysbiosis and autism. Microbiome alterations may contribute to the development of autism, particularly via the production of toxic bacterial metabolites and alteration in immune function. By keeping the textquotelefthealthytextquoteright gut bacteria in check, these efforts could improve intestinal and mental health, easing and reducing autistic behaviour in children.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Background Recently, many reports indicated the role of the gut microbiome in the development of autism in young children. Microbes are capable of synthesizing small molecules like fatty acids and sugars which act as signalling molecules to activate/deactivate nervous system or even trigger an inflammatory response. Thus, the current review aims to explore the role of microbes in the development of autism, summarizing data from animal models and human studies.Methods Referring to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, searches were performed in three databases (PubMed, ScienceDirect, Web of knowledge and; database inception to 31/12/2018) using textquoteleftmicrobiometextquoteright OR textquoteleftmicrobiotatextquoteright combined with textquoteleftautismtextquoteright as MeSH terms. All the titles and Abstracts retrieved were screened based on the inclusion and exclusion criteria. Studies reporting gut microbiome data in relation to the development of autism were included. Studies without gut microbiome data and/or reports on the evaluation on autism were excluded, along with reviews, conference Abstracts, case studies, and comments.Results Out of the 2237 articles were accessed, seven studies were eligible for the qualitative analysis according to the inclusion criteria. Two studies described the murine model of autism, while the remaining five studies focused on children. One study revealed that there are no significant differences in gut microbiome among the three groups--severe, mild and healthy children, while three studies indicated that there is a higher abundance of Proteobacteria and Bacteroides in autistic children, with a reduced population of Firmicutes and Actinobacteria (figure 1). One study highlighted that higher Clostridiaceae species present in autistic children which explain for the development of autism in children as these species could produce toxic metabolic products (e.g., phenols, p-cresol, indole derivatives). Similar results were also observed in autistic animal models - there is increase abundance of Bacteroides, Parabacteroides, Sutterella, Dehalobacterium and Oscillospira genera.Abstract IDDF2019-ABS-0321 Figure 1 Three studies indicated that there is higher abundance of proteobacteria and bacteroides in autistic children with reduced population of firmicutes and actinobacteriaConclusions Altogether, these results revealed a positive correlation between dysbiosis and autism. Microbiome alterations may contribute to the development of autism, particularly via the production of toxic bacterial metabolites and alteration in immune function. By keeping the textquotelefthealthytextquoteright gut bacteria in check, these efforts could improve intestinal and mental health, easing and reducing autistic behaviour in children. |
Hamzaid, Nur Hana Binti; Haron, Hasnah; Ismail, Haziqah Acceptance of High-Fiber Cookies among Children with Autism Spectrum Disorder Journal Article ANNALS OF NUTRITION AND METABOLISM, 75 (3), pp. 165, 2019, ISSN: 0250-6807. BibTeX | Tags: Acceptance, ASD, Autism, High Fiber Cookies @article{ISI:000480262701183, title = {Acceptance of High-Fiber Cookies among Children with Autism Spectrum Disorder}, author = {Nur Hana Binti Hamzaid and Hasnah Haron and Haziqah Ismail}, issn = {0250-6807}, year = {2019}, date = {2019-01-01}, journal = {ANNALS OF NUTRITION AND METABOLISM}, volume = {75}, number = {3}, pages = {165}, publisher = {KARGER}, address = {ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND}, keywords = {Acceptance, ASD, Autism, High Fiber Cookies}, pubstate = {published}, tppubtype = {article} } |
Yi, Lim Heng; Hassan, Ahmad Sanusi; Arab, Yasser; Angood, Rasha Saeed Abdulla Ba LEVELS OF PERMEABILITY AND WAYFINDING IN AUTISM INSTITUTION Journal Article INTERNATIONAL TRANSACTION JOURNAL OF ENGINEERING MANAGEMENT & APPLIED SCIENCES & TECHNOLOGIES, 10 (14, SI), 2019, ISSN: 2228-9860. Abstract | Links | BibTeX | Tags: Justified Graph, Permeability, Space Syntax, Spatial Configuration, Wayfinding Analysis @article{ISI:000488883000001, title = {LEVELS OF PERMEABILITY AND WAYFINDING IN AUTISM INSTITUTION}, author = {Lim Heng Yi and Ahmad Sanusi Hassan and Yasser Arab and Rasha Saeed Abdulla Ba Angood}, doi = {10.14456/ITJEMAST.2019.179}, issn = {2228-9860}, year = {2019}, date = {2019-01-01}, journal = {INTERNATIONAL TRANSACTION JOURNAL OF ENGINEERING MANAGEMENT & APPLIED SCIENCES & TECHNOLOGIES}, volume = {10}, number = {14, SI}, publisher = {TUENGR GROUP}, address = {88-244 MOO 3 KLONG NO 2 KLONG-LUANG, PATHUMTAN, 12120, THAILAND}, abstract = {Autism Institute is an organisation that helps autistic students who need legal and special education with appropriate programs and services. This study is to identify the level of permeability and wayfinding which determines the quality of the building's spatial configuration. This research evaluates the space planning through the floor layout plans which will discover and understand the quality of spatial configuration for Autism Institute. To achieve the research objective, the research study investigates educational and autism institutions with reference to space syntax analysis. The case studies selected for analysis were Flower with Kindergarten in South Korea and Pacific Autism Family Center in Canada. A justified graph and numbering indication system for each case study are conducted, and the resulting graph is compared and summarised based on the level of permeability, wayfinding and spatial configuration in relation to space syntax. (C) 2019 INT TRANS J ENG MANAG SCI TECH.}, keywords = {Justified Graph, Permeability, Space Syntax, Spatial Configuration, Wayfinding Analysis}, pubstate = {published}, tppubtype = {article} } Autism Institute is an organisation that helps autistic students who need legal and special education with appropriate programs and services. This study is to identify the level of permeability and wayfinding which determines the quality of the building's spatial configuration. This research evaluates the space planning through the floor layout plans which will discover and understand the quality of spatial configuration for Autism Institute. To achieve the research objective, the research study investigates educational and autism institutions with reference to space syntax analysis. The case studies selected for analysis were Flower with Kindergarten in South Korea and Pacific Autism Family Center in Canada. A justified graph and numbering indication system for each case study are conducted, and the resulting graph is compared and summarised based on the level of permeability, wayfinding and spatial configuration in relation to space syntax. (C) 2019 INT TRANS J ENG MANAG SCI TECH. |
Yen, Eow Shiang; Ying, GanWan; Ying, Lim Poh; Hamidin, A Association between Nutritional Factors and Severity Among Children with Autism Spectrum Disorder in Malaysia Journal Article ANNALS OF NUTRITION AND METABOLISM, 75 (3), pp. 90, 2019, ISSN: 0250-6807. BibTeX | Tags: Autism Severity, Autism Spectrum Disorders, Children, Nutritional Factors @article{ISI:000480262700252, title = {Association between Nutritional Factors and Severity Among Children with Autism Spectrum Disorder in Malaysia}, author = {Eow Shiang Yen and GanWan Ying and Lim Poh Ying and A Hamidin}, issn = {0250-6807}, year = {2019}, date = {2019-01-01}, journal = {ANNALS OF NUTRITION AND METABOLISM}, volume = {75}, number = {3}, pages = {90}, publisher = {KARGER}, address = {ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND}, keywords = {Autism Severity, Autism Spectrum Disorders, Children, Nutritional Factors}, pubstate = {published}, tppubtype = {article} } |
2018 |
Ghazali, Roslinda; Sakip, Siti Rasidah Md.; Samsuddin, Ismail Preliminary Study on Sensory Design for Autism Centre Journal Article ENVIRONMENT-BEHAVIOUR PROCEEDINGS JOURNAL, 3 (8), pp. 46-54, 2018, ISSN: 2398-4287, (8th Asia Pacific International Conference on Environment-Behaviour Studies (AicE-Bs), Univ Sheffield, Sch Architecture, Sheffield, ENGLAND, JUL 14-15, 2018). Abstract | Links | BibTeX | Tags: Autism, Design Criteria Checklist, physical learning environment, Sensory Design @article{ISI:000454301800006, title = {Preliminary Study on Sensory Design for Autism Centre}, author = {Roslinda Ghazali and Siti Rasidah Md. Sakip and Ismail Samsuddin}, doi = {10.21834/e-bpj.v3i8.1392}, issn = {2398-4287}, year = {2018}, date = {2018-08-01}, journal = {ENVIRONMENT-BEHAVIOUR PROCEEDINGS JOURNAL}, volume = {3}, number = {8}, pages = {46-54}, publisher = {E-IPH LTD UK}, address = {THE LEADMILL, 6 LEADMILL RD, PO BOX STUDIO 7, SHEFFIELD, S1 4SE, ENGLAND}, organization = {Assoc Malaysian Environm Behav Researchers; Asso Behav Researchers Asians; cEBs; FAPS; UiTM}, abstract = {Autism Spectrum Disorders (ASD) is a lifelong handicap that affects the lives and the people around them. Knowing them as a unique person, designated learning environment should consider the sensory issues to overcome their needs. However, designers are lack of awareness in terms of sensory design while designing learning spaces for autistic children. This research objective is to identify the sensory design of physical learning enviroment in the Autism Centre, while the paper aims to develop the Design Criteria Checklist of sensory design for Autism Centre. The result of the study highlighted factors that relating to quality physical learning environment.}, note = {8th Asia Pacific International Conference on Environment-Behaviour Studies (AicE-Bs), Univ Sheffield, Sch Architecture, Sheffield, ENGLAND, JUL 14-15, 2018}, keywords = {Autism, Design Criteria Checklist, physical learning environment, Sensory Design}, pubstate = {published}, tppubtype = {article} } Autism Spectrum Disorders (ASD) is a lifelong handicap that affects the lives and the people around them. Knowing them as a unique person, designated learning environment should consider the sensory issues to overcome their needs. However, designers are lack of awareness in terms of sensory design while designing learning spaces for autistic children. This research objective is to identify the sensory design of physical learning enviroment in the Autism Centre, while the paper aims to develop the Design Criteria Checklist of sensory design for Autism Centre. The result of the study highlighted factors that relating to quality physical learning environment. |
Peng, Chew Fong; Munastiwi, Erni; Abdullah, Ramle; Rosli, Noor Aishah; Isa, Zulkifli Md; Rushdan, A R Level of Mathematics Abilities of Mild Autism Children on the McCarthy Scales of Children's Abilities Journal Article ADVANCED SCIENCE LETTERS, 24 (7), pp. 5275-5279, 2018, ISSN: 1936-6612, (2nd Advances in Social Sciences Research International Conference (ASSRIC), Bandung, INDONESIA, MAY 05-06, 2017). Abstract | Links | BibTeX | Tags: Cognitive Ability, Mathematics Abilities, Mild Autism @article{ISI:000445018400126, title = {Level of Mathematics Abilities of Mild Autism Children on the McCarthy Scales of Children's Abilities}, author = {Chew Fong Peng and Erni Munastiwi and Ramle Abdullah and Noor Aishah Rosli and Zulkifli Md Isa and A R Rushdan}, doi = {10.1166/asl.2018.11717}, issn = {1936-6612}, year = {2018}, date = {2018-07-01}, journal = {ADVANCED SCIENCE LETTERS}, volume = {24}, number = {7}, pages = {5275-5279}, publisher = {AMER SCIENTIFIC PUBLISHERS}, address = {26650 THE OLD RD, STE 208, VALENCIA, CA 91381-0751 USA}, organization = {IPN Educ Grp}, abstract = {The objective of this study is to determine the level of mathematics abilities among mild autism children in Klang Valley, Malaysia. A total of ten autistic children aged 5 to 7 years old were selected as respondents. Purposive sampling was used using McCarthy Scales of Children's Abilities (MSCA) to measure the level of cognitive abilities of the children. This instrument consist of three scales; Verbal, Perceptual-Performance and Quantitative. Overall results shows the level of mathematics abilities of mild autism child is at moderate level. However, result also show that there were a significant difference in Verbal, Perceptual Performance and Quantitative Scales.}, note = {2nd Advances in Social Sciences Research International Conference (ASSRIC), Bandung, INDONESIA, MAY 05-06, 2017}, keywords = {Cognitive Ability, Mathematics Abilities, Mild Autism}, pubstate = {published}, tppubtype = {article} } The objective of this study is to determine the level of mathematics abilities among mild autism children in Klang Valley, Malaysia. A total of ten autistic children aged 5 to 7 years old were selected as respondents. Purposive sampling was used using McCarthy Scales of Children's Abilities (MSCA) to measure the level of cognitive abilities of the children. This instrument consist of three scales; Verbal, Perceptual-Performance and Quantitative. Overall results shows the level of mathematics abilities of mild autism child is at moderate level. However, result also show that there were a significant difference in Verbal, Perceptual Performance and Quantitative Scales. |
Ibrahim, Zuraida; Alias, Maizam A Review on Using Assistive Technology to Enhance Social Skills Competence Among Children with Autism Spectrum Disorder (ASD) Journal Article ADVANCED SCIENCE LETTERS, 24 (6), pp. 4250-4254, 2018, ISSN: 1936-6612, (International Conference on Science, Engineering, Management and Social Sciences (ICSEMSS), Univ Teknologi Malaysia, Johor Bahru, MALAYSIA, OCT 06-08, 2016). Abstract | Links | BibTeX | Tags: Assistive Technology, Autism Spectrum Disorders, Early Intervention, Social Skills Competence @article{ISI:000444996500092, title = {A Review on Using Assistive Technology to Enhance Social Skills Competence Among Children with Autism Spectrum Disorder (ASD)}, author = {Zuraida Ibrahim and Maizam Alias}, doi = {10.1166/asl.2018.11582}, issn = {1936-6612}, year = {2018}, date = {2018-06-01}, journal = {ADVANCED SCIENCE LETTERS}, volume = {24}, number = {6}, pages = {4250-4254}, publisher = {AMER SCIENTIFIC PUBLISHERS}, address = {26650 THE OLD RD, STE 208, VALENCIA, CA 91381-0751 USA}, organization = {Univ Teknologi Malaysia, Int Student Soc; Int Students Ctr; Univ Teknologi Malaysia, Inst Sultan Iskandar}, abstract = {This paper is intended to explore published reports, journals and articles concerning the implementation of Special Education in Malaysia. The literature review targets the Malaysian education system, focusing on students with special education need (SEN); in particular students with Autism Spectrum Disorder (ASD) in an attempt to describe the current state of understanding on current issues and gaps that lies within them. Specifically, the objectives of this review are to (a) identify effective intervention for ASD children, (b) identify appropriate domains for social skills competence, and (c) to make suggestions for future research. A narrative review was conducted on available literature to provide the explanations on existing knowledge related to the Malaysian education system, special education, ASD, teaching and learning approach for ASD children and effective intervention for ASD children. The findings from the narrative review indicate that inadequate social interaction is the main factor contributing to social skills deficit in ASD children in special education. The skills deficit consequently leads to problems with educators, peers, incompetence for independent living and lack of acceptance by society. The majority of literature makes recommendations on the implementation of assistive technology for skills enhancement. Furthermore, social interaction, social communication, social emotional and social behaviour were identified as domains for social skills competence in ASD children. Overall, the finding from the narrative review provides some support for conducting future research on the implementation of assistive technology in early intervention to enhance the teaching and learning process of social skills competence among ASD children.}, note = {International Conference on Science, Engineering, Management and Social Sciences (ICSEMSS), Univ Teknologi Malaysia, Johor Bahru, MALAYSIA, OCT 06-08, 2016}, keywords = {Assistive Technology, Autism Spectrum Disorders, Early Intervention, Social Skills Competence}, pubstate = {published}, tppubtype = {article} } This paper is intended to explore published reports, journals and articles concerning the implementation of Special Education in Malaysia. The literature review targets the Malaysian education system, focusing on students with special education need (SEN); in particular students with Autism Spectrum Disorder (ASD) in an attempt to describe the current state of understanding on current issues and gaps that lies within them. Specifically, the objectives of this review are to (a) identify effective intervention for ASD children, (b) identify appropriate domains for social skills competence, and (c) to make suggestions for future research. A narrative review was conducted on available literature to provide the explanations on existing knowledge related to the Malaysian education system, special education, ASD, teaching and learning approach for ASD children and effective intervention for ASD children. The findings from the narrative review indicate that inadequate social interaction is the main factor contributing to social skills deficit in ASD children in special education. The skills deficit consequently leads to problems with educators, peers, incompetence for independent living and lack of acceptance by society. The majority of literature makes recommendations on the implementation of assistive technology for skills enhancement. Furthermore, social interaction, social communication, social emotional and social behaviour were identified as domains for social skills competence in ASD children. Overall, the finding from the narrative review provides some support for conducting future research on the implementation of assistive technology in early intervention to enhance the teaching and learning process of social skills competence among ASD children. |
Ghazali, Roslinda; Sakip, Siti Rasidah Md; Samsuddin, Ismail A Review of Sensory Design Physical Learning Environment for Autism Centre in Malaysia Journal Article ENVIRONMENT-BEHAVIOUR PROCEEDINGS JOURNAL, 3 (7), pp. 145-151, 2018, ISSN: 2398-4287, (6th AMER International Conference on Quality of Life in the Built and Natural Environment (AicQoL) / Annual Serial Landmark International Conferences on Quality of Life (ASLI QoL), MALAYSIA, MAR 03-04, 2018). Abstract | Links | BibTeX | Tags: Autism, physical learning environment, Sensory Design @article{ISI:000454299900018, title = {A Review of Sensory Design Physical Learning Environment for Autism Centre in Malaysia}, author = {Roslinda Ghazali and Siti Rasidah Md Sakip and Ismail Samsuddin}, url = {https://ebpj.e-iph.co.uk/index.php/EBProceedings/article/view/1262}, doi = {10.21834/e-bpj.v3i7.1262}, issn = {2398-4287}, year = {2018}, date = {2018-03-01}, journal = {ENVIRONMENT-BEHAVIOUR PROCEEDINGS JOURNAL}, volume = {3}, number = {7}, pages = {145-151}, publisher = {E-IPH LTD UK}, address = {THE LEADMILL, 6 LEADMILL RD, PO BOX STUDIO 7, SHEFFIELD, S1 4SE, ENGLAND}, organization = {Assoc Malaysian Environm Behav Researchers; Assoc Behav Researchers Asians; Ctr Environm Behav Studies; Univ Teknologi MARA, Fac Architecture, Planning & Surveying}, abstract = {Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that impairs verbal and non-verbal communication and social interaction by showing themselves in repetitive behaviour, sensory issues, and cognitive delay. With proper learning environment, autistic children can continue their lives with their peers who exhibit regular development. The paper aims to develop a conceptual sensory design of Autism Physical Learning Environment. The objective is to identify sensory issues for design consideration in a physical learning environment. Perhaps, this could help designers to gain better understand the variables of certain school design features and school facilities.}, note = {6th AMER International Conference on Quality of Life in the Built and Natural Environment (AicQoL) / Annual Serial Landmark International Conferences on Quality of Life (ASLI QoL), MALAYSIA, MAR 03-04, 2018}, keywords = {Autism, physical learning environment, Sensory Design}, pubstate = {published}, tppubtype = {article} } Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that impairs verbal and non-verbal communication and social interaction by showing themselves in repetitive behaviour, sensory issues, and cognitive delay. With proper learning environment, autistic children can continue their lives with their peers who exhibit regular development. The paper aims to develop a conceptual sensory design of Autism Physical Learning Environment. The objective is to identify sensory issues for design consideration in a physical learning environment. Perhaps, this could help designers to gain better understand the variables of certain school design features and school facilities. |
Wahdi, Abdul E V F; Dzulkifli, M A The effectiveness of computer-assisted instruction in vocabulary learning Conference Institute of Electrical and Electronics Engineers Inc., 2018, ISBN: 9781538675250, (cited By 0). Abstract | Links | BibTeX | Tags: Autism Spectrum Disorders, Children with Autism, Computer Aided Instruction, Computer Assisted Instruction, Diseases, E-learning, Language, Vocabulary Learning @conference{AbdulWahdi2018219, title = {The effectiveness of computer-assisted instruction in vocabulary learning}, author = {E V F Abdul Wahdi and M A Dzulkifli}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060451986&doi=10.1109%2fICT4M.2018.00048&partnerID=40&md5=81d87b5f8564c0edb66e7ece650154cd}, doi = {10.1109/ICT4M.2018.00048}, isbn = {9781538675250}, year = {2018}, date = {2018-01-01}, journal = {Proceedings - International Conference on Information and Communication Technology for the Muslim World 2018, ICT4M 2018}, pages = {219-226}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {The present study aimed to examine the effectiveness of computer-assisted instruction (CAI) on vocabulary learning for children with Autism Spectrum Disorder (ASD) who are non-native English speakers. A lack of educational strategies may hinder the children from benefitting the most from their education. Previous literature has demonstrated that CAI can be effective in enhancing language development. However, research on the applicability of CAI in the Malaysian context whom majority are non-native English speakers is limited. 29 children with ASD aged four to seven were recruited through purposive sampling from two branches of an autism centre. The present study employed an experimental mixed-design in which the children were assigned to two groups which are CAI and a control group (non-CAI) based on the centre they attended. The CAI group used computer with software program of First Word II while the control group received the conventional teaching instruction. Results of a 2 x 2 mixed ANOVA indicate that there were significant main effects of time (i.e., pre and post intervention) on both participants' receptive and expressive vocabulary learning. Potential explanations of these findings were discussed in this study. Implications, strengths, limitations, and recommendations for future research were also discussed. © 2018 IEEE.}, note = {cited By 0}, keywords = {Autism Spectrum Disorders, Children with Autism, Computer Aided Instruction, Computer Assisted Instruction, Diseases, E-learning, Language, Vocabulary Learning}, pubstate = {published}, tppubtype = {conference} } The present study aimed to examine the effectiveness of computer-assisted instruction (CAI) on vocabulary learning for children with Autism Spectrum Disorder (ASD) who are non-native English speakers. A lack of educational strategies may hinder the children from benefitting the most from their education. Previous literature has demonstrated that CAI can be effective in enhancing language development. However, research on the applicability of CAI in the Malaysian context whom majority are non-native English speakers is limited. 29 children with ASD aged four to seven were recruited through purposive sampling from two branches of an autism centre. The present study employed an experimental mixed-design in which the children were assigned to two groups which are CAI and a control group (non-CAI) based on the centre they attended. The CAI group used computer with software program of First Word II while the control group received the conventional teaching instruction. Results of a 2 x 2 mixed ANOVA indicate that there were significant main effects of time (i.e., pre and post intervention) on both participants' receptive and expressive vocabulary learning. Potential explanations of these findings were discussed in this study. Implications, strengths, limitations, and recommendations for future research were also discussed. © 2018 IEEE. |
Razi, N I M; Rahman, A W A; Kamaruddin, N Neurophysiological analysis of porn addiction to learning disabilities Conference Institute of Electrical and Electronics Engineers Inc., 2018, ISBN: 9781538675250, (cited By 2). Abstract | Links | BibTeX | Tags: Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorders, Diseases, Dyslexia, Electroencephalography, Learning Disorder, Neurophysiological, Neurophysiology, Porn Addiction @conference{Razi2018272, title = {Neurophysiological analysis of porn addiction to learning disabilities}, author = {N I M Razi and A W A Rahman and N Kamaruddin}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060456087&doi=10.1109%2fICT4M.2018.00057&partnerID=40&md5=40b96e377414d3bed38a2803752c165a}, doi = {10.1109/ICT4M.2018.00057}, isbn = {9781538675250}, year = {2018}, date = {2018-01-01}, journal = {Proceedings - International Conference on Information and Communication Technology for the Muslim World 2018, ICT4M 2018}, pages = {272-277}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {Learning disability results from a reduced intellectual ability that can be observed from the lack of listening, speaking, reading, writing, reasoning, or mathematical proficiencies. Such condition may expose the children from the unfiltered porn contents freely available from the Internet as they are unaware or have minimal understanding of the negative effects of the pornographic contents. The exposure to pornographic contents that are unmonitored may result to porn addiction as it may trigger excitement and pleasure induced. Hence, this paper attempts to explore the empirical evidence of the correlation between learning disability and pornography addiction by using the electroencephalogram (EEG) of children from a private psychology clinic. The experimental results show that, there are weak correlation between learning disability based on the EEG frequency bands and porn addiction. It can be hoped that such approach is a stepping step in further exploring the relationship between porn addiction and learning disability. © 2018 IEEE.}, note = {cited By 2}, keywords = {Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorders, Diseases, Dyslexia, Electroencephalography, Learning Disorder, Neurophysiological, Neurophysiology, Porn Addiction}, pubstate = {published}, tppubtype = {conference} } Learning disability results from a reduced intellectual ability that can be observed from the lack of listening, speaking, reading, writing, reasoning, or mathematical proficiencies. Such condition may expose the children from the unfiltered porn contents freely available from the Internet as they are unaware or have minimal understanding of the negative effects of the pornographic contents. The exposure to pornographic contents that are unmonitored may result to porn addiction as it may trigger excitement and pleasure induced. Hence, this paper attempts to explore the empirical evidence of the correlation between learning disability and pornography addiction by using the electroencephalogram (EEG) of children from a private psychology clinic. The experimental results show that, there are weak correlation between learning disability based on the EEG frequency bands and porn addiction. It can be hoped that such approach is a stepping step in further exploring the relationship between porn addiction and learning disability. © 2018 IEEE. |
Al-Hiyali, M I; Ishak, A J; Harun, H; Ahmad, S A; Sulaiman, Wan W A A review in modification food-intake behavior by brain stimulation: Excess weight cases Journal Article NeuroQuantology, 16 (12), pp. 86-97, 2018, ISSN: 13035150, (cited By 2). Abstract | Links | BibTeX | Tags: Amygdala, Anoxia, Article, Autism, Binge Eating Disorder, Body Mass, Body Weight, Brain Depth Stimulation, Depolarization, Dietary Intake, Drug Craving, Eating Disorder, Electric Current, Electroencephalogram, Electroencephalography, Energy Consumption, Energy Expenditure, Feeding Behavior, Food Intake, Functional Magnetic Resonance Imaging, Gender, Health Status, Homeostasis, Human, Hunger, Lifestyle, Nerve Cell Membrane Steady Potential, Nerve Excitability, Neurofeedback, Neuromodulation, Nutritional Assessment, Outcome Assessment, Questionnaires, Repetitive Transcranial Magnetic Stimulation, Signal Processing, Training, Transcranial Direct Current Stimulation, Transcranial Magnetic Stimulation, Underweight @article{Al-Hiyali201886, title = {A review in modification food-intake behavior by brain stimulation: Excess weight cases}, author = {M I Al-Hiyali and A J Ishak and H Harun and S A Ahmad and W A Wan Sulaiman}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062843670&doi=10.14704%2fnq.2018.16.12.1894&partnerID=40&md5=235f66cef05a144be23472641f70bd1d}, doi = {10.14704/nq.2018.16.12.1894}, issn = {13035150}, year = {2018}, date = {2018-01-01}, journal = {NeuroQuantology}, volume = {16}, number = {12}, pages = {86-97}, publisher = {Anka Publishers}, abstract = {Obesity and overweight are frequently prescribed for dysfunction in food-intake behavior. Due to the widely prevalence of obesity in last year’s, there is demand for more studies which are aimed to modify the food-intake behavior. For the past decades many researches has applied in modify food-intake by brain training or stimulation. This review for neuroscience studies in modifying food-intake behavior, it’s involved three sections; The first section explained the role of brain activity in food-intake regulation, general ideas about biomedical devices in food-intake behavior are discussed in second section and third section focused on brain-stimulation systems. Finally, this paper concluded with main points that need to be taken into account when designing experimental study for modification food-intake behavior by brain stimulation according to previous studies recommendation and challenges. © 2018, Anka Publishers. All Rights Reserved.}, note = {cited By 2}, keywords = {Amygdala, Anoxia, Article, Autism, Binge Eating Disorder, Body Mass, Body Weight, Brain Depth Stimulation, Depolarization, Dietary Intake, Drug Craving, Eating Disorder, Electric Current, Electroencephalogram, Electroencephalography, Energy Consumption, Energy Expenditure, Feeding Behavior, Food Intake, Functional Magnetic Resonance Imaging, Gender, Health Status, Homeostasis, Human, Hunger, Lifestyle, Nerve Cell Membrane Steady Potential, Nerve Excitability, Neurofeedback, Neuromodulation, Nutritional Assessment, Outcome Assessment, Questionnaires, Repetitive Transcranial Magnetic Stimulation, Signal Processing, Training, Transcranial Direct Current Stimulation, Transcranial Magnetic Stimulation, Underweight}, pubstate = {published}, tppubtype = {article} } Obesity and overweight are frequently prescribed for dysfunction in food-intake behavior. Due to the widely prevalence of obesity in last year’s, there is demand for more studies which are aimed to modify the food-intake behavior. For the past decades many researches has applied in modify food-intake by brain training or stimulation. This review for neuroscience studies in modifying food-intake behavior, it’s involved three sections; The first section explained the role of brain activity in food-intake regulation, general ideas about biomedical devices in food-intake behavior are discussed in second section and third section focused on brain-stimulation systems. Finally, this paper concluded with main points that need to be taken into account when designing experimental study for modification food-intake behavior by brain stimulation according to previous studies recommendation and challenges. © 2018, Anka Publishers. All Rights Reserved. |
Tsuchida, N; Hamada, K; Shiina, M; Kato, M; Kobayashi, Y; Tohyama, J; Kimura, K; Hoshino, K; Ganesan, V; Teik, K W; Nakashima, M; Mitsuhashi, S; Mizuguchi, T; Takata, A; Miyake, N; Saitsu, H; Ogata, K; Miyatake, S; Matsumoto, N GRIN2D variants in three cases of developmental and epileptic encephalopathy Journal Article Clinical Genetics, 94 (6), pp. 538-547, 2018, ISSN: 00099163, (cited By 4). Abstract | Links | BibTeX | Tags: Adolescent, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Article, Atonic Seizure, Attention Deficit Disorder, Autism, Binding Affinity, Brain, Brain Atrophy, Carbamazepine, Case Report, Channel Gating, Chemistry, Children, Clinical Article, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Developmental Delay, Developmental Disorders, Electroencephalogram, Electroencephalography, Epilepsy, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Female, Frontal Lobe Epilepsy, Gene, Gene Frequency, Genetic Variation, Genetics, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Human, Human Cell, Hydrogen Bond, Intellectual Impairment, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Male, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Preschool, Preschool Child, Priority Journal, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, School Child, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing @article{Tsuchida2018538, title = {GRIN2D variants in three cases of developmental and epileptic encephalopathy}, author = {N Tsuchida and K Hamada and M Shiina and M Kato and Y Kobayashi and J Tohyama and K Kimura and K Hoshino and V Ganesan and K W Teik and M Nakashima and S Mitsuhashi and T Mizuguchi and A Takata and N Miyake and H Saitsu and K Ogata and S Miyatake and N Matsumoto}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056487337&doi=10.1111%2fcge.13454&partnerID=40&md5=f0d32670db57261820bc244943cffd62}, doi = {10.1111/cge.13454}, issn = {00099163}, year = {2018}, date = {2018-01-01}, journal = {Clinical Genetics}, volume = {94}, number = {6}, pages = {538-547}, publisher = {Blackwell Publishing Ltd}, abstract = {N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Recently, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. In this study, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd}, note = {cited By 4}, keywords = {Adolescent, Allele, Amino Acid Sequence, Amino Acid Substitution, Amino Terminal Sequence, Anemia, Antibiotic Agent, Antibiotic Therapy, Article, Atonic Seizure, Attention Deficit Disorder, Autism, Binding Affinity, Brain, Brain Atrophy, Carbamazepine, Case Report, Channel Gating, Chemistry, Children, Clinical Article, Clinical Feature, Clobazam, Clonazepam, Conformational Transition, Continuous Infusion, Contracture, Crystal Structure, Cysteine Ethyl Ester Tc 99m, Developmental Delay, Developmental Disorders, Electroencephalogram, Electroencephalography, Epilepsy, Epileptic Discharge, Ethosuximide, Eye Tracking, Febrile Convulsion, Female, Frontal Lobe Epilepsy, Gene, Gene Frequency, Genetic Variation, Genetics, Genotype, GRIN2D Protein, Heterozygosity, Home Oxygen Therapy, Human, Human Cell, Hydrogen Bond, Intellectual Impairment, Intelligence Quotient, Intractable Epilepsy, Ketamine, Lacosamide, Lamotrigine, Lennox Gastaut Syndrome, Levetiracetam, Magnetoencephalography, Male, Maternal Hypertension, Melatonin, Migraine, Missense Mutation, Molecular Dynamics, Molecular Dynamics Simulation, Mutation, Myoclonus Seizure, N Methyl Dextro Aspartic Acid Receptor, N Methyl Dextro Aspartic Acid Receptor 2D, N-Methyl-D-Aspartate, Neonatal Pneumonia, Neonatal Respiratory Distress Syndrome, Neuroimaging, Nuclear Magnetic Resonance Imaging, Phenobarbital, Premature Labor, Preschool, Preschool Child, Priority Journal, Protein Conformation, Proximal Interphalangeal Joint, Pyridoxine, Receptors, Respiratory Arrest, Sanger Sequencing, School Child, Single Photon Emission Computed Tomography, Sleep Disordered Breathing, Static Electricity, Stridor, Structure-Activity Relationship, Subglottic Stenosis, Superior Temporal Gyrus, Supramarginal Gyrus, Thiopental, Tonic Seizure, Valproic Acid, Wakefulness, Wechsler Intelligence Scale for Children, Whole Exome Sequencing}, pubstate = {published}, tppubtype = {article} } N-methyl-d-aspartate (NMDA) receptors are glutamate-activated ion channels that are widely distributed in the central nervous system and essential for brain development and function. Dysfunction of NMDA receptors has been associated with various neurodevelopmental disorders. Recently, a de novo recurrent GRIN2D missense variant was found in two unrelated patients with developmental and epileptic encephalopathy. In this study, we identified by whole exome sequencing novel heterozygous GRIN2D missense variants in three unrelated patients with severe developmental delay and intractable epilepsy. All altered residues were highly conserved across vertebrates and among the four GluN2 subunits. Structural consideration indicated that all three variants are probably to impair GluN2D function, either by affecting intersubunit interaction or altering channel gating activity. We assessed the clinical features of our three cases and compared them to those of the two previously reported GRIN2D variant cases, and found that they all show similar clinical features. This study provides further evidence of GRIN2D variants being causal for epilepsy. Genetic diagnosis for GluN2-related disorders may be clinically useful when considering drug therapy targeting NMDA receptors. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd |
Sudirman, R; Hussin, S S; Airij, A G; Hai, C Z Profile indicator for autistic children using EEG biosignal potential of sensory tasks Conference Institute of Electrical and Electronics Engineers Inc., 2018, ISBN: 9781538612774, (cited By 0). Abstract | Links | BibTeX | Tags: Autistic Children, Biomedical Signal Processing, Brain, Children with Autism, Electroencephalography, Electrophysiology, Entropy Approximations, Independent Component Analysis, MATLAB, Neural Networks, Neurological Problems, Sensory Analysis, Sensory Profiles, Sensory Stimulation, Wavelet Packet Transforms @conference{Sudirman2018136, title = {Profile indicator for autistic children using EEG biosignal potential of sensory tasks}, author = {R Sudirman and S S Hussin and A G Airij and C Z Hai}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058032461&doi=10.1109%2fICBAPS.2018.8527403&partnerID=40&md5=30dbb1596f4a0529332713c087bd788d}, doi = {10.1109/ICBAPS.2018.8527403}, isbn = {9781538612774}, year = {2018}, date = {2018-01-01}, journal = {2nd International Conference on BioSignal Analysis, Processing and Systems, ICBAPS 2018}, pages = {136-141}, publisher = {Institute of Electrical and Electronics Engineers Inc.}, abstract = {Electroencephalography (EEG) is a measure of voltages caused due to neural activities within the brain. EEG is a recommended tool for diagnosing neurological problems because it is non-invasive and can be recorded over a longer time-period. The children with Autism Spectrum Disorder (ASD) have difficulty in expressing their emotions due to their inability of proper information processing in brain. Therefore, this research aims to build a sensory profile with the help of EEG biosignal potential to distinguish among different sensory responses. The EEG signals acquired in this research identify different emotional states such as positive-thinking or super-learning and light-relaxation and are within the frequency range of 8-12 Hertz. 64 children participated in this research among which 34 were children with ASD and 30 were normal children. The EEG data was recoded while all the children were provided with vestibular, visual, sound, taste and vestibular sensory stimulations. The raw EEG data was filtered with the help of independent component analysis (ICA) using wavelet transform and EEGLAB software. Later, for building the sensory profile, entropy approximation, means and standard deviations were extracted from the filtered EEG signals. Along with that, the filtered EEG data was also fed to a neural networks (NN) algorithm which was implemented in MATLAB. Results from the acquired EEG signals depicted that during the sensory stimulation phase, the responses of all autistic children were in an unstable state. These findings will equip and aid their learning strategy in the future. © 2018 IEEE.}, note = {cited By 0}, keywords = {Autistic Children, Biomedical Signal Processing, Brain, Children with Autism, Electroencephalography, Electrophysiology, Entropy Approximations, Independent Component Analysis, MATLAB, Neural Networks, Neurological Problems, Sensory Analysis, Sensory Profiles, Sensory Stimulation, Wavelet Packet Transforms}, pubstate = {published}, tppubtype = {conference} } Electroencephalography (EEG) is a measure of voltages caused due to neural activities within the brain. EEG is a recommended tool for diagnosing neurological problems because it is non-invasive and can be recorded over a longer time-period. The children with Autism Spectrum Disorder (ASD) have difficulty in expressing their emotions due to their inability of proper information processing in brain. Therefore, this research aims to build a sensory profile with the help of EEG biosignal potential to distinguish among different sensory responses. The EEG signals acquired in this research identify different emotional states such as positive-thinking or super-learning and light-relaxation and are within the frequency range of 8-12 Hertz. 64 children participated in this research among which 34 were children with ASD and 30 were normal children. The EEG data was recoded while all the children were provided with vestibular, visual, sound, taste and vestibular sensory stimulations. The raw EEG data was filtered with the help of independent component analysis (ICA) using wavelet transform and EEGLAB software. Later, for building the sensory profile, entropy approximation, means and standard deviations were extracted from the filtered EEG signals. Along with that, the filtered EEG data was also fed to a neural networks (NN) algorithm which was implemented in MATLAB. Results from the acquired EEG signals depicted that during the sensory stimulation phase, the responses of all autistic children were in an unstable state. These findings will equip and aid their learning strategy in the future. © 2018 IEEE. |
Adib, N A N; Ibrahim, M I; Rahman, A A; Bakar, R S; Yahaya, N A; Hussin, S; Arifin, W N International Journal of Environmental Research and Public Health, 15 (11), 2018, ISSN: 16617827, (cited By 2). Abstract | Links | BibTeX | Tags: Adult, Article, Autism, Autism Spectrum Disorders, Caregiver, Child Care, Child Parent Relation, Children, Cross-Sectional Study, Factor Analysis, Female, Guideline, Health Personnel Attitude, Health Service, Health Worker, Human, Kelantan, Likelihood Functions, Likert Scale, Malaysia, Male, Maximum Likelihood Analysis, Mental Health, Mental Health Service, Parents, Parents Satisfaction Scale Malay Version, Personal Satisfaction, Practice Guideline, Psychological Rating Scale, Psychology, Publication, Questionnaires, Reproducibility, Reproducibility of Results, Satisfaction, Statistical Model, Statistics, Surveys, Tertiary Care Center, Translations, Validation Study, West Malaysia @article{Adib2018, title = {Translation and validation of the malay version of the parents’ satisfaction scale (Pss-m) for assessment of caregivers’ satisfaction with health care services for children with autism spectrum disorder}, author = {N A N Adib and M I Ibrahim and A A Rahman and R S Bakar and N A Yahaya and S Hussin and W N Arifin}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056090545&doi=10.3390%2fijerph15112455&partnerID=40&md5=53650806d46343cc3e95c9b30442f79c}, doi = {10.3390/ijerph15112455}, issn = {16617827}, year = {2018}, date = {2018-01-01}, journal = {International Journal of Environmental Research and Public Health}, volume = {15}, number = {11}, publisher = {MDPI AG}, abstract = {Background: A Malay version of Parent Satisfaction Scale (PSS-M) is needed to investigate the factors contributing to the Malay caregivers’ satisfaction with health care management for children with autism spectrum disorder (ASD). The aim of the study is to translate and validate the questionnaire to assess the caregivers’ satisfaction on health care services. Methods: A cross-sectional study was conducted among 110 caregivers of children with ASD aged between 2 and 17 years old that received treatment at two tertiary care centres in Kelantan. Permission to use the original version of the PSS questionnaire was obtained. The original English version of the PSS was translated into a Malay version following the 10 steps proposed by an established guideline. Pre-testing of the PSS was carried out with 30 caregivers before confirmatory factor analysis (CFA) was established using 110 caregivers. They were asked to assess their understanding of the questionnaire. The one-dimensional questionnaire consists of 11 items, including staff attitudes, availability of staff, supportiveness, and helpfulness. The 5-point Likert scale provided ratings from 1 (strongly disagree) to 5 (strongly agree). Confirmatory factor analysis was performed using a robust maximum likelihood estimator. Results: The analysis showed model fit data with good reliability. Conclusion: The PSS-M shows overall model fitness based on specific indices, with good construct validity and excellent absolute reliability to determine the satisfaction level of caregivers of children with ASD with respect to health care services. © 2018, MDPI AG. All rights reserved.}, note = {cited By 2}, keywords = {Adult, Article, Autism, Autism Spectrum Disorders, Caregiver, Child Care, Child Parent Relation, Children, Cross-Sectional Study, Factor Analysis, Female, Guideline, Health Personnel Attitude, Health Service, Health Worker, Human, Kelantan, Likelihood Functions, Likert Scale, Malaysia, Male, Maximum Likelihood Analysis, Mental Health, Mental Health Service, Parents, Parents Satisfaction Scale Malay Version, Personal Satisfaction, Practice Guideline, Psychological Rating Scale, Psychology, Publication, Questionnaires, Reproducibility, Reproducibility of Results, Satisfaction, Statistical Model, Statistics, Surveys, Tertiary Care Center, Translations, Validation Study, West Malaysia}, pubstate = {published}, tppubtype = {article} } Background: A Malay version of Parent Satisfaction Scale (PSS-M) is needed to investigate the factors contributing to the Malay caregivers’ satisfaction with health care management for children with autism spectrum disorder (ASD). The aim of the study is to translate and validate the questionnaire to assess the caregivers’ satisfaction on health care services. Methods: A cross-sectional study was conducted among 110 caregivers of children with ASD aged between 2 and 17 years old that received treatment at two tertiary care centres in Kelantan. Permission to use the original version of the PSS questionnaire was obtained. The original English version of the PSS was translated into a Malay version following the 10 steps proposed by an established guideline. Pre-testing of the PSS was carried out with 30 caregivers before confirmatory factor analysis (CFA) was established using 110 caregivers. They were asked to assess their understanding of the questionnaire. The one-dimensional questionnaire consists of 11 items, including staff attitudes, availability of staff, supportiveness, and helpfulness. The 5-point Likert scale provided ratings from 1 (strongly disagree) to 5 (strongly agree). Confirmatory factor analysis was performed using a robust maximum likelihood estimator. Results: The analysis showed model fit data with good reliability. Conclusion: The PSS-M shows overall model fitness based on specific indices, with good construct validity and excellent absolute reliability to determine the satisfaction level of caregivers of children with ASD with respect to health care services. © 2018, MDPI AG. All rights reserved. |