2020 |
Taresh, S; Ahmad, N A; Roslan, S; Ma’rof, A M; Zaid, S Brain Sciences, 10 (3), 2020, ISSN: 20763425, (cited By 0). Abstract | Links | BibTeX | Tags: Attitude to Disability, Autism, Cognition, Conceptual Framework, Education, Health Belief, Health Care, Health Care Personnel, Human, Interpersonal Communication, Mental Health, Physiotherapist, Psychological Aspect, Questionnaires, Review, School Teacher, Self Concept, Social Behaviour, Social Cognitive Theory, Social Interactions, Social Stigma, Teaching, Training @article{Taresh2020, title = {Pre-school teachers’ knowledge, belief, identification skills, and self-efficacy in identifying autism spectrum disorder (ASD): A conceptual framework to identify children with ASD}, author = {S Taresh and N A Ahmad and S Roslan and A M Ma’rof and S Zaid}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082661960&doi=10.3390%2fbrainsci10030165&partnerID=40&md5=806c3d699ffc9bd518bc0397b07598a8}, doi = {10.3390/brainsci10030165}, issn = {20763425}, year = {2020}, date = {2020-01-01}, journal = {Brain Sciences}, volume = {10}, number = {3}, publisher = {MDPI AG}, abstract = {Recently, the identification and detection of children with autism spectrum disorder (ASD) has become an essential issue under ASD intervention services. The high percentage of ASD among children requires preschool teachers to recognizse children’s abnormal development and identify them at an early stage, followed by referral to specialists. Therefore, this identification calls for a specific ability among preschool teachers, identified as knowledge, belief, identification skills, and self-efficacy (KBISSE). This conceptual framework aims to utilize the current literature to present a discussion on preschool teachers’ KBISSE in identifying children with ASD and making decisions to refer children suspected with ASD to specialists. The conceptual framework is discussed based on social cognitive theory (SCT) and the health belief model (HBM). The conceptual framework emphasizes the need for preschool teachers to be educated in ASD via an educational module that could increase teachers’ self-efficacy in identifying children with ASD. Besides, knowledge in ASD, belief in ASD, and identification skills are also necessary variables for building the educational module. The educational module is useful for guiding future research on preschool teachers’ identification of children with any disability, one of which is ASD, and subsequent specialist referral at an early stage. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.}, note = {cited By 0}, keywords = {Attitude to Disability, Autism, Cognition, Conceptual Framework, Education, Health Belief, Health Care, Health Care Personnel, Human, Interpersonal Communication, Mental Health, Physiotherapist, Psychological Aspect, Questionnaires, Review, School Teacher, Self Concept, Social Behaviour, Social Cognitive Theory, Social Interactions, Social Stigma, Teaching, Training}, pubstate = {published}, tppubtype = {article} } Recently, the identification and detection of children with autism spectrum disorder (ASD) has become an essential issue under ASD intervention services. The high percentage of ASD among children requires preschool teachers to recognizse children’s abnormal development and identify them at an early stage, followed by referral to specialists. Therefore, this identification calls for a specific ability among preschool teachers, identified as knowledge, belief, identification skills, and self-efficacy (KBISSE). This conceptual framework aims to utilize the current literature to present a discussion on preschool teachers’ KBISSE in identifying children with ASD and making decisions to refer children suspected with ASD to specialists. The conceptual framework is discussed based on social cognitive theory (SCT) and the health belief model (HBM). The conceptual framework emphasizes the need for preschool teachers to be educated in ASD via an educational module that could increase teachers’ self-efficacy in identifying children with ASD. Besides, knowledge in ASD, belief in ASD, and identification skills are also necessary variables for building the educational module. The educational module is useful for guiding future research on preschool teachers’ identification of children with any disability, one of which is ASD, and subsequent specialist referral at an early stage. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. |
2018 |
Paudel, Y N; Shaikh, M F; Shah, S; Kumari, Y; Othman, I Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy Journal Article European Journal of Pharmacology, 837 , pp. 145-155, 2018, ISSN: 00142999, (cited By 14). Abstract | Links | BibTeX | Tags: 3 Dioxygenase, Acetylsalicylic Acid, Adalimumab, Anakinra, Animals, Anti-Inflammatory Agents, Anxiety, Autacoid, Autism, Autism Spectrum Disorders, Behaviour Disorder, Belnacasan, Celecoxib, Cognition, Comorbidity, Complication, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitor, Cytokine, Cytokines, Depression, Dexmedetomidine, Disease Association, Dopaminergic Transmission, Electroencephalogram, Electroencephalography, Epilepsy, Epileptogenesis, Esculetin, High Mobility Group B1 Protein, Human, Ibuprofen, Icariin, IImmunoglobulin Enhancer Binding Protein, Immunology, Indoleamine 2, Inflammation, Inflammation Mediators, Infliximab, Interleukin 1beta, Interleukin 6, Minocycline, Nerve Cell Plasticity, Nervous System Development, Nervous System Inflammation, Neuroendocrine Regulation, Neurotransmitter Release, Nonhuman, Palmidrol, Paracetamol, Physiology, Priority Journal, Prostaglandin E2, Psychology, Review, SC 51089, Schizophrenia, Toll-Like Receptor 4, Transforming Growth Factor Beta, Tryptophan Hydroxylase, Tumor Necrosis Factor, Unclassified Drug @article{Paudel2018145, title = {Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy}, author = {Y N Paudel and M F Shaikh and S Shah and Y Kumari and I Othman}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053082063&doi=10.1016%2fj.ejphar.2018.08.020&partnerID=40&md5=27ff0199bae72f156425637a7ad02228}, doi = {10.1016/j.ejphar.2018.08.020}, issn = {00142999}, year = {2018}, date = {2018-01-01}, journal = {European Journal of Pharmacology}, volume = {837}, pages = {145-155}, publisher = {Elsevier B.V.}, abstract = {Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover, the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities. The neurobehavioral comorbidities discussed herein share a reciprocal and complex relationship with epilepsy, which ultimately complicates the treatment process in PWE. Understanding the mechanistic pathway by which these comorbidities are associated with epilepsy might be instrumental in developing therapeutic interventions. Inflammatory cytokine signaling in the brain regulates important brain functions including neurotransmitter metabolism, neuroendocrine function, synaptic plasticity, dopaminergic transmission, the kynurenine pathway, and affects neurogenesis as well as the neural circuitry of moods. In this review, we hypothesize that the complex relationship between epilepsy and its related comorbidities (cognitive impairment, depression, anxiety, autism, and schizophrenia) can be unraveled through the inflammatory mechanism that plays a prominent role in all these individual conditions. An ample amount of evidence is available reporting the role of inflammation in epilepsy and all individual comorbid condition but their complex relationship with epilepsy has not yet been explored through the prospective of inflammatory pathway. Our review suggests that epilepsy and its neurobehavioral comorbidities are associated with elevated levels of several key inflammatory markers. This review also sheds light on the mechanistic association between epilepsy and its neurobehavioral comorbidities. Moreover, we analyzed several anti-inflammatory therapies available for epilepsy and its neurobehavioral comorbidities. We suggest, these anti-inflammatory therapies might be a possible intervention and could be a promising strategy for preventing epileptogenesis and its related neurobehavioral comorbidities. © 2018 Elsevier B.V.}, note = {cited By 14}, keywords = {3 Dioxygenase, Acetylsalicylic Acid, Adalimumab, Anakinra, Animals, Anti-Inflammatory Agents, Anxiety, Autacoid, Autism, Autism Spectrum Disorders, Behaviour Disorder, Belnacasan, Celecoxib, Cognition, Comorbidity, Complication, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitor, Cytokine, Cytokines, Depression, Dexmedetomidine, Disease Association, Dopaminergic Transmission, Electroencephalogram, Electroencephalography, Epilepsy, Epileptogenesis, Esculetin, High Mobility Group B1 Protein, Human, Ibuprofen, Icariin, IImmunoglobulin Enhancer Binding Protein, Immunology, Indoleamine 2, Inflammation, Inflammation Mediators, Infliximab, Interleukin 1beta, Interleukin 6, Minocycline, Nerve Cell Plasticity, Nervous System Development, Nervous System Inflammation, Neuroendocrine Regulation, Neurotransmitter Release, Nonhuman, Palmidrol, Paracetamol, Physiology, Priority Journal, Prostaglandin E2, Psychology, Review, SC 51089, Schizophrenia, Toll-Like Receptor 4, Transforming Growth Factor Beta, Tryptophan Hydroxylase, Tumor Necrosis Factor, Unclassified Drug}, pubstate = {published}, tppubtype = {article} } Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover, the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities. The neurobehavioral comorbidities discussed herein share a reciprocal and complex relationship with epilepsy, which ultimately complicates the treatment process in PWE. Understanding the mechanistic pathway by which these comorbidities are associated with epilepsy might be instrumental in developing therapeutic interventions. Inflammatory cytokine signaling in the brain regulates important brain functions including neurotransmitter metabolism, neuroendocrine function, synaptic plasticity, dopaminergic transmission, the kynurenine pathway, and affects neurogenesis as well as the neural circuitry of moods. In this review, we hypothesize that the complex relationship between epilepsy and its related comorbidities (cognitive impairment, depression, anxiety, autism, and schizophrenia) can be unraveled through the inflammatory mechanism that plays a prominent role in all these individual conditions. An ample amount of evidence is available reporting the role of inflammation in epilepsy and all individual comorbid condition but their complex relationship with epilepsy has not yet been explored through the prospective of inflammatory pathway. Our review suggests that epilepsy and its neurobehavioral comorbidities are associated with elevated levels of several key inflammatory markers. This review also sheds light on the mechanistic association between epilepsy and its neurobehavioral comorbidities. Moreover, we analyzed several anti-inflammatory therapies available for epilepsy and its neurobehavioral comorbidities. We suggest, these anti-inflammatory therapies might be a possible intervention and could be a promising strategy for preventing epileptogenesis and its related neurobehavioral comorbidities. © 2018 Elsevier B.V. |
2017 |
Bhagat, V; Haque, M; Simbak, N B; Husain, R Emotional regulation in autism spectrum disorders: A new proposed model for regulating emotions through parent education Journal Article Journal of Global Pharma Technology, 9 (7), pp. 32-43, 2017, ISSN: 09758542, (cited By 0). Abstract | Links | BibTeX | Tags: Adaptive Behavior, Amygdala, Autism, Awareness, Cognition, Comorbidity, Conceptual Framework, Cost Benefit Analysis, Education, Emotion, Emotional Disorder, Emotionality, Health Care, Health Promotion, Human, Impulsiveness, Learning, Motivation, Parent Education, Perception, Practice Guideline, Prefrontal Cortex, Prevalence, Problem Behavior, Psychoeducation, Psychological Well Being, Review, Sex Difference, Social Behaviour, Social Cognition, Social Competence, Social Learning @article{Bhagat201732, title = {Emotional regulation in autism spectrum disorders: A new proposed model for regulating emotions through parent education}, author = {V Bhagat and M Haque and N B Simbak and R Husain}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021786235&partnerID=40&md5=ece2d7c28018f0c4526810e08e314461}, issn = {09758542}, year = {2017}, date = {2017-01-01}, journal = {Journal of Global Pharma Technology}, volume = {9}, number = {7}, pages = {32-43}, publisher = {Journal of Global Pharma Technology}, abstract = {Autism spectrum disorders (ASD) may affect all spheres of a child's life. One of the areas of the behavioral spectrum need to be focused is affected. Thus, the study is enthused in impaired emotional regulation (ER) affecting children with ASD. The significance of ER is related to that promoting adaptive behavior in children; indeed, disturbed ER in ASD children leads to emotional and behavioral problems. Commonly children with ASD lack adaptive ER strategies thus they react impulsively and inadequately to emotional stimuli thus it affects their psychological well-being. Though ER in ASD children is intrinsic the nurturing of these children with an understanding of ER can promote better psychological wellbeing. Thus, study objectives to examine a) the impact of ASD on their ER b) the impact of ER on the psychological wellbeing of children with ASD c) To develop awareness among these parents regarding the impact of ER on the psychological wellbeing of their ASD child. d) To propose a new model of parental education about ER and its significance on psychological wellbeing of ASD children. This study takes a base on the keenly examined past evidence on impaired ER in ASD children and its impact on the psychological wellbeing. Proposal for aiding ER through parental education has introduced. The conclusion drawn in this study is that the intervention can be more promising with educating parents regarding ER, may help their child to gain maximum from therapeutic intervention. The new proposed model of intervention extends the further scope for research in this regard. © 2009-2017, JGPT.}, note = {cited By 0}, keywords = {Adaptive Behavior, Amygdala, Autism, Awareness, Cognition, Comorbidity, Conceptual Framework, Cost Benefit Analysis, Education, Emotion, Emotional Disorder, Emotionality, Health Care, Health Promotion, Human, Impulsiveness, Learning, Motivation, Parent Education, Perception, Practice Guideline, Prefrontal Cortex, Prevalence, Problem Behavior, Psychoeducation, Psychological Well Being, Review, Sex Difference, Social Behaviour, Social Cognition, Social Competence, Social Learning}, pubstate = {published}, tppubtype = {article} } Autism spectrum disorders (ASD) may affect all spheres of a child's life. One of the areas of the behavioral spectrum need to be focused is affected. Thus, the study is enthused in impaired emotional regulation (ER) affecting children with ASD. The significance of ER is related to that promoting adaptive behavior in children; indeed, disturbed ER in ASD children leads to emotional and behavioral problems. Commonly children with ASD lack adaptive ER strategies thus they react impulsively and inadequately to emotional stimuli thus it affects their psychological well-being. Though ER in ASD children is intrinsic the nurturing of these children with an understanding of ER can promote better psychological wellbeing. Thus, study objectives to examine a) the impact of ASD on their ER b) the impact of ER on the psychological wellbeing of children with ASD c) To develop awareness among these parents regarding the impact of ER on the psychological wellbeing of their ASD child. d) To propose a new model of parental education about ER and its significance on psychological wellbeing of ASD children. This study takes a base on the keenly examined past evidence on impaired ER in ASD children and its impact on the psychological wellbeing. Proposal for aiding ER through parental education has introduced. The conclusion drawn in this study is that the intervention can be more promising with educating parents regarding ER, may help their child to gain maximum from therapeutic intervention. The new proposed model of intervention extends the further scope for research in this regard. © 2009-2017, JGPT. |
2016 |
Gravier, A; Quek, C; Duch, W; Wahab, A; Gravier-Rymaszewska, J Neural network modelling of the influence of channelopathies on reflex visual attention Journal Article Cognitive Neurodynamics, 10 (1), pp. 49-72, 2016, ISSN: 18714080, (cited By 8). Abstract | Links | BibTeX | Tags: Article, Artificial Neural Network, Attention, Autism, Calcium Channelopathy, Cell Structure, Cognition, Connectome, Electric Activity, Learning, Mathematical Analysis, Mathematical Model, Nerve Cell, Simulation, Visual Reflex @article{Gravier201649, title = {Neural network modelling of the influence of channelopathies on reflex visual attention}, author = {A Gravier and C Quek and W Duch and A Wahab and J Gravier-Rymaszewska}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955207541&doi=10.1007%2fs11571-015-9365-x&partnerID=40&md5=52f56b25f1d05a2d8eb0249e67e49f45}, doi = {10.1007/s11571-015-9365-x}, issn = {18714080}, year = {2016}, date = {2016-01-01}, journal = {Cognitive Neurodynamics}, volume = {10}, number = {1}, pages = {49-72}, publisher = {Springer Netherlands}, abstract = {This paper introduces a model of Emergent Visual Attention in presence of calcium channelopathy (EVAC). By modelling channelopathy, EVAC constitutes an effort towards identifying the possible causes of autism. The network structure embodies the dual pathways model of cortical processing of visual input, with reflex attention as an emergent property of neural interactions. EVAC extends existing work by introducing attention shift in a larger-scale network and applying a phenomenological model of channelopathy. In presence of a distractor, the channelopathic network’s rate of failure to shift attention is lower than the control network’s, but overall, the control network exhibits a lower classification error rate. The simulation results also show differences in task-relative reaction times between control and channelopathic networks. The attention shift timings inferred from the model are consistent with studies of attention shift in autistic children. © 2015, Springer Science+Business Media Dordrecht.}, note = {cited By 8}, keywords = {Article, Artificial Neural Network, Attention, Autism, Calcium Channelopathy, Cell Structure, Cognition, Connectome, Electric Activity, Learning, Mathematical Analysis, Mathematical Model, Nerve Cell, Simulation, Visual Reflex}, pubstate = {published}, tppubtype = {article} } This paper introduces a model of Emergent Visual Attention in presence of calcium channelopathy (EVAC). By modelling channelopathy, EVAC constitutes an effort towards identifying the possible causes of autism. The network structure embodies the dual pathways model of cortical processing of visual input, with reflex attention as an emergent property of neural interactions. EVAC extends existing work by introducing attention shift in a larger-scale network and applying a phenomenological model of channelopathy. In presence of a distractor, the channelopathic network’s rate of failure to shift attention is lower than the control network’s, but overall, the control network exhibits a lower classification error rate. The simulation results also show differences in task-relative reaction times between control and channelopathic networks. The attention shift timings inferred from the model are consistent with studies of attention shift in autistic children. © 2015, Springer Science+Business Media Dordrecht. |
2015 |
Bhagat, V; Jayaraj, J; Haque, M International Journal of Pharmacy and Pharmaceutical Sciences, 7 (11), pp. 7-12, 2015, ISSN: 09751491, (cited By 3). Abstract | Links | BibTeX | Tags: Anxiety, Autism, Caregiver, Child Behaviour, Child Parent Relation, Cognition, Coping Behaviour, Distress Syndrome, Emotion, Emotionality, Human, Intelligence, Mental Capacity, Parental Stress, Parents, Phenotype, Review, Self Concept @article{Bhagat20157, title = {Parent’s self-efficacy, emotionality, and intellectual ability impacting the intervention of autism spectrum disorders: A review proposed model for appraisal of intervention}, author = {V Bhagat and J Jayaraj and M Haque}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946575464&partnerID=40&md5=7384d5557b767097e456dee7c79128f7}, issn = {09751491}, year = {2015}, date = {2015-01-01}, journal = {International Journal of Pharmacy and Pharmaceutical Sciences}, volume = {7}, number = {11}, pages = {7-12}, publisher = {International Journal of Pharmacy and Pharmaceutical Science}, abstract = {Autism spectrum disorder (ASD) may affect all domains of a child’s life. Indeed, it impacts not only the child but also parents and siblings, causing disturbances in the family. The experience of parents with an autism spectrum disorder can be devastating; they have a demanding need to cope with complex situations in their lives. The presence of pervasive and severe deficits in children with ASD increases the adjusting demands of parents in their life situations, thus, nudging them into distress which in turn incapacitate them and lowers their efficiency to deal with these situations thereby reducing their self-efficacy. These parents are found with disturbances in emotional and intellectual components of their personalities. They end up being shattered in their interpersonal relationship and family life. Indeed, these aspects of parental distress rank lower in position and the focus rests on the treatment of ASD. Thus, the management of ASD incapacitating the parents of the deficit children to reach their fullest abilities remains questionable. Therefore, the objectives of this study are a) to examine the impact of emotionality, intellectual ability and self-efficacy of the intervention of autism spectrum disorder. b) To propose a new intervention model for ASD incorporating self-efficacy, emotional and mental ability c) To suggest the integration of this new model with the current intervention regimens to ensure better efficacy. This study, based on past evidence has keenly, examined the correlation of intellectual ability, emotionality and self-efficacy with the intervention of autism spectrum disorder. The results reveal that emotional and intellectual disturbances and impaired self-efficacy in the parents of children with ASD have an adverse impact on the intervention of ASD. A new model of intervention for ASD encompassing the above-mentioned essential components of parents’ personality has been proposed, and its integration with the existing treatment regimens has been suggested to reap an improved outcome. The study concludes by observing the fact that considerable improvement in the diagnosed child may not ameliorate the parent and family distress already present, especially at the time and expense of intervention can be even more detrimental to the overall personality of the parents. The new proposed model of intervention can pave the way for further research in this regard. © 2015, International Journal of Pharmacy and Pharmaceutical Science. All rights reserved.}, note = {cited By 3}, keywords = {Anxiety, Autism, Caregiver, Child Behaviour, Child Parent Relation, Cognition, Coping Behaviour, Distress Syndrome, Emotion, Emotionality, Human, Intelligence, Mental Capacity, Parental Stress, Parents, Phenotype, Review, Self Concept}, pubstate = {published}, tppubtype = {article} } Autism spectrum disorder (ASD) may affect all domains of a child’s life. Indeed, it impacts not only the child but also parents and siblings, causing disturbances in the family. The experience of parents with an autism spectrum disorder can be devastating; they have a demanding need to cope with complex situations in their lives. The presence of pervasive and severe deficits in children with ASD increases the adjusting demands of parents in their life situations, thus, nudging them into distress which in turn incapacitate them and lowers their efficiency to deal with these situations thereby reducing their self-efficacy. These parents are found with disturbances in emotional and intellectual components of their personalities. They end up being shattered in their interpersonal relationship and family life. Indeed, these aspects of parental distress rank lower in position and the focus rests on the treatment of ASD. Thus, the management of ASD incapacitating the parents of the deficit children to reach their fullest abilities remains questionable. Therefore, the objectives of this study are a) to examine the impact of emotionality, intellectual ability and self-efficacy of the intervention of autism spectrum disorder. b) To propose a new intervention model for ASD incorporating self-efficacy, emotional and mental ability c) To suggest the integration of this new model with the current intervention regimens to ensure better efficacy. This study, based on past evidence has keenly, examined the correlation of intellectual ability, emotionality and self-efficacy with the intervention of autism spectrum disorder. The results reveal that emotional and intellectual disturbances and impaired self-efficacy in the parents of children with ASD have an adverse impact on the intervention of ASD. A new model of intervention for ASD encompassing the above-mentioned essential components of parents’ personality has been proposed, and its integration with the existing treatment regimens has been suggested to reap an improved outcome. The study concludes by observing the fact that considerable improvement in the diagnosed child may not ameliorate the parent and family distress already present, especially at the time and expense of intervention can be even more detrimental to the overall personality of the parents. The new proposed model of intervention can pave the way for further research in this regard. © 2015, International Journal of Pharmacy and Pharmaceutical Science. All rights reserved. |
2014 |
Bhat, S; Acharya, U R; Adeli, H; Bairy, G M; Adeli, A Autism: Cause factors, early diagnosis and therapies Journal Article Reviews in the Neurosciences, 25 (6), pp. 841-850, 2014, ISSN: 03341763, (cited By 52). Abstract | Links | BibTeX | Tags: 4 Aminobutyric Acid, Adolescent, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Article, Assistive Technology, Attention, Autism, Autism Spectrum Disorders, Behaviour Therapy, Biological Marker, Brain, Child Development Disorders, Children, Cognition, Cystine, Developmental Disorders, Diseases, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emotion, Facial Expression, Functional Magnetic Resonance Imaging, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Human, Infant, Interpersonal Communication, Methionine, Nervous System Inflammation, Neurobiology, Neurofeedback, Oxidative Stress, Pervasive, Physiology, Preschool Child, Priority Journal, Psychoeducation, School Child, Social Interactions, Speech Therapy, Virtual Reality, Zonisamide @article{Bhat2014841, title = {Autism: Cause factors, early diagnosis and therapies}, author = {S Bhat and U R Acharya and H Adeli and G M Bairy and A Adeli}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925284617&doi=10.1515%2frevneuro-2014-0056&partnerID=40&md5=caaa32e66af70e70ec325241d01564c9}, doi = {10.1515/revneuro-2014-0056}, issn = {03341763}, year = {2014}, date = {2014-01-01}, journal = {Reviews in the Neurosciences}, volume = {25}, number = {6}, pages = {841-850}, publisher = {Walter de Gruyter GmbH}, abstract = {Autism spectrum disorder (ASD) is a complex neurobiological disorder characterized by neuropsychological and behavioral deficits. Cognitive impairment, lack of social skills, and stereotyped behavior are the major autistic symptoms, visible after a certain age. It is one of the fastest growing disabilities. Its current prevalence rate in the U.S. estimated by the Centers for Disease Control and Prevention is 1 in 68 births. The genetic and physiological structure of the brain is studied to determine the pathology of autism, but diagnosis of autism at an early age is challenging due to the existing phenotypic and etiological heterogeneity among ASD individuals. Volumetric and neuroimaging techniques are explored to elucidate the neuroanatomy of the ASD brain. Nuroanatomical, neurochemical, and neuroimaging biomarkers can help in the early diagnosis and treatment of ASD. This paper presents a review of the types of autism, etiologies, early detection, and treatment of ASD. © 2014 Walter de Gruyter GmbH.}, note = {cited By 52}, keywords = {4 Aminobutyric Acid, Adolescent, Agenesis of Corpus Callosum, Animal Assisted Therapy, Anticonvulsive Agent, Article, Assistive Technology, Attention, Autism, Autism Spectrum Disorders, Behaviour Therapy, Biological Marker, Brain, Child Development Disorders, Children, Cognition, Cystine, Developmental Disorders, Diseases, Dolphin, Dolphin Assisted Therapy, DSM-5, Early Diagnosis, Emotion, Facial Expression, Functional Magnetic Resonance Imaging, Functional Neuroimaging, Gaze, Glutathione, Glutathione Disulfide, Human, Infant, Interpersonal Communication, Methionine, Nervous System Inflammation, Neurobiology, Neurofeedback, Oxidative Stress, Pervasive, Physiology, Preschool Child, Priority Journal, Psychoeducation, School Child, Social Interactions, Speech Therapy, Virtual Reality, Zonisamide}, pubstate = {published}, tppubtype = {article} } Autism spectrum disorder (ASD) is a complex neurobiological disorder characterized by neuropsychological and behavioral deficits. Cognitive impairment, lack of social skills, and stereotyped behavior are the major autistic symptoms, visible after a certain age. It is one of the fastest growing disabilities. Its current prevalence rate in the U.S. estimated by the Centers for Disease Control and Prevention is 1 in 68 births. The genetic and physiological structure of the brain is studied to determine the pathology of autism, but diagnosis of autism at an early age is challenging due to the existing phenotypic and etiological heterogeneity among ASD individuals. Volumetric and neuroimaging techniques are explored to elucidate the neuroanatomy of the ASD brain. Nuroanatomical, neurochemical, and neuroimaging biomarkers can help in the early diagnosis and treatment of ASD. This paper presents a review of the types of autism, etiologies, early detection, and treatment of ASD. © 2014 Walter de Gruyter GmbH. |
Pillai, D; Sheppard, E; Ropar, D; Marsh, L; Pearson, A; Mitchell, P Using other minds as a window onto the world: Guessing what happened from clues in behaviour Journal Article Journal of Autism and Developmental Disorders, 44 (10), pp. 2430-2439, 2014, ISSN: 01623257, (cited By 17). Abstract | Links | BibTeX | Tags: Adolescent, Adult, Article, Autism, Child Development Disorders, Children, Clinical Article, Cognition, Controlled Study, Eye Movement, Eye Tracking, Facial Expression, Gaze, Human, Intelligence Quotient, Male, Measurement Accuracy, Mouth, Pathophysiology, Pervasive, Physiology, Psychological Aspect, Psychology, Retrodiction, Task Performance, Theory of Mind, Verbal Communication, Video Recording, Videotape Recording, Young Adult @article{Pillai20142430, title = {Using other minds as a window onto the world: Guessing what happened from clues in behaviour}, author = {D Pillai and E Sheppard and D Ropar and L Marsh and A Pearson and P Mitchell}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84912053354&doi=10.1007%2fs10803-014-2106-x&partnerID=40&md5=c3396f6f468e37e253c657f998993859}, doi = {10.1007/s10803-014-2106-x}, issn = {01623257}, year = {2014}, date = {2014-01-01}, journal = {Journal of Autism and Developmental Disorders}, volume = {44}, number = {10}, pages = {2430-2439}, publisher = {Springer New York LLC}, abstract = {It has been proposed that mentalising involves retrodicting as well as predicting behaviour, by inferring previous mental states of a target. This study investigated whether retrodiction is impaired in individuals with autism spectrum disorders (ASD). Participants watched videos of real people reacting to the researcher behaving in one of four possible ways. Their task was to decide which of these four ‘‘scenarios’’ each person responded to. Participants’ eye movements were recorded. Participants with ASD were poorer than comparison participants at identifying the scenario to which people in the videos were responding. There were no group differences in time spent looking at the eyes or mouth. The findings imply those with ASD are impaired in using mentalising skills for retrodiction. © Springer Science+Business Media New York 2014.}, note = {cited By 17}, keywords = {Adolescent, Adult, Article, Autism, Child Development Disorders, Children, Clinical Article, Cognition, Controlled Study, Eye Movement, Eye Tracking, Facial Expression, Gaze, Human, Intelligence Quotient, Male, Measurement Accuracy, Mouth, Pathophysiology, Pervasive, Physiology, Psychological Aspect, Psychology, Retrodiction, Task Performance, Theory of Mind, Verbal Communication, Video Recording, Videotape Recording, Young Adult}, pubstate = {published}, tppubtype = {article} } It has been proposed that mentalising involves retrodicting as well as predicting behaviour, by inferring previous mental states of a target. This study investigated whether retrodiction is impaired in individuals with autism spectrum disorders (ASD). Participants watched videos of real people reacting to the researcher behaving in one of four possible ways. Their task was to decide which of these four ‘‘scenarios’’ each person responded to. Participants’ eye movements were recorded. Participants with ASD were poorer than comparison participants at identifying the scenario to which people in the videos were responding. There were no group differences in time spent looking at the eyes or mouth. The findings imply those with ASD are impaired in using mentalising skills for retrodiction. © Springer Science+Business Media New York 2014. |
2013 |
Khowaja, K; Salim, S S A systematic review of strategies and computer-based intervention (CBI) for reading comprehension of children with autism Journal Article Research in Autism Spectrum Disorders, 7 (9), pp. 1111-1121, 2013, ISSN: 17509467, (cited By 28). Abstract | Links | BibTeX | Tags: Attention, Autism, Bibliographic Database, Children, Clinical Effectiveness, Clinical Observation, Cognition, Comprehension, Computer Assisted Therapy, Computer Based Intervention, Explicit Memory, Human, Learning, Linguistics, Motivation, Multimedia, Pretest Posttest Design, Priority Journal, Reading, Reading Comprehension, Review, Systematic Review, Treatment Outcome @article{Khowaja20131111, title = {A systematic review of strategies and computer-based intervention (CBI) for reading comprehension of children with autism}, author = {K Khowaja and S S Salim}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879609907&doi=10.1016%2fj.rasd.2013.05.009&partnerID=40&md5=6ba3e9315ee8b3cecb6248b97198313d}, doi = {10.1016/j.rasd.2013.05.009}, issn = {17509467}, year = {2013}, date = {2013-01-01}, journal = {Research in Autism Spectrum Disorders}, volume = {7}, number = {9}, pages = {1111-1121}, abstract = {This paper presents a systematic review of relevant published studies on reading comprehension for children with autism, focusing on vocabulary instruction and text comprehension instruction from years 2000 to 2011. This systematic review attempts to address three specific research questions: strategies of vocabulary instruction and text comprehension instruction used, computer-based intervention (CBI) used or developed during study, and the effectiveness of using CBI for teaching children with autism. There are five strategies of vocabulary instruction and seven strategies of text comprehension instruction. Results indicate that two strategies of vocabulary instruction, multimedia methods and explicit instruction were found to be more commonly used than the other three. On the same note, question answering strategy of text comprehension instruction was discovered to be used more often than the other six. Results also indicate that children with autism can benefit from the strategies of reading comprehension and that the use of CBI as a mode of instruction for reading comprehension improved learning of children. This is clearly evident judging from the performance of children between pre-tests and post-tests of studies in which CBI was used. However, due to heterogeneity of participants, this is not always the case; a few studies reported no improvement in the learning of children with autism. © 2013 Elsevier Ltd. Allrights reserved.}, note = {cited By 28}, keywords = {Attention, Autism, Bibliographic Database, Children, Clinical Effectiveness, Clinical Observation, Cognition, Comprehension, Computer Assisted Therapy, Computer Based Intervention, Explicit Memory, Human, Learning, Linguistics, Motivation, Multimedia, Pretest Posttest Design, Priority Journal, Reading, Reading Comprehension, Review, Systematic Review, Treatment Outcome}, pubstate = {published}, tppubtype = {article} } This paper presents a systematic review of relevant published studies on reading comprehension for children with autism, focusing on vocabulary instruction and text comprehension instruction from years 2000 to 2011. This systematic review attempts to address three specific research questions: strategies of vocabulary instruction and text comprehension instruction used, computer-based intervention (CBI) used or developed during study, and the effectiveness of using CBI for teaching children with autism. There are five strategies of vocabulary instruction and seven strategies of text comprehension instruction. Results indicate that two strategies of vocabulary instruction, multimedia methods and explicit instruction were found to be more commonly used than the other three. On the same note, question answering strategy of text comprehension instruction was discovered to be used more often than the other six. Results also indicate that children with autism can benefit from the strategies of reading comprehension and that the use of CBI as a mode of instruction for reading comprehension improved learning of children. This is clearly evident judging from the performance of children between pre-tests and post-tests of studies in which CBI was used. However, due to heterogeneity of participants, this is not always the case; a few studies reported no improvement in the learning of children with autism. © 2013 Elsevier Ltd. Allrights reserved. |
2020 |
Brain Sciences, 10 (3), 2020, ISSN: 20763425, (cited By 0). |
2018 |
Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy Journal Article European Journal of Pharmacology, 837 , pp. 145-155, 2018, ISSN: 00142999, (cited By 14). |
2017 |
Emotional regulation in autism spectrum disorders: A new proposed model for regulating emotions through parent education Journal Article Journal of Global Pharma Technology, 9 (7), pp. 32-43, 2017, ISSN: 09758542, (cited By 0). |
2016 |
Neural network modelling of the influence of channelopathies on reflex visual attention Journal Article Cognitive Neurodynamics, 10 (1), pp. 49-72, 2016, ISSN: 18714080, (cited By 8). |
2015 |
International Journal of Pharmacy and Pharmaceutical Sciences, 7 (11), pp. 7-12, 2015, ISSN: 09751491, (cited By 3). |
2014 |
Autism: Cause factors, early diagnosis and therapies Journal Article Reviews in the Neurosciences, 25 (6), pp. 841-850, 2014, ISSN: 03341763, (cited By 52). |
Using other minds as a window onto the world: Guessing what happened from clues in behaviour Journal Article Journal of Autism and Developmental Disorders, 44 (10), pp. 2430-2439, 2014, ISSN: 01623257, (cited By 17). |
2013 |
A systematic review of strategies and computer-based intervention (CBI) for reading comprehension of children with autism Journal Article Research in Autism Spectrum Disorders, 7 (9), pp. 1111-1121, 2013, ISSN: 17509467, (cited By 28). |